HAL Id: hal-01601316
https://hal.archives-ouvertes.fr/hal-01601316
Submitted on 3 Jun 2020
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Different conditioning protocols result in distinct lymphopenic environments: consequences for regulatory
T cells and anti-tumor immunotherapy
Mathieu Epardaud, Valérie Dardalhon, Dorotha Klysz, Valérie Zimmermann, Naomi Taylor
To cite this version:
Mathieu Epardaud, Valérie Dardalhon, Dorotha Klysz, Valérie Zimmermann, Naomi Taylor. Different conditioning protocols result in distinct lymphopenic environments: consequences for regulatory T cells and anti-tumor immunotherapy. Annual Meeting of the French Society for Immunology, Nov 2011, Montpellier, France. 2011, Annual Meeting of the French Society for Immunology. �hal-01601316�
CONGRES ANNUEL DE LA
SOCIÉTÉ FRANCAISE D’IMMUNOLOGIE 8 - 10 NOVEMBRE 2011
LE CORUM, MONTPELLIER
PROGRAMME
Tuesday November 8th, 2011
08.00 ZĞŐŝƐƚƌĂƟŽŶ
08.30 /ŶƚƌŽĚƵĐƟŽŶͬtĞůĐŽŵĞ
PLENARY SESSION INNATE IMMUNITY
Marc Dalod, Tdb -‐ Chairs 08.45 ,ŽƐƚͲŵŝĐƌŽďŝŽƚĂŝŵŵƵŶĞŚŽŵĞŽƐƚĂƐŝƐĂƐĂĐƌŝƟĐĂůĚĞƚĞƌŵŝŶĂŶƚŽĨƚŚĞŝŶƚĞƐƟŶĂůďĂƌƌŝĞƌ
Emma Slack -‐ Universität Bern, Switzerland
09.15 DƵĐŽƐĂůƐƐŽĐŝĂƚĞĚ/ŶǀĂƌŝĂŶƚd;D/dͿůLJŵƉŚŽĐLJƚĞƐ͗ĂŶĞǀŽůƵƟŽŶĂƌŝůLJĐŽŶƐĞƌǀĞĚƐƵďƐĞƚǁŝƚŚĂŶƟͲďĂĐƚĞƌŝĂůĂĐƟǀŝƚLJ KůŝǀĞƌ>ĂŶƚnjͲ/ŶƐƟƚƵƚƵƌŝĞ͕WĂƌŝƐ͕&ƌĂŶĐĞ
09.45 ^ƚƌĞƐƐƉĂƚŚǁĂLJƐƉƌŽŵŽƚŝŶŐŝŶĨůĂŵŵĂƚŝŽŶ
&ĂďŝŽDĂƌƟŶŽŶͲ>ĂƵƐĂŶŶĞhŶŝǀĞƌƐŝƚLJ͕ƉĂůŝŶŐƵĞƐ͕^ǁŝƚnjĞƌůĂŶĚ 10.15 ŽīĞĞƌĞĂŬͬdžŚŝďŝƟŽŶ
10.45 WŽƐƚĞƌƐƐĞƐƐŝŽŶƐ
THEMATICS SESSIONS IMMUNOLOGIC RECONSTITUTION
WŝĞƌƌĞŽƌďĞĂƵ͕/ƐĂďĞůůĞŶĚƌĠͲ^ĐŚŵƵƚnjͲŚĂŝƌƐ 11.15 dŝƚůĞƚŽďĞĐŽŶĮƌŵĞĚ
WŝĞƌƌĞŽƌďĞĂƵ͕,ƀƉŝƚĂů^ĂŝŶƚůŽŝ͕DŽŶƚƉĞůůŝĞƌ͕&ƌĂŶĐĞ
ZĞĐŽŶƐƟƚƵƟŽŶŝŵŵƵŶŝƚĂŝƌĞĂƉƌğƐŐƌĞīĞĚĞĐĞůůƵůĞƐƐŽƵĐŚĞƐŚĠŵĂƚŽƉŽŢĠƟƋƵĞƐ /ƐĂďĞůůĞŶĚƌĠͲ^ĐŚŵƵƚnjͲ/ŶƐĞƌŵhϳϲϴ͕,ƀƉŝƚĂůEĞĐŬĞƌ͕WĂƌŝƐ͕&ƌĂŶĐĞ
^ĞůĞĐƚĞĚƉƌĞƐĞŶƚĂƟŽŶƐĨƌŽŵƐƵďŵŝƩĞĚĂďƐƚƌĂĐƚƐ
IMMUNE ACTIVATION AND TUMORIGENESIS
:ĠƌŽŵĞ'ĂůŽŶ͕&ƌĂŶĕŽŝƐ'ŚŝƌŝŶŐŚĞůůŝͲŚĂŝƌƐ 11.15 dŝƚůĞƚŽďĞĐŽŶĮƌŵĞĚ
:ĠƌƀŵĞ'ĂůŽŶͲ/ŶƐĞƌŵhϴϳϮ͕ĞŶƚƌĞŝŽŵĠĚŝĐĂůĚĞƐŽƌĚĞůŝĞƌƐ͕WĂƌŝƐ͕&ƌĂŶĐĞ dŚĞƌŽůĞŽĨŝŵŵƵŶĞŝŶĮůƚƌĂƚĞŝŶŚƵŵĂŶďƌĞĂƐƚĐĂŶĐĞƌ
&ƌĂŶĕŽŝƐ'ŚŝƌŝŶŐŚĞůůŝͲ/ŶƐĞƌŵ͕Z/ϴϲϲ͕ŝũŽŶ͕&ƌĂŶĐĞ
^ĞůĞĐƚĞĚƉƌĞƐĞŶƚĂƟŽŶƐĨƌŽŵƐƵďŵŝƩĞĚĂďƐƚƌĂĐƚƐ
NEUROIMMUNOLOGY
ƵƌŬŚĂƌĚĞĐŚĞƌ͕^LJůǀĂŝŶ&ŝƐƐŽŶͲŚĂŝƌƐ 11.15 /ŶƚƌŽĚƵĐƟŽŶ
^LJůǀĂŝŶ&ŝƐƐŽŶͲ/ŶƐĞƌŵhϴϳϮ͕ĞŶƚƌĞŝŽŵĠĚŝĐĂůĚĞƐŽƌĚĞůŝĞƌƐ͕WĂƌŝƐ͕&ƌĂŶĐĞ dĐĞůůƉŽůĂƌŝnjĂƟŽŶĂŶĚĞīĞĐƚŽƌĐLJƚŽŬŝŶĞƐŝŶĂƵƚŽŝŵŵƵŶŝƚLJ
ƵƌŬŚĂƌĚĞĐŚĞƌͲhŶŝǀĞƌƐŝƚLJ,ŽƐƉŝƚĂůŽĨƵƌŝĐŚ͕^ǁŝƚnjĞƌůĂŶĚ
^ĞůĞĐƚĞĚƉƌĞƐĞŶƚĂƟŽŶƐĨƌŽŵƐƵďŵŝƩĞĚĂďƐƚƌĂĐƚƐ
12.45 >ƵŶĐŚͬsŝƐŝƚŽĨĞdžŚŝďŝƟŽŶĂƌĞĂ
PLENARY SESSION
LYMPHOCYTE DEVELOPMENT
^ŽƉŚŝĞnjŝŶĞ͕dďĚͲŚĂŝƌƐ 14.00 dŝƚůĞƚŽďĞĐŽŶĮƌŵĞĚ
&ƌĞĚĞƌŝĐĂ^ĂůůƵƐƚŽͲ/ŶƐƟƚƵƚĞĨŽƌZĞƐĞĂƌĐŚŝŶŝŽŵĞĚŝĐŝŶĞ͕ĞůůŝŶnjŽŶĂ͕^ǁŝƚnjĞƌůĂŶĚ ĞůƚĂͲůŝŬĞϰͬEŽƚĐŚƌĞŐƵůĂƚĞƐŝŶŇĂŵŵĂƚŽƌLJdĐĞůůƐĞůĨĐŽŶƚƌŽů
ůĞdžĂŶĚĞƌ^ĐŚĞīŽůĚͲDŝůƚĞŶLJŝŝŽƚĞĐ'ŵď,͕ĞƌŐŝƐĐŚ'ůĂĚďĂĐŚ͕'ĞƌŵĂŶLJ WƌŽĚƵĐƟŽŶĂŶĚƌŽůĞŽĨ/>ͲϮϮŝŶd>ZͲƚƌŝŐŐĞƌĞĚŝŶŇĂŵŵĂƚŽƌLJƉƌŽĐĞƐƐĞƐ͘
:ĞĂŶͲŚƌŝƐƚŽƉŚĞZĞŶĂƵůĚͲhŶŝǀĞƌƐŝƚĠĚĞ>ŽƵǀĂŝŶ͕ĞůŐŝƵŵ 15.30 ŽīĞĞƌĞĂŬͬdžŚŝďŝƟŽŶ
16.00 WŽƐƚĞƌƐƐĞƐƐŝŽŶƐ
THEMATICS SESSIONS TOLERANCE AND AUTOIMMUNITY
ĞŶŽŠƚ^ĂůŽŵŽŶ͕:ƵůŝĞŶŝĂŶĂͲŚĂŝƌƐ 16.30 /ŶŇĂŵŵĂƟŽŶŝƐĂĚƌŝǀŝŶŐĨŽƌĐĞƚŽďŽŽƐƚƌĞŐƵůĂƚŽƌLJdĐĞůůƐ
ĞŶŽŠƚ^ĂůŽŵŽŶͲEZ^͕hŶŝǀĞƌƐŝƚĠWŝĞƌƌĞĞƚDĂƌŝĞƵƌŝĞ͕WĂƌŝƐ͕&ƌĂŶĐĞ sŝƌĂůŝŶĨĞĐƟŽŶƉƌĞǀĞŶƚƐƚLJƉĞϭĚŝĂďĞƚĞƐƚŚƌŽƵŐŚE<dͲƉĐƌŽƐƐƚĂůŬƐ :ƵůŝĞŶŝĂŶĂͲ/ŶƐĞƌŵhϵϴϲ͕,ƀƉŝƚĂů^ĂŝŶƚͲsŝŶĐĞŶƚĚĞWĂƵů͕WĂƌŝƐ͕&ƌĂŶĐĞ
^ĞůĞĐƚĞĚƉƌĞƐĞŶƚĂƟŽŶƐĨƌŽŵƐƵďŵŝƩĞĚĂďƐƚƌĂĐƚƐ
IMMUNE RESPONSES ASSOCIATED WITH GENE THERAPY
ŶŶĞ 'ĂůLJ͕ 'ŝůůĞƐ DĂƌŽĚŽŶ Ͳ ŚĂŝƌƐ 16.30 dŝƚůĞƚŽďĞĐŽŶĮƌŵĞĚ
ŶŶĞ'ĂůLJͲ/ŶƐĞƌŵ͕'ĞŶĞƚŚŽŶ͕&ƌĂŶĐĞ
^ĞůĞĐƚĞĚƉƌĞƐĞŶƚĂƟŽŶƐĨƌŽŵƐƵďŵŝƩĞĚĂďƐƚƌĂĐƚƐ
THERAPEUTIC ANTIBODIES
,ĞƌǀĠtĂƟĞƌ͕dďĚͲŚĂŝƌƐ
16.30 /D'dͲKEdK>K'zĨŽƌŝŵŵƵŶŽŐůŽďƵůŝŶŽƌĂŶƟďŽĚLJ͕dĐĞůůƌĞĐĞƉƚŽƌĂŶĚŵĂũŽƌŚŝƐƚŽĐŽŵƉĂƟďŝůŝƚLJ͗/'ͬŐĂŶĚdZͬƉD,ŝŶƚĞƌĂĐƟŽŶƐ DĂƌŝĞͲWĂƵůĞ>ĞĨƌĂŶĐͲ/D'd͕/ŶƐƟƚƵƚĚĞ'ĠŶĠƟƋƵĞ,ƵŵĂŝŶĞ͕DŽŶƚƉĞůůŝĞƌ͕&ƌĂŶĐĞ
/ƐƐƵĞƐĂŶĚĐŚĂůůĞŶŐĞƐŝŶƚŚĞƉƌĞĐůŝŶŝĐĂůĂŶĚĐůŝŶŝĐĂůĚĞǀĞůŽƉŵĞŶƚŽĨŵŽŶŽĐůŽŶĂůƐĂŶƟďŽĚŝĞƐ ,ĞƌǀĠtĂƟĞƌͲhŶŝǀĞƌƐŝƚĠĞƚ,Zh͕EZ^'ZϯϮϲϬ͕dŽƵƌƐ͕&ƌĂŶĐĞ
dŚĞƐƉĞĐŝĮĐŝƟĞƐĂŶĚĨƵŶĐƟŽŶƐŽĨŚƵŵĂŶŵŽŶŽĐůŽŶĂůĂŶƟďŽĚŝĞƐĂŐĂŝŶƐƚƌĞƐƉŝƌĂƚŽƌLJǀŝƌƵƐĞƐ ,ĞƌŐĞŶ^ƉŝƚƐͲĐĂĚĞŵŝĐDĞĚŝĐĂůĞŶƚĞƌ͕ŵƐƚĞƌĚĂŵ͕dŚĞEĞƚŚĞƌůĂŶĚƐ
'ůLJĐŽƐLJůĂƟŽŶŽĨĂŶƟďŽĚLJƚŚĞƌĂƉĞƵƟĐƐ͗ĂƌŝƟĐĂůYƵĂůŝƚLJƩƌŝďƵƚĞ;YͿ ZŽLJ:ĞīĞƌŝƐͲhŶŝǀĞƌƐŝƚLJŽĨŝƌŵŝŶŐŚĂŵ͕h<
18.00 'ĞŶĞƌĂůƐƐĞŵďůLJŽĨƚŚĞ^&/ͬsŝƐŝƚŽĨĞdžŚŝďŝƟŽŶĂƌĞĂ;WĂƐƚĞƵƌZŽŽŵͿ
18.40 ^&/ͲDŝůƚĞŶLJŝzŽƵŶŐ/ŶǀĞƐƟŐĂƚŽƌǁĂƌĚ;WĂƐƚĞƵƌZŽŽŵͿ
18.40 'ĞŶĞƌĂůƐƐĞŵďůLJŽĨƚŚĞ^^/DͬsŝƐŝƚŽĨĞdžŚŝďŝƟŽŶĂƌĞĂ;ZŽŶĚĞůĞƚZŽŽŵͿ
19.00 ŽĐŬƚĂŝů
tĞĚŶĞƐĚĂLJEŽǀĞŵďĞƌϵƚŚ͕ϮϬϭϭ PLENARY SESSION
^/ WZ/E/W>^ K& Ed/ͳ/E&d/Kh^ /DDhE/dz
WŝĞƌƌĞ 'ĂůĂŶĂƵĚ͕ dďĚ Ͳ ŚĂŝƌƐ 08.45 ĞĐŽŶǀŽůƵƟŶŐϴdĐĞůůĞĸĐĂĐLJĂŐĂŝŶƐƚ,/s͗ĨƌŽŵƉŚĞŶŽƚLJƉĞƚŽĐůŽŶŽƚLJƉĞ
sŝĐƚŽƌƉƉĂLJͲ/ŶƐĞƌŵ͕hŶŝǀĞƌƐŝƚĠWŝĞƌƌĞĞƚDĂƌŝĞƵƌŝĞ͕WĂƌŝƐ͕&ƌĂŶĐĞ 09.15 ,ŽƐƚͲƉĂƚŚŽŐĞŶŝŶƚĞƌĂĐƟŽŶƐŝŶƚƵďĞƌĐƵůŽƐŝƐ
KůŝǀŝĞƌEĞLJƌŽůůĞƐͲhŶŝǀĞƌƐŝƚĠWĂƵů^ĂďĂƟĞƌ͕dŽƵůŽƵƐĞ͕&ƌĂŶĐĞ 09.45 KŶƚŚĞŐĞŶĞƟĐĂƌĐŚŝƚĞĐƚƵƌĞŽĨŝŶĨĞĐƟŽƵƐĚŝƐĞĂƐĞƐ
ůĞdžĂŶĚƌĞůĐĂŢƐͲ/ŶƐĞƌŵ͕&ĂĐƵůƚĠĚĞDĠĚĞĐŝŶĞEĞĐŬĞƌ͕WĂƌŝƐ͕&ƌĂŶĐĞ 10.15 ŽīĞĞƌĞĂŬͬdžŚŝďŝƟŽŶ
10.45 WŽƐƚĞƌƐƐĞƐƐŝŽŶƐ
THEMATICS SESSIONS LYMPHOCYTE SUBSETS
EĂŽŵŝdĂLJůŽƌ͕:ƵůŝĞŶDĂƌŝĞͲŚĂŝƌƐ 11.15 dŝƚůĞƚŽďĞĐŽŶĮƌŵĞĚ
EĂŽŵŝdĂLJůŽƌͲEZ^͕/ŶƐƟƚƵƚĚĞ'ĠŶĠƟƋƵĞDŽůĠĐƵůĂŝƌĞĚĞDŽŶƚƉĞůůŝĞƌ͕&ƌĂŶĐĞ dŝƚůĞƚŽďĞĐŽŶĮƌŵĞĚ
:ƵůŝĞŶDĂƌŝĞͲ/ŶƐĞƌŵhϱϵϬͲĞŶƚƌĞ>ĠŽŶĠƌĂƌĚ͕>LJŽŶ͕&ƌĂŶĐĞ
^ĞůĞĐƚĞĚƉƌĞƐĞŶƚĂƟŽŶƐĨƌŽŵƐƵďŵŝƩĞĚĂďƐƚƌĂĐƚƐ
/EEd /DDhE/dz / ͬ hdKͳ/E&>DDd/KE
/ƐĂďĞůůĞdŽƵŝƚŽƵ͕^ĞƚŚDĂƐƚĞƌƐͲŚĂŝƌƐ 11.15 ĐƟǀĂƟŽŶĂŶĚŝŶŚŝďŝƟŽŶŽĨƚŚĞŝŶŇĂŵŵĂƐŽŵĞ
^ĞƚŚDĂƐƚĞƌƐͲdƌŝŶŝƚLJŽůůĞŐĞ͕ƵďůŝŶ͕/ƌĞůĂŶĚ
^ĞůĞĐƚĞĚƉƌĞƐĞŶƚĂƟŽŶƐĨƌŽŵƐƵďŵŝƩĞĚĂďƐƚƌĂĐƚƐ
/E^d /DDhE/dz ͳ >KKͳ&/E' Zd,ZKWK ^>/s ͳ ^^^/KE /Zͳ^&/
:ĞƐƵƐ'͘sĂůĞŶnjƵĞůĂ͕ŽƌŽƚŚĠĞDŝƐƐĠͲŚĂŝƌƐ 11.15 /ŶƚƌŽĚƵĐƟŽŶ
ŽƌŽƚŚĠĞDŝƐƐĠͲ/Z͕DŽŶƚƉĞůůŝĞƌ͕&ƌĂŶĐĞ dŝƚůĞƚŽďĞĐŽŶĮƌŵĞĚ
:ĞƐƵƐ'͘sĂůĞŶnjƵĞůĂͲEĂƟŽŶĂů/ŶƐƟƚƵƚĞƐŽĨ,ĞĂůƚŚ͕ĞƚŚĞƐĚĂ͕h^
^ĞůĞĐƚĞĚƉƌĞƐĞŶƚĂƟŽŶƐĨƌŽŵƐƵďŵŝƩĞĚĂďƐƚƌĂĐƚƐ
12.45 >ƵŶĐŚͬsŝƐŝƚŽĨĞdžŚŝďŝƟŽŶĂƌĞĂ
13.45 ^&/ͲŝŽƐĐŝĞŶĐĞƐdŚĞƐŝƐǁĂƌĚ
FMC SESSION
:ŽĂŶĂ sŝƩĞ Ͳ ŚĂŝƌ 14.00 ůůĞƌŐğŶĞƐƌĞĐŽŵďŝŶĂŶƚƐ;ŵŽůĠĐƵůĂŝƌĞƐͿ
&ĂŶŶLJ>ĞŐƌĂŶĚ;>ŝůůĞͿ dĞƐƚƐĚ͛ŝŵŵƵŶŽůŽŐŝĞĐĞůůƵůĂŝƌĞ WĂƵůZŽƵnjĂŝƌĞ;>LJŽŶͿ ŝĂŐŶŽƐƟĐĚĞƐĂŶŐŝŽĞĚğŵĞƐ ŚƌŝƐƟĂŶƌŽƵĞƚ;'ƌĞŶŽďůĞͿ
^^^/KE ^/ ͳ ^&/
ŽůŽƌĞƐ :ĂƌĂƋƵĞŵĂĚĂ͕ ZŽůĂŶĚ >ŝďůĂƵ Ͳ ŚĂŝƌƐ 14.00 ^ƟŵƵůĂƟŶŐϭϯϳ;ϰͲϭͿĨŽƌĐĂŶĐĞƌƚƌĞĂƚŵĞŶƚ
/ŐŶĂĐŝŽDĞůĞƌŽͲĞŶƚĞƌĨŽƌƉƉůŝĞĚDĞĚŝĐĂůZĞƐĞĂƌĐŚ͕hŶŝǀĞƌƐŝƚLJŽĨEĂǀĂƌƌĂ͕^ƉĂŝŶ
ZĞĚƵŶĚĂŶƚĂŶĚƐƉĞĐŝĂůŝnjĞĚƌŽůĞƐŽĨZĂƐ'dWĂƐĞƐŝŶůLJŵƉŚŽŝĚĚŝīĞƌĞŶƟĂƟŽŶ͕ŚŽŵĞŽƐƚĂƐŝƐĂŶĚŵĂůŝŐŶĂŶƚƚƌĂŶƐĨŽƌŵĂƟŽŶ ĂůďŝŶŽůĂƌĐŽŶͲĞŶƚĞƌĨŽƌDŽůĞĐƵůĂƌŝŽůŽŐLJ^ĞǀĞƌŽKĐŚŽĂ͕DĂĚƌŝĚ͕^ƉĂŝŶ
dŚĞƌŽůĞŽĨĂƌĞŐƵůĂƚĞĚĞŶĚŽƐŽŵĂůƐƚŽƌĂŐĞĐŽŵƉĂƌƚŵĞŶƚŝŶD,ĐůĂƐƐ/ĐƌŽƐƐͲƉƌĞƐĞŶƚĂƟŽŶ WĞƚĞƌǀĂŶŶĚĞƌƚͲ/ŶƐĞƌŵ͕&ĂĐƵůƚĠĚĞDĠĚĞĐŝŶĞEĞĐŬĞƌ͕WĂƌŝƐ͕&ƌĂŶĐĞ
ƵŝůĚŝŶŐƚŚĞƐŝŐŶĂůŝŶŐĐĂƉĂĐŝƚLJŽĨƚŚĞŝŵŵƵŶŽůŽŐŝĐĂůƐLJŶĂƉƐĞďLJƌĞŐƵůĂƚĞĚǀĞƐŝĐůĞƚƌĂĸĐ ŶĚƌğƐůĐŽǀĞƌͲ/ŶƐƟƚƵƚWĂƐƚĞƵƌ͕WĂƌŝƐ͕&ƌĂŶĐĞ
15.30 ŽīĞĞƌĞĂŬͬdžŚŝďŝƟŽŶ
AUTOIMMUNITY
ůŝĂŶĞWŝĂŐŐŝŽ͕KůŝǀŝĞƌŽLJĞƌͲŚĂŝƌƐ 16.30 dŝƚůĞƚŽďĞĐŽŶĮƌŵĞĚ
ŚƌŝƐƟĂŶŽŝƚĂƌĚͲ/ŶƐĞƌŵ͕WĂƌŝƐ͕&ƌĂŶĐĞ ŝƌĞ͗ĨƌŽŵƉĂƟĞŶƚƐƚŽĂŵŽůĞĐƵůĂƌŵĞĐŚĂŶŝƐŵ
ŝĂŶĞDĂƚŚŝƐͲ,ĂƌǀĂƌĚDĞĚŝĐĂů^ĐŚŽŽů͕ŽƐƚŽŶ͕D͕h^
&ƌŽŵ'ƵƚƚŽƌĂŝŶ͗dŚĞ/ŶŝƟĂů^ƚĂŐĞƐŽĨƵƚŽŝŵŵƵŶĞƌĂŝŶŝƐĞĂƐĞ
,ĂƌƚŵƵƚtĞŬĞƌůĞͲDĂdžWůĂŶĐŬ/ŶƐƟƚƵƚĞĨŽƌEĞƵƌŽďŝŽůŽŐLJ͕DĂƌƟŶƐƌŝĞĚ͕'ĞƌŵĂŶLJ
VETERINARY SESSION
Tbd -‐ Chairs 16.30 dŝƚůĞƚŽďĞĐŽŶĮƌŵĞĚ
TBD
dŝƚůĞƚŽďĞĐŽŶĮƌŵĞĚ TBD
^ĞůĞĐƚĞĚƉƌĞƐĞŶƚĂƟŽŶƐĨƌŽŵƐƵďŵŝƩĞĚĂďƐƚƌĂĐƚƐ
PIERRE GRABAR LECTURE
18.00 dŚĞDĂŵŵĂůŝĂŶ^ƚƌĞƐƐ^ĞŶƐŽƌyWϭŝŶ/ŵŵƵŶŝƚLJ
>ĂƵƌŝĞ'ůŝŵĐŚĞƌͲ,ĂƌǀĂƌĚ^ĐŚŽŽůŽĨWƵďůŝĐ,ĞĂůƚŚ͕ŽƐƚŽŶ͕h^
20.00 'ĂůĂŝŶŶĞƌ
Thursday November 10th, 2011 PLENARY SESSION
^^^/KE ^& ͳ ^&/ >>Z'K>K'z /
ŶƚŽŝŶĞ DĂŐŶĂŶ͕ sĂůĠƌŝĞ :ƵůŝĂ Ͳ ŚĂŝƌƐ 08.45 ZĞĐŽŵďŝŶĂŶƚŵŝƚĞĂůůĞƌŐĞŶƐĨŽƌĚŝĂŐŶŽƐŝƐĂŶĚŝŵŵƵŶŽƚŚĞƌĂƉLJ
^ƵnjĂŶŶĞsƌƚĂůĂͲhŶŝǀĞƌƐŝƚLJŽĨsŝĞŶŶĂ͕DĞĚŝĐĂů^ĐŚŽŽů͕ƵƐƚƌŝĂ 09.15 ĞŶĚƌŝƟĐĐĞůůƐŝŶĂƚŽƉŝĐĚŝƐĞĂƐĞƐ͗dǁŽƐŝĚĞƐŽĨŽŶĞĐŽŝŶ͘
dŚŽŵĂƐŝĞďĞƌͲhŶŝǀĞƌƐŝƚLJŽĨŽŶŶ͕'ĞƌŵĂŶLJ
09.45 ^ŬŝŶd^>WŝŶĂůůĞƌŐŝĐŝŵŵƵŶĞƌĞƐƉŽŶƐĞƐ͗ĨƌŽŵĂƚŽƉŝĐĚĞƌŵĂƟƟƐƚŽĂƐƚŚŵĂ
DĞŝ>ŝͲ/ŶƐƟƚƵƚĚĞ'ĠŶĠƟƋƵĞĞƚĚĞŝŽůŽŐŝĞDŽůĠĐƵůĂŝƌĞĞƚĞůůƵůĂŝƌĞ͕^ƚƌĂƐďŽƵƌŐ͕&ƌĂŶĐĞ 10.15 ŽīĞĞƌĞĂŬͬdžŚŝďŝƟŽŶ
10.45 WŽƐƚĞƌƐƐĞƐƐŝŽŶƐ
THEMATICS SESSIONS
^^^/KE ^& ͳ ^&/ >>Z'K>K'z //
DĂƌĐĂģƌŽŶ͕,ĂŶƐzƐƐĞůͲŚĂŝƌƐ 11.15 /Ő'ƌĞĐĞƉƚŽƌƐŝŶĂůůĞƌŐLJ
DĂƌĐĂģƌŽŶͲ/ŶƐĞƌŵ͕/ŶƐƟƚƵƚWĂƐƚĞƵƌ͕WĂƌŝƐ͕&ƌĂŶĐĞ
^ĞůĞĐƚĞĚƉƌĞƐĞŶƚĂƟŽŶƐĨƌŽŵƐƵďŵŝƩĞĚĂďƐƚƌĂĐƚƐ
Ed/ͳdhDKZ /DDhEKd,ZWz
zŽůĂŶĚĂĚĞsƌŝĞƐ͕EĂĚğŐĞĞƌĐŽǀŝĐŝͲŚĂŝƌƐ
11.15 WůĂƐŵĂĐLJƚŽŝĚĚĞŶĚƌŝƟĐĐĞůůƐ͗/ŵŵƵŶŽŵŽĚƵůĂƚŽƌLJƉƌŽƉĞƌƟĞƐĂŶĚƚŚĞƌĂƉĞƵƟĐĂƉƉůŝĐĂƟŽŶŝŶŵĞůĂŶŽŵĂƉĂƟĞŶƚƐ zŽůĂŶĚĂĚĞsƌŝĞƐͲZĂĚďŽƵĚhŶŝǀĞƌƐŝƚLJ͕EŝũŵĞŐĞŶ͕dŚĞEĞƚŚĞƌůĂŶĚƐ
ĂƌůLJdĐĞůůƐŝŐŶĂůůŝŶŐŝƐƌĞǀĞƌƐŝďůLJĂůƚĞƌĞĚŝŶWϭнƚƵŵŽƌͲŝŶĮůƚƌĂƟŶŐůLJŵƉŚŽĐLJƚĞƐ͗ŚŽǁĐŽƵůĚƚŚĞŝŵŵƵŶĞƐLJƐƚĞŵĐŽŶƚƌŝďƵƚĞƚŽƚƵŵŽƌƌĞŐƌĞƐƐŝŽŶ͍
EĂĚğŐĞĞƌĐŽǀŝĐŝͲ/ŶƐĞƌŵhϱϲϳ͕,ƀƉŝƚĂůŽĐŚŝŶ͕WĂƌŝƐ͕&ƌĂŶĐĞ
^ĞůĞĐƚĞĚƉƌĞƐĞŶƚĂƟŽŶƐĨƌŽŵƐƵďŵŝƩĞĚĂďƐƚƌĂĐƚƐ
MUCOSAL IMMUNITY
EĂĚŝŶĞĞƌĨͲĞŶƐƵƐƐĂŶ͕WĂƚƌŝĐŬƌĞƐƚͲŚĂŝƌƐ 11.15 dŝƚůĞƚŽďĞĐŽŶĮƌŵĞĚ
EĂĚŝŶĞĞƌĨͲĞŶƐƵƐƐĂŶͲ/ŶƐĞƌŵ͕&ĂĐƵůƚĠĚĞDĠĚĞĐŝŶĞEĞĐŬĞƌ͕WĂƌŝƐ͕&ƌĂŶĐĞ dŝƚůĞƚŽďĞĐŽŶĮƌŵĞĚ
WĂƚƌŝĐŬƌĞƐƚʹ/ŶƐĞƌŵZ/ͲϮϭ͕ϰϯϭϵ͕EŝĐĞ͕&ƌĂŶĐĞ
^ĞůĞĐƚĞĚƉƌĞƐĞŶƚĂƟŽŶƐĨƌŽŵƐƵďŵŝƩĞĚĂďƐƚƌĂĐƚƐ
12.45 >ƵŶĐŚͬsŝƐŝƚŽĨĞdžŚŝďŝƟŽŶĂƌĞĂ
13.45 >&Ͳ^&/:ĂĐƋƵĞƐKƵĚŝŶǁĂƌĚ
:ĞĂŶͲ&ƌĂŶĕŽŝƐWƌŽƐƚ͕ZŽůĂŶĚ>ŝďůĂƵͲŚĂŝƌƐ
PLENARY SESSION Ed/ͳdhDKZ /DDhE/dz
:ĞĂŶͲ>ƵĐ dĞŝůůĂƵĚ͕ dďĚ Ͳ ŚĂŝƌƐ 14.15 dŝƚůĞƚŽďĞĐŽŶĮƌŵĞĚ
ĂŶŝůĂsĂůŵŽƌŝͲ/ŶƐĞƌŵ͕/ŶƐƟƚƵƚĚĞZĞĐŚĞƌĐŚĞdŚĠƌĂƉĞƵƟƋƵĞ͕EĂŶƚĞƐ͕&ƌĂŶĐĞ
^ƚĂƚĞŽĨĂƌƚŽĨƚŚĞƌĂƉĞƵƟĐǀĂĐĐŝŶĂƟŽŶŝŶƉĂƟĞŶƚƐǁŝƚŚǀŝƌĂůĂŶĚŶŽŶͲǀŝƌĂůĐĂŶĐĞƌ ŽƌŶĞůŝƐDĞůŝĞĨͲ>ĞŝĚĞŶhŶŝǀĞƌƐŝƚLJDĞĚŝĐĂůĞŶƚĞƌ͕>ĞŝĚĞŶ͕dŚĞEĞƚŚĞƌůĂŶĚƐ dŝƚůĞƚŽďĞĐŽŶĮƌŵĞĚ
ĂǀŝĚ<ůĂƚnjŵĂŶŶͲhŶŝǀĞƌƐŝƚĠWŝĞƌƌĞĞƚDĂƌŝĞƵƌŝĞ͕,ƀƉŝƚĂů>ĂWŝƟĠͲ^ĂůƉĠƚƌŝğƌĞ͕WĂƌŝƐ͕&ƌĂŶĐĞ 15.45 ŽīĞĞƌĞĂŬͬdžŚŝďŝƟŽŶͬWŽƐƚĞƌƐĞƐƐŝŽŶƐ
THEMATICS SESSIONS
INNATE IMMUNITY II / MASTOCYTES, GRANULOCYTES
ůĞŵĞŶƐĂŚŝŶĚĞŶ͕EŝĐŽůĂƐŚĂƌůĞƐͲŚĂŝƌƐ 16.30 /ŶŇĂŵŵĂƚŽƌLJĂŶĚŝŵŵƵŶŽƌĞŐƵůĂƚŽƌLJĨƵŶĐƟŽŶƐŽĨŚƵŵĂŶďĂƐŽƉŚŝůŐƌĂŶƵůŽĐLJƚĞƐ
ůĞŵĞŶƐĂŚŝŶĚĞŶͲhŶŝǀĞƌƐŝƚLJ,ŽƐƉŝƚĂůĞƌŶ͕^ǁŝƚnjĞƌůĂŶĚ dŝƚůĞƚŽďĞĐŽŶĮƌŵĞĚ
EŝĐŽůĂƐŚĂƌůĞƐͲ/ŶƐĞƌŵͲϬϮϮϱ͕&ĂĐƵůƚĠĚĞDĠĚĞĐŝŶĞy͘ŝĐŚĂƚ͕WĂƌŝƐ&ƌĂŶĐĞ
^ĞůĞĐƚĞĚƉƌĞƐĞŶƚĂƟŽŶƐĨƌŽŵƐƵďŵŝƩĞĚĂďƐƚƌĂĐƚƐ
CHRONIC VIROSES
ĂŶŝĞů WŝŶƐĐŚĞǁĞƌ͕ EŝĐŽůĂƐ DĂŶĞů Ͳ ŚĂŝƌƐ 16.30 dŝƚůĞƚŽďĞĐŽŶĮƌŵĞĚ
ĂŶŝĞůWŝŶƐĐŚĞǁĞƌͲ&ĂĐƵůƚĠĚĞDĠĚĞĐŝŶĞ͕'ĞŶĞǀĂ͕^ǁŝƚnjĞƌůĂŶĚ ZĞŐƵůĂƟŽŶŽĨƚŚĞŝŶŶĂƚĞŝŵŵƵŶĞƌĞƐƉŽŶƐĞƚŽ,/sͲϭŝŶĚĞŶĚƌŝƟĐĐĞůůƐ EŝĐŽůĂƐDĂŶĞůͲ/ŶƐĞƌŵhϵϯϮ͕/ŶƐƟƚƵƚƵƌŝĞ͕WĂƌŝƐ͕&ƌĂŶĐĞ
^ĞůĞĐƚĞĚƉƌĞƐĞŶƚĂƟŽŶƐĨƌŽŵƐƵďŵŝƩĞĚĂďƐƚƌĂĐƚƐ
RHEUMATOID ARTHRITIS
ŚƌŝƐƟĂŶ:ŽƌŐĞŶƐĞŶ͕:ĞĂŶZŽƵĚŝĞƌͲŚĂŝƌƐ 16.30 /Ő͕WĂŶĚZ͖ŚŽǁĚŽƚŚĞLJĐŽŶŶĞĐƚ͍
ZĞŶĠdŽĞƐͲ>ĞŝĚĞŶhŶŝǀĞƌƐŝƚLJDĞĚŝĐĂůĞŶƚĞƌ͕>ĞŝĚĞŶ͕dŚĞEĞƚŚĞƌůĂŶĚƐ
/ƐƐƵĞƐĂŶĚĐŚĂůůĞŶŐĞƐŝŶƚŚĞƉƌĞĐůŝŶŝĐĂůĂŶĚĐůŝŶŝĐĂůĚĞǀĞůŽƉŵĞŶƚŽĨŵŽŶŽĐůŽŶĂůƐĂŶƟďŽĚŝĞƐ :ĞĂŶZŽƵĚŝĞƌͲ/ŶƐĞƌŵ͕hŶŝǀĞƌƐŝƚĠĚĞůĂDĠĚŝƚĞƌƌĂŶĠĞ͕DĂƌƐĞŝůůĞ͕&ƌĂŶĐĞ
^ĞůĞĐƚĞĚƉƌĞƐĞŶƚĂƟŽŶƐĨƌŽŵƐƵďŵŝƩĞĚĂďƐƚƌĂĐƚƐ
18.00 ^&/Ͳ/ŵŵƵŶ/WŽƐƚĞƌǁĂƌĚ
19.30 ŽĐŬƚĂŝů
