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Facilitating efficient knowledge management and discovery in the Agronomic Sciences

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Facilitating efficient knowledge

management and discovery in the

Agronomic Sciences

Aravind Venkatesan1, Pierre Larmande1,2, Clement Jonquent3, Manuel Ruiz1,4 and Patrick Valduriez1,3,5

1 – Institut de biologie Computationelle (IBC), Montpellier, France 2 – IRD, UMR DIADE, Montpellier, France

3 – LIRMM, Montpellier, France 4 – CIRAD, Montpellier, France

5 – INRIA, Montpellier, France

Background

Agronomic Linked Data (AgroLD)

The advancement of empirical and information technologies in the recent years have drastically

increased the amount of data in fields of Life Sciences, and Agronomic Sciences. To understand the complexity of a given system it is important to link (integrate) diverse datasets. A promising solution towards data integration challenges is offered by the Semantic Web technologies1. The Semantic Web was proposed, to remedy the fragmentation of all potentially useful information on the web. Currently, the bio-medical domain has accepted the Semantic Web technologies as a means to manage (integrate) knowledge. Although we are witnessing an increased usage of ontologies within the

Agronomic Sciences, the data in this domain is highly distributed in nature. Utilizing these data resources more effectively and taking advantage of associated cross-disciplinary research opportunities poses a major challenge to both domain experts and information technologists.

Aim

• Build an RDF knowledge base to house data sources pertain to

plant data.

• Enable answering of complex domain relevant questions that were unapproachable using

traditional methods.

Current status

• A Plant specific instance of BioPortal for managing and browsing ontologies has been set-up.

• Data integration pipeline for modeling the various domain specific

resources into RDF (work in progress).

• AgroLD is being developed in stages:

– Stage 1: Data (molecular level) pertaining to A.thaliana and Oryza

sps. exposed as RDF.

– Stage 2: The knowledge base will be expanded to incorporate other important species such as Wheat.

AgroLD

Outlook to the future

• Integration of more data sources (e.g.: PPI, germplasm, and gene markers).

• Collaboration with biologists and bioinformaticians to provide proof of concept.

– Pluggable with workflow systems e.g: Galaxy2 and

VirtualPlants3.

– Work with plant biologists to construct complex queries for hypothesis generation and validation (wet lab).

We are open to discussions and collaborations. Feel free to get in touch: Dr. Aravind Venkatesan: aravind.venkatesan@lirmm.fr

Dr. Pierre Larmande: peirre.larmande@ird.fr

1 Berners-Lee, T. and Hendler, J. (2001). 'Publishing on

the semantic web'. Nature, 410, 1023-4.

2 Giardine B, et al., Galaxy: a

platform for interactive large-scale genome analysis. Genome Res 2005,

15:1451-1455.

3Katari MS, et al. VirtualPlant: A software platform to

support Systems Biology research. Plant Physiol. 2010;152(2):500-515.

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