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Age and albumin D site-binding protein control tissue plasminogen activator levels: neurotoxic impact.

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Academic year: 2021

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Figure 1 Effect of ageing on tPA proteolytic activity and transcription in the CNS and the plasma
Figure 4A and B shows that the ischaemic lesion and the perme- perme-ability of the blood–brain barrier after ischaemic stroke were  sig-nificantly reduced (40%) in WT 15-month-old mice and older, with a profile similar to that observed for tPA mRNA levels
Figure 4 Effect of ageing on ischaemia-induced blood–brain barrier leakage and infarct volumes

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