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Optimal Threshold Determination for Interpreting Semantic Similarity and Particularity: Application to the Comparison of Gene Sets and Metabolic Pathways Using GO and ChEBI

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Figure

Table 1. Patterns of similarity and particularity Notation sim(A, B) par(A, B) par(B, A)
Table 2. Semantic similarity thresholds for Wang’s and Lin’s measures Wang Lin τ N Genes are not similar under τ S Genes aresimilarabove τ sim Threshold minimizingFP and FN τ N Genes are not similarunder τ S Genes aresimilarabove τ sim Threshold minimizing
Table 4. Similarity threshold variations considering full and partial datasets (Lin’s measure)
Table 7. Evolution in patterns in results on HomoloGene intra-group MF comparisons MF
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