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Cell Death Pathways in Photodynamic Therapy of Cancer

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Academic year: 2021

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Figure  1.  Schematic  illustration  of  the  mechanism  of  Photodynamic  therapy  (PDT)
Figure  2.  Jablonski  diagram.  Ground  state  PS  absorbs  a  photon  of  correct  wavelength  to  excite its electron to first excited singlet state that may (in addition to losing energy by heat  or fluorescence emission) undergo intersystem crossing t
Table 1. Major cell death mechanism activated by Photodynamic therapy (PDT).
Figure 4. Cell death pathways in PDT. The mode of cell death observed after PDT to some  extent depends on the intracellular localization of the PS and PDT related damage to that  organelle

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