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Early growth response protein 1 (Egr-1) expression by Insulin-like growth factor 1 (IGF-1) involves MAPKs and PKB pathways

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Academic year: 2021

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Figure 1.1 Structure of insulin-like growth factor-1 (IGF-1) amino acid sequence.   IGF-1 is a single copy of 70 amino acid cyclic protein with three disulphide bridges linked  by cysteine residues
Figure 1.2 Insulin-like growth factor-1 (IGF-1) processing leading to mature IGF-1.   The Igf1 gene is first translated into a Pre-pro-IGF-1 precursor protein that includes a signal  peptide, signal peptide cleavage site, IGF-1, pro-protein convertase site
Figure 1.3 Schematic representation of Insulin-like growth fcator-1 (IGF-1).
Figure 1.5 Regulatory regions of the human Egr-1 gene.
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