Title of manuscript (The title should be followed by the words “Case Report”

Title of manuscript (The title should be followed by the words

“Case Report”

The names and affiliations of the authors: The names should be completed, no abbreviations and in the order: First Name Middle Name Last Name. It is important that the name be spelled in that order; this is how they will be submitted to PUBMED.

The name and email address of the corresponding author.

Abstract

A single unstructured paragraph that should include 1) what is unique about this case and what does it add to the scientific literature; 2) the Main symptoms and/or important clinical findings; 3) the main diagnoses, therapeutic interventions, and outcomes; and 4) What is the main “take-away” lesson(s) from this case.

Keywords:

Introduction

Include your introduction here. The introduction should be one or two paragraphs summarizing why this case is unique (may include references)

Patient and observation

Include your structured case report here with the following, relevant sections below:

Patient Information: 1) De-identified patient specific information; 2) reasons for encounter/consultation or primary concerns and symptoms of the patient; 3) Medical, family, and psycho-social history including relevant genetic information; 4) Relevant past interventions with outcomes.

Clinical Findings: Describe significant physical examination (PE) and important clinical findings.

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Timeline of current episode: Historical and current information from this episode of care organized as a timeline.

Diagnostic assessment: Diagnostic testing (such as PE, laboratory testing, imaging, surveys), diagnostic challenges (such as access to testing due to limited technical platform, financial, or cultural)

Diagnosis: presumptive/final diagnosis, (other diagnoses considered); also include the p rognosis (such as staging in oncology) where applicable.

Therapeutic interventions: If a therapeutic intervention was provided, Types of therapeutic intervention (such as pharmacologic, surgical, preventive, self-care);

administration of therapeutic intervention (such as dosage, strength, duration); changes in therapeutic intervention (with rationale)

Follow-up and outcome of interventions: Clinician and patient-assessed outcomes (if available); Important follow-up diagnostic and other test results; Intervention

adherence and tolerability (How was this assessed?); adverse and unanticipated events.

Patient Perspective: The patient should share their perspective in one to two paragraphs on the treatment(s) they received.

Informed Consent: Did the patient give informed consent? Please provide details.

Discussion

Include your discussion here. The discussion should focus on:

 A scientific discussion of the strengths AND limitations associated with this case report.

 Discussion of the relevant medical literature with references

 The scientific rationale for any conclusions (including assessment of possible causes)

Conclusion

The paragraph conclusion should include the primary “take-away” lessons of this case report (without references).

Competing interests

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Declare any competing interests here. If there are no competing interests to declare us the mention: The authors declare no competing interest.

Authors’ contributions

Specify the contribution to the work and write-up of the manuscript for each person listed as author.

Acknowledgements (if any)

If any, mention it here.

List of tables and figures (if any)

List all tables and figures (if any) included in the manuscript, with their detailed legend:

Example. Note that Tables should be included at the end of the manuscript, after the reference section. Figures should be uploaded during the submission process.

Table 1 : XXXX Table 2 : XXXXX Figure 1 : XX Figure 2 : XXX

References

Include your reference list here. Ensure that the reference list is formatted according to the journal standards.

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