bipolar disorder type I
Clinical expression of bipolar disorder type I as a function of age and polarity at onset: convergent findings in samples from France and the United States.
... bipolar I samples from Europe and the USA 5-11 . Early-onset BD1 has been associated with a particular pattern of clinical expression (psychotic features during episodes), a more severe course (rapid ...
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Molecular characteristics of Human Endogenous Retrovirus type-W in schizophrenia and bipolar disorder.
... Statistical analyses excluding Bipolar Disorder Patients treated with Valproate. 0.575 0.0006 Variables BP,N=91 SZ,N=45 Controls,N=73 P for all P BP vs TEM P BP vs SZ P SZ vs TEM RNA 1.62 (4.6) 0.84 (0.5) ...
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A DNA methylation signature discriminates between excellent and non-response to lithium in patients with bipolar disorder type 1
... for bipolar disorders (BD), but response rates are highly ...BD type 1 (15 excellent-responders (LiERs) versus 11 non‑responders (LinRs)) were used for targeted enrichment of cpG rich genomic regions ...
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An ASMT variant associated with bipolar disorder influences sleep and circadian rhythms: a pilot study.
... with bipolar disorder (type I, II or NOS), according to DSM-IV criteria (American Psychiatric Association, 2000), (ii) euthymic, with both a Montgomery –Asberg Depression Rating Scale (MADRS) ...
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Genetic contribution to the aggregation of schizophrenia and bipolar disorder in multiplex consanguineous Pakistani pedigrees
... Segregation analyses were done using an in-house Python script called SV-Segregation (Structural variant-Segregation). Firstly, raw calls from each same sample are filtered by user- defined thresholds and de-fragmented ...
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Common and rare variant analysis in early-onset bipolar disorder vulnerability.
... in bipolar patients, we screened all coding exons of PLCXD3 in 334 French subjects (204 patients with early-onset BD and 130 patients with late-onset ...BD type I and obsessive compulsive ...mood ...
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Violent criminal behavior in the context of bipolar disorder: Systematic review and meta-analysis
... A crime is violent when a victim is harmed by or threatened with violence (“National Institute of Justice,” 2017). Its definition may vary depending on national legal definitions according to: type of acts ...
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The HLA-G low expressor genotype is associated with protection against bipolar disorder.
... (type I or II), consecutively admitted to three French university-affiliated psychiatry departments (Paris-Créteil, Bordeaux and Nancy), were interviewed by trained psychiatrists, using the French version ...
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en fr Search for susceptibility genes of early-onset bipolar disorder Recherche de gènes de vulnérabilité aux troubles bipolaires
... de type I à début précoce (OR=9,3 ; IC(1,6-54,8) ; p=0,008), mais ces résultats ne sont plus significatifs après correction de Bonferroni (Etain et ...
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Identification of shared risk loci and pathways for bipolar disorder and schizophrenia
... Materials and methods Sample description The analyses were performed using data from our previous GWAS of BD (9,747 patients and 14,278 controls) [ 12 ]. This GWAS dataset combined: (i) the MooDS data (collected ...
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Molecular Mechanisms of Bipolar Disorder: Progress Made and Future Challenges
... FIGURE 2 | Mitochondrial dysfunction in BD. In BD cells, impaired oxidative phosphorylation results in a metabolic switch to glycolysis and lactate biosynthesis, with concomitant intracellular pH decrease. Decreased ...
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A systematic review on sleep alterations anticipating the onset of bipolar disorder
... 4.1.4. Circadian rhythm alterations In this review scant data concerning alterations in circadian rhythms were returned. A lower likelihood of conversion for the “extreme evening type ” pattern of circadian rhythm ...
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Cortical Volume Alterations in Conduct Disordered Adolescents with and without Bipolar Disorder.
... BD type I, our findings suggests the neurological underpinnings of bipolar disorder are consistent with other BD samples despite differences in patient settings and comorbid ...
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Immunoglobulin sub-class distribution in bipolar disorder and schizophrenia: potential relationship with latent Toxoplasma Gondii infection
... (type I and II), and SZ meeting the DSM-IV criteria [ 2 ], consecutively admitted/consulted at two French university-affiliated psychiatric departments, (Henri Mon- dor hospital, Créteil, University of ...
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Cytomegalovirus seropositivity and serointensity are associated with hippocampal volume and verbal memory in schizophrenia and bipolar disorder.
... virus type 1 and mouse hepatitis virus, spread along different neural pathways from the main olfactory ...of bipolar disorder: a meta-analysis of neuropsychological deficits in euthymic patients and ...
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Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.
... which are the major L-type alpha subunits found in the brain and their specific association with BD suggests a value to designing calcium channel antagonists that are selective for these subunits. Magnetic ...
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Reconsideration of bipolar disorder as a developmental disorder: importance of the time of onset.
... in bipolar disorder. Bipolar Disord 10, ...in bipolar affective disorder in 70 European families ascertained through a bipolar type I early-onset proband: ...
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Selves Impairment in Bipolar Disorder through Self-Concept Clarity, Self-Defining Memories and Self-Esteem
... 0,01). Bipolar patients showed significant lower scores of the clarity of the self-concept and of its stability and and of self-esteem than healthy subjects (t(32) = - 4,74, p < 0,01; t(32) = - 6,87, p < ...
1
Prevalence of diabetes and the metabolic syndrome in a sample of patients with bipolar disorder.
... schizoaffective disorder (12), the prevalence of the metabolic syndrome appears lower in the bipolar patient ...in bipolar patients as in schizophrenia patients (18), as was the presence of a family ...
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Association of polygenic score for major depression with response to lithium in patients with bipolar disorder
... thresholds. Bipolar patients with a low polygenic load for major depression were more likely to respond well to lithium, compared to patients with high polygenic load, [lowest vs highest PGS quartiles: multi- ...
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