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Heating behavior of magnetic iron oxide nanoparticles at clinically relevant concentration

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Academic year: 2021

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Heating behavior of iron oxide nanoparticles at high concentrations

Philipp Lemala,, Sandor Baloga, Christoph Geersa, Patricia Taladriz-Blancoa, Andrea Palumboa, Ann M. Hirtb, Barbara Rothen-Rutishausera, Alke Petri-Finka,c,*

a

Adolphe Merkle Institute, University of Fribourg, Chemin des Verdiers 4, CH-1700 Fribourg, Switzerland

b

Institute for Geophysics, ETH Zurich, Sonneggstrasse 5, CH-8092 Zurich, Switzerland c

Chemistry Department, University of Fribourg, Chemin du Museé 9, CH-1700 Fribourg Switzerland

* Corresponding authors: [email protected]

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Heating slope measurements and calculated SAR for small spheres

Suppl. Figure 1. A) Measurements of heating slope as a function of SPIONs concentration for small spheres and B) Calculated SAR value as a function of particle concentration. A) Data points represent triplicate experiments where small spheres exhibited detectable heating signals, close to the detection limit of the LIT system.[1] Small spheres show a linear trend in their heating slope as mentioned in the manuscript. B) Linearity in heating slopes resulted in stable SAR values for small spheres, in good agreement with the other screened nanoparticles. Error bars represent SAR calculation of triplicate heating slopes measurements. Line is included as a guide for eyes.

Reference

[1]

P. Lemal, C. Geers, C. A. Monnier, F. Crippa, L. Daum, D. A. Urban, B.

Rothen-Rutishauser, M. Bonmarin, A. Petri-Fink, and T. L. Moore, “Lock-in thermography as

a rapid and reproducible thermal characterization method for magnetic nanoparticles,”

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