Top PDF Engrailed genes in mammary development and tumorigenesis
Engrailed genes in mammary development and tumorigenesis
... HOXC6 is oflen overexpressed in human leukemia yet Hoxc6 transcripts were found to decrease during pregnancy when the mammaiy gland is highly proliferative and HOXC6 is expressed at low [r] ...
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Loss of Panx1 Impairs Mammary Gland Development at Lactation: Implications for Breast Tumorigenesis
... expressed in the mammary gland Panx1 has an ubiquitous expression profile and has been reported in the mouse mammary gland based on expression profiling arrays in NCBI ’s gene ...
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Luminal Progenitors Restrict Their Lineage Potential during Mammary Gland Development
... ] and examined the clonal growth of Notch1-expressing cells in the presence of three differ- ent hormones: β-estradiol (β-2E), progesterone (Pg) or prolactin ...d in culture, we observed a net ...
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BRCA1 expression during prenatal development of the human mammary gland
... Brca1 in cellular dierentiation and morphogenesis has been obtained in mouse models during ...human and mouse genes, very few data on BRCA1 expression in human fetal tissues are ...
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The Prion-like protein Shadoo is involved in mouse embryonic and mammary development and differentiation
... tissue and genotype were performed. Differentially expressed genes between FVB/NJ and FVB/NJ Sprn-knockout tissues were identified following normalization of the raw data, with fold chance ratios ...
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Identification, for ruminants, of genes and gene networks involved in differentiation and activity of the mammary gland
... impaired mammary gland development, characterized by decreased epithelial proliferation and alveolar development (Cases et ...Nevertheless, genes involved in milk lipid ...
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Multimodal In Vivo Imaging of Tumorigenesis and Response to Chemotherapy in a Transgenic Mouse Model of Mammary Cancer
... possible in order to avoid unnecessary drug exposure. Functional and metabolic properties of tissues, including tumors, respond more rapidly than gross anatomy to changes in the environment; ...
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Myc is required for beta-catenin-mediated mammary stem cell amplification and tumorigenesis.
... Myc-deficient mammary basal cells showed impaired expression of numerous genes involved in important cell functions, including metabolism, replication, protein syn- thesis and the cell cycle, ...
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Mechanotransduction's Impact on Animal Development, Evolution, and Tumorigenesis
... HYPERPROLIFERATION AND INCREASED STIFFNESS IN TUMOR DEVELOPMENT MECHANICALLY REACTIVATES EMBRYONIC β-CATENIN–DEPENDENT DEVELOPMENTAL PATHWAYS Our understanding of tumor progression has progressed ...
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RIP140 increases APC expression and controls intestinal homeostasis and tumorigenesis.
... -catenin and overexpression of the β - catenin target genes : Cyclin D1 and c-Myc ...identified in human cancer cells through its interaction with estrogen receptor α ...receptors and ...
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Sexual dimorphism in adrenal gland development and tumorigenesis
... 269 genes differentially expressed in males vs females, 71 of which were regulated by changes in the androgenic milieu, suggesting that in addition to male sex hormones, other potential ...
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Denervation suppresses gastric tumorigenesis
... denervation in metastatic lymph nodes or other organs remains unclear and needs to be further investigated in suitable ...38), and a recent report has linked sympathetic nerves to prostate ...
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Chromatin assembly factors and heterochromatin organization during cell prolifertaion, tumorigenesis and in quiescence
... established and removed by a series of enzymes, including histone acetyl transferases (HAT), histone deacetylases (HDAC), histone methyl transferases (HMT) and histone demethylases ...(HD). In each ...
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Comment faire beaucoup avec peu dans le système nerveux - Engrailed recrute la mitochondrie
... veuse. Engrailed, une homéoprotéine qui intervient très tôt dans la spécification du territoire mésencéphalique dans le cerveau embryonnaire, contribue plus tard au guidage et à la stabilisation des axones ...
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The roles of the NOOT-BOP-COCH-LIKE genes in the symbiotic organ identity and in plant development
... generally in front of a xylem pole but sometimes the infection occurs facing a phloem pole (Hirsch 1992; Heidstra et ...consists in an uninfected nodule ...enriched in large ...zone and the ...
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Complex interplay between {beta}-catenin signalling and Notch effectors in intestinal tumorigenesis.
... early in b -catenin-induced intestinal tumori- genesis, by analysing Hes1 expression in a conditional mouse model with acute APC loss in the adult intestinal epithelium (Apc lox/lox Vil-CreER T2 ...3 ...
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Alternative splicing regulates vesicular trafficking genes in cardiomyocytes during postnatal heart development
... lysed in HEPES-sucrose buffer (10 mM HEPES pH ...EDTA, and proteases inhibitors) using Bullet blender (Next Advance) equipment and SDS was added (final concentration: 1% ...ON and 30 sec OFF) ...
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Expression profiling of development related genes in rice plants ectopically expressing AtTOR
... The seven times diluted cDNA was used for qRT-PCR analysis of different developmental genes using SYBR Green ® Premix (Takara Bio, Clonetech, USA). The primers used in qRT-PCR have been listed in ...
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Alkylation-induced colon tumorigenesis in mice deficient in the Mgmt and Msh6 proteins
... mutations and cell death that result from alkylation ...silencing in a variety of human cancers including nearly half of sporadic colorectal cancers, suggesting that this loss maybe ...AOM and ...
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B Cells Promote Pancreatic Tumorigenesis
... tumor and the late stages at diagnosis. This is reflected in the abysmal 5-year survival rate of ~7% and the harsh standard-of-care (SOC) for ...surgery in eligible patients, is gemcitabine, ...
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