Chapitre 5 : Discussion
5.4 Conclusion et futures pistes de recherche
5.4.2 Futures pistes de recherche
À part leurs impacts sur le sommeil (Gaillard et al., 1973) et la santé physique (Rogers et al., 2007), il s’avère que les benzodiazépines ont un impact délétère sur plusieurs fonctions cognitives (Barker et al., 2004a; Stewart, 2005). Des études suggèrent qu’il existe une association entre une consommation chronique de cette classe d’hypnotiques et le développement de la démence (une augmentation de 50 % de risque) (Gage et al., 2012). Plus précisément, l’utilisation des BZD aurait un impact négatif sur la mémoire, l’attention, la concentration et les performances psychomotrices (Barker et al., 2004a). Or, un sevrage seul de BZD ne s’avère pas suffisant pour rétablir complètement les fonctions cognitives affectées. Des études ont montré que des résidus de déficits cognitifs persistent même après un sevrage complet (Barker et al., 2004b, 2005).
À partir de ces notions, il serait intéressant, dans un futur proche, de vérifier l’effet de la TCCI sur les fonctions cognitives après le sevrage des BZD. L’hypothèse à vérifier serait de voir si l’ajout de la TCCI au sevrage aboutirait à une meilleure récupération des fonctions cognitives affectées, à l’opposé d’un sevrage seul. Et si c’est le cas, cette amélioration pourrait être due à l’amélioration des paramètres de sommeil ciblés par la TCCI.
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