BIBLIOGRAPHIE
(1997). Breast cancer and hormone replacement therapy: collaborative reanalysis of data from 51 epidemiological studies of 52,705 women with breast cancer and 108,411 women without breast cancer. Collaborative Group on Hormonal Factors in Breast Cancer.
Lancet350, 1047-1059.
Ahmed, M., and Rahman, N. (2006). ATM and breast cancer susceptibility. Oncogene 25, 5906-5911.
Ambros, V. (2001). microRNAs: tiny regulators with great potential. Cell107, 823-826.
Ameisen, J.C., Idziorek, T., Billaut-Mulot, O., Loyens, M., Tissier, J.P., Potentier, A., and Ouaissi, A. (1995). Apoptosis in a unicellular eukaryote (Trypanosoma cruzi):
implications for the evolutionary origin and role of programmed cell death in the control of cell proliferation, differentiation and survival. Cell death and differentiation 2, 285-300.
Bai, R.K., Leal, S.M., Covarrubias, D., Liu, A., and Wong, L.J. (2007). Mitochondrial genetic background modifies breast cancer risk. Cancer research67, 4687-4694.
Balint, E.E., and Vousden, K.H. (2001). Activation and activities of the p53 tumour suppressor protein. British journal of cancer85, 1813-1823.
Barnes, D.E., and Lindahl, T. (2004). Repair and genetic consequences of endogenous DNA base damage in mammalian cells. Annual review of genetics38, 445-476.
Bartel, D.P. (2004). MicroRNAs: genomics, biogenesis, mechanism, and function. Cell116, 281-297.
Berezikov, E., Guryev, V., van de Belt, J., Wienholds, E., Plasterk, R.H., and Cuppen, E.
(2005). Phylogenetic shadowing and computational identification of human microRNA genes. Cell120, 21-24.
Bernstein, L., and Ross, R.K. (1993). Endogenous hormones and breast cancer risk.
Epidemiologic reviews15, 48-65.
Bhoumik, A., Takahashi, S., Breitweiser, W., Shiloh, Y., Jones, N., and Ronai, Z. (2005).
ATM-dependent phosphorylation of ATF2 is required for the DNA damage response.
Molecular cell18, 577-587.
Blackburn, E.H. (1991). Structure and function of telomeres. Nature350, 569-573.
Bohr, V.A., Ottersen, O.P., and Tonjum, T. (2007). Genome instability and DNA repair in brain, ageing and neurological disease. Neuroscience145, 1183-1186.
Boyd, N.F., Dite, G.S., Stone, J., Gunasekara, A., English, D.R., McCredie, M.R., Giles, G.G., Tritchler, D., Chiarelli, A., Yaffe, M.J., et al. (2002). Heritability of mammographic density, a risk factor for breast cancer. The New England journal of medicine347, 886- 894.
Bryan, T.M., Englezou, A., Dalla-Pozza, L., Dunham, M.A., and Reddel, R.R. (1997).
Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nature medicine3, 1271-1274.
Calin, G.A., Dumitru, C.D., Shimizu, M., Bichi, R., Zupo, S., Noch, E., Aldler, H., Rattan, S., Keating, M., Rai, K., et al. (2002). Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America 99, 15524- 15529.
Calin, G.A., Sevignani, C., Dumitru, C.D., Hyslop, T., Noch, E., Yendamuri, S., Shimizu, M., Rattan, S., Bullrich, F., Negrini, M., et al. (2004). Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers.
Proceedings of the National Academy of Sciences of the United States of America101, 2999-3004.
Callahan, R., and Smith, G.H. (2000). MMTV-induced mammary tumorigenesis: gene discovery, progression to malignancy and cellular pathways. Oncogene19, 992-1001.
Carmeliet, P., and Jain, R.K. (2000). Angiogenesis in cancer and other diseases. Nature407,
249-257.
Carrington, J.C., and Ambros, V. (2003). Role of microRNAs in plant and animal development. Science (New York, NY301, 336-338.
Chen, C.L., Weiss, N.S., Newcomb, P., Barlow, W., and White, E. (2002). Hormone replacement therapy in relation to breast cancer. Jama287, 734-741.
Chen, Z., Trotman, L.C., Shaffer, D., Lin, H.K., Dotan, Z.A., Niki, M., Koutcher, J.A., Scher, H.I., Ludwig, T., Gerald, W., et al. (2005). Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature436, 725-730.
Cheng, A.M., Byrom, M.W., Shelton, J., and Ford, L.P. (2005a). Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis. Nucleic acids research33, 1290-1297.
Cheng, L.C., Tavazoie, M., and Doetsch, F. (2005b). Stem cells: from epigenetics to microRNAs. Neuron46, 363-367.
Chin, L., Tam, A., Pomerantz, J., Wong, M., Holash, J., Bardeesy, N., Shen, Q., O'Hagan, R., Pantginis, J., Zhou, H., et al. (1999). Essential role for oncogenic Ras in tumour maintenance. Nature400, 468-472.
Chlebowski, R.T., Hendrix, S.L., Langer, R.D., Stefanick, M.L., Gass, M., Lane, D., Rodabough, R.J., Gilligan, M.A., Cyr, M.G., Thomson, C.A., et al.(2003). Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women's Health Initiative Randomized Trial. Jama 289, 3243-3253.
Cimmino, A., Calin, G.A., Fabbri, M., Iorio, M.V., Ferracin, M., Shimizu, M., Wojcik, S.E., Aqeilan, R.I., Zupo, S., Dono, M., et al.(2005). miR-15 and miR-16 induce apoptosis by targeting BCL2. Proceedings of the National Academy of Sciences of the United States of America102, 13944-13949.
Clemons, M., and Goss, P. (2001). Estrogen and the risk of breast cancer. The New England journal of medicine344, 276-285.
Coffey, R.J., Jr., Meise, K.S., Matsui, Y., Hogan, B.L., Dempsey, P.J., and Halter, S.A. (1994).
Acceleration of mammary neoplasia in transforming growth factor alpha transgenic mice by 7,12-dimethylbenzanthracene. Cancer research54, 1678-1683.
Cohen, P.R., Kohn, S.R., and Kurzrock, R. (1991). Association of sebaceous gland tumors and internal malignancy: the Muir-Torre syndrome. The American journal of medicine90, 606-613.
Colditz, G.A., Egan, K.M., and Stampfer, M.J. (1993). Hormone replacement therapy and risk of breast cancer: results from epidemiologic studies. American journal of obstetrics and gynecology168, 1473-1480.
Colditz, G.A., Stampfer, M.J., Willett, W.C., Hennekens, C.H., Rosner, B., and Speizer, F.E.
(1990). Prospective study of estrogen replacement therapy and risk of breast cancer in postmenopausal women. Jama264, 2648-2653.
Colditz GA, Strampfer MJ, Willett WC, hennekens CH. Prospective study of oral contraceptive use and the risk of breast cancer women. JAMA 1990; 260: 652-6.
Cormier, R.T., Hong, K.H., Halberg, R.B., Hawkins, T.L., Richardson, P., Mulherkar, R., Dove, W.F., and Lander, E.S. (1997). Secretory phospholipase Pla2g2a confers resistance to intestinal tumorigenesis. Nature genetics17, 88-91.
Costa, A., Daidone, M.G., Daprai, L., Villa, R., Cantu, S., Pilotti, S., Mariani, L., Gronchi, A., Henson, J.D., Reddel, R.R., et al. (2006). Telomere maintenance mechanisms in liposarcomas: association with histologic subtypes and disease progression. Cancer research66, 8918-8924.
Cotroneo, M.S., Merry, G.M., Haag, J.D., Lan, H., Shepel, L.A., and Gould, M.N. (2006). The Mcs7 quantitative trait locus is associated with an increased susceptibility to mammary cancer in congenic rats and an allele-specific imbalance. Oncogene25, 5011-5017.
Counter, C.M., Avilion, A.A., LeFeuvre, C.E., Stewart, N.G., Greider, C.W., Harley, C.B., and Bacchetti, S. (1992). Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. The EMBO journal 11, 1921-1929.
Cowland, J.B., Hother, C., and Gronbaek, K. (2007). MicroRNAs and cancer. Apmis 115, 1090-1106.
Cox, A., Dunning, A.M., Garcia-Closas, M., Balasubramanian, S., Reed, M.W., Pooley, K.A., Scollen, S., Baynes, C., Ponder, B.A., Chanock, S., et al. (2007). A common coding variant in CASP8 is associated with breast cancer risk. Nature genetics39, 352-358.
Dahlman, I., Eaves, I.A., Kosoy, R., Morrison, V.A., Heward, J., Gough, S.C., Allahabadia, A., Franklyn, J.A., Tuomilehto, J., Tuomilehto-Wolf, E., et al.(2002). Parameters for reliable results in genetic association studies in common disease. Nature genetics 30, 149-150.
Dameron, K.M., Volpert, O.V., Tainsky, M.A., and Bouck, N. (1994). Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. Science (New York, NY 265, 1582-1584.
De Miglio, M.R., Simile, M.M., Muroni, M.R., Calvisi, D.F., Virdis, P., Asara, G., Frau, M., Bosinco, G.M., Seddaiu, M.A., Daino, L., et al. (2003). Phenotypic reversion of rat neoplastic liver nodules is under genetic control. International journal of cancer105, 70-75.
de Moor, C.H., Meijer, H., and Lissenden, S. (2005). Mechanisms of translational control by the 3' UTR in development and differentiation. Seminars in cell & developmental biology16, 49-58.
Debidda, M., Williams, D.A., and Zheng, Y. (2006). Rac1 GTPase regulates cell genomic stability and senescence. The Journal of biological chemistry281, 38519-38528.
Di Micco, R., Fumagalli, M., and di Fagagna, F. (2007). Breaking news: high-speed race ends in arrest--how oncogenes induce senescence. Trends in cell biology17, 529-536.
Dietrich, W.F., Lander, E.S., Smith, J.S., Moser, A.R., Gould, K.A., Luongo, C., Borenstein, N., and Dove, W. (1993). Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse. Cell75, 631-639.
Dizdaroglu, M. (2005). Base-excision repair of oxidative DNA damage by DNA glycosylases.
Mutation research591, 45-59.
Dunham, M.A., Neumann, A.A., Fasching, C.L., and Reddel, R.R. (2000). Telomere maintenance by recombination in human cells. Nature genetics26, 447-450.
Dunning, W.F., Curtis, M.R., and Segaloff, A. (1953). Strain differences in response to estrone and the induction of mammary gland, adrenal, and bladder cancer in rats. Cancer research13, 147-152.
Easton, D.F., Pooley, K.A., Dunning, A.M., Pharoah, P.D., Thompson, D., Ballinger, D.G., Struewing, J.P., Morrison, J., Field, H., Luben, R., et al. (2007). Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 447, 1087- 1093.
Erkko, H., Xia, B., Nikkila, J., Schleutker, J., Syrjakoski, K., Mannermaa, A., Kallioniemi, A., Pylkas, K., Karppinen, S.M., Rapakko, K., et al. (2007). A recurrent mutation in PALB2 in Finnish cancer families. Nature446, 316-319.
Esteller, M., Silva, J.M., Dominguez, G., Bonilla, F., Matias-Guiu, X., Lerma, E., Bussaglia, E., Prat, J., Harkes, I.C., Repasky, E.A., et al.(2000). Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors. Journal of the National Cancer Institute92, 564-569.
Evans, M.D., Dizdaroglu, M., and Cooke, M.S. (2004). Oxidative DNA damage and disease:
induction, repair and significance. Mutation research567, 1-61.
Felsher, D.W. (2003). Cancer revoked: oncogenes as therapeutic targets. Nat Rev Cancer3, 375-380.
Felsher, D.W., and Bishop, J.M. (1999). Reversible tumorigenesis by MYC in hematopoietic lineages. Molecular cell4, 199-207.
Ferrara, N. (2002). VEGF and the quest for tumour angiogenesis factors. Nat Rev Cancer 2, 795-803.
Feigelson, H.S., and Henderson, B.E. (2001). The epidemiology of breast cancer. In Breast cancer: A clinical Guide Therapy, G. Bonnadona, G.N hortobagyi, and A.M. Gianni, eds. (London: Martin Dunitz LTD)
Fidler, I.J., and Ellis, L.M. (1994). The implications of angiogenesis for the biology and therapy of cancer metastasis. Cell79, 185-188.
Fisher, G.H., Wellen, S.L., Klimstra, D., Lenczowski, J.M., Tichelaar, J.W., Lizak, M.J., Whitsett, J.A., Koretsky, A., and Varmus, H.E. (2001). Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes. Genes & development15, 3249-3262.
Folgueras, A.R., Pendas, A.M., Sanchez, L.M., and Lopez-Otin, C. (2004). Matrix metalloproteinases in cancer: from new functions to improved inhibition strategies.
The International journal of developmental biology48, 411-424.
Friedberg, EF., Walker, G.C. and Siede,W. (1995) DNA repair and Mutagenesis. ASM Press, Washington, DC.
Futreal, P.A., Liu, Q., Shattuck-Eidens, D., Cochran, C., Harshman, K., Tavtigian, S., Bennett, L.M., Haugen-Strano, A., Swensen, J., Miki, Y., et al. (1994). BRCA1 mutations in primary breast and ovarian carcinomas. Science (New York, NY266, 120-122.
Gaudet, M.M., Egan, K.M., Lissowska, J., Newcomb, P.A., Brinton, L.A., Titus-Ernstoff, L., Yeager, M., Chanock, S., Welch, R., Peplonska, B., et al. (2007). Genetic variation in tumor necrosis factor and lymphotoxin-alpha (TNF-LTA) and breast cancer risk.
Human genetics121, 483-490.
Gering, K.M., Marx, J.A., Lennartz, K., Fischer, C., Rajewsky, M.F., and Kindler-Rohrborn, A. (2006). The interaction mode of premalignant Schwann and immune effector cells during chemically induced carcinogenesis in the rat peripheral nervous system is strongly influenced by genetic background. Cancer research66, 4708-4714.
Gibbs, R.A., Weinstock, G.M., Metzker, M.L., Muzny, D.M., Sodergren, E.J., Scherer, S., Scott, G., Steffen, D., Worley, K.C., Burch, P.E., et al.(2004). Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature428, 493-521.
Gould, K.A., Tochacek, M., Schaffer, B.S., Reindl, T.M., Murrin, C.R., Lachel, C.M., VanderWoude, E.A., Pennington, K.L., Flood, L.A., Bynote, K.K., et al. (2004).
Genetic determination of susceptibility to estrogen-induced mammary cancer in the ACI rat: mapping of Emca1 and Emca2 to chromosomes 5 and 18. Genetics 168, 2113-2125.
Gould, M.N. (1986). Inheritance and site of expression of genes controlling susceptibility to mammary cancer in an inbred rat model. Cancer research46, 1199-1202.
Gould, M.N. (1995). Rodent models for the study of etiology, prevention and treatment of breast cancer. Seminars in cancer biology6, 147-152.
Grandori, C., Wu, K.J., Fernandez, P., Ngouenet, C., Grim, J., Clurman, B.E., Moser, M.J., Oshima, J., Russell, D.W., Swisshelm, K., et al. (2003). Werner syndrome protein limits MYC-induced cellular senescence. Genes & development17, 1569-1574.
Greider, C.W. (1998). Telomerase activity, cell proliferation, and cancer. Proceedings of the National Academy of Sciences of the United States of America95, 90-92.
Gudmundsdottir, K., and Ashworth, A. (2006). The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability. Oncogene25, 5864-5874.
Gullino, P.M., Pettigrew, H.M., and Grantham, F.H. (1975). N-nitrosomethylurea as mammary gland carcinogen in rats. Journal of the National Cancer Institute54, 401-414.
Haag, J.D., Newton, M.A., and Gould, M.N. (1992). Mammary carcinoma suppressor and susceptibility genes in the Wistar-Kyoto rat. Carcinogenesis13, 1933-1935.
Haag, J.D., Shepel, L.A., Kolman, B.D., Monson, D.M., Benton, M.E., Watts, K.T., Waller, J.L., Lopez-Guajardo, C.C., Samuelson, D.J., and Gould, M.N. (2003). Congenic rats reveal three independent Copenhagen alleles within the Mcs1 quantitative trait locus that confer resistance to mammary cancer. Cancer research63, 5808-5812.
Hakem, R., de la Pompa, J.L., and Mak, T.W. (1998). Developmental studies of Brca1 and Brca2 knock-out mice. Journal of mammary gland biology and neoplasia3, 431-445.
Haluska, F.G., and Hodi, F.S. (1998). Molecular genetics of familial cutaneous melanoma. J Clin Oncol16, 670-682.
Hanawalt, P.C. (2002). Subpathways of nucleotide excision repair and their regulation.
Oncogene21, 8949-8956.
Harris, S.R., Mehta, R.S., Hartle, D.K., Broderson, J.R., and Bunce, O.R. (1994). Failure of high fat diets to promote mammary cancers in spontaneously hypertensive rats. Cancer letters87, 9-15.
Hatfield, S.D., Shcherbata, H.R., Fischer, K.A., Nakahara, K., Carthew, R.W., and Ruohola- Baker, H. (2005). Stem cell division is regulated by the microRNA pathway. Nature 435, 974-978.
Haugwitz, M., Noegel, A.A., Karakesisoglou, J., and Schleicher, M. (1994). Dictyostelium amoebae that lack G-actin-sequestering profilins show defects in F-actin content, cytokinesis, and development. Cell79, 303-314.
Hayflick, L. (1974). The longevity of cultured human cells. Journal of the American Geriatrics Society22, 1-12.
Hayflick, L. (1997). Mortality and immortality at the cellular level. A review. Biochemistry 62, 1180-1190.
He, H., Jazdzewski, K., Li, W., Liyanarachchi, S., Nagy, R., Volinia, S., Calin, G.A., Liu, C.G., Franssila, K., Suster, S., et al.(2005). The role of microRNA genes in papillary thyroid carcinoma. Proceedings of the National Academy of Sciences of the United States of America102, 19075-19080.
Hedrich, H. (1990) Genetic monitoring of inbred strains of rats (Stuttgart, New York: Gustav Fisher Verkag
Heikkinen, K., Rapakko, K., Karppinen, S.M., Erkko, H., Knuutila, S., Lundan, T., Mannermaa, A., Borresen-Dale, A.L., Borg, A., Barkardottir, R.B., et al. (2006).
RAD50 and NBS1 are breast cancer susceptibility genes associated with genomic instability. Carcinogenesis27, 1593-1599.
Helleday, T., Bryant, H.E., and Schultz, N. (2005). Poly(ADP-ribose) polymerase (PARP-1) in homologous recombination and as a target for cancer therapy. Cell cycle (Georgetown, Tex4, 1176-1178.
Hoeijmakers, J.H.J. (1994) Human nucleotide excision repair syndromes: molecular clues to unexpected intricacies. Eur.J.Cancer, 30, 1912-1921.
Hollstein, M., Rice, K., Greenblatt, M.S., Soussi, T., Fuchs, R., Sorlie, T., Hovig, E., Smith- Sorensen, B., Montesano, R., and Harris, C.C. (1994). Database of p53 gene somatic mutations in human tumors and cell lines. Nucleic acids research22, 3551-3555.
Hsu, L.C., Kennan, W.S., Shepel, L.A., Jacob, H.J., Szpirer, C., Szpirer, J., Lander, E.S., and Gould, M.N. (1994). Genetic identification of Mcs-1, a rat mammary carcinoma suppressor gene. Cancer research54, 2765-2770.
Huang, Q., Shan, S., Braun, R.D., Lanzen, J., Anyrhambatla, G., Kong, G., Borelli, M., Corry, P., Dewhirst, M.W., and Li, C.Y. (1999). Noninvasive visualization of tumors in rodent dorsal skin window chambers. Nature biotechnology17, 1033-1035.
Humphreys, R.C., and Hennighausen, L. (2000). Transforming growth factor alpha and mouse models of human breast cancer. Oncogene19, 1085-1091.
Hunter, D.J., Kraft, P., Jacobs, K.B., Cox, D.G., Yeager, M., Hankinson, S.E., Wacholder, S., Wang, Z., Welch, R., Hutchinson, A., et al. (2007). A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nature genetics39, 870-874.
International Agency for Reseacrh on Cancer. Globocan 2000: cancer incidence, mortality and prevalence worldwide. Lyon, France: IARC Press.2001.
Iorio, M.V., Ferracin, M., Liu, C.G., Veronese, A., Spizzo, R., Sabbioni, S., Magri, E., Pedriali, M., Fabbri, M., Campiglio, M., et al. (2005). MicroRNA gene expression deregulation in human breast cancer. Cancer research65, 7065-7070.
Isaacs, J.T. (1986). Genetic control of resistance to chemically induced mammary adenocarcinogenesis in the rat. Cancer research46, 3958-3963.
Isaacs, J.T. (1988). Inheritance of a genetic factor from the Copenhagen rat and the suppression of chemically induced mammary adenocarcinogenesis. Cancer research 48, 2204-2213.
Jain, M., Arvanitis, C., Chu, K., Dewey, W., Leonhardt, E., Trinh, M., Sundberg, C.D., Bishop, J.M., and Felsher, D.W. (2002). Sustained loss of a neoplastic phenotype by brief inactivation of MYC. Science (New York, NY297, 102-104.
Janke, J., Schluter, K., Jandrig, B., Theile, M., Kolble, K., Arnold, W., Grinstein, E., Schwartz, A., Estevez-Schwarz, L., Schlag, P.M., et al.(2000). Suppression of tumorigenicity in breast cancer cells by the microfilament protein profilin 1. The Journal of experimental medicine191, 1675-1686.
Jemal, A., Siegel, R., Ward, E., Murray, T., Xu, J., and Thun, M.J. (2007). Cancer statistics, 2007. CA: a cancer journal for clinicians57, 43-66.
Jerry, D.J., Kittrell, F.S., Kuperwasser, C., Laucirica, R., Dickinson, E.S., Bonilla, P.J., Butel, J.S., and Medina, D. (2000). A mammary-specific model demonstrates the role of the p53 tumor suppressor gene in tumor development. Oncogene19, 1052-1058.
Jiang, J., Neubauer, B.L., Graff, J.R., Chedid, M., Thomas, J.E., Roehm, N.W., Zhang, S., Eckert, G.J., Koch, M.O., Eble, J.N., et al.(2002). Expression of group IIA secretory phospholipase A2 is elevated in prostatic intraepithelial neoplasia and adenocarcinoma. The American journal of pathology160, 667-671.
Jiricny, J. (2006). The multifaceted mismatch-repair system. Nature reviews7, 335-346.
Johnson, J.E., Varkonyi, R.J., Schwalm, J., Cragle, R., Klein-Szanto, A., Patchefsky, A., Cukierman, E., von Mehren, M., and Broccoli, D. (2005a). Multiple mechanisms of telomere maintenance exist in liposarcomas. Clin Cancer Res11, 5347-5355.
Johnson, S.M., Grosshans, H., Shingara, J., Byrom, M., Jarvis, R., Cheng, A., Labourier, E., Reinert, K.L., Brown, D., and Slack, F.J. (2005b). RAS is regulated by the let-7 microRNA family. Cell120, 635-647.
Kashiwagi, M., Friess, H., Uhl, W., Berberat, P., Abou-Shady, M., Martignoni, M., Anghelacopoulos, S.E., Zimmermann, A., and Buchler, M.W. (1999). Group II and IV phospholipase A(2) are produced in human pancreatic cancer cells and influence prognosis. Gut45, 605-612.
Kerbel, R.S. (2008). Tumor angiogenesis. The New England journal of medicine 358, 2039- 2049.
Kerr, J.F., Wyllie, A.H., and Currie, A.R. (1972). Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. British journal of cancer 26, 239- 257.
Key, T., Appleby, P., Barnes, I., and Reeves, G. (2002). Endogenous sex hormones and breast cancer in postmenopausal women: reanalysis of nine prospective studies. Journal of the National Cancer Institute94, 606-616.
Kim, N.W., Piatyszek, M.A., Prowse, K.R., Harley, C.B., West, M.D., Ho, P.L., Coviello, G.M., Wright, W.E., Weinrich, S.L., and Shay, J.W. (1994). Specific association of human telomerase activity with immortal cells and cancer. Science (New York, NY 266, 2011-2015.
Kim, U., Clifton, K.H., and Furth, J. (1960). A highly inbred line of Wistar rats yielding spontaneous mammo-somatotropic pituitary and other tumors. Journal of the National Cancer Institute24, 1031-1055.
Kindler-Rohrborn, A., Kind, A.B., Koelsch, B.U., Fischer, C., and Rajewsky, M.F. (2000).
Suppression of ethylnitrosourea-induced schwannoma development involves elimination of neu/erbB-2 mutant premalignant cells in the resistant BDIV rat strain.
Cancer research60, 4756-4760.
Knudson, A.G., Jr. (1971). Mutation and cancer: statistical study of retinoblastoma.
Proceedings of the National Academy of Sciences of the United States of America68, 820-823.
Korkola, J.E., and Archer, M.C. (1999). Resistance to mammary tumorigenesis in Copenhagen rats is associated with the loss of preneoplastic lesions. Carcinogenesis 20, 221-227.
Korkola, J.E., Wood, G.A., and Archer, M.C. (1997). Resistance to chemically-induced mammary tumors in Copenhagen X nude-derived F2 athymic rats: evidence that T-cell immunity is not involved in Copenhagen resistance. Carcinogenesis18, 53-57.
Kozak, C., Peters, G., Pauley, R., Morris, V., Michalides, R., Dudley, J., Green, M., Davisson, M., Prakash, O., Vaidya, A., et al. (1987). A standardized nomenclature for endogenous mouse mammary tumor viruses. Journal of virology61, 1651-1654.
Lai, E.C. (2002). Micro RNAs are complementary to 3' UTR sequence motifs that mediate negative post-transcriptional regulation. Nature genetics30, 363-364.
Lan, H., Kendziorski, C.M., Haag, J.D., Shepel, L.A., Newton, M.A., and Gould, M.N.
(2001). Genetic loci controlling breast cancer susceptibility in the Wistar-Kyoto rat.
Genetics157, 331-339.
Lancaster, M., Rouse, J., and Hunter, K.W. (2005). Modifiers of mammary tumor progression and metastasis on mouse chromosomes 7, 9, and 17. Mamm Genome16, 120-126.
Lavin, M.F., and Shiloh, Y. (1997). The genetic defect in ataxia-telangiectasia. Annual review of immunology15, 177-202.
Lazzerini Denchi, E., Attwooll, C., Pasini, D., and Helin, K. (2005). Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland.
Molecular and cellular biology25, 2660-2672.
Le Voyer, T., Lu, Z., Babb, J., Lifsted, T., Williams, M., and Hunter, K. (2000). An epistatic interaction controls the latency of a transgene-induced mammary tumor. Mamm Genome11, 883-889.
Lella, V., Stieber, D., Riviere, M., Szpirer, J., and Szpirer, C. (2007). Mammary cancer resistance and precocious mammary differentiation in the WKY rat: identification of 2 quantitative trait loci. International journal of cancer121, 1738-1743.
Lewis, B.P., Burge, C.B., and Bartel, D.P. (2005). Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120, 15-20.
Londono-Vallejo, J.A., Der-Sarkissian, H., Cazes, L., Bacchetti, S., and Reddel, R.R. (2004).
Alternative lengthening of telomeres is characterized by high rates of telomeric exchange. Cancer research64, 2324-2327.
Lozano, G., and Elledge, S.J. (2000). p53 sends nucleotides to repair DNA. Nature 404, 24- 25.
Lu, J., Wei, Q., Bondy, M.L., Li, D., Brewster, A., Shete, S., Yu, T.K., Sahin, A., Meric- Bernstam, F., Hunt, K.K., et al. (2006). Polymorphisms and haplotypes of the NBS1 gene are associated with risk of sporadic breast cancer in non-Hispanic white women
<or=55 years. Carcinogenesis27, 2209-2216.
Macleod, K. (2000). Tumor suppressor genes. Current opinion in genetics & development10, 81-93.
MacPhee, M., Chepenik, K.P., Liddell, R.A., Nelson, K.K., Siracusa, L.D., and Buchberg, A.M. (1995). The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia. Cell81, 957-966.
Maekawa, T., Shinagawa, T., Sano, Y., Sakuma, T., Nomura, S., Nagasaki, K., Miki, Y., Saito- Ohara, F., Inazawa, J., Kohno, T., et al. (2007). Reduced levels of ATF-2 predispose mice to mammary tumors. Molecular and cellular biology27, 1730-1744.
Magdolen, V., Oechsner, U., Muller, G., and Bandlow, W. (1988). The intron-containing gene for yeast profilin (PFY) encodes a vital function. Molecular and cellular biology 8, 5108-5115.
Malumbres, M., and Barbacid, M. (2003). RAS oncogenes: the first 30 years. Nat Rev Cancer 3, 459-465.
Martin, A.M., and Weber, B.L. (2000). Genetic and hormonal risk factors in breast cancer.
Journal of the National Cancer Institute92, 1126-1135.
Mayaudon, J., Yan, S.H., and Wallon, J. (1998). A proposed estimate of the tumor aggressiveness of human breast cancer using radiorespirometry. Biochemistry and molecular biology international45, 1073-1079.
Meier, P., Finch, A., and Evan, G. (2000). Apoptosis in development. Nature407, 796-801.
Meijers-Heijboer, H., van den Ouweland, A., Klijn, J., Wasielewski, M., de Snoo, A., Oldenburg, R., Hollestelle, A., Houben, M., Crepin, E., van Veghel-Plandsoen, M., et al.(2002). Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations. Nature genetics31, 55-59.
Miki, Y., Swensen, J., Shattuck-Eidens, D., Futreal, P.A., Harshman, K., Tavtigian, S., Liu, Q., Cochran, C., Bennett, L.M., Ding, W., et al.(1994). A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science (New York, NY266, 66-71.
Mironchik, Y., Winnard, P.T., Jr., Vesuna, F., Kato, Y., Wildes, F., Pathak, A.P., Kominsky, S., Artemov, D., Bhujwalla, Z., Van Diest, P., et al. (2005). Twist overexpression induces in vivo angiogenesis and correlates with chromosomal instability in breast cancer.
Cancer research65, 10801-10809.
Miyashita, T., Krajewski, S., Krajewska, M., Wang, H.G., Lin, H.K., Liebermann, D.A., Hoffman, B., and Reed, J.C. (1994). Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Oncogene9, 1799-1805.
Moyer, P. (2007). 29th Annual Meeting of the San Antonio Breast Cancer Symposium, TX, USA; Dec 14-18, 2006. The lancet oncology8, 106.
Muntoni, A., and Reddel, R.R. (2005). The first molecular details of ALT in human tumor cells. Human molecular genetics14 Spec No. 2, R191-196.
Nakano, K., and Vousden, K.H. (2001). PUMA, a novel proapoptotic gene, is induced by p53. Molecular cell7, 683-694.
National Cancer Institute. devCan: Probably of developing or dying of cancer software.
V6.1.0.2006. Statistical research and Applications branch.
Nevanlinna, H., and Bartek, J. (2006). The CHEK2 gene and inherited breast cancer susceptibility. Oncogene25, 5912-5919.
O'Donnell, K.A., Wentzel, E.A., Zeller, K.I., Dang, C.V., and Mendell, J.T. (2005). c-Myc- regulated microRNAs modulate E2F1 expression. Nature435, 839-843.
Oda, E., Ohki, R., Murasawa, H., Nemoto, J., Shibue, T., Yamashita, T., Tokino, T., Taniguchi, T., and Tanaka, N. (2000). Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science (New York, NY 288, 1053- 1058.
Okada, F., Rak, J.W., Croix, B.S., Lieubeau, B., Kaya, M., Roncari, L., Shirasawa, S., Sasazuki, T., and Kerbel, R.S. (1998). Impact of oncogenes in tumor angiogenesis:
mutant K-ras up-regulation of vascular endothelial growth factor/vascular permeability factor is necessary, but not sufficient for tumorigenicity of human colorectal carcinoma cells. Proceedings of the National Academy of Sciences of the United States of America95, 3609-3614.
Oltvai, Z.N., and Korsmeyer, S.J. (1994). Checkpoints of dueling dimers foil death wishes.
Cell79, 189-192.
Oltvai, Z.N., Milliman, C.L., and Korsmeyer, S.J. (1993). Bcl-2 heterodimerizes in vivo with
a conserved homolog, Bax, that accelerates programmed cell death. Cell74, 609-619.
Pasquinelli, A.E., Reinhart, B.J., Slack, F., Martindale, M.Q., Kuroda, M.I., Maller, B., Hayward, D.C., Ball, E.E., Degnan, B., Muller, P., et al. (2000). Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature408, 86-89.
Pelengaris, S., Khan, M., and Evan, G.I. (2002). Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression. Cell109, 321-334.
Perry, J.J., Fan, L., and Tainer, J.A. (2007). Developing master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair. Neuroscience145, 1280-1299.
Pharoah, P.D., Antoniou, A., Bobrow, M., Zimmern, R.L., Easton, D.F., and Ponder, B.A.
(2002). Polygenic susceptibility to breast cancer and implications for prevention.
Nature genetics31, 33-36.
Pike, M.C., and Spicer, D.V. (1993). The chemoprevention of breast cancer by reducing sex steroid exposure: perspectives from epidemiology. Journal of cellular biochemistry 17G, 26-36.
Quan, X., Laes, J.F., Stieber, D., Riviere, M., Russo, J., Wedekind, D., Coppieters, W., Farnir, F., Georges, M., Szpirer, J., et al. (2006). Genetic identification of distinct loci controlling mammary tumor multiplicity, latency, and aggressiveness in the rat. Mamm Genome17, 310-321.
Rahman, N., Seal, S., Thompson, D., Kelly, P., Renwick, A., Elliott, A., Reid, S., Spanova, K., Barfoot, R., Chagtai, T., et al. (2007). PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene. Nature genetics39, 165-167.
Rak, J., Mitsuhashi, Y., Sheehan, C., Tamir, A., Viloria-Petit, A., Filmus, J., Mansour, S.J., Ahn, N.G., and Kerbel, R.S. (2000). Oncogenes and tumor angiogenesis: differential modes of vascular endothelial growth factor up-regulation in ras-transformed epithelial cells and fibroblasts. Cancer research60, 490-498.
Rapp, J.P. (2000). Genetic analysis of inherited hypertension in the rat. Physiological reviews 80, 135-172.
Ravi, R., Mookerjee, B., Bhujwalla, Z.M., Sutter, C.H., Artemov, D., Zeng, Q., Dillehay, L.E., Madan, A., Semenza, G.L., and Bedi, A. (2000). Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha. Genes & development 14, 34-44.
Reinhart, B.J., Slack, F.J., Basson, M., Pasquinelli, A.E., Bettinger, J.C., Rougvie, A.E., Horvitz, H.R., and Ruvkun, G. (2000). The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature403, 901-906.
Robins, H., and Press, W.H. (2005). Human microRNAs target a functionally distinct population of genes with AT-rich 3' UTRs. Proceedings of the National Academy of Sciences of the United States of America102, 15557-15562.
Rolstad, B. (2001). The athymic nude rat: an animal experimental model to reveal novel aspects of innate immune responses? Immunological reviews184, 136-144.
Romieu, I., Berlin, J.A., and Colditz, G. (1990). Oral contraceptives and breast cancer.
Review and meta-analysis. Cancer66, 2253-2263.
Roshani, L., Wedekind, D., Szpirer, J., Taib, Z., Szpirer, C., Beckmann, B., Riviere, M., Hedrich, H.J., and Klinga-Levan, K. (2001). Genetic identification of multiple susceptibility genes involved in the development of endometrial carcinoma in a rat model. International journal of cancer94, 795-799.
Russo, I.H., and Russo, J. (1996). Mammary gland neoplasia in long-term rodent studies.
Environmental health perspectives104, 938-967.
Russo, J., Wilgus, G., Tait, L., and Russo, I.H. (1981). Influence of age and parity on the
susceptibility of rat mammary gland epithelial cells in primary cultures to 7,12- dimethylbenz(a)anthracene. In vitro17, 877-884.
Russo, M.T., Blasi, M.F., Chiera, F., Fortini, P., Degan, P., Macpherson, P., Furuichi, M., Nakabeppu, Y., Karran, P., Aquilina, G., et al. (2004). The oxidized deoxynucleoside triphosphate pool is a significant contributor to genetic instability in mismatch repair- deficient cells. Molecular and cellular biology24, 465-474.
Sahlin, P., Windh, P., Lauritzen, C., Emanuelsson, M., Gronberg, H., and Stenman, G. (2007).
Women with Saethre-Chotzen syndrome are at increased risk of breast cancer. Genes, chromosomes & cancer46, 656-660.
Samuelson, D.J., Aperavich, B.A., Haag, J.D., and Gould, M.N. (2005). Fine mapping reveals multiple loci and a possible epistatic interaction within the mammary carcinoma susceptibility quantitative trait locus, Mcs5. Cancer research65, 9637-9642.
Samuelson, D.J., Hesselson, S.E., Aperavich, B.A., Zan, Y., Haag, J.D., Trentham-Dietz, A., Hampton, J.M., Mau, B., Chen, K.S., Baynes, C., et al. (2007). Rat Mcs5a is a compound quantitative trait locus with orthologous human loci that associate with breast cancer risk. Proceedings of the National Academy of Sciences of the United States of America104, 6299-6304.
Sandelin, K., Apffelstaedt, J.P., Abdullah, H., Murray, E.M., and Ajuluchuku, E.U. (2002).
Breast Surgery International--breast cancer in developing countries. Scand J Surg 91, 222-226.
Schaffer, B.S., Lachel, C.M., Pennington, K.L., Murrin, C.R., Strecker, T.E., Tochacek, M., Gould, K.A., Meza, J.L., McComb, R.D., and Shull, J.D. (2006). Genetic bases of estrogen-induced tumorigenesis in the rat: mapping of loci controlling susceptibility to mammary cancer in a Brown Norway x ACI intercross. Cancer research 66, 7793- 7800.
Scicchitano, D.A., and Mellon, I. (1997). Transcription and DNA damage: a link to a kink.
Environmental health perspectives105 Suppl 1, 145-153.
Seal, S., Thompson, D., Renwick, A., Elliott, A., Kelly, P., Barfoot, R., Chagtai, T., Jayatilake, H., Ahmed, M., Spanova, K., et al. (2006). Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles. Nature genetics38, 1239-1241.
Sedlak, T.W., Oltvai, Z.N., Yang, E., Wang, K., Boise, L.H., Thompson, C.B., and Korsmeyer, S.J. (1995). Multiple Bcl-2 family members demonstrate selective dimerizations with Bax. Proceedings of the National Academy of Sciences of the United States of America92, 7834-7838.
Semenza, G.L. (1999). Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. Annual review of cell and developmental biology15, 551-578.
Serrano, M., Lin, A.W., McCurrach, M.E., Beach, D., and Lowe, S.W. (1997). Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell88, 593-602.
Shachaf, C.M., Kopelman, A.M., Arvanitis, C., Karlsson, A., Beer, S., Mandl, S., Bachmann, M.H., Borowsky, A.D., Ruebner, B., Cardiff, R.D., et al. (2004). MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer.
Nature431, 1112-1117.
Shay, J.W., Zou, Y., Hiyama, E., and Wright, W.E. (2001). Telomerase and cancer. Human molecular genetics10, 677-685.
Shellabarger, C.J., Stone, J.P., and Holtzman, S. (1978). Rat differences in mammary tumor induction with estrogen and neutron radiation. Journal of the National Cancer Institute 61, 1505-1508.
Shepel, L.A., Lan, H., Haag, J.D., Brasic, G.M., Gheen, M.E., Simon, J.S., Hoff, P., Newton, M.A., and Gould, M.N. (1998). Genetic identification of multiple loci that control
breast cancer susceptibility in the rat. Genetics149, 289-299.
Shiloh, Y. (2006). The ATM-mediated DNA-damage response: taking shape. Trends in biochemical sciences31, 402-410.
Shima, N., Alcaraz, A., Liachko, I., Buske, T.R., Andrews, C.A., Munroe, R.J., Hartford, S.A., Tye, B.K., and Schimenti, J.C. (2007). A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice. Nature genetics39, 93-98.
Shull. J.D., Hormonal Carcinogenesis, in: Encyclopedia of cancer, (Vol.2), J.R.Bertino, ed.,Academic Press, San Diego, CA, 2002, pp.417-428.
Shull, J.D. (2007). The rat oncogenome: comparative genetics and genomics of rat models of mammary carcinogenesis. Breast disease28, 69-86.
Spady, T.J., Harvell, D.M., Snyder, M.C., Pennington, K.L., McComb, R.D., and Shull, J.D.
(1998). Estrogen-induced tumorigenesis in the Copenhagen rat: disparate susceptibilities to development of prolactin-producing pituitary tumors and mammary carcinomas. Cancer letters124, 95-103.
Stark, A., Brennecke, J., Bushati, N., Russell, R.B., and Cohen, S.M. (2005). Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution. Cell123, 1133-1146.
Steffen, J., Nowakowska, D., Niwinska, A., Czapczak, D., Kluska, A., Piatkowska, M., Wisniewska, A., and Paszko, Z. (2006). Germline mutations 657del5 of the NBS1 gene contribute significantly to the incidence of breast cancer in Central Poland.
International journal of cancer119, 472-475.
Stieber, D., Piessevaux, G., Riviere, M., Laes, J.F., Quan, X., Szpirer, J., and Szpirer, C.
(2007). Isolation of two regions on rat chromosomes 5 and 18 affecting mammary cancer susceptibility. International journal of cancer120, 1678-1683.
Stieber, D. (2005). Analyse génétique de la sensibilité au cancer mammaire. Thèse de doctorat en Sciences. ULB.
Stone, J.P., Holtzman, S., and Shellabarger, C.J. (1979). Neoplastic responses and correlated plasma prolactin levels in diethylstilbestrol-treated ACI and Sprague-Dawley rats.
Cancer research39, 773-778.
Subba Rao, K. (2007). Mechanisms of disease: DNA repair defects and neurological disease.
Nature clinical practice3, 162-172.
Sun, M., Hurst, L.D., Carmichael, G.G., and Chen, J. (2005). Evidence for a preferential targeting of 3'-UTRs by cis-encoded natural antisense transcripts. Nucleic acids research33, 5533-5543.
Sun, T., Gao, Y., Tan, W., Ma, S., Shi, Y., Yao, J., Guo, Y., Yang, M., Zhang, X., Zhang, Q., et al.(2007). A six-nucleotide insertion-deletion polymorphism in the CASP8 promoter is associated with susceptibility to multiple cancers. Nature genetics39, 605-613.
Swift, M., Morrell, D., Massey, R.B., and Chase, C.L. (1991). Incidence of cancer in 161 families affected by ataxia-telangiectasia. The New England journal of medicine 325, 1831-1836.
Szpirer, C., and Szpirer, J. (2007). Mammary cancer susceptibility: human genes and rodent models. Mamm Genome18, 817-831.
Tavtigian, S.V., Simard, J., Rommens, J., Couch, F., Shattuck-Eidens, D., Neuhausen, S., Merajver, S., Thorlacius, S., Offit, K., Stoppa-Lyonnet, D., et al.(1996). The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds. Nature genetics 12, 333-337.
Theodorou, V., Kimm, M.A., Boer, M., Wessels, L., Theelen, W., Jonkers, J., and Hilkens, J.
(2007). MMTV insertional mutagenesis identifies genes, gene families and pathways involved in mammary cancer. Nature genetics39, 759-769.
Thompson, C.B. (1995). Apoptosis in the pathogenesis and treatment of disease. Science (New York, NY267, 1456-1462.
Tong, W.M., Yang, Y.G., Cao, W.H., Galendo, D., Frappart, L., Shen, Y., and Wang, Z.Q.
(2007). Poly(ADP-ribose) polymerase-1 plays a role in suppressing mammary tumourigenesis in mice. Oncogene26, 3857-3867.
Touqui, L., & Alaoui-El-Azher, M. (2001). Mammalian secreted phospholipases A2 and their pathophysiological significance in inflammatory diseases. Curr Mol Med.1,739-54.
Review.
Uganda Breast Cancer Working group. Breast cancer guidelines for Uganda.Afr Health.3003;
3:47-50.
Vacek, P.M., and Geller, B.M. (2004). A prospective study of breast cancer risk using routine mammographic breast density measurements. Cancer Epidemiol Biomarkers Prev13, 715-722.
Vahteristo, P., Bartkova, J., Eerola, H., Syrjakoski, K., Ojala, S., Kilpivaara, O., Tamminen, A., Kononen, J., Aittomaki, K., Heikkila, P., et al. (2002). A CHEK2 genetic variant contributing to a substantial fraction of familial breast cancer. American journal of human genetics71, 432-438.
Van de Vijver, M.J., and Nusse, R. (1991). The molecular biology of breast cancer.
Biochimica et biophysica acta1072, 33-50.
Ventura, A., Kirsch, D.G., McLaughlin, M.E., Tuveson, D.A., Grimm, J., Lintault, L., Newman, J., Reczek, E.E., Weissleder, R., and Jacks, T. (2007). Restoration of p53 function leads to tumour regression in vivo. Nature445, 661-665.
Vogel, H.H., Jr., and Turner, J.E. (1982). Genetic component in rat mammary carcinogenesis.
Radiation research89, 264-273.
Wang, R.A., Zhang, H., Balasenthil, S., Medina, D., and Kumar, R. (2006). PAK1 hyperactivation is sufficient for mammary gland tumor formation. Oncogene25, 2931- 2936.
Wang, T.C., Cardiff, R.D., Zukerberg, L., Lees, E., Arnold, A., and Schmidt, E.V. (1994).
Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice. Nature 369, 669-671.
Ward, J.M., and Devor-Henneman, D.E. (2004). Mouse models of human familial cancer syndromes. Toxicologic pathology32 Suppl 1, 90-98.
Welcsh, P.L., Owens, K.N., and King, M.C. (2000). Insights into the functions of BRCA1 and BRCA2. Trends Genet16, 69-74.
White, E. (1987). Projected changes in breast cancer incidence due to the trend toward delayed childbearing. American journal of public health77, 495-497.
Wood, G.A., Korkola, J.E., and Archer, M.C. (2001). Resistance of Copenhagen rats to hepatocarcinogenesis does not involve T-cell immunity. Carcinogenesis22, 357-359.
Wood, R.D., Mitchell, M., and Lindahl, T. (2005). Human DNA repair genes, 2005. Mutation research577, 275-283.
Wooster, R., Bignell, G., Lancaster, J., Swift, S., Seal, S., Mangion, J., Collins, N., Gregory, S., Gumbs, C., and Micklem, G. (1995). Identification of the breast cancer susceptibility gene BRCA2. Nature378, 789-792.
Wood, R.D. (1996) DNA repair in eukéryotes. Annu. Rev. Biochem., 65, 135-167.
Wyllie, A.H., Kerr, J.F., and Currie, A.R. (1980). Cell death: the significance of apoptosis.
International review of cytology68, 251-306.
Wyllie, A.H., Morris, R.G., Smith, A.L., and Dunlop, D. (1984). Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis. The Journal of pathology142, 67-77.
Wyman, C., and Kanaar, R. (2006). DNA double-strand break repair: all's well that ends well.
Annual review of genetics40, 363-383.
Xue, W., Zender, L., Miething, C., Dickins, R.A., Hernando, E., Krizhanovsky, V., Cordon- Cardo, C., and Lowe, S.W. (2007). Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature445, 656-660.
Young, L.C., Hays, J.B., Tron, V.A., and Andrew, S.E. (2003). DNA mismatch repair proteins:
potential guardians against genomic instability and tumorigenesis induced by ultraviolet photoproducts. The Journal of investigative dermatology121, 435-440.
Zhang, B., Pan, X., Cannon, C.H., Cobb, G.P., and Anderson, T.A. (2006a). Conservation and divergence of plant microRNA genes. Plant J46, 243-259.
Zhang, L., Huang, J., Yang, N., Greshock, J., Megraw, M.S., Giannakakis, A., Liang, S., Naylor, T.L., Barchetti, A., Ward, M.R., et al. (2006b). microRNAs exhibit high frequency genomic alterations in human cancer. Proceedings of the National Academy of Sciences of the United States of America103, 9136-9141.
Zhu, J., Woods, D., McMahon, M., and Bishop, J.M. (1998). Senescence of human fibroblasts induced by oncogenic Raf. Genes & development12, 2997-3007.
Zuo, T., Wang, L., Morrison, C., Chang, X., Zhang, H., Li, W., Liu, Y., Wang, Y., Liu, X., Chan, M.W., et al.(2007). FOXP3 is an X-linked breast cancer suppressor gene and an important repressor of the HER-2/ErbB2 oncogene. Cell129, 1275-1286.
Sites Internet et bases de données
Affymetrix :https://www.affymetrix.com
American Cancer Society :http://caonline.amcancersoc.org
DNA Vision:http://www.dnavision.be
Ensembl Genome Browser, Ensemble:http://www.esemble.org
HapMap projest :http://www.hapmap.org
Institut de pathologie et génétique (IPG) :http://www.ipg.be
miRBase (Sanger) :http://microrna.sanger.ac.uk
Organisation mondiale de la Santé :http://www.who.int/en/index.html
Rat Genome Database (RGD):http://www.rgd.mcw.edu
NCBI Entrez genome, Mapiviewer: http://www. ncbi.nlm.nih.org/mapview
Rat Genome and Nomenclature Commitee:
http://www.informatics.jax.org/mgihome/nomen/gene.shtml#nsqtl).
U.S. National Cancer Institute: http://www.srab.cancer.gov
