• Aucun résultat trouvé

Rôle de la molécule CD47 sur le lymphocyte T dans la régulation de la réponse immunitaire

N/A
N/A
Protected

Academic year: 2021

Partager "Rôle de la molécule CD47 sur le lymphocyte T dans la régulation de la réponse immunitaire"

Copied!
269
0
0

Texte intégral

(1)

(2) 

(3)    .  

(4)   

(5)         .   .   

(6)     

(7) 

(8) .       

(9)  

(10)     

(11)    

(12)  

(13) 

(14)  !   " #$    . % &''(. )  * &''(.

(15)  

(16)     

(17)  

(18)   . +       ,.  

(19)   

(20)        .     ,  . .     -. 

(21)     ,.  / 0.*  

(22)  1   0 2 *

(23)  

(24)    3. * 1

(25)    4 5

(26)

(27) 

(28) * 

(29)  -.  3 %    * 6  6   +

(30)   *   

(31) 

(32) .

(33)   7.  .

(34) .    . . 8   

(35)  ..           

(36)  . .  

(37)      

(38)            

(39)  2  

(40)   # /        

(41)    

(42) 

(43)  

(44)  ..        9   

(45)     +:;+&<1 =   # /    9 

(46)     9   +:>              

(47)  :/?@ " 

(48) 

(49) 

(50) 

(51)  6.1 

(52)   

(53) 1?   29

(54)   

(55)    +:>$ 

(56) 

(57)  ..   +:;    6A  2     ..   22 # 8 .   

(58)     

(59) 1? 2   2   1 2 

(60)     

(61)     6 # 8  6    ..      

(62)  

(63) 

(64)

(65)                *   

(66) 

(67)  

(68)  31# . /    

(69)     B

(70)  +:>   ..   +:;.

(71)        29

(72)   # 7 22 *   C8D

(73) 2   +:>     

(74)     

(75)   

(76)  . 0

(77)  . ?*  9   C8D 

(78)    6  2

(79)  

(80)  

(81)  . 0

(82)  . &# / 6    

(83)   B

(84)  +:>

(85)   

(86) 

(87) 

(88)      

(89)  . ?  * 2

(90)   

(91)   

(92)       

(93)    +:; #. /      B  

(94)  

(95)  +&E  . 

(96) 22     ?>

(97)  ..   +:; =2  

(98)  .

(99)  C8D# 8    

(100) 

(101) 

(102)   

(103)  

(104)  F81& 

(105)  F/1  

(106) 

(107) 

(108)    

(109)  ..     # . /  

(110) 

(111)  B

(112) 

(113) 6    +:>  +&E. 6      +:;*      

(114)    9 

(115)     9*    

(116)  2   

(117) 22  

(118)    GG +:;#.  

(119)   +:>* +:* +?>&* +&E* F2 * F   

(120)  * F* +    * 8..  *   .   * FH 1* 

(121) * 

(122) 1?* ?* ?>* F81?>* F 01?>*  1?#.                     .

(123) .  

(124)  . /I

(125) .*    2    .   

(126) 

(127)    . . ..      

(128)   2 2   I  

(129) # J   . 0I  I.    

(130)    .     . 2  

(131) .  +:;+&<1  # J I      2  

(132) . 6

(133)    +:>    .    

(134) .  .  :/@?  

(135)  "6.1   

(136)  2 

(137) 1? " $ 2 2  

(138)    2 +:>$ 

(139) 

(140)  .    6 

(141)   . 2   22   # K  

(142) .      2     I   

(143)  12 .    2  6   6  #   2  2  

(144) 

(145)  .   I   1

(146) 

(147)  

(148) 311

(149) 

(150)  # . K

(151)   2 

(152)      2 +:> 6     .  12    # J    +:>1

(153) 2 C8D 

(154) .

(155)  ?1

(156)  

(157) . 

(158) . 0 *  

(159) 2  & . 0 2 

(160)   

(161) C8D # K  

(162) .     2 +:>   21     .   . ?  

(163)    

(164)    . 2       

(165)  I   +:;  # . J      1+&E   

(166) . 

(167)  .

(168) 22   2 = +:;    

(169) 2 C8D    F81?>1

(170)   .    F81& 

(171) F/1L1

(172) 

(173)   

(174) 

(175)  2   2  .  # .

(176) . K  

(177)     2  2 I  . +:> 

(178) +&E 6

(179) . +:;      

(180)    

(181) # .  .        

(182)  

(183)  2   

(184)   

(185)   2  *    2 2  

(186) 

(187) 22   2    # . ! "  +:>* +:* +?>&* +&E* F2 * F.* F   

(188)  *  * H .  *   .   * FH 1 * 

(189) * 

(190) 1?* ?* ?>* F81?>* F 01?>*  1?#.

(191) .   #. H  MMMMMMMMMMMMMMMMMMMMMM#MMMMMMMMMM. C  MMMMMMMMMMMMMMMMMMMM#MMMMMMMMMMMM. 

(192)   MMMMMMMMMMMMMMMMM#MMMMMMMMMM##. 8 

(193)  6MMMMMMMMMMMMMMMMMMMMMM#MMMM###M#6. 8 

(194)  2MMMMMMMMMMMMMMMMMMMMMMMMMMMM##6. 8 

(195)    MMMMMMMMMMMMMMMMMMMMMMMMMM#6. 

(196) MMMMMMMMMMMMMMMMMMMMMMMMMMMMM#MM#6. H MMMMMMMMMMMMMMMMMM##MMMMMMM#MMM6. C 1MMMMMMMMMMMMMMMMMMMMMMMMMMMMM6. F 

(197)  MMMMMMMMM#MMMMMMMMMMMMMMMMMMM##MM?. ?# 8 

(198)        MMM##MMMMMMMMMMMMM#MM##?. ?#?# 8 

(199)  ?D5&MMMMMMMMM##MMMMMMMMMMM###MMM#?. ?#?#?#  

(200)  + ?  &MMM##MMMMMMMMMMMM#MMM?. ?#?#&# H  

(201)  

(202) 22   ?MMM##MMMMMMMMMMMMMM#M&. ?#?#N# H  

(203)  

(204) 22   &MMM##MMMMMMMMMMMM#MMM<. ?#&# 8   ?>MMMMMMMMMMMMMMMMMMMMMMM##MMM###E. ?#&#? + 

(205)  

(206)  

(207)  ?D& 

(208)  

(209)   ?>MM##MM###E. ?#&#&# H  

(210)  

(211) 22   ?> O  MMMMMMMMM##MM##?'. ?#&#N# H  

(212) 

(213) 22   ?> O MMMMMMMMMMMM###?&. ?#N# 8 ..     MMMMMMMMMMMMMMMMM#MMM###?<. ?#N#?#   

(214)  ..      "$ MMMMMMMMM##MMM?<. ?#N#&# 8 ..        "$    

(215)   .#MMM###?P. ?#N#N# 6N  B 

(216) 22    

(217) 

(218)  ..     MMMMMMMMMMMMMMMMMMMMMMMMMMMMM###M?>.

(219) . ?#N#:# + B

(220)   2 

(221)    6NMMMM#MMMMMMMMM##M###?E. ?#N#<# 8 ..      

(222)         

(223)  ..   =2 "$ MMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMM#?(. ?#N#P# 

(224)  1

(225)   

(226)     ..     MMMMMMMMMMMMMMMMMMMMMMMMMMMMMM###&:. 

(227)  MMMMMMMMMMMMMMMMMMMM############MM#&<   

(228) 

(229) MMMMMMMMMMMMMMMMMMM#MMM#&<. + MMMM###M#M&P . MMMMMMMM##########MM###&>. ?#:#  

(230)  

(231)  ..      9MMMMM###MMMM##M&(. &#+:>MMMMMMM#MMMM###MMM###MMMMMMMMMMMMMMMM#N&. &#?# 8   +:>MMMMMMMM#MMMMMMMMMMMM##MMMMMN&. &#&# 8

(232)  

(233)  +:>MMMMMMMMMMMMMMMMMMMMM#MMN:. &#&#?# 8 

(234) 1?  & " 1?* &$    " 1N* :* <$MMMMMMMN:. &#&#&# FH "  .  .  MMMMMMMMMMMMMMM##:? . !"#$MMMMMMMMMMMMMMMMMMMMMMMMMMMMMMM:?.  !"#$MMMMMMMMMMMMMMMMMMMMMMMMMMMMMM#M::. &#&#N# +:>    6  , QN* QFFN* Q:?* Q<?  &?MMM###::. &#N#  

(235)    MMMMMMMMMMMMMMMMMM#M:P. &#N#?#       " $ MMMMMMMMMMM#M#M:P. &#N#&#        MMMMMMMMMMMMM###MMMM#M:>. &#N#&#?# 8  +:>  MMMMMMMMMMMMMMMMMMMMM#M#:>. &#N#&#&# 8  +:> FH 1MMMMMMMMMMMMMMMMM###MMM#:E  C  %

(236) %&'MMM#MMMMMM######:E  .

(237) 6   (' ) &   * *  * $*   +   '

(238) MMMMMMMMMMMMMMMMMMMMMMMMMM###M##MM:( . (')'

(239) MMMMMMMMM##MMMMMM##MMM<'. &#N#&#N# 8  +:>DNMMMMMMMMMMMMMMMMMMMM##MM##<?. (

(240) %,%('MMMM###MMMM##MM###MMMMMM<?. &#N#N#  

(241)      

(242)  .  MMMM#MMMMMMMMM<?. &#N#N#?# 8  +:>  FH 1 FH 1#MMMMMMMMMMMMMMMMM###<& .  

(243) MMMMMMMMMMM#MMMMMMMMM<&   ,MMMMMMMMMMMMMMMMMMMMMMMMMMM####M<N . &

(244) 

(245) MMMMMMMMMMMMMMMMMMMM#MMMMMM<<. &#N#:#       

(246)   MMMMMMMMMMMMM###MMM<P. &#N#:#?# 8  +:> 1  1?MMMMMMMMMMMMMMMMMMMMMM<P. &#N#:#&# 8  +:> 1 FH 1 FH 1#########################################################################<E. H   MMMMMMMMMMMMMM###MMMMMMMMMMMMMMM#M##<(. ?# C  FMMMMMMMMMMMM##MMM#MMMMMMMMMMMMMMM<(. &# C  FFMMMMMMMMMMMMMM###M###MMMMMMMMMMMMMM('. N# C  FFFMMMMMMMMMM#MMMM##MMMMMMMMMMMMMMM?NP.    MMMMMMMMMMMMMM##MMMMMMMMM##?>?. ?# F 

(247)  MMMMMMMMMMMMMMMM###MMMMMMMMMMMM?>?. &# +:>   

(248) 

(249)  ?MMMMMMMM###MMMMMMMM?>?. N# +&E   

(250) 

(251)  ?>MMMMMM#MMMMMMMMMM?>>. :# +:>  

(252)  

(253)      MMMMMMMMMMMMMMMM?>(. <# 

(254) 1?D31, 2 

(255) 

(256)    

(257) 

(258)  

(259)  +:>M####?E'. P# +:>  C MMMMMMMMMMMMMMMMMMMMMMMMM#M?EP.

(260) 6 ># 9   C8D

(261) 2   +:> 

(262)  1 

(263)  

(264)   1  2     RMMMMMMMMMMM#?EE. >#?# HB

(265)  F/1MMMMMMMMMMMMMMMMMMMMMM###MMMM?EE  >#&# HB

(266)  F81?'MMMMMMMMMMMMMMMMMMMMMMM###MMM?E(. >#N# HB

(267)  6.

(268)   9 "/K$ MMMMMMMMMMMMM##MMMMMMM?('. >#:# HB

(269)   ?  ?>

(270)   1  29

(271) MMMM?(&  >#<# HB

(272)   ?  ?>

(273)   1 . 9MMMMMMM##?(:. E#  MMMMMMMMMMMMMMMMMMMMMMMMM###MMM?(< . -. /0

(274) 

(275)  /12##############?(<   -2

(276) $. /0  34

(277) 5650MMMMMMMMMMMMMMMMMMMM##?(> . ". /0 34 41MMMMMMMMMMMMM#?(E .  +'7MMMMMM##MM?((. (# +   MMMM#MMMMMMMMMMMMMMM##MMMMM&''. MM#######################################################################################MMMMM##&'?.               .

(278) 6. $  %.    &# 4 

(279)         

(280) 

(281)  .

(282)       +:;+&<;   

(283)        +:;+&<1MMMMMMMMMM&&    '# 8 

(284)   9

(285) 

(286) 22  

(287) 

(288)    1? .

(289)  2  MMMMMMMMMMMMMMMMMMMMMMM###MMMMMMMM#N(.                             .

(290) 6. $( .  )  &* +. 0  2 

(291)      

(292) 22    ?  &MMMMMMMMMMMMMMM##MMMMMMMMMMMMMMMMMM##N  ) '* HB

(293)  / 

(294)  

(295) 22    ?  &MMMMMMMMMMMM#>  )  +* +. 0  2 

(296)      

(297) 22   

(298)    6N;  ?> O  MMMMMMMMMMMMMMMMMMMM###?N. ) * K 

(299)      

(300)   .     MM###&?. ) ,* +. 0  2 

(301)      

(302) 22  

(303)    +:;MMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMM&E. )  -*      9

(304)  

(305)  2 

(306)    

(307)  

(308) 22  

(309)  ..   +:;MMMMMMMMMMMM##MMMMMM##N'. )  *   

(310)     +:>    

(311) 22   

(312)         3  . 9MMMMMMMMMMMMMMMMMMMMMMMNN. ) .*      9

(313)   

(314) 1?  &MMMMM#MM#MM###NP. ) /*      9

(315)  FH 1  FH 1   +:>MMM#################:&  ) &0* HB

(316)  +:> 

(317)   

(318) 

(319)    

(320)    MM#M##?(P. . ) 

(321) 1* . )  &* F

(322)   2  D   . +:>D   MMMMMMMMMMMMMMMMMMMMMMMMMMMMMM##>E. ) '* +  1

(323) 

(324)   311

(325) 

(326)    . 2  

(327)  2 F81&MMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMMM##E'. ) +*C  

(328)  . 2  

(329) 6 2 89MMMMMMM#M###ME&  )  * 8  2   

(330)  .   +:;+&<S  

(331) .     89;  .  MMMMMMMMMMMMMMMMM#MMM###E< . ) 

(332) 11* . ) &* +:>     .   ?

(333)  MMMM#M??P. ) '* +:>

(334) 2. 2 ?

(335) 22   $MMMM###MMMMM##??E.

(336) 6 )  +* F 2 +:>1

(337) 2     +:;   MMMMMMMMMMMMMMMMMMMMMMMMMMMM###MM?&'. )  * +:>

(338) 2.  + 

(339)    F81?&* F/1 

(340) 1 6MMMMMMMMMMMM##MMMMMMMMMMMMMMMMMM?&&. ) ,* C 2 +:>  +:;   2 ? O  MMM##?&:. ) -* ?1

(341)  

(342) . 2  +:>1D1 MMMMMMMM###MMMM#?&P. )  * 7

(343) C12 ?  I    1 

(344) 2    +:>1D1 MMMMMMMMMMMMMMMMMMMMMMM###M##?&E. ) .* 76 

(345) /1

(346) 

(347) +5   +:>1D1 MM###MMMM?N' . ) 

(348) 111*.  )  &* +&E 1         2 F81?> 

(349)  +:;  MMMMMMMMMMMMMMMMMMMMMMM#MMMMMMMMM###?<<. ) '* +&E 1  

(350) 

(351)  

(352)   . ?> MMMMMMM#?<>. )  +* +H 

(353)  . 

(354) +&E 1      ?>

(355)  MMMMMMMMMMMMMMMMM#MMMMMM###MMMMM##?<(. ) *  +&E1

(356)    2 ?>

(357) 22    

(358)  

(359) . F81 & 

(360) F/1 

(361)  MMMMMMMMMMMMMMMMMMMM#MMMMMM##M?P?. ) ,* F  2 ?>

(362) 22   .  1+&E C    

(363) I   6 2 6N;  MMMMMMMMMMMMMMM###MMMM###MMM?PN . ) -*    + 22 .  ?>

(364) 22  MMMM###M#M##?P<. ) * +8C:1F 2 ?>

(365)  MMMMMM##M###MMMMMMM?P>.         .

(366) 6. $  2  . C/ , C

(367) 

(368) 6. 9 CH , C    =

(369)  C , C   + 5 , +6 -

(370) 5  . + , +  2 22   +, +

(371) 

(372)  9 F ,   

(373) 

(374)  7C7, 7    1 6   5C , 5  F8 , F 0 F , F  , 8..      

(375)   

(376)   2 / , /

(377)  /@ , /  @  , 8..        KTC , K HC3 , H 1    C,  

(378)  

(379)    2   +H , 1   8H ,  0  .

(380) 6. U   * . U *. U 

(381) -

(382) *. U  C*. U  *. U /1.*. U H*.

(383) 6.  

(384)  . U   

(385)  H 

(386)    0 2 * -    .  

(387) 22  

(388)  

(389)     # T  

(390) 

(391)  *   *   

(392)   29 6    *      2*  9      *  .

(393)  

(394)    # %      2

(395)    

(396)       9 .

(397)  

(398)  6  #. U  +1 

(399)  H    3. * - . 

(400)   

(401)       

(402)   2# T *    *       

(403)     9       .

(404)    6     

(405)          # V   

(406)     2

(407)      2  #.     6  / 0.* 4 5

(408)

(409) 

(410) * 3 %.      +

(411)   9    

(412)  

(413)  -  #. U   H* -    6     . 

(414)  9 9  O  

(415)  

(416)  *  9          

(417)    -   #. C 

(418)  /  *        

(419)    . 

(420) 

(421)  #. C 

(422)     9 -    

(423)   *  

(424) .   , /. *  H.

(425) * T V T* W2 C0

(426) * %  * 3  *  0 3 17 * % I* C  * ..

(427) 6 8* +

(428)  * @0 J0*   89*  3 *    /.#.     6  /  C  X H.

(429)   Y . 9  O  #. U  

(430)  + 

(431)  H

(432)  5B  / 1*  

(433) .  , 5 @* F F2* 0 * H +.*.       

(434)  

(435)  

(436) . C

(437)  + 

(438)  H

(439)  +5

(440)  5B  / 1   

(441)  

(442)  #.       

(443)  4 

(444)   *    

(445) .   

(446)  

(447)      6 F   

(448)  H  

(449)  +

(450)    

(451)   9 -     

(452)  # . %   6      Z 

(453)   

(454) 

(455) .

(456) C*  2 @ O

(457) * 2 @

(458)  0. 

(459)    Y   9  O    #.  2

(460)    

(461)     

(462) -

(463)           * . 

(464) *         # . %       * 0* 50* .* /-.* 8.

(465) *. 0* 

(466) * 8

(467) *          #.  2

(468)    

(469)     *   *  

(470)

(471)  *.   *         #.  2

(472)     [        * .        

(473) #. % 

(474)    

(475)       #.

(476) 6. 2  .     6    

(477)     

(478) 9 

(479)   .  #.     * -    6     

(480)  

(481) .         

(482)    +:;+&<1        2 :# %    6 6       

(483)    +:;+&<1 =      +:;+&<1 =   

(484)  

(485) 

(486)   

(487)  

(488)       2 ?     . 

(489)   2 N# . V  

(490)  * -    6  

(491)  2 

(492)  2  .  6  $      2 ? "$ &* N* : "C* +* $  <# %.     6      2 E# %      

(493)  

(494)   #.     * -    6        . 2 ? "C* * +$* &* N* :* <* P "* +* * 7$  > "C* $# %      

(495)  

(496)   #.

(497) 66. *&%%+ &%  :   '% ;        +  

(498)       )'2      <  %   +% 

(499) %%%  %     2          +                %      +       :  % :  % :   % '+*  3  8  4

(500)    ?(((.

(501) ?. 1 

(502)   . &*$4  2     &*&*$ &56'  &*&*&*

(503)   &'. 7          9*    +:; = 2  . 

(504) 22     22 * 9 

(505)     

(506)  

(507)  . 0   2 # C

(508) 

(509)    E'*   2

(510) 

(511) 

(512)  9

(513)  

(514)  ..  *     +22   

(515) 

(516) 

(517) 22  

(518)    +:;* 9  

(519)   

(520)  

(521)       

(522)    

(523)     *   2 

(524)  22   +:; "?$# + 6  6* 

(525)  6        

(526)  2    22  

(527) 6  ,   ? " $  &* 9  

(528) 

(529) 22  

(530)     +:; =2 "&* N$# 8  ? 

(531)   F/1L "F 21L$*  81 "8. 61  \F81& "F 01&$ 9   &       . 0  , F81:* F81<* F81(* F81?'* F81?N  F81&< ":* <$# 8  ?  

(532)            *    2   & 

(533) '  & ;*  

(534)   .  

(535) #    ?   29

(536)  

(537)  ]^  

(538)  

(539)     1*  9  .    1 6   "7C7$* 

(540)    1

(541)  . ? "F$      =

(542)  "CH$# +

(543)  *    -

(544)       

(545)  

(546)  

(547)   ?> 

(548)  B

(549)  F81&N*   

(550)   # 8F/1    2   

(551) 

(552)  # 8F81&  .

(553) . &.     

(554)  

(555)    +:;  +E;  # F *   &  22   

(556)    6 *    *   

(557)  

(558)   

(559)    

(560)    

(561)    

(562)  9# 8F81: 2      .9   

(563)  

(564) F7* F3?   ..   "P$#. &*&*'*   (( 

(565)  &. U   

(566)    

(567)  

(568) 

(569)  9*    

(570) 6.

(571) 22   8H " 0  * 8HN* 8H:* 8H>* 8HE* 8H(  8H??$*  8H   

(572) F/

(573)  . ?*     F/1  

(574)  +:'8*   

(575) 

(576)  F81?&*   

(577) 22   ?      /@ ">* E$# 8

(578)  ? 

(579)    2 

(580)    C? " 

(581)  

(582)    2   ?$* 9        F/1  F81&> 9 

(583)    /@      

(584) F81?&*   +     "($# C?  6 2 

(585)    

(586)   

(587)  +H  Z  . 

(588)  2 

(589)    1 "16 6

(590)   $*    -

(591)  

(592) 22   ? "# ?$ "?'$# 8  1 1

(593) 2   

(594)    22    2       

(595)  . ?*        

(596) 2

(597)  

(598)  

(599) F/1       9   

(600) F81?&   "??$ 

(601)        6   "?&$#.

(602) . .   . . . .  . . . .

(603) . .  . . . .  . .   . .  .

(604).  . . .   .   . . .  .  . .  .   . .  . . . .  .   . . .  . .  . /. !'.%/$#%&,

(605) (%0! $$ " +12 " 1##%1/!("3341  3,. +(% , -%#% )%(#.%( #)(! ('+" " .'(%)  

(606) * %

(607) *.  !" #$%. .  . .    .   .  . . &'(%)  

(608) *. .    .     .    . &'(%)  

(609) *. N.

(610) . :. 1    

(611)   

(612)  

(613) F/1*   

(614)  2 

(615) .   58_ "5&#'10 6$* H6N "H 1 

(616)   2  N$    22  

(617)  3CCN "3CC1

(618)    N$  

(619) 22   ? "?N1?E$# 1  Z  6    

(620)  F81?&H& "F81 ?&  1&$* 9    F81?&H?  2    

(621)  F81?& "# ?$ "?($# . 8F81?& 

(622)     

(623) 

(624)  9   2   .

(625) 

(626)   * 6 2  F81?&H&  1 *  

(627)   . 

(628)  2 

(629)    C: "&'$# 8\F81?&H?*        +:; =*  6    ? 

(630) 

(631)

(632)  2 

(633)    FH? "&?$# C:    

(634)  

(635) F/1    6

(636)  F81?&H& "&&1&:$*    

(637)    B      6

(638)  C? 

(639)  1 * 9  

(640)    .     

(641) F/1 "# ?$ "?P* &:1&>$  .  

(642)       9 F/1      . 

(643)  1 . 9 

(644)  :E  

(645)  

(646) 22   ?* .  9

(647) 

(648)      9

(649)  F81?& "&E$#  * 1  H6N    

(650)  

(651) F81:  

(652) 22   & "?N* ?<$#    2 

(653)   

(654)   2 16* 7

(655)  "7$*     

(656)  

(657) F/1     +E;*   6 

(658)  

(659) 22  

(660)   +:;   ? "&($# 7 22 *   

(661)   ?  F81&?     . 

(662) F/1   

(663) 7*  

(664)  1 "N'$# 8F81?EH   6    

(665)  

(666) 2

(667)  

(668) 22   ?    

(669)  \  

(670)    F81?&DC:*      F/1 "N?* N&$# 7* F81?&  F81?E 2  

(671)  

(672) F/1    ?  

(673) 

(674)  +H "NN$# + .

(675) . <. 

(676)  

(677)  . 0  1

(678) 

(679)    1Y  9 

(680)    

(681)   ?  6   2     ?#.   

(682)   9  

(683)  / 

(684)  

(685) 22    ? "# &$. "N:$# 86

(686)     88 " 10 

(687) $   C +        

(688)  

(689)   *     

(690) 

(691)  

(692) 22    ?   / N   2

(693)     +:;# / N*       H % "/C1

(694)  2   11

(695)    2 1 % $

(696)       C 8? "  

(697) 1 0 ?*  

(698)      . 

(699)  2 

(700)    1 "N<* NP$#      2     /1  "N>$# 8   / 

(701) 

(702)  &      . 

(703) 

(704) 

(705)  

(706) 22    ? "NE$#. &*&*+*   (( 

(707)  '. 8

(708) 22   &        

(709)  

(710)  +H

(711)   . +:;* 9  

(712)    

(713)  

(714)  2 6

(715) F81:* 9 

(716)  6

(717)  3CC1N   

(718) 

(719)    

(720)  2 

(721)    CP "N(1:?$ 

(722)    

(723)  C<  F81& "# ?$ "N* :&$# 3CCN   2 

(724)    

(725) 

(726) 

(727)   &*

(728)  

(729)     2    

(730) 

(731)     

(732)      

(733)

(734)  

(735)  . 0

(736)  . &* 9 

(737)  

(738)  F81:* F81<  F81?N*    

(739)  

(740)  6

(741)  

(742)  F81<  F81?N ":N1:P$*    

(743)   2 

(744)    9 

(745)  

(746)  &

(747)   "N* :>$# 8 1  

(748)  6

(749)  3CCN        

(750)  CP  F81:* .

(751) . P.    

(752)    B  2     CP  3CCN*

(753)  6

(754)  F/1 

(755)  

(756) 22   ?*      & "# ?$ "N* :E$# 8

(757)   

(758)  

(759)  3CC1N

(760)     +:;  Z 

(761) 2

(762) 

(763) 22   &    ":(* <'$# 8 

(764)  F81: 

(765)  * 9    

(766)    B  

(767) 

(768)  

(769)  CP  

(770)     &*  

(771)      +:;+::;*

(772)   +:; = 

(773)  

(774)    *  9   "<?1<N$# 8  CP1

(775) 2   

(776)  

(777) 

(778)  F81:  *  9 *    & 

(779) 

(780)  

(781)    

(782)  CP*  9  22 *     "<:1<P$# . C* F 6      

(783)  

(784) 22    & 

(785) 

(786)  

(787) . CP     

(788)   

(789)  /  "# &$ "<>* <E$#    

(790) 

(791)  & 

(792) 

(793)  

(794)  CP     

(795)   

(796)  F81 &DF81&H1C<C  

(797) 

(798)    . 

(799) F81:*  9 1 

(800)    

(801)    

(802)  F81: ":&* <(* P'$# 8 

(803) 2   C<C  

(804)  

(805) 22    &   *    

(806)  C< ":&* P'$# 8F81:  F81&  

(807)   

(808) 22   

(809)   &  "P'* P?$# . 8 

(810)    F81:DCP     6  .

(811)  321? "3I  2  

(812) 

(813)  1?$*   

(814)    9 2  

(815)   6 2  3CC1N*   

(816)  &  2   "P&* PN$# 8 2 

(817)    1 2 "+    2$ -   B

(818)  6

(819)  F81: "P:* P<$# .

(820) .  )*

(821) ( #$%$ (  (%.   . . !3 ! . . . /

(822) /. 5/5 678. . . /

(823) /.  .  )*  )* #%)(' #%. 8 ++%.  8 ++%.. 5/5 678.

(824). $!* )%

(825) &>.

(826)  %. . 5 / 5  678.  . . . %"$*%# /""%(+;%#

(827) %# 7( # +" .%<. /7. &'(%)  

(828) *. /. !'.%/$#%&,

(829)   (%(%2%:#$$ " +1##%41% ( (3341  ,. +(%,%="%.% )*. #" .'(%)  

(830) * %

(831) *.  !" #$%. & $ % %( )%""" (% .%" #   "+ ..  )*. &  &. /)% )%( : "  ) ) )#" )# 9 #%)(' #% 7!. 6 )'(%#19(#1

(832) . /7. . &'(%)  

(833) *. >.

(834) . E. 86

(835)  FH1:     

(836)  &# 8  FH1:1

(837) 2  

(838)   

(839) F81:* 22 9  Y  

(840)     6

(841)  3CC1N*   9FH1:     6

(842)  3CC1N "PP* P>$#. &*'*$  &  &*'*&*  

(843)       &5'  

(844) 2 

(845)   &. 

(846)   * 

(847) 

(848)    2    1. *  9     9* 

(849)    1

(850)  .1? "F$*        =

(851)  "CH$   

(852)  6  6  2*  .    1 6   "7C7$*      

(853) - *  

(854)          B * 9 6

(855) 22  ?  29

(856)  

(857)  ]^# +

(858)  *  

Références

Documents relatifs

A proposed indirect methodology includes the introduction of an infinite-dimensional transformation that maps the wave equation into a semilinear system of three coupled PDEs,

Unit´e de recherche INRIA Lorraine, Technopˆole de Nancy-Brabois, Campus scientifique, ` NANCY 615 rue du Jardin Botanique, BP 101, 54600 VILLERS LES Unit´e de recherche INRIA

" &!"02/"5-/&*+12+YYYYYYYYYYYYYYYYYYYY|z yYv />-/1&,+!"0 1>/&"0"" 1/, ,*->1"+1"0YYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYY|z yYw

 Ϯ ZĠƐƵŵĠ  &gt;Ğ ŵŝĐƌŽĞŶǀŝƌŽŶŶĞŵĞŶƚ ƚƵŵŽƌĂů͕ Ğƚ ŶŽƚĂŵŵĞŶƚ ůĞ ƐƚƌĞƐƐ ŚLJƉŽdžŝƋƵĞ͕ ũŽƵĞ ƵŶ

However, to our knowledge no previous work has demonstrated a complete toolbox for frequency state engineering through pump spatial tuning, includ- ing a control over the symmetry

Il en résulte que des cellules épithéliales produisent moins de chimiokines en réponse à des EHEC sauvages par rapport à des bactéries invalidées pour les gènes codant pour Stx1

Le premier plan stratégique publié avait pour objectif d’aboutir dans les 10 ans à au moins un essai clinique de phase I utilisant des cellules souches embryonnaires.. Le CIRM

A inclusão de glicerina bruta até 10% na matéria seca em dietas para novilhas, não afetaram as atividades do comportamento ingestivo. Comportamento ingestivo de