augmentés dans le muscle squelettique de rat normal rendu

hyperinsulinémique par administration d'insuline pendant six semaines ^(136):

la pyruvate déshydrogénase de ces muscles squelettiques montre aussi ^une augmentation

de son

activation

à ^la ^fin ^des

^six^semaines

^de

traitement à I'insuline ^(136).

Ainsi, lorsqu'on considère

les

résultats

in vivo ou in vitro, les

effets de I'hyperinsulinémie sur ^Iemétabolisme du glucose demeurent contradictoires Mon travail est donc

de

créer une hyperinsulinémie chronique par infusion d'insuline chez un rat normal pendant quatre jours et d'étudier ^I'effetde cette hyperinsulinémie sur ^lemétabolisme du ^glucose.

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Dans le document Etudes des conséquences physiopathologiques de l'hyperinsulinémie: son impact dans la compréhension du développement de l'obésité chez le rat (Page 46-51)

augmentés dans le muscle squelettique de rat normal rendu

de son

à la fin des

de

les

in vivo ou in vitro, les

de

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F,

B; ln vivo

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