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Bullous cutaneous reactions
Mohamed Jira1,&, Taoufik Amezyane1
1Internal Medicine Department, Mohammed V Military Teaching Hospital, Rabat, Morocco
&Corresponding author: Mohamed Jira, Internal Medicine Department, Mohammed V Military Teaching Hospital, Rabat, Morocco
Key words: Allopurinol hypersensitivity, bullous cataneous reactions Received: 19/07/2018 - Accepted: 24/09/2018 - Published: 16/11/2018
Pan African Medical Journal. 2018;31:188. doi:10.11604/pamj.2018.31.188.16608 This article is available online at: http://www.panafrican-med-journal.com/content/article/31/188/full/
© Mohamed Jira et al. The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Allopurinol (xanthine oxidase inhibitor) is indicated for the treatment of symptomatic hyperuricemia, the treatment of gout and the treatment and prevention of uric and calcium lithiasis. It is one of the leading drugs for severe toxic dermal reactions, such as Lyell Syndrome (NET), Stevens-Johnson Syndrome (SJS) and Dress
Syndrome (Drug reaction with eosinophilia and systemic symptoms).
We report the case of a 45-year-old woman who was hospitalized for bullous skin rashes, without pathological history, the patient had generalized erythematous and bullous rash (A, B and C) one week after taking allopurinol, prescribed by his rheumatologist for a gout.
The diagnosis of bullous Cutaneous reaction due to allopurinol was retained, allopurinol was discontinued and the course was favorable with the disappearance of cutaneous lesions.
Pan African Medical Journal – ISSN: 1937- 8688 (www.panafrican-med-journal.com)
Published in partnership with the African Field Epidemiology Network (AFENET). (www.afenet.net)
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Page number not for citation purposes 2 Figure 1: A) bullous cutaneous reaction of the hand; B) bullous cutaneous
reaction of the leg; C) bullous cutaneous reaction of the foot
