Short-term consequences of F508del-CFTR thermal instability on CFTR-dependent transepithelial currents in human airway epithelial cells

Genetic depletion of SQSTM1, transgene-enforced BECN1 overexpression, or addition of autophagy-stimulatory pro- teostasis regulators, such as cystamine (or its reduced form

The objective of this study is to show the toxicological effects of ultrafine particles with an important organic compounds content on Beas-2B model and by using an

Cystic fibrosis transmembrane conductance regulator F508del and KO rats were generated by delivering simultaneously, into one-cell stage zygotes, specific single-guide RNA

Porcine precision-cut lung slices (PCLS) were used to analyze the effect of the ciliary activity on infection of airway epithelial cells by influenza viruses.. Treatment of slices

LES TERRASSES ROY Présentation publique - Plans finaux Schéma de drainage. 6

C407 alone or in combination with the F508del‑CFTR corrector VX‑809, increased CFTR activity in cell lines but not in primary respiratory cells carrying the F508del mutation..

The beneficial effects of the (n-3) LC-PUFA diet in CftrF508 mice after LPS challenge that we observed are the decrease in lung metaplasia and modulation of

In an effort to directly demonstrate that airway protease mediated virus entry enhancement is due to the presence of cleavage site on the SARS spike glycoprotein, 16HBE cells