• Aucun résultat trouvé

Sex determination diversity in fish

N/A
N/A
Protected

Academic year: 2021

Partager "Sex determination diversity in fish"

Copied!
3
0
0

Texte intégral

(1)

HAL Id: hal-02737595

https://hal.inrae.fr/hal-02737595

Submitted on 2 Jun 2020

HAL is a multi-disciplinary open access archive for the deposit and dissemination of sci- entific research documents, whether they are pub- lished or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers.

L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou étrangers, des laboratoires publics ou privés.

Sex determination diversity in fish

M. Adolfi, Anabel Martinez-Bengochea, A.S. Roco, V. Kottler, - Du, K., S.

Kneitz, Qiaowei Pan, Romain Feron, Elodie Jouanno, Ming Wen, et al.

To cite this version:

M. Adolfi, Anabel Martinez-Bengochea, A.S. Roco, V. Kottler, - Du, K., et al.. Sex determination diversity in fish. 11. International Symposium on Reproductive Physiology of Fish, Instituto Nacional de Pesquisas da Amazônia (INPA). Manaus, BRA., Jun 2018, Manaus, Brazil. 251 p. �hal-02737595�

(2)

- 22 -

LECTURE 1

SEX DETERMINATION DIVERSITY IN FISH

Adolfi, M.

(1)

, Martinez-Bengochea, A.

(1),(7)

, Roco, A. S.

(1)

, Kottler, V.

(1)

, Du, K.

(1)

, Kneitz, S.

(1)

, Pan, Q.

(2)

, Feron, R.

(2)

, Jouanno, E.

(2)

, Wen, M.

(2)

, Imarazene, B.

(2)

, Anderson, J.

(2)

, Wang, Z.

(1)

, Wilson, C.

(3)

, McCluskey, B.

(3)

, Amores, A.

(3)

, Desvigne, T.

(3)

, Klopp, C.

(4)

, Lopez-Roques, C.

(5)

, Chabrol, O.

(5)

, Donnadieu, C.

(5)

, Parrinello, H.

(6)

, Journot, L.

(6)

, Herpin, A.

(2)

, Postlethwait, J.

(3)

, Guiguen, Y.

(2)

, Schartl, M.

(1)

.

(1)

University of Wuerzburg, Physiological Chemistry, Biocenter, 97074 Wuerzburg, Germany.

(2)

INRA, Fish Physiology and Genomics laboratory, 35042 Rennes, France.

(3)

University of Oregon, Institute of Neuroscience, Eugene OR 97403, USA.

(4)

INRA, SIGENAE, UR875, INRA Auzeville, 31326 Castanet-Tolosan, France.

(5)

INRA, GetPlage INRA Auzeville, 31326 Castanet-Tolosan, France.

(6)

MGX (Montpellier Genomix), 34094 Montpellier Cedex 05, France.

(7)

Reproductive and Molecular Biology Group, Department of Morphology, Institute of Bioscience of Botucatu, São Paulo State University, Botucatu, São Paulo, Brazil. e-mail: phch1@biozentrum.uni-wuerzburg.de

Fish show the greatest plasticity of sex determination (SD) mechanisms amongst vertebrates.

In the case of genetic SD this is linked to a similarly high variability of sex chromosome differentiation. While in a handful of species with genetic SD the master SD genes have been identified, their molecular function in directing the development of the bipotential gonad primordium towards testis or ovary is unclear in many cases or incompletely known in the others. To obtain a better understanding of the biological meaning of this diversity we need a deeper understanding of the molecular basis of SD mechanisms and the structure and genetic organization of sex chromosomes across a broad diversity of actinopterygian fish. To identify primary SD genes we used high throughput RAD-tag marker mapping in >40 species as well as transcriptomics, Pool-Seq and genome sequencing to identify sex-specific chromosomal regions and candidate SD genes. This led to the identification of sex-specific markers, allowing to delineate the extent of recombination suppression, which turned out to be highly variable between species. We identified several species with clear cut XX/XY or ZZ/ZW monofactorial systems but also species with more complex sex-determination systems including species with a mix of GSD and ESD and species with potential polygenic systems.

In species with available genomic resources, sex-specific markers could be used to assign

scaffolds to regions that are supposed to contain the primary SD gene. We identified

candidate genes in several species and find that most of them belong to already known factors

of the primary SD regulatory network including candidate genes that have not been found so

far as being SD genes. We also find that many species harbor very poorly differentiated sex-

chromosomes. While the variety of SD genes that can trigger the male or female SD

regulatory network and the differentiation of the gonads is now well established, it is only

emerging that also the whole system downstream of the primary SD factors is subject to

evolutionary change and - like the top SD genes - can vary even between closely related

species. Transcriptome profiling of gonads during male and female development and of

mature ovaries and testes uncovered an unexpected extent of differential gene expressions in

contrast to an obviously striking morphological and physiological conservation of the

reproductive organ system.

(3)

- 1 -

PROGRAM AND

ABSTRACTS

11 ISRF

2018

Références

Documents relatifs

Only alternative processes such as heterogeneous nucleation on EPS and/or microbial cell surfaces or increase of saturation by metabolic activity would otherwise allow

Fructan metabolism in expanding leaves, mature leaf sheaths and mature leaf blades of Lolium perenne: fructan synthesis, fructosyltransferase and invertase activities.. The

The model generates explicit temporal predictions of community-scale data across these three diversity axes (species richness and abundance, population genetic diversity, and trait

To better understand why the different release phases were observed from the investigated caffeine-loaded PLGA microparticles (and why there was a moderate difference in

High grade students recognize the transformation if they recognize the relevant elements of geometric transformation using the process of the function point-to-point, and

The purpose of this article is: (a) to develop reasons linked with society and statistics for a public understanding of statistics, (b) to examine if the concept of civic

Distribution of the spoligotypes of the Spanish Mycobacterium bovis isolates according to prevalence [frequent types (>1%), infrequent types and orphans (singular

We show below that a two-phases algorithm needs a maximum number of evaluations of the problem’s functions and derivatives up to order p ranging from O( 1−2(p+1)/p ) to O(