Table 2: Genes differentially expressed in GASCs and control stromal cells. FCA: absolute fold change, GO_BP: gene ontology biological process, NA: not annotated, ND:
not determined.
Gene Name Accession Number Description P-value FCA GO_BP
Upregulated genes
CDH6 NM_004932 Cadherin-6 4.2 x 10-4 5.0 [homophilic cell adhesion]
NRGN NM_006176 Neurogranin 2.9 x 10-3 4.1 [nervous system development]
RAB20 NM_017817 Ras-related protein Rab-20 3.2 x 10-3 3.3 [small GTPase mediated signal transduction]
HIST1H4D NM_003539 Histone H4 4.1 x 10-3 2.8 [nucleosome assembly]
CCDC99 NM_017785 Coiled-coil domain-containing protein 99 8.5 x 10-4 2.8 [cell division]
MYH11 NM_002474
NM_022844 Myosin-11 3.6 x 10-4
4.3 x 10-4 137.3
134.3 [smooth muscle contraction]
TLE3 NM_005078 Transducin-like enhancer protein 3 2.9 x 10-3 2.5 [regulation of transcription, DNA dependent]
AKAP12 NM_144497 A-kinase anchor protein 12 (gravin) 3.3 x 10-3 2.1 [positive regulation of protein kinase A signaling cascade]
DHFR NM_000791 Dihydrofolate reductase 4.4 x 10-3 2.0 [tetrahydrofolate metabolic
process]
A_24_P333077 A_24_P333077 NA 5 x 10-3 2.5 ND
BX6448831 BX6448831 NA 5 x 10-3 2.6 ND
Downregulated genes
C10orf110 BC050694 Uncharacterized protein C10orf110 2.4 x 10-5 3.4 ND
APOL6 NM_030641 Apolipoprotein L6 3.3 x 10-3 3.6 [lipoprotein metabolic process]
GCNT3 ENST00000267857 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-
acetylglucosaminyltransferase 3 1.5 x 10-3 2.6 [protein amino O-linked glycosylation]
HIST1H2AC ENST00000314088 Histone H2A type 1-C 5.4 x 10-4 2.0 [nucleosome assembly]
LYPLAL1 NM_138794 Lysophospholipase-like protein 1 8 x 10-4 2.5 ND PDE4DIP NM_001002811 Phosphodiesterase 4D interacting protein isoform 3
(Myomegalin) 1.6 x 10-3 2.4 ND
SLC39A11 NM_139177 Zinc transporter ZIP11 2.2 x 10-3 2.2 [zinc ion transport]
DSCR1L1 NM_005822 Calcipressin-2 (RCAN2) 3.4 x 10-3 2.2 [calcium-mediated signaling]
AK095564 AK095564 NA 2.9 x 10-3 2.7 ND
THC2740111 THC2740111 NA 4.2 x 10-3 2.1 ND
THC2688736 THC2688736 NA 1.5 x 10-3 2.9 ND
