HAL Id: hal-00491971
https://hal.archives-ouvertes.fr/hal-00491971
Submitted on 14 Jun 2010
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Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin
B-Cdc2/PP2A balance.
Andrew Burgess, Suzanne Vigneron, Estelle Brioudes, Jean-Claude Labbé, Thierry Lorca, Anna Castro
To cite this version:
Andrew Burgess, Suzanne Vigneron, Estelle Brioudes, Jean-Claude Labbé, Thierry Lorca, et al.. Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance.. Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 2010, 107 (28), pp.12564-9. �10.1073/pnas.0914191107�.
�hal-00491971�
Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the
cyclin B-Cdc2/PP2A balance
Andrew Burgess, Suzanne Vigneron, Estelle Brioudes, Jean-Claude Labbé, Thierry Lorca*
1and Anna Castro*
1BIOLOGICAL SCIENCES: Cell Biology
Running title: Human Greatwall controls mitosis through PP2A Key Words: Greatwall, PP2A, cyclin B-Cdc2, Human Cells, SAC
Universités Montpellier 2 et 1, Centre de Recherche de Biochimie Macromoléculaire, CNRS UMR 5237, IFR 122, 1919 Route de Mende, 34293 Montpellier cedex 5, France
Phone 33 4 67 61 33 30 Fax 33 4 67 52 15 59
*Corresponding author E-mails: anna.castro@crbm.cnrs.fr and thierry.lorca@crbm.cnrs.fr
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