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Canine gangrenous mastitis: series of three patients

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S EGYPTIEN, N SHIMIZU, G ROBITEAU, L GUIEU, M LEFEBVRE, S DELEUZE

Department of Clinical Sciences, Clinique Vétérinaire Universitaire, University of Liège, Belgium

3-y old neutered Sheltie

- 36 hours post

ovariohysterectomy on four

dead puppies

- Referred under

amoxicillin-acid clavulanic and enrofloxacin

- At admission :

• severe hypotension • septic decompensated

shock

CANINE GANGRENOUS MASTITIS : SERIES OF THREE

PATIENTS

Common treatments

- Aggressive fluidotherapy

- Continuation of initial antibiotherapy - Progressive debridement

- Bandages: • wet-to-dry

• alginate-honey patches

- Extensive debridement under anaesthesia - Surgical closure of the wound

Gangrenous mastistis

- more prevalent in ruminants while rare in

the bitch

- mostly Staphylococcus aureus (Gram +, Catalase +)

- alpha haemolysin binding to ADAM10 leads to necrosis and gangrene by:

•  pores membrane calcium inflow  acute inflammation  severe edema

• cleavage of E-cadherin

Negative Pressure Wound Therapy

- Indications:

• open wound management • infection control

• stimulating granulation

- Advantages compared to standard bandages:

• increases contraction • shorter closure rate • cost is comparable • only one change

• earlier surgical closure - Complication:

• vacuum loss: surgeon’s experience dependant

Figure 2, day 7:

Negative Pressure

Wound Therapy

device after extensive debridement

Purpose and Diagnosis

To describe and compare the clinical presentations and treatments, of three bitches with fulminant mastitis with gangrenous

involvement.

Figure 1: at presentation:

mammary glands: extremely swollen, not painful

FARAH 2017

Conclusion

Treatment choice depends on :

- Number of mammary glands involved - Shock status

- Evolution of necrosis

2-y old intact Boxer

- 1 month post partum - healthy litter

- Referred under

amoxicillin-acid clavulanic

- At admission : • prostrated

• extremely painful mammary tissue

3-y old intact New Foundland

- 2 weeks post partum (C-section)

- 3 out of 6 puppies passed away within 3 days of birth due to agalactia

- Referred under cefazoline - At admission :

• alert

• hyperthermia

Figure 5: at presentation:

mammary glands: purplish, indurated, painful

Figure 3: at presentation: open

necrotized mammary gland

Figure 4, day 3: After 2

partials debridements. A redon’s drain was placed at surgical closure of the wound

Figure 6, day 7: after

partial debridement and alginate-honey patches

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