• Aucun résultat trouvé

KPC-50 confers resistance to ceftazidime-avibactam associated with reduced carbapenemase activity

N/A
N/A
Protected

Academic year: 2021

Partager "KPC-50 confers resistance to ceftazidime-avibactam associated with reduced carbapenemase activity"

Copied!
1
0
0

Texte intégral

(1)

KPC-3 MSLYRRLVLLSCLSWPLAGFSATALTNLVAEPFAKLEQDFGGSIGVYAMDTGSGATVSYRAEERFPLCSSFKGFLAAAVLARSQQQAGLLDTPIRYGKNA KPC-41 KPC-50 ---164 179 ½ ½ KPC-3 LVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGPAGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAA KPC-41 KPC-50 ---269 270 276 277 ½ ½ ½ ½ KPC-3 PQRQQFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGVYGTANDYAVVWPTGRAPIVLAVYTRAPNK///DDKYSEAV///IAAAARLALEGLGVNGQ KPC-41 ---PNK---///---KPC-50

---///---EAV---Figure S1. Alignment of the KPC-50 amino acid sequence in comparison with the KPC-3 ancestor and the KPC-41 variant conferring resistance to CZA.

Dashes indicate identical amino acids between sequences, and slashes indicate absence of amino acids at the corresponding positions. Shaded amino

acids indicate conserved motifs found within class A ß-lactamases. Boldened amino acids indicate the omega-loop of KPC-type enzymes.

Références

Documents relatifs

The vertical flux by dust mode is calculated as the sum of the contributions of each wind bin discretization and then distributed in the three SPLA aerosol modes: fine mode

However, in order to present the information in a readily recognizable fashion we combine the theoretical predictions of the charging time (Fig. The latter

Celui qui donne le vertige des sentiments Qui écarte les jambes dans notre gorge Qui respire fatalement par notre cuir Celui qui salue les gens à travers la brèche Qui accable

Oeuvre d’Art par Aldo Cruces-Newhall MathsLibres.com vous shouhaite Joyeux Noël... Comptage de 12 Jours de Noël par 10 (A) Réponses Comptage de dix lords

acquisition and performance of a more complex bilat- eral obstacle stepping task compared to unilateral ob- stacle stepping in PD patients and healthy age-matched control subjects..

We studied the e Vects of spatial pattern of resident plant communities on Wtness of genotypes from the native and introduced ranges of two worldwide invasive species, Centaurea

original objects’ shape was fully destroyed; (2) succes- sively splitting the cracker in six small pieces also resulted in high spatial ambiguity and destroyed the shape of the

Although deep white matter hyperintensities (DWMH) were more frequently associated with ischemia in depressed patients, mainly when located in the dorsolateral prefrontal cortex [ 134