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Cefepime is efficacious against penicillin- and quinolone-resistant pneumococci in experimental meningitis

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Academic year: 2021

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Figure 1 shows the kinetics of cefepime after two doses of 100 mg/kg. After the first dose, cefepime peaked at a mean of 8.5 mg/L, declining slowly to 5.2 mg/L 4 h later
Figure 2. Killing rates of cefepime in vitro at concentrations corresponding to 10 MIC (5 mg/L) against a penicillin-resistant strain ( ) and against a penicillin- and quinolone-resistant mutant ( )

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