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Stromal cell contribution to human follicular lymphoma pathogenesis.

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Academic year: 2021

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FIGURE 1 | Follicular lymphoma pathogenesis. The first step of follicular lymphoma (FL) development occurs in the bone marrow as a mistake in V(D)J rearrangement and leads to the ectopic expression of the antiapoptotic protein bcl2
FIGURE 2 | Follicular lymphoma cell niche. (A) Stromal cells recruit and support directly the growth of FL B cells through a combination of adhesion molecules, chemokines, and cytokines

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