HAL Id: inserm-00850917
https://www.hal.inserm.fr/inserm-00850917
Submitted on 9 Aug 2013
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The postbinding activity of scavenger receptor class B
type I mediates initiation of hepatitis C virus infection
and viral dissemination.
Muhammad Zahid, Marine Turek, Fei Xiao, Viet Loan Dao Thi, Maryse
Guérin, Isabel Fofana, Philippe Bachellier, John Thompson, Leen Delang,
Johan Neyts, et al.
To cite this version:
Muhammad Zahid, Marine Turek, Fei Xiao, Viet Loan Dao Thi, Maryse Guérin, et al.. The post-binding activity of scavenger receptor class B type I mediates initiation of hepatitis C virus infection and viral dissemination.. Hepatology, Wiley-Blackwell, 2013, 57 (2), pp.492-504. �10.1002/hep.26097�. �inserm-00850917�
Figure 3
QQ-4G9-A6 CTRL % I n fe c te d t a rg e t c e ll s QQ-2A10-A5A.
B.
6 7 8 ( L o g1 0 R L U ) CTRL IgG CTRL 1 µg/mL 10 µg/mL 100 µg/mLC.
D.
0 5 10 15 20 25 30*
*
*
*
1 2 3 4 F o ld o f e x p re s s io n 0 10 20 30 40 50 60 CTRL mSRBI hSRBI % I n fe c te d ta rg e t c e ll s 6 7 CTRL CTRL IgG 1 µg/mL 10 µg/mL 100 µg/mL ( L o g1 0 R L U ) 3 4 5 6 0 2 4 6 8 10 12 14 Postinfection (days) H C V c c in fe c ti o n ( L 100 µg/mLF.
E.
QQ-4G9-A6Ctrl IgG Ctrl IgG NK-8H5-E3
3 4 5 0 2 4 6 8 10 12 14 100 µg/mL Postinfection (days) H C V c c in fe c ti o n ( L 50 µm 50 µm 50 µm 50 µm
