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PET/MR Imaging: Clinical Applications

TORIGIAN, Drew A, et al.

TORIGIAN, Drew A, et al . PET/MR Imaging: Clinical Applications. PET Clinics , 2016, vol. 11, no. 4, p. xi-xii

DOI : 10.1016/j.cpet.2016.07.001 PMID : 27593253

Available at:

http://archive-ouverte.unige.ch/unige:90677

Disclaimer: layout of this document may differ from the published version.

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Preface

PET/MR Imaging: Clinical Applications

Drew A. Torigian, MD, MA, FSAR

Andreas Kjær, MD, PhD, DMSc

Habib Zaidi, PhD, PD Abass Alavi, MD, MD (Hon), PhD (Hon), DSc (Hon) Editors

Clinical PET/MRI systems have recently become commercially available, offering many advantages compared with PET/CT, leading to much enthu- siasm in the medical community at large. Such ad- vantages include a reduced exposure to ionizing radiation, superior soft tissue contrast resolution, and the capability to provide functional and multi- parametric imaging data based on advanced MRI techniques (eg, diffusion-weighted imaging, dy- namic perfusion imaging, magnetic resonance spectroscopy, or magnetic resonance elastography) that are complementary with the molecular data provided by PET. However, the higher costs, the slower scanning times with associated lower patient throughputs, the increased complexity, and the rela- tive lack of diagnostic benefit of PET/MRI in some clinical applications relative to either PET/CT or inde- pendently acquired PET and MRI have somewhat dampened this initial excitement. Yet, it is likely that PET/MRI will still play an important future role in the clinical diagnostic imaging assessment of certain groups of patients with certain disease condi- tions, although such niche applications are still being defined. Additional technical challenges hampering quantitative imaging including the lack of consensus on reliable and accurate MRI-guided attenuation correction techniques are being addressed by active research groups in the scientific literature.

Therefore, in this issue ofPET Clinics, we have enclosed a series of review articles that focus on clinical PET/MRI. In particular, clinical applica- tions of PET/MRI for the evaluation of malignancy (including lymphoma, head and neck cancer, breast

cancer, lung cancer, gastrointestinal tract cancers, and gynecologic cancers), brain disease, musculo- skeletal disorders, and cardiovascular disease are discussed. We also briefly provide an article regarding our future perspectives on clinical PET/MRI in the oncologic setting. This issue nicely complements the April 2016 issue, “PET/MRI:

Advances in Instrumentation and Quantitative Pro- cedures,” (Vol. 11, No. 2) edited by Dr Habib Zaidi.

We would like to thank all of the authors who contributed these articles, and we hope that the readers of these articles will learn much and apply what is learned to the future clinical practice of PET/MRI for the benefit of their patients.

Drew A. Torigian, MD, MA, FSAR Department of Radiology Hospital of the University of Pennsylvania 3400 Spruce Street Philadelphia, PA 19104, USA Andreas Kjær, MD, PhD, DMSc Department of Clinical Physiology Nuclear Medicine & PET and Cluster for Molecular Imaging Rigshospitalet and University of Copenhagen KF-4012, Blegdamsvej 9 2100 Copenhagen, Denmark Habib Zaidi, PhD, PD Division of Nuclear Medicine & Molecular Imaging Geneva University Hospital CH-1211 Geneva, Switzerland

PET Clin 11 (2016) xi–xii

http://dx.doi.org/10.1016/j.cpet.2016.07.001

1556-8598/16/Ó2016 Published by Elsevier Inc.

pet.theclinics.com

PET/MRI: Clinical Applications

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Abass Alavi, MD, MD (Hon), PhD (Hon), DSc (Hon) Department of Radiology Hospital of the University of Pennsylvania 3400 Spruce Street Philadelphia, PA 19104, USA

E-mail addresses:

Drew.Torigian@uphs.upenn.edu(D.A. Torigian) akjaer@sund.ku.dk(A. Kjær) habib.zaidi@hcuge.ch(H. Zaidi) abass.alavi@uphs.upenn.edu(A. Alavi) Preface

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