HAL Id: inserm-02135704
https://www.hal.inserm.fr/inserm-02135704
Submitted on 21 May 2019
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Hypoxia leads to decreased autophosphorylation of the MET receptor but promotes its resistance to tyrosine
kinase inhibitors
Meriem Mekki, Alexandra Mougel, Audrey Vinchent, Charlotte Paquet, Marie-Christine Copin, Catherine Leroy, Zoulika Kherrouche, Jean-Paul
Bonte, Oleg Melnyk, Jérôme Vicogne, et al.
To cite this version:
Meriem Mekki, Alexandra Mougel, Audrey Vinchent, Charlotte Paquet, Marie-Christine Copin, et al.. Hypoxia leads to decreased autophosphorylation of the MET receptor but promotes its resis- tance to tyrosine kinase inhibitors. Oncotarget, Impact journals, 2018, 9 (43), pp.27039 - 27058.
�10.18632/oncotarget.25472�. �inserm-02135704�
Hypoxia leads to decreased autophosphorylation of the MET receptor but promotes its resistance to tyrosine kinase inhibitors
Meriem Sarah Mekki
1, Alexandra Mougel
2, Audrey Vinchent
1, Charlotte Paquet
1, Marie-Christine Copin
1,3, Catherine Leroy
1, Zoulika Kherrouche
1, Jean-Paul Bonte
4, Oleg Melnyk
2, Jérôme Vicogne
2and David Tulasne
11
University Lille, CNRS, Institut Pasteur de Lille, UMR 8161 - M3T – Mechanisms of Tumorigenesis and Target Therapies, F-59000 Lille, France
2
University of Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 8204 - CIIL -Centre d'Infection et d'Immunité de Lille, F-59000 Lille, France
3