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The value of questionnaire and diary in 2020 following the new ICCS standardization papers in treatment naïve patients

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THE VALUE OF QUESTIONNAIRE AND DIARY IN 2020 FOLLOWING THE NEW ICCS

STANDARDIZATION PAPERS IN TREATMENT NAÏVE PATIENTS

S. Karamaria, N. Ranguelov, P. Hansen, V. De Boe, P. Verleyen, J. Vande Walle, L. Dossche, A.

Bael

Dr. Frederic

Paulsen Chair

(2)

MATERIALS AND METHODS

̶ Prospective, multicentre study

̶ Treatment naive

̶ 5 – 16 years old

̶ 7 Belgian Hospitals

‒ CMT as recommended by ICCS

‒ ICCS definitions for MNE/NMNE (old

and new)

(3)

RESULTS

̶ 109 children

̶ 19 lost to follow-up

̶ mean age 7,73 years (±1,98)

̶ 62 boys (68,9%) and 27 girls (30%)

̶ 26 children (29%) >9 years old

̶ 68 children (75, 6%) included at a non-University center

Dr. Frederic

Paulsen Chair

The value of questionnaire and diary in 2020 following the

(4)

RESULTS: DIAGNOSIS

Old definition New definition Physician (patient file)

MNE NMNE MNE NMNE MNE NMNE

CMT 45(50%) 45(50%) 15(17%) 75(83%) 18(20%) 72(80%) diary 66(73%) 24(27%) 16(18%) 74(82%) 31(34%) 59(65%)

MNE/MNE (N=43) NMNE/NMNE 48%

(N=22) 24%

changed diagnosis

(N=25) 28%

MNE/MNE (N=6)

7%

NMNE/NMNE (N=19)

changed 21%

diagnosis (N=65)

72%

(5)

RESULTS: CMT VS DIARY

̶ Agreement:

• Urgency: fair (κ=0,219)

• Daytime incontinence: moderate (κ=0,432)

• Abnormal voiding frequency: no agreement (κ=-0,057)

̶ Correlation:

• MNE: strong (rs = 0,612, p =0,001)

• NMNE: weak (rs = 0,127, p =0,248)

Kwak et al 2007

Surendran et al 2016

Dr. Frederic

Paulsen Chair

The value of questionnaire and diary in 2020 following the

(6)

RESULTS: LUTS

0%

50%

100%

ID (diary)

ID (CMT)

History of ID after 5yo (CMT)

frequency ≤3 or

≥8/day (diary) frequency

≤3 or ≥8/day (CMT) urge (diary)

Urge (CMT) Push to

urinate (CMT) Interrupted

stream (CMT) MVV <65% EBC

AVV <65% EBC

MNE/MNE NMNE/NMNE mixed diagnosis

0%

50%

100%

ID (diary)

ID (CMT)

History of ID after 5yo (CMT)

frequency ≤3 or

≥8/day (diary) frequency

≤3 or ≥8/day (CMT) urge (diary)

Urge (CMT) Push to

urinate (CMT) Interrupted

stream (CMT) MVV <65% EBC

AVV <65% EBC

MNE/MNE NMNE/NMNE mixed diagnosis

ICCS old definition ICCS new definition

(7)

RESULTS: VOIDED VOLUMES

Dr. Frederic

Paulsen Chair

The value of questionnaire and diary in 2020 following the

(8)

CONCLUSIONS

̶ MNE: smaller prevalence based on new definitions

̶ CMT inconsistent with diary: use both methods

̶ Prevalence of MVV and AVV <65% of EBC did not

differ between MNE vs NMNE: no predictive value

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