Pyrethroids differentially alter voltage-gated sodium channels from the honeybee central olfactory neurons

1. Molecular structure and organization of neuronal Nav channels. Nav channel neuronal distribution: not so simple!. How do Nav channels cluster at the AIS and the node of

The proper targeting and concentration of Nav channels at the axon initial segment (AIS) and at the nodes of Ranvier are therefore vital for neuronal function.. In AIS and nodes,

We used 3794 variants in the Genome Aggregation Database (gnomAD) (Karczewski et al., 2019) as variants with inferred neutral effects (see Table S2) during training of

In order to take into account the effects of waves in the mo- mentum equations, some quantities provided by wave mod- els are required: period, significant wave height,

Whereas a pronounced tail current was induced by tetramethrin or permethrin after membrane repolarization in honeybee ORNs, the peak amplitude of the sodium current during a single

Here we present a study in which electrophysiology and a Markovian multi-state modelling of the voltage-gated sodium channel were used to measure the susceptibility of the

The aim of this review is to describe the current knowledge on the functional expression of voltage-gated sodium channels and their biological roles in different cancers such as

The activity of Na V 1.6 channels in the plasma membrane of cervical cancer cells was confirmed using the Na V 1.6-specific toxin Cn2 (1 µ M) which blocked ∼ 50% of the sodium