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In vivo Efficacy of a Dry Powder Formulation of Ciprofloxacin-Copper Complex in a Chronic Lung Infection Model of Bioluminescent Pseudomonas aeruginosa

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Academic year: 2021

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Figure  2:  Characterization  of  spray  dried  CIP-Cu  and  jet  milled  CIP-HCl  powders
Figure 3: Size distribution of agar beads dispersed in PBS. Size distribution of blank beads  was  determined  by  laser  diffraction  using  the  Sympatec  HELOS-R  equipped  with  a  Cuvette module
Figure  4:  Time-luminescence  curves  obtained  from  bioluminescent  P.  aeruginosa-loaded  beads
Figure  5:  In  vivo  chronic  lung  infection  model.  Sprague-Dawley  rats  were  inoculated  intratracheally  with  various  ratios  of  luminescent  P
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