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Chapter 1 Genome-scale metabolic modeling of microorganisms and the cocoa bean fermentation process

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Academic year: 2021

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Contents

Introduction 1

List of abbreviations 2

Chapter 1 Genome-scale metabolic modeling of microorganisms and the cocoa bean fermentation process

3

Chapter 2 Aims and objectives 33

Chapter 3 Genome-scale metabolic reconstruction of Acetobacter pasteurianus 386B, a candidate functional starter culture for cocoa bean fermentation

35

Chapter 4 Application of comparative genomics of Acetobacter species facilitates genome-scale metabolic reconstruction of

Acetobacter ghanensis LMG 23848

T

and Acetobacter senegalensis 108B

57

Chapter 5 Genome-scale metabolic modeling of Acetobacter

pasteurianus 386B reveals its metabolic adaptation to cocoa fermentation conditions

73

Chapter 6 Dynamic modeling of Acetobacter pasteurianus 386B and Acetobacter ghanensis LMG 23848

T

, two candidate functional starter cultures for cocoa bean fermentation processes

91

Chapter 7 Genome-scale metabolic modeling of the candidate

functional starter cultures Lactobacillus fermentum 222 and Lactobacillus plantarum 80 for cocoa bean fermentation processes

109

Chapter 8 General conclusions 129

References 137

Summary 167

Samenvatting 169

Résumé 171

Curriculum vitae 173

Annexes 175

Références

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