Oxidative stress as marker of piglet health at weaning

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Oxidative stress as marker of piglet health at weaning

Arnaud Buchet, Elodie Merlot, Catherine Belloc

To cite this version:

Arnaud Buchet, Elodie Merlot, Catherine Belloc. Oxidative stress as marker of piglet health at weaning. 9. European Symposium of Porcine Health Management (ESPHM 2017), May 2017, Prague, Czech Republic. Czech-In, 2017, 9th European Symposium of Porcine Health Management (ESPHM).

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9

EUROPEAN SYMPOSIUM OF PORCINE HEALTH MANAGEMENT, 3 – 5 MAY 2017, PRAGUE 168

Poster session

WEL-034 - OXIDATIVE STRESS AS INDICATOR OF PIGLET HEALTH AT WEANING

A. Buchet

, E. Merlot

, C. Belloc

1

INRA AGROCAMPUS, UMR PEGASE, Saint Gilles, France

2

INRA ONIRIS, UMR BIOEPAR, Nantes, France

3

COOPERL ARC ATLANTIQUE, Lamballe, France

Weaning is a source of social, nutritional and environmental changes for piglets, that challenge its health. This study aims to assess the opportunity

to use plasma hydroperoxide (dROM) concentration and antioxidant capacity (BAP), two indicators of oxidative status, as indicator of piglet health

in the context of weaning. In order to dissociate effects of age and management conditions on the evolution of oxidative status around weaning, a study

was carried out, where piglets were followed from 12 to 147 days of age, and weaned at 21 or 28 days of age in optimal (OC) or deteriorated (DC)

conditions (n=16 per group). Oxidative products (dROM), antioxidant capacity (BAP), vitamin E and A were measured in plasma. DC piglets had lower

ADG (P<0.001) and more diarrhea (P<0.01) between 0 and 19 days after weaning compared to OC piglets. Oxidative stress index (OSI, dROM/BAP)

increased for DC but not OC piglets after weaning (P<0.01) due to increased dROM (P=0.05) and decreased BAP (P<0.05). Piglets which exhibited

diarrhea between 0 and 19 days after weaning had higher OSI (P<0.001) and dROM (P<0.01) 12 days after weaning. The concentrations of vitamin

E and A dropped after weaning (P<0.001). Present data indicate that oxidative stress index can be affected by sub-optimal weaning conditions such

as deteriorated management conditions and exhibition of diarrhea. Therefore, oxidative stress index seems to be a relevant candidate as an indicator

of piglet health in the context of weaning.