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Design evaluation and optimization for models of hepatitis C viral dynamics

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Academic year: 2021

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Table 2: Values of the parameters used in the simulations (on their natural scale), according to four different patterns of viral decline in the population (Fig 2)
Table 3: Expected SE for a sample size of 30 patients, according to five popular designs and four different sets of parameter values, corresponding to four patterns of viral kinetics during Peg-IFN based therapy.
Table 4: Optimal designs according to the maximum number of samples M allowed per patient for a fixed number of N ∗ M = 240 sample measurements for each marker, similarly to design D 1 (Table 1)

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