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Identification of the molecular origins of disease in a cohort of patients with suspected congenital disorders of glycosylation (CDG)

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Academic year: 2021

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Figure

Figure 2: M6P-labelled lysosomal hydrolase targeting from the Golgi apparatus to the lysosome
Figure 4: The “key-lock” theory of glycan-GBP interaction.   The dashed lines represent different binding mechanisms
Figure 5:  Bimolecular nucleophilic substitution (SN 2 ) reaction of a monosaccharide addition to an
Figure 6: The biosynthetic and interconversion pathways of UDP-Glc and UDP-Gal in the cytoplasm
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