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Enabling p articipatory Evolution health care and

development

APOC is no longer

just

a static programme of activity to adminrster a single drug to control a

srngle disease.

It

is a large-scale, comprehensive, particlpatory health and development initrative to improve the qualrty ol

lile

for hundreds

of mlllions

of the

worlds

poorest people, most of whom live

in

conditions that

would

not be acceptable an).where else

in

the worid.

Over the past 35 years, over US$ 3

billion

has been invested to tackle Onchocerciasis, mostly

in

Afnca, where some 90o/o of the disease burden prevails.

In Africa, control was rnitrally based on aerial sprayrng of

larlrcide

under the Onchocerciasis Control Programme rn West Africa (OCP) but,

following

the advent of the drug ivermectin, control has been based almost solely on mass administration

ol

this single drug, which has been donated free

lor

as long as needed.

APOC, through rts trademark Community- Directed Treatment

with

rvermettin (CDTI) system, puts people at the centre of Prlmary Health Care (PHC) by creating a comprehensive, integrated, adaptable and sustainable health serwice delivery mechanism

which

functions well in Afncas unique environmental and social conditions. APOC encompasses heaith and welfare promotion, dlsease prevention and delivery of curatlve serrices and products,

while

also

buildlng

capacity for equitable and proactive leadership and long-term sustarnability

in

the health sector

-

on a natlonal and regional basis.

and Progress indicators

Operatrng on an unprecedented scale, APOC extends over

I3.45 million

km2 an area 1.5 trmes larger than the USA and covers a total population of > 500

mlllion, including

some of the

worlds

poorest people. Most live

in

remote rural locations

wlth little

or no access to health semces,

with

half of the oncho- cerciasis endemic target communlties

liung

below the poverty line.

Created

in

1995, APOC u.i11:

.

establish sustainable community-managed treatment for 90

mrllion

people annually, protecting

an'at-risk'

population

of

120

million;

.

alleviate unbearable itching and elimrnate disfiguring skin disease, prevent ocuiar damage and 43,000 cases o[ blindness annually;

.

cumulatively create mrlhons oi years of addrtional productive

work

and greatly boost staple lood production;

ffi

Africa: true scale of APOC's task

(3)

.

facilitate creatlon of national capacity and empower affected communrties to address their critical health issues;

.

protect investments

in

onchocerciasis control.

- 1996 -

Operations begin

wlth

41.8

million

people inlected, 385,000 bhnd and 29.7

million

cases of severe

itching

and onchodermatitis.

-1997 -

Extensive research proves CDTI "feasible (technically,, financially and enl,rronmentally), effective and sustainable." Affected communrties are empowered to help drrect programme activities (when, where and how to distribute tverrnectin).

- lggg/2ooo -

lntegrated intervention delivery ("additional interventions" or "Add-ons") begins,

including

Vitamin-A supplements, MDA agarnst

Lymphatic filanasis (LF) 6J schistosomiasis;

and eye-care services, to impror.,e overall health and reduce

morbidity lrom

a range of diseases.

-

2OO5

-

.

20ok reduction

in

noduies.

.

Severe

itching

reduced

by

54ok.

.

Prevalence of bhndness reduced by 33 o/o .

.

CDTI results

in

US$ 7 per DALY averted.

- 2006 -

.

YAOUNDE DECIARATION of Ministers of Health of APOC member states.

. >

120 n.rillion

still

at risk.

.

Addrtronal US$ 46.5

million

requlred

lrom

donors.

.

37

milhon

inlected people

did

not develop skin diseirse.

.

Prevalence of severe skin lesions haived

-

2OO7

-

.

APOC programme extended to 2015 and broadened to

cover,l

ex-OCP countries.

.

I0 .7 4

milhon

benefitting from integrated delivery o[ PHC interventions.

.

CDT1 is seen as a 'best practice" to emulate

in

other health programmes.

.

Integrated deiivery: doubles coverage

with

treated bednets; Communrty-based treat- ment of children

wrth

fever rises from 47 o/o

lo

77 o/o .

itamin-A dlstribution

nses from 81o/o

to 90 o/o; leads to reduction

ln

prevalence

ol

LF

in

some countries.

.

Ivermectin coverage rises where integration rs used (up

to

73.7 %).

-

2o,c,8

-

.

16.2

million

cases o[ infection averted.

.

Itching prevalence reduced by 68%

(8.9

million

cases averted).

.

5.8

million

DALYs averted.

.

25.7

million

people inlected ln APOC states 64.26

million

ivermectin treatments approved rn APOC countries plus 14.97

million

for ex-OCP nations.

Cumulative >700

million

ivermer'tin treat- ments approved (1998-2008).

1 17,000 communities engaged.

OUAGADOUGOU DECIARATION ON PHC AND HEALTH SYSTEMS INAFRICA.

Co-lmplementation of

multiple

health interventions usrng CDTI network covers 37.5

million

people

in

11 countries.

98 % of aliocated budget disbursed.

I

(4)

(lurrent Progress (zoo9)

Er trle

n.r' llr.rl

n

t'nncttnl

Iisr'

(ilr]

itr'trLiil]\' clrnrir.rtL ( )nclrot cr cirrsi:.

itr I I

nrillron

ir.()|lc

l)(

llq

lre rltr'(1.

Ll0 I

)+ rrrnmrLlnitia: cngrr{ctl.

Sltl.t)r)rl

D,\l

\':

lrcrnS

rtrtrtrtl

rrnrtrr.illr

rill

il r'L):1 o1 t

'S!

l- r.rt h l.

I-l

r'ilnllnt t0:l - [ :s l)

il-lrnnLttrl]r , .1

jl

t r'.rin

irS

! LLn.lLulii irrtr,,rl rtt ecl It,r'

,,,,it., ,l',','l 'r''l .'tt

L't-

\1ittirrtLtnr the tliPilli11' t;irqct

rllsctl

1tr S(l'l , -

J'lr trl

ptr

jri

ts tr,tlLLrtLr-tl rlce nrctl :r-rstirinrrble

,r

lr.lli1n{

:.rti:l.rrIor r' llti)gl(-\s.

irtILtl

11,.,,,,, 1,,{ ( rl (rrLlror'c r.r i;tsi s rtl t rtost

,

irntPlt'ltrl

rrr I !) tLrLrntIrt's '- I S 00rl

( llll

I r':rint'rl \)r

lctrrlinl(l

l8.r)t)s I

l,'.ilrh

\\t,r'1...r': i I

I\\'r

trrLineti

''t

t( lt

tittutl

-otrrl

o1 L +S 0(l[-]

(.1)l):

+ (r l.t)Ot)

II\\

!

tr|!)\\

ir.rtL

it lI.lI|atl

:inr

c

1t)\)t)

- ril

nrilrr,rrlar-lerr'l

:trrll

tr.rirrctl.

|.

:5 ] ll

rrttlltott clr'rotccl ttr t'trte

('I)fl

lt. tn LLte:

ilrr

t)

\lt'nrh-r'\t,tti'5)

t \5 I ,\

nrrlirt n

\\oltlr

()1

r.tIitirl

.rlLltPnt('nt l.t Lrt iclr'tl t(r r r)turt r-ir's

. (

Lr-inrIlcntrrrterl

\ll).\ lirt I

tli:c:r:t's () )alilLilt. jn r !oLLItlt-iaS.

. I l9 brlir,,l

rr Crr.lt'r.Lrn ttrlrlct:

tlonlrtirl

L(

.\l'()(

i

lrlr); r[)0s]

Estimated 90

million

being treated annually via sustainable CDTI.

120

million

protected.

Prevention

of

15

million

DALYs.

680/o

reduction

in blindness.

Severe

itching

(among

farming

and

fishing populations)

reduced

to

1o/o.

Millions

of tonnes of

additional

basic

food

and commercial crops produced.

Cost per

treated

person drops

to

USS 0.2.

Miliions of years of

productive work

added

to

national economies.

Criteria

for stopping

of

treatment

established in member countries.

Shrinking

the

onchocerciasis map in Africa.

Economic Rate of Return

=

17 o/o.

Additional>

1

million

experienced CDD, HW & managerial staff engaged in health system activities.

Enhanced

development

of

epidemiolo- gicalknowledge.

lntegration

of

community-managed

multidisease

intervention

and

prevention.

Provision of specialized and

adaptable equipment,

skills,

technologies

and systems (national & regional).

Novel partnerships developed

for

health improvements.

Adaptation

of

control intervention to

adjust

to impact

of Climate Change.

Positive

contribution

towards achieving:

- MILLENNIUM DEVELOPMENT GOALS - AFRICA'S GREEN REVOLUTION

-

VISION-2020 goal of

elimination

of

allforms

of avoidable blindness.

27 years of healthy life gained

for each USS 1 invested

(5)

Future needs

Advocacy to regional bodies

&

strategic communication to maintain political commitment

in

Member states.

Creation of capacity at perlpheral health facilities and

in

communrties.

Mobilise

&

sustain funding and investment at all leveis and

in

all aspects.

Maintain annual and long-term compliance

with

treatment.

Integrated delivery via the CDTI process

of

appropriate, proven health interventions.

More effective reporting and health metrics gathenng.

Continued systematic application of RAPLOA and other mapping.

Monitoring

and surveillance of control programmes (and

ior

drug resistance. impact of Climate Change, etc.).

Continuing search for a macrofilaricide Improved disease awareness and community involvement

in

control activities.

An APOC challenge:

Climate Change

Onchocerciasis is intimately

linked with

rainfall patterns, river basins and agriculture, all

of which

are forecast to be significantly affected

by

Climate Change. APOC's target popuiations live

in

remote, rural locations and depend on subsistence farming for their livelihoods. These communities are especiaiiy l'ulnerable because they depend entirely on rainfed agriculture

but

have

little

human, physical and capltal resources as well as very basic infrastructure, generally existing i.n poor health

with

poor food security and widespread

malnutrition.

I

ocPcountries

I

epoc Member

states

(6)

"The progress that has been made in combrsting River Blindness (Onchocerciasis) represents ane of the most trrumphant public health

campaigns ever waged tn the developing world."

(uNESco)

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