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Degradable Spirocyclic Polyacetal-Based Core-Amphiphilic Assemblies for Encapsulation and Release of Hydrophobic Cargo

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Academic year: 2021

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Figure 1. (a) 1 H NMR of 7; (b) refractive index (RI) traces in the SEC analysis of 7 and 8 in DMF; (c) DSC analysis of 7 and 8 showing amorphous spirocyclic polyacetals at room temperature
Figure 2 for 7, the decrease in intensity of the peak at 5.37 ppm, corresponding to the acetal proton, and the concurrent increase in the intensity of the peak at 9.88 ppm, corresponding to the formation of arylaldehyde derivative, is a strong evidence of
Figure 3. (a,b) TEM and AFM images of P1. Inset showing the DLS data and a cartoon representa-
Figure 4. (a) DLS data for the Nile red-encapsulated P1 in water at room temperature as well as those incubated at 37 °C
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