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Incidence of sleep apnea and association with atrial fibrillation in an unselected pacemaker population: Results of the observational

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Incidence of sleep apnea and association with atrial fibrillation in an unselected pacemaker population: Results of the observational

RESPIRE study

MARTI-ALMOR, Julio, et al .

Abstract

Patients with atrial fibrillation (AF) often have sleep apnea (SA), but diagnosis of SA with polysomnography is costly. SA monitoring is a pacemaker feature that measures respiratory disturbance index, the sum of abnormal respiratory events divided by sleep duration.

MARTI-ALMOR, Julio, et al . Incidence of sleep apnea and association with atrial fibrillation in an unselected pacemaker population: Results of the observational RESPIRE study. Heart

Rhythm , 2020, vol. 17, no. 2, p. 195-202

PMID : 31493591

DOI : 10.1016/j.hrthm.2019.09.001

Available at:

http://archive-ouverte.unige.ch/unige:149113

Disclaimer: layout of this document may differ from the published version.

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80%

0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18

AF in patients with severe SA (%)

Time (months)

FMS <6 minutes in 24 hours

6 minutes< FMS <6 hours in 24 hours 6 hours< FMS <24 hours in 24 hours 24 hours< FMS <7 days in 7 days FMS for 7 consecutive days

Severe SA

Non-severe SA

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18

AF in patients with non-severe SA (%)

Time (months)

FMS <6 minutes in 24 hours

6 minutes< FMS <6 hours in 24 hours 6 hours< FMS <24 hours in 24 hours 24 hours< FMS <7 days in 7 days FMS for 7 consecutive days

Supplementary Figure 1. Graphical depiction of the association between different burdens of atrial fibrillation (AF), based on duration of fallback mode

switch (FMS), and sleep apnea (SA) in the modified intention-to-treat (mITT) population (n=1024)

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