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Submitted on 4 Jun 2020
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Infant milk formulas: effect of heat treatments on the protein physicochemical properties and the nutritional
quality
Amira Halabi
To cite this version:
Amira Halabi. Infant milk formulas: effect of heat treatments on the protein physicochemical proper- ties and the nutritional quality. STLOpendays, Institut National de Recherche Agronomique (INRA).
UMR UMR INRA / AgroCampus Rennes : Science et Technologie du Lait et de l’?uf (1253)., Mar 2019, Rennes, France. �hal-02098685�
Yves LE LOIR - STLO
STLOpen Days 19-21 March 2019
Welcome
Infant milk formulas:
Effect of heat treatment on the protein
physicochemical properties and the nutritional quality
Amira Halabi – ISF/BN Teams
Interaction-Structure-Functionalities / Bioactivity and nutrition
STLOpen Days
19-21 March 2019 2
Socio-economic and scientific contexts
Percentage of infants 0–5 months of age exclusively breastfed
UNICEF global databases, 2018
Needs Consequences
Digestibility ? Protein structural
modifications Extend shelf-life
Microbiological safety
Heat treatments of infant milk formulas
Adapted from Chatterton et al. 2013
Protein composition of human milk, commercial infant milk formulas and
bovine milk
Whey proteins
STLOpen Days
Strategy
3
What are the impacts of heat treatment on the structure and digestion kinetic of proteins of infant milk formulas mimicking the protein profile of human milk ?
Heat treatment
Temperature range 67.5°C-80°C
Infant milk formulas
Three formulas at 1.3% and 5.5%
of proteins
Formula 1 CN:WP 40:60
Without modification
Formula 2 CN:WP 40:60 LF quantity closes to
that of human milk
Formula 3 CN:WP 40:60
LF and α-LA quantities close to those of human milk
CN: caseins WP: whey proteins
LF: lactoferrin α-LA: α-lactalbumin
Characterization of heat- induced aggregates
Protein interaction – Size - Shape
Kinetic of individual whey protein denaturation
In vitro protein digestion kinetic
Protein hydrolysis – Peptide release - Bioaccessibility
THANK YOU FOR YOUR ATTENTION
MERCI
Please visit http://www.rennes.inra.fr/stlo_eng
STLOpen Days 19-21 March 2019
POSTER 9
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