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Mastocytosis in mice expressing human Kit receptor with the activating Asp816Val mutation.

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Academic year: 2021

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Table I. Mastocytosis in Bchm/Asp816Val Kit transgenic mice Age of mice
Figure 2. Increased number of tissular MCs in Bchm/Asp816Val Kit  transgenic mice. Paraffin-embedded sections of spleen (A), skin (B), stomach  (C), and heart (D) from old ( 12 mo) transgenic (n  28) and  nontrans-genic (n   22) littermates were stained
Figure 3. Growth factor–independent Kit phosphorylation and  proliferation of BMMCs from transgenic mice

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