Etude phénotypique des cellules endométriosiques profondes

HAL Id: tel-00832636

https://tel.archives-ouvertes.fr/tel-00832636

Submitted on 11 Jun 2013

HAL is a multi-disciplinary open access archive for the deposit and dissemination of sci-entific research documents, whether they are pub-lished or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers.

L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou étrangers, des laboratoires publics ou privés.

Etude phénotypique des cellules endométriosiques

profondes

Mahaut Leconte

To cite this version:

Mahaut Leconte. Etude phénotypique des cellules endométriosiques profondes. Sciences agricoles. Université René Descartes - Paris V, 2012. Français. �NNT : 2012PA05T084�. �tel-00832636�

1

1

1

234541

678917ABCDE91FC19C1C1

2414145241651452451

5ECDC1C1F1EC1CB1C1F15DB 1

234561743849A561B1C3DE71

EE!FEDC1"1#E7F7EC1$7F 8FE9C1CB1CFF8FE9C1

1

1

28F76148EF611

7613655F56167489E4EF61944761

1

1

69 CDB C1CB178BCD8C1!8AFE%8C$CDB1!91

AAF81634861

FC1&1 C$A9C1'()'1

1

1

1

1

F91

697*CC891#C9B9D15542+169 ECDB181,89-1

697*CC891.9  9E1#224/+1E9CBC891C1B01C1

697*CC891,CD209EB7!0C14+1!!79BC891

697*CC89109EB7!0C164+1!!79BC891

697*CC89109FC136+1143$EDBC891

697*CC891.9DE1432+143$EDBC891

1 1

1 1 1

)1

2222 !1

1

,E$C9E1 C3!9E$C91 EE1 B78BC1 F$E9BE7D1 CB1 F**CBE7D1 %8C1 5 !9786C1 !7891 FC1 697*CC891 #C9B9D1 55421 %8E+1 B78B1 CD1 $C1B9D$CBBDB1 7D1 C3! 9ECDC1 0E989EFC+1$1 !979CE6C$CDB11 7D8EBC1 891 F1 67EC1 C1 F1 9C0C90C71 CB1 EDE1 %8C1 5E1  786C9B1 8D1 8B9C1 8DE6C9+1 CF8E1 C1 ECDC71 C1 697*CC891 .9  9E1 #224/1 $-1 1 0FC89C8C$CDB1 8CEFFEC71 F1 CB1 !E7DD 1 !7891 8DC1 B0 $BE%8C1 %8E1 $CB1 019C1 C!8E1 F7DBC$!+1 CB1 $1 7DD 1 FC1 78BEF1 !7891 FC3!F79C91 81 8DC1 8B9C1 0CFFC71CBBC1B0 $BE%8C1CB1FCD7$ B9E7C71,C1FC19C$C9EC1!78911E!7DEAEFEB +17D178BECD1 CB1C17DCEF71

41 9CD7DB9C1 6C1 FCD7$ B9E7C1 BC1 C1 $7D1 EDBC9DB1 81 7891 C1 871 7! 9B7E9C1 CDB9C1 FC1 697*CC891#C9B9D155421CB1FC1697*CC89109FC13671C!8E+15-1E17D9 1$1B01C1C1 $ CEDC1 CB+1 F791 C1 $7D1 FEDEB+1 8D1 !!9CDBEC1 FEDE%8C1 CB1 0E989EF1 !7891 FC%8CF1 FC1 697*CC891 #C9B9D1 55421 CB1 09FC1 361 $7DB1 7DB$$CDB1 8E C71 C1 697*CC891 09FC1361$1*EB17D*EDC1CB15C18E1*E19C18578908E1C19C!978E9C1C18716C1FC17BC891 #98D71 #934541 6C1 %8E1 D781 !9BC7D1 FC1 $:$C1 CDB078E$C71 ,C1 9C$C9EC1 FC1 697*CC891 361!78911 D 97EB 1D1F1B9D$EE7D1C17D167E971

09EBEDC134411C81F1!BECDC1C1$EBC91D1$C1!9C$EC91!71C17BC891CD1ECDC+1 97FC1 +1 $1 7DD 1 C1 FC;7D1 C1 0E989EC1 0C<1 F1 789E1 CB+1 CD1 CFFC+1 5E1 B9786 1 8DC1 $EC71 5D9EDC1 3=4/+1 8578908E1 ED7DB789DAFC1 CD1 $BE19C1 CD7$ B9E7C+1 $1 !8F C1 C1 C9DE19C1DD C1CB1$1!C9$E1C1$CDC9181AECD1C1B96EF71,C1FC19C$C9EC1ED*EDE$CDB71 4D*ED+15E1*EB18DC19CD7DB9C1CCDBECFFC+1CFFC1817BC891#C9D91>41%8E1EB1B9786C91FC1$7B71 1 1 ,C19C$C9EC10FC89C8C$CDB1FC1697*CC89109EB7!0C1641CB1,CD209EB7!0C17?F1%8E1 7DB1C!B 1C19CFE9C1C1B96EF71,C19C$C9EC1FC1697*CC891.9DE14321%8E1$07D79C1CD1C!BDB1 C158C91C1B96EF71 1 6CD C1!9BE8FE19C1!789109EBEDC1.2471 1 1

'1

!"#21

1

 "$% "1 &1 '#( 211 )1  "$% "1**"C#('+%21 )1 ,2$"2 "!21 -1 $2!( "1C22#21$21,2$"2 "!21 -1 4.251 &1 352941 @1 4644941 A1 516241414442541945241 )(1 ('.!"(# '""C21 //1 451234451 ))1 451#5451.442451 )'1 0# 2%!1$21(2$!("! "1 /)1 .24519442B451 )C1 .245144442/1 )&1 .2451469442B451 )@1 2$"2 "!212 1#21 /11 ! # 2C21 '2#(2% +%21 /21 2244421441 )A1 2244421391 '(1 5552414441116421 ')1 2#!2!1$21#1("02# "1 DD1 ! 2!!1"3.$# 1 DD1 4.21 ''1 451445445141621451.44514245141/D9441 'E1 45144544514142/.21451.44514245141/D9441 'F1 4514..4251#34B451451.44514245141/D9441 '@1 524551/D214214442541 'A1 #14"21#!5#05265261 781 4514..42451411414G+145152414214515#52251 E)1 2214114152.244G24G16141524551/D21 EH1 1564.241414G1 EH1 414114152.244G24G1 EC1 52.244G24G1421944541 EC1 52.244G24G1421.4421 EC1 244251234642B451 E&1 1 1

1 1 1 E1 #14"21(765#6 5 "1 711 4514..42451411416EG2G2242+145152414214515#52251 EA1 6EG2G22421421944541 HA1 244251234642B451 F(1 2#!21$%12% 22 1 &D1 134G41/)'1 FE1 41446241/H1 FE1 44544122141141/)'2/H1 FH1 4..4251#9B45141141/)'2/H1 FF1 4245141141/)'2/H1 F&1 123441451445153451445451 F@1 1234414514451534514442451 F@1 444114244421441 FA1 244251234642B451 C'1 '#( 211 )71 $2#'2123(22 #21 )71 $2#'2123(22 #21 )91 # 2212 12 '"$21 )11 64444421451255513451 C@1 4/221441421241 CA1 42414116.421421411#241441 &(1 I241411621451.44514245141/D9441 &(1 I21414/645514514462451/1#J451 &)1 421414621411414G142141141G21 &)1 421414/6455141/H1 &E1 42141149214514451444241426B41 &H1 421411422141/)'142141C15141B416424161451 &H1 421414/6455141K54161>45241#21 &H1 444141 &F1 D54152252B41 &C1 # 21/121 2!"%!1$%212!12!"!1$,2$"2 "!21("0"$21'2:1#1!"%!1 --1 # 21D112!1'* 2%!1$21(" 2216#!21" "2 1#1("C2!!"1$21,2$"2 "!211 181 # 217112002 !1# ("02# 0!1$21,##! ":"2;1$%12 '" 23# 212 1$%1&50%1!%1,2$"2 "!211 171 # 219112002 !1# ("02# 0!1$2!1#C"! 2!1$2!1##*"<$2!1!%1,2$"2 "!21("0"$211 1)1 # 21&1"21$21, 2# "13/D5391$#!1#1('.!"(# '""C21$21,2$"2 "!21("0"$21 121 1 1

H1 '#( 211 /8)1 (2!(2 42!1 /8)1 (2!(2 42!10"$#2 #2!1 /8-1 (2!(2 42!1+%2!1 /8-1 6652114551B41 )(&1 53441414241 )(@1 20222!1**"C#('+%2!1 //)1 1 1 1

1 1 1

F1

 "$% "1

1

CD7$ B9E7C1 CB1 8DC1 $FEC1 *9 %8CDBC1 %8E1 B780C1 @1 81 )(L1 C1 *C$$C1 CD1 MC1 C1 !979 C91)714FFC1CB19C!7DAFC1C178FC891!CF6ECDDC1097DE%8C1CB1ED*C9BEFEB 1CB19C!9 CDBC181C1 BEB9C1 8D1 0DE!1 89AFC1 D1 F1 6EC1 C1 $FC1 6C1 C1 7D %8CDC1 $5C89C1 891 FC891 6EC1 7EFC+1!97*CE7DDCFFC1CB1891FC8916EC1C178!FC+1D17$!BC918DC1BBCEDBC181FC8916EC1C1*C$$C714FFC1 9C!9 CDBC18D1!97AF1$C1C1DB 1!8AFE%8C1BDB1!911*79BC1EDECDC1%8C1!91FC17NB17DE 9AFC1 %8CFFC1CDCD9C1!7891F17E B +1CBE$ 181!F81C1'@((1O1!91EDE6E81CB1!91D183151'71F1DC3EBC181 C15789188D1B9EBC$CDB189BE*1C1F1$FEC1079$E1FC3 91C10E989EFC1C1F E7D71D1FC11 C1 5,67489E461 94476+1 CB1 CD1 !9BE8FEC91 CD1 1 BBCEDBC1 9CBFC+1 F1 0E989EC1 CB1 786CDB1 C3BCDE6C1CB17E C1818DC1$79AEEB 1EDE*EBE6C71C1B9EBC$CDB1$ E8318BEFE 158%881!9 CDB1 9C!7CDB1 891 8DC1 079$7D7B0 9!EC1 6EDB1 81 AF7%8C91 F1 *7DBE7D1 769ECDDC1 7DB1 FC**CB1 DCB1 %8C1 8!CDE*1CB1B9DEB7E9C7117DDEDC1C1$ DE$C181F79EEDC1C1F1$FEC1CD7$ B9E7E%8C1 !979CC1CB1C1 B8C1C3! 9E$CDBFC17DB1786C9B18B9C1!C9!CBE6C1B0 9!C8BE%8C17$$C1FC1 DBE297$BCE2H1CB1FC1DBE273-DB1H71C167EC1C19C0C90C17DB1CD789CDBC+1$E1EF1!C9EBC1 C1 <7DC1 7$A9C1 !0-E7!B07F7E%8C1 C$!:0DB11 !!9 0CDC917$!F1BC$CDB1 FC1 7$!FC3EB 1 AE7F7E%8C1 CB1 FEDE%8C1 C1 CBBC1 $FEC71 4D1 C**CB+1 $:$C1 EF1 C3EBC1 69EC$AFAFC$CDB1 C1 $ DE$C1 $ BA7FE%8C1 7$$8D1 CDB9C1 FC1 E** 9CDB1 B-!C1 CD7$ B9E7C+1 FCD7$ B9E7C1 !97*7DC17DBEB8C18DC1*79$C1DB7$72FEDE%8C181!9B71F1C3EBC181C157891B911!C81C1B96831!79BDB1 ! E*E%8C$CDB1 891 FC1 9B 9EBE%8C1 CFF8FE9C1 C1 FCD7$ B9E7C1 !97*7DC71 DC1 $CEFFC89C11 7$!9 0CDE7D1 C1 $ DE$C1 81 F79EEDC1 C1 FEDEBEBE7D1 CB1 81  6CF7!!C$CDB1 C1 F1 $FEC1 !C9$CBB9EB1 C1 !97!7C91 8D1 B9EBC$CDB1 EAF 1 7DB1 FC1 A8B1 C9EB1 C1 7DB9PFC91 F1 -$!B7$B7F7EC1 78F789C8C1 781 C1 !97!7C91 8DC1 Q19 8BE7D1B8$79FC1R1 81 FE$C1 C1 B9EBC$CDB1 D 72586DB1 D1FC1DC91*ED1C1!C9$CBB9C18DC10E989EC1$7ED1$79AEC717A5CB1C1C1B96EF1CB1 B8EC91FC1 !0 D7B-!C1 C1 CFF8FC1 CD7$ B9E7E%8C1 !97*7DC+1 CD1 !9BE8FEC91 FC891 9B19C1 0-!C9!97FE* 9BE*+1 CD1C3!F79C91FC1$ DE$C1CB1C1FC1C3!F7EBC91*ED1C1BCBC91C1D786CFFC167EC1B0 9!C8BE%8C711 1

1

C1

1

1

1

1

1

1

1

1

'#( 211

 "$% "1**"C#('+%2

1

1

1

1

1 1 ,67489E461

&1

,27489E461

$639E8E41=9A5617615,67489E461

$EE8E41

67489E461C1 *EDEB17$$C1F1!9 CDC1CB7!E%8C1C1BE81CD7$ B9EF1*7DBE7DDCF1CD1 C0791 C1 F1 6EB 1 8B 9EDC+1 EB8 1 81 EBDC1 C1 FCD7$1B9C+1 CB1 D1 7DDC3E7D1 6C1 F8E71 0C<1 FC1 $FC1CD7$ B9E7E%8C+1FCD7$1B9C1EB8 1CD1!7EBE7D1D79$FC1CB1!!CF 1CD7$1B9C1C8B7!E%8C1 CB1 FC1 F E7D1 CD7$ B9E7C1 7DB1  ED C1 781 FC1 D7$1 CD7$1B9C1 CB7!E%8C71 CD7$1B9C1 CB7!E%8C1 9CBC1 CDEAFC1 831 69EBE7D1 079$7DFC1 81 -FC1 $CDB98CF+1 7$$C1 FCD7$1B9C1 C8B7!E%8C71EDE+1F108BC1A98BFC1C1B831!F$BE%8C1SB971DC1CB1C1!97CB 97DC181F1*ED1C1 F1!0C1F8B FC1!9767%8C18DC1C%8$BE7D1C1CFF8FC1 !EB0 FEFC1CB1F1896CD8C18D1EDC$CDB1 8E1 AECD1 D1 FCD7$1B9C1 C8B7!E%8C1 %8C1 D1 FCD7$1B9C1 CB7!E%8C71 C1 EDC$CDB1 %8E1 C1 9C!978EB1 81 0%8C1 ! 9E7C1 $CDB98CFFC1 A78BEB1 81 8DC1 ED*F$$BE7D1 097DE%8C1 7DB1 F1 B98BE7D1 FEDE%8C1 CB1 F1 896CD8C1 C1 78FC891 !CF6ECDDC1 -FE%8C1 81 9C98CCDC1 !C92$CDB98CFFC71 CD7$ B9E7C1 CB1 7DE 9 C1 7$$C1 8DC1 A5A7E61 >E=6;1 394EF6;1 E5AA84E961 681 ?894=45767A861F714FFC1CB19B 9E C1!918DC19DC10 B 97 D EB 1FEDE%8C1CB1DB7$E%8C1 !C9$CBBDB1 C1 EBED8C91 FCD7$ B9E7C1 8!C9*EECFFC+1 FCD7$ B9E7C1 769ECDDC1 CB1 FCD7$ B9E7C1 !97*7DC7167489E461F69E3E655619 FEC1C1E$!FDB1! 9EB7D 8318!C9*EECF1AFD0MB9C1781 AFC8B 1 !9 * 9CDBECFFC$CDB1 F7FE 1 D1 FC1 !CF6E71 CD7$ B9E7C1 769ECDDC1 9 FEC1 C1 T-BC1 769ECD1 CD7$ B9E7E%8C1 781 67489E461 7DB1 FC1 7DBCD81 0 $BE%8C1 CB1 9B 9E 1 !91 1 78FC891Q1077FB1R7167489E461944761ED*EFB9C1F1$88FC8C1C179DC1!CF6ECD1C181!9BE91 8DC1 F E7D1 EDEBEFC1 EB8 C1 CD1 !7EBE7D1 9 B972C96EFC+1 82C81 C1 F1 F7E7D1 9CB726EDFC+1 CD1 9C9181B79818B 9ED1&714FFC1BBCEDB1!91799C1C1*9 %8CDC1 97EDBC1FC1FE$CDB18B 9729 +1 FC18F2C216EDF1!7B 9EC891CB1F1*C1DB 9EC89C1819CB8$1@1U0E=F961/V714D11C1 6CF7!!C$CDB1 FB 9F1 81 D78FC1 D1 FC1 !9$1B9C+1 7D1 !C8B1 7AC96C91 8DC1 1 BBCEDBC1 89 B 9FC1 C3B9ED1%8C1 67E9C1 EDB9ED1%8C1 6C1 8DC1 ED*EFB9BE7D1 C1 F1 $88FC8C+1 9C!7DAFC1 8DC1 89 B 9720-97D !097C71 CD7$ B9E7C16 EFC1!976ECDB1C1FED*EFB9BE7D1CD1!97*7DC8918D1D78FC1CD7$ B9E7E%8C1818F2 C21EDBC926 E728B 9ED71CD7$ B9E7C1!97*7DC1CB18DC1$FEC1F58E43A561B780DB1!F8EC891 79DC181F1*7E1CB1D1F%8CFFC1FC1E** 9CDBC1 *79$C1CD7$ B9E7C1U8!C9*EECFFC+1769ECDDC1CB1 !97*7DCV1!C86CDB17C3EBC91A2))71

@1 1 1 1 1 1 1

11111111111111111111111111111

1

1

'E8454=E61

C1 ED7BE1 CD7$ B9E7 7,F1 E85EF1 761 861 674 !7!8FBE7D1 CFF8FE9C1 !9EDE!FC+ 69EAFC1 81 C1 D7$A9C8C1 CFF8F *EA97C)'2)E71D1C9BED1+18DC1 F E7D1CD7$ B9E7E%8C17DB1F1! DBE2)(+1 9B 9EBE%8C1 C1 CF *79$C1B-!E%8C1)E1U0E=F961DV711 1 1 11111111111111111111111111 1 1 1 1 1 1 1 0 B 97 D EB 1 0EB7F7E%8 FC$CDB1 0C<1 8D1 $:$C1 EDE6E CD7$ B9E7C1!97*7DC1C1 6CF 9E0C1CD1*EA9C1$88FE9C1FEC1 ! E*E%8C+1 C1 F1 *EA97C1 CB1 C F55765A31AA=EA511 489E6F91

7$ B9E7C1 CB1 0EB7F7E%8C1 CB1 9C!7C1 891 5,A43EA8E41 1 67489EA51 AF1 6E1 7,F1 894A1 A651 349E41 3 EDE!FC+1 !EB0 FEFC1 CB1 B97$FC+1 7DB1 7E C1 D C1 CFF8FC1 81 -B1$C1 E$$8DEBE9C1 CB1 ED*F$$B7E9C +18DC1C1C831!7!8FBE7D1CFF8FE9C1!9EDE!FC1 7DB1F1!9BE8F9EB 1:B9C1B9111894=@671D1$9%8 1 C1 CFF8FC1 B97$FC1 CD7$ B9E7E%8C+1 !C8B1 EC91

1

B7F7E%8C1 C1 F E7D1 CD7$ B9E7C1 C3EBC1 8D1 EDE6 C1 EDE6E81 CF7D1 F1 F7FEBE7D1 C1 F E7D71 67891 C3C 1C1 6CF7!!CDB1$579EBE9C$CDB181DE6C81C1EBC1!8 1FEC1)'2)E714FFC17ECDB1C1$DE19C169EAFC1C1F E7 C1 CB1 C1 F E7D1 0-!C9B97!0EC1 $88FE9C1 FEC1 !

E=A681F8945A391

1

0E=F961 DC1 A9FA=61 A8E5$/81 761 365 67489E4EF6C11

7F79BE7D1 A98DC1 U*F10C1 AFD0CV1 81 -B7!F B97$FC1 7DBEB8DB1 FC1 079E7D1 -B71DC1 CDB7 CD7$ B9EFC1 U*F10C1 6C9BCV71123435 67849A5 6B7 CDB43EFA56B4233FA532FD5

1

1

0E=F961 /C1 1 4F61 A=E88A561 7,F1 >A

CD7$ B9E7C1!97*7DC11111111EB8 1CD19C 82C81C1F1F7E7D19CB726EDFC7 1 638F1 43EA8E41 761 =5A761 68B4F1 49E41 384=@671 C1 C831 E C1 D1 C1 !97!79BE7D1 $B7E9C1 EDE1 %881 C1 F1 1*EB1 *8B71EDE+1FC1 1$9%8C1!91FDBE79!1 B1 EC91 81 ED7BE1 C1 8D1 EDE6E81 81 F8B9C1 $E1 91 C3C$!FC+1 FC1 F E7D1 EBC1!869C1CD19EC1CB1 1C1F E7D1CD7$ B9EFC1 FEC1 !!CF C1 Q1D78FC1 761 3655F561 894A561 -B7!F$C1 C1 CFF8FC1 DC1 CDB789DB1 FC1 FDC1 7849A5 6B71 5 C5 ,F1 >AE1 EEC178FC1 B8 1CD19C9181B79818B 9ED+1 EDFC71

1 1 ,67489E461 A1  D7$-7$BC83R1)H1U0E=F9617V71F1!91EFFC8919 C$$CDB1 B 1 9EB18DC18$CDBBE7D1C1F1CDEB 1 C1*EA9C1DC96C8C1D1C1F E7D1!786DB1C3!FE%8C91F1-$!B7$B7F7EC178F789C8C1)F71 1 1 1 1 1

1

1

2E7E454=E61

1

2E7E454=E61

CD7$ B9E7C1 CB1 8DC1 $FEC1 *9 %8CDBC1 CB1 8DE6C9CFFC$CDB1 9 !D8C71 51 !9 6FCDC1 CB1 E**EEFC1 81 6F8C91 C1 *;7D1 !9 EC1 CD1 9E7D1 8D1 ED7BE1 0EB7F7E%8C1 %8E1 DC1 !C8B1 :B9C1 BAFE1 %881 78918DC1SFE77!EC71D1CBE$C1D D$7ED1%8C+1B781B-!C17D*7D8+1CFFC17DC9DC111D1 /8E176166161F=617619439691)7151!9 6FCDC1CB1C1(+F181FL1D1F1!7!8FBE7D1C1*C$$C1 *C9BEFC1 CB1 C1 'F1 81 H(L1 D1 F1 !7!8FBE7D1 C1 *C$$C1 ED*C9BEFC1)C71 51 *9 %8CDC1 C9EB1 !F81 E$!79BDBC10C<1FC1*C$$C1EBE%8C1%8C110C<1FC1*C$$C1*972$ 9EEDC1CB1*9EEDC1)&2)@1EDE1 %8C1D1FC1B 79EC17E7!97*CE7DDCFFC1 FC6 C1)A2'(+1!97AAFC$CDB1CD19E7D18DC1E** 9CDC1 118317ED711CD7$ B9E7C1!97*7DC19C!9 CDBC9EB1'(L1C1CD7$ B9E7C1')7157D17NB1!7891 F17E B 1CB1CBE$ 181!F81C1'@((1O1!91EDE6E81CB1!91D18315+1!7891FDD C1'(('1'71

6C81 C1 *BC891 C1 9E%8C1 ED !CDDB1 7DB1 B 1 ECDBE*E 71 C9BEDC1 9B 9EBE%8C1 81 -FC1 $CDB98CF1 781 C1 F1 6EC1  DEBFC1 7D8EDB1 81 8DC1 0-!C9SB971DEC1 U$ D90C1 !9 7C1 CBW781 $ D7!8C1 B9E6C+1 D8FFE!9EB 1 781 !9C$E19C1 97CC1 B9E6C+1 -FC1 $CDB98CF1 789B+1 0-!C9$ D7990 C+1 $ D799ECV1 !7899ECDB1 C!CDDB1 *679EC91 FC1  6CF7!!C$CDB1 C1 F E7D1 CB7!E%8C)A2'(+1''2'F71D1EDEC1C1$C179!79CF1 FC6 1C$AFC1817DB9E9C1!97B C91C1F1$FEC1)&71 C1 9PFC1 81 BA1 CB1 7DB976C9 +1 C9BEDC1 B8C1 $7DB9DB1 8DC1 E$ED8BE7D1 C1 FEDECDC1 C1 F1 $FEC10C<1FC1*C$$C1C3!7 C1F791%8C18B9C1817DB9E9C1DC1$7DB9CDB188DC1ED*F8CDC1'C71111 0E=F961 7C1 E41 7,67489E461 9638A561 61 E39434E61 48EF6C111

C1 FDC1 CD7$ B9EFC1 UB:BC1 C1 *F10C1 978CV1 7DB1 CDB789 C1 C1 079E7D1 -B71DC1 U*F10C1 6C9BCV1 CB1 C1 *EA97C1 U*F10C1 D7E9CV1 81 CED1 C1 F1 $88FC8C1 9CBFC1 UB:BC1 C1 *F10C1

58DCV7512343567849A56B715C5CDB43EFA56B4233FA5

32FD51

1

)(1

A1A98E3F5E6917615,67489E4617E=68EA61

44=9AE61761A886E8617E=68EA61

CD7$ B9E7C1 ECBE6C1CB1  *EDEC1 !91 8DC1 ED*EFB9BE7D1 CD7$ B9E7E%8C1 C1 F1$88FC8C1 !9E BFC71 51 !9 6FCDC1 8$CDBC1 6C1 F1  6 9EB 1 C1 FBBCEDBC1 !CF6ECDDC1 !786DB1 F791 BBCED9C1 F(L1 D1 FC1 BC1 1 C1 FCEA7FBD5 A74FF4!5 3FA4!5 U.5V1'&2'@71 1 1 !973E$EB 1 C1 F!!9CEF1  DEBF1 $CB1 81 !9C$EC91 !FD1 FC1 BBCEDBC1 9CB72E$7XECDDC1 CB1 EF 727FE%8C1 97EBC71 C1 F7FEBE7D1 9CBFC1 CB1 C1 F1 57DBE7D1 9CB72E$7XECDDC1 7DB1 FC1 !F81 *9 %8CDBC1 UCF+&LV+1 8E6EC1 C1 F7FEBE7D1 E$7XECDDC1 U)&+HLV+1 EF FC1 UH+&LV+1 EF 72YFC1 UH+)LV1 CB1 !!CDE8FE9C1 UC+HLV'A711 D1 F1 $579EB 1 C1 +1 FCD7$ B9E7C1 ECBE6C1 EDB19C1 D1 FC1 9C1 8DC1 $FEC1 CD7$ B9E7E%8C1 !97*7DC+1  619C1 CB1 $8FBE*7FC71 CE1 C3!FE%8C1 %8C1 !9$E1 FC1 BBCEDBC1 ECBE6C+11 FBBCEDBC1 9CBFC1 7EB1 F1 !F81 *9 %8CDBC1 !8E%8CFFC1 !976ECDB1 81  6CF7!!C$CDB1 !7B 9EC891 8D1 D78FC1 CD7$ B9E7E%8C1 !97*7D1&71 4FFC1 CB1 7AC96 C1 D1 )EL1 C1 CD7$ B9E7C1 !97*7DC1 CB1 9C!9 CDBC1FC1BC1FC1!F81 67F8 1C1F1$FEC1'A714FFC1CB17E C1818B9C1F7FEBE7D1!97*7DC1 D1&(L1C11E(1CB1818DC1BBCEDBC1DDC3ECFFC1D1@(L1C11@71C1BBCEDBC1E$7XECDDC1CB1 EF 727FE%8C197EBC17DB1FC1!F81786CDB17E C1818DC1F7FEBE7D19CBFC71D1B96EF19 CDB19 FE 1 D1 FC1 C96EC1 CD1 7FFA79BE7D1 6C1 F %8E!C1 C1 0E989EC1 -D 7F7E%8C1 81 697*CC891 0!97D1 1 $7DB9 1%88DC1BBCEDBC1C1F19 E7D1EF 727FE%8C197EBC1 BEB17AC96 C1D1)@L1C1CD7$ B9E7C1 !97*7DC16C1BBCEDBC19CBFC71C1BBCEDBC1C$AFCDB1:B9C18D1EDEC1C1 6 9EB 1C1F1$FEC714D1 C**CB+1 8DC1 F7FEBE7D1 EF 727FE%8C1 97EBC1 7AC96C1 FC1 !F81 786CDB1 D1 FC1 7DBC3BC1 8DC1 $FEC1 67F8DB1C!8E1!F81C1F1D1CB1CB17E C181C1F E7D1CD7$ B9E7E%8C1!97*7DC1$8FBE!FC1CB1 C1BBCEDBC1ECBE6C1$8FBE*7FC16C1CD1!9BE8FEC918DC1F7FEBE7D1E$7XECDDC1CD1!F81C1F1 F7FEBE7D19CBFC1D1H(L1C11U7$$8DEBE7D179FC1817D911$7DEF1C11FCD7$ B9E7C1 C1C!BC$A9C1'())1V71

!8G61

CD7$ B9E7C1 9CBFC1 !C8B1 :B9C1 9C!7DAFC1 C1 78FC891 !CF6ECDDC1 097DE%8C1 CB1 ED*C9BEFEB 1)+1 E)2E'71 C1 74F56F91 7ECDB1 C1 $DE19C1 69EAFC1 C1 -$!BP$C1 -D 7F7E%8C1 786CDB1 81 !9C$EC91 !FD1 U-$ D7990 C+1 1 -!9C8DEC1 !97*7DC+1 78FC891 !CF6ECDDC1 097DE%8C1 D7D1 -FE%8CV+1 C1 -$!BP$C1 ECBE*1 U7DBE!BE7D1 78F789C8C+1 -0 EC+1 9CB799EC1 !F81 99C$CDBV1CB1C1-$!BP$C1*7DBE7DDCF189EDE9C1819C98CCDC1! 9E2$CDB98CFFC711 $E7F7EC1 C1F178FC891CB1FE C181F1F7FEBE7D1DB7$E%8C1C1F E7D1EE1CB17D1EDBCDEB 1CB1799 F C181FC891 !97*7DC891'A+1 EH71 BBCEDBC1 EF 727FE%8C1 97EBC1 C1 $DE*CBC1 !91 C1 78FC891 $E$DB1 8D1 BAFC81 !!CDE8FE9C17818D1-D97$C1C1G7CDE1B $7EDDB1 8DC1B D7C1ECBE6C19CFBE6C71D1D7B9C1 C3! 9ECDC+1 7$$C1 D1 F1 FEBB 9B89C+1 FC1 ECDB1 7F8E*1 7DB1 C3C!BE7DDCF1 EF71 1

1 1 ,67489E461

))1

-$!B7$B7F7EC1ECBE6C19CBC1C!CDDB1B911!C81! E*E%8C1C1%8E1C3!FE%8C18D19CB91ED7BE1 *9 %8CDB1 EC2E&71 C3EBCDC1 8DC1 CD7$ B9E7C1 !CF6ECDDC1 !97*7DC1 -$!B7$BE%8C1 7EB1 -B $BE%8C$CDB1*E9C19C0C90C918DC1BBCEDBC1ECBE6C1781897F7E%8C17E C+1C18BDB1%8EF1-1 18DC1BBCEDBC1DDC3ECFFC17E C1E@714D11BBCEDBC1E$7XECDDC1781EF 727FE%8C197EBC1FC3$CD1 FEDE%8C1CB1!869C714D19C6D0C1F79%8C1FC19CB8$1 CB1BBCEDB+1EF1EB1FC1!F81786CDB18DC1F E7D1 782! 9EB7D FC1 CEAFC1 81 FC3$CD1 FEDE%8C71 C1 B780C91 9CBF1 $CB1 CD1 6ECDC1 8DC1 $C1 CD0M C1D1F1!97E19CBFC1DB 9EC89C1CB19C!CBDB1F1$8%8C8C71C19 6CEF1C178FC891F791C1 F1!F!BE7D1!!8- C1C1F1F E7D1CB18D198$CDB1CD1*6C89181ED7BE71C3$CD1781DCB0 EC1  D 9FC1CB1C1$CEFFC89C1CDEAEFEB 1EA2H(1CB17EB17EC918D1B780C916EDF+18D1B780C919CBF1CB18D1 B780C917$AED 71

4D1C1%8E17DC9DC1FE698E5E8+1EF1CB1FE%8C$CDB1$E1%8C1'F181F(L1C1*C$$C1ED*C9BEFC1 7DB18DC1CD7$ B9E7C1CB1%8C1'F181F(L1C1$FC1CD7$ B9E7E%8C17DB1ED*C9BEFC1H)71ED*C9BEFEB 1 C9EB1 C7DE9C1 81 UEV1 8DC1 FB 9BE7D1 C1 F1 9 C96C1 769ECDDC1 CD1 *7FFE8FC+1 UEEV1 FBBCEDBC1 C1 FCD7$1B9C1 C8B7!E%8C1 9C!7DAFC1 8D1  *8B1 E$!FDBBE7D1 CB1 UEEEV1 FED*F$$BE7D1 !CF6ECDDC1 EDBC9* 9DB1 6C1 F1 * 7DBE7D1 DB89CFFC1E'71 1 F1 DC3EBC1 88D1 !9FF FE$C1 DB7$72FEDE%8C1 CDB9C1 F BCD8C1C1F1$FEC+11FEDBCDEB 1C1-$!BP$C1CB1FED*C9BEFEB 711

(E4A8454=E61

61849E611

6F8EC891 B0 79EC1 BCDBCDB1 C3!FE%8C91 F1 896CD8C1 C1 FCD7$ B9E7C71 C!CDDB+1 88DC1 DC3!FE%8C1 81 CFFC1 C8FC1 FCDC$AFC1 C1 *79$C1 FEDE%8C1 DE1 DC1 !C9$CB1 C1 9CD9C1 7$!F1BC$CDB1 7$!BC1C1F0 B 97 D EB 1!0 D7B-!E%8C1CB10EB7F7E%8C1C1F1$FEC711

1849E617615,E5A8A8E41 9EBC1!91,70D1715$!7D1D1FC1DD C1)A'(19C!7C1891FC19C*F831 $CDB98CF1%8E1896ECDB1C1*;7D1!0-E7F7E%8C10C<1@(181A(L1C1*C$$C71C1CFF8FC1CD7$ B9EFC1 %8E19C*F8CDB1D1F16EB 1! 9EB7D FC181B96C91C1B97$!C1F791C191FC+1DC17DB1!1 FE$ED C1 !91FC1-B1$C1E$$8DEBE9C+1!97FE*19CDB+1CB1%8E19CDB1C1!97!9E B 10 E7D+1E$!FDBBE7D1CB1 ED6E7D1 H'71 CBBC1 B0 79EC+1 C3!FE%8C1 F1 9 !9BEBE7D1 DB7$E%8C1 -$ B9E%8C1 C1 F E7D1 CD7$ B9E7C71 CFFC2E1 CB1 CD1 C**CB1 1 F%8 C1 891 F1 B7!79!0EC1 C1 9 89EBBE7D1 $CDB98CFFC+1 ED*F8CD C1 !91 F1 !CDBC891 CB1 FDB7$EC1 !CF6ECDDC71 C1 F E7D1 !CF6ECDDC1 7DB1 8DC1 !9 7$EDDC1 DB 9EC89C1 CB1 80C1HE71 81 DE6C81 A7$EDF+1 FC1 <7DC1 C1 BDBE7D1 81 FE%8EC1 ! 9EB7D F1  BC9$EDCDB1 FC$CDB18DC1-$ B9EC1C1F E7D1CD7$ B9E7E%8C1%8E+181FED6C9C+1!9 7$EDCDB181 97EBC1 HH2HF71 1 CBBC1 !7%8C+1 5$!7D1 67%8EB1  581 F1 !7EAEFEB 1 8D1 !0 D7$1DC1 C1 Q1$8FF 9ED7C1R1 799C!7DDB1 81 FED79!79BE7D1 C1 9 E81 CD7$ B9E831 !91 E** 9CDB1 BE81 81

)'1

7891C1F79D7 D1C1HC71CBBC1B0 79EC11!F819 C$$CDB1 B 1 B- C1!918DC1 B8C1%8E19!!79BC1F1 !9 CDC1 E$!FDB1 CD7$ B9E831 891 C1 8B7!EC1 C1 *SB81 81 DE6C81 C1 EBC1 0AEB8CFFC$CDB11 7DC9D 1 !91 FCD7$ B9E7C1H&71 1 849E61 761 5A1 8A5AE61 CF7D1 F%8CFFC1 8D1 BE81 !C8B1 C1 B9D*79$C91CD18D18B9C181!9BE918DC179EEDC1C$A9-7F7E%8C17$$8DC1!7899EB1C3!FE%8C91FC199C1 1C1F7FEBE7D1Q1B-!E%8C1R1CD7$ B9E7C1UF E7D1CD7$ B9E7E%8C1C1F1!97BBC1781C1F1 !97E1A7$EDFC1DB 9EC89C10C<1C107$$C1781079$7D7B0 9!EC181F7D17891!7891DC91C1 F1 !97BBC+1 F E7D1 CD7$ B9E7E%8C1 0C<1 C1 *C$$C1 -DB1 8DC1 ACDC1 CD7$1B9C1 *7DBE7DDCFZV711849E617615,E7F38E417[18D1BE81CB1B9D*79$ 1CD18D18B9C1781FED*F8CDC18D1 BE81 5CDB1 DC1 9C!7C1 !7891 FEDBDB1 %8C1 891 FC3! 9E$CDBBE7D1 DE$FC71 C1 F E7D1 CD7$ B9E7E%8C1!7899ECDB1:B9C1C7DE9C181F1E**8E7D18DC18ABDC1!AFC1C1BE$8FC91781 ED8E9C1 8DC1 E** 9CDEBE7D1 C1 B-!C1 !EB0 FEF1 81 DE6C81 81 BE81 E$!FDBBE7D1 U !EB0 FE8$1 SF7$E%8CV1H@2HA71C1BCDBBE6C1ED8BE7D10C<1FC19BC1C1F E7D1CD7$ B9E7E%8C1!91ED5CBE7D1 C1 FE%8EC1 ! 9EB7D F1 E81 C1 *C$$C1 BBCEDB1 CD7$ B9E7C1 7DB1 58%8F791 078 1F(71 1 C1 5789+1 88DC1 B8C1 D1 7D1 !81 7D*E9$C91CBBC1 B0 79EC1 D1 FC!1C1 08$EDC71 1 849E61 761 6>4561 AA3F5AE961 68B4F1 5A8EF61 CB1 67%8 C1 !7891 C3!FE%8C91 FC1 F7FEBE7D1 DFE7DDE9C1 C1 F1 $FECF)1 EDE1 %8C1 FC1 F7FEBE7D1 81 EBDC1 81 !CF6E1 U8BD C+1 !8F$7DE9C+1  9 A9FCZV71 1 849E617613655F5614F36167489EA5619C!7DB1891FC3EBCDC1C1CFF8FC1780C1E98FDBC1 79EEDE9C1C1F1$7CFFC17C8C1-DB1F1!97!9E B 1C1C1E** 9CDEC91CD1BE81CD7$ B9E7E%8C181C1 EBC1 69EAFC1 1 B 1 8 9 C1 !F81 9 C$$CDB1F'71 C1 C3! 9ECDC1 C1 9C**C1 C1 $7CFFC1 7C8C1 7DBCDDB1 C1 CFF8FC1 !97 DEB9EC1 CD7$ B9EFC1 0C<1 F1 789E1 C$AFC9ECDB1 9 EBC91 CBBC1 0-!7B01C1FE71

61>A6147A68A5611

D1 9C*F831 $CDB98CF1 !0-E7F7E%8C1 7AC96C1 0C<1 @(1 81 A(L1 C1 *C$$C71 379+1 8DC1 CD7$ B9E7C1 DC1 C1  6CF7!!C1 %8C1 0C<1 @1 81 )(L1 CDB9C1 CFFC71 5E1 F1 9 89EBBE7D1 C1 CFF8FC1 CD7$ B9EFC181B96C91C1B97$!C1D1F16EB 1! 9EB7D FC1CB1FC1!7EDB1C1 !9B1C1F1$FEC+1 7D1  6CF7!!C$CDB1 E$!FE%8C1 8B9C1 $ DE$C71 C1 $7E*EBE7D1 C1 FCD7$1B9C1 C8B7!E%8C1 7E6CDB1 9CD9C1 !AFC1 FC1 CFF8FC1 CD7$ B9EFC1 C1 E$!FDBC91 CB1 C1 !97FE* 9C91 D1 F1 6EB 1 ! 9EB7D FC714FFC2$:$C17EB117DBEB8C918D1CD6E97DDC$CDB1*679AFC181 6CF7!!C$CDB1C1F E7D711 C1 !0 D7$1DC1 6EDB1 81 !97$7867E91 FC1  6CF7!!C$CDB1 C1 FCD7$ B9E7C1 7DB1  !CDDB1 C1 *BC891 D BE%8C+1 !E D BE%8C+1CD6E97DDC$CDB83+1E$$8D7F7E%8C1CB1ED*F$$B7E9C1)71

1 1 ,67489E461

)E1

F1 1 B 1 $7DB9 1 %8C1 FCD7$1B9C1 C8B7!E%8C1 C1 *C$$C1 CD7$ B9E7E%8C1 E**19C1 C1 FCD7$1B9C1 C1 *C$$C1 D7D1 CD7$ B9E7E%8C1 $:$C1 E1 CF1 CB1 0EB7F7E%8C$CDB1 EDEC9DAFC+1 B78B181$7ED1CD1$E977!EC17!BE%8C1CD17F79BE7D1BD971F1CB1FC1E1C1D7$FEC1$7F 8FE9C1 *679EDB1 FC1  B0C$CDB1 C1 *9$CDB1 CD7$1B9C+1 FC891 896EC1 CD1 C0791 C1 F8B 981 CB1 FC891 !97FE* 9BE7D1 Q!9 E!7DBR1 81 9E%8C1 CD7$ B9E7C71 C1 FB 9BE7D1 $7F 8FE9C1  9EBC1 D1 FCD7$1B9C1 C8B7!E%8C1 C3EBCDB1 FC$CDB1 D1 FC1 F E7D1 CB7!E%8C1 $E1 C1 $DE19C1 $!FE*E C71 CF1FEC18!!7C918D17DBED88$1CDB9C1FCD7$1B9C1C8B7!E%8C1CB1FCD7$1B9C1CB7!E%8C17DB1FC1 D7$FEC1 $7F 8FE9C+1 781 FC**CB1 8D1 CD6E97DDC$CDB1 E** 9CDB1 U6EB 1 ! 9EB7D FCV+1 1 C9ECDB1 $579 C1CB1CBED C181*679EC911F1896EC1C1FCD7$1B9C1CB7!E%8C1F+1FH71

1

#7E41

0 9CDC1 C1 CFF8FC1 CD7$ B9E7E%8C1 CB1 *679E C1 !91 8DC1 89C3!9CE7D1 CD<-$C1 !97B 7F-BE%8C1 CB1 C1 *BC891 0 E7D1 %8E1 !C9$CBBCDB1 FD9C1 C1 CFF8FC1 CD7$ B9EFC1 81 F1 89*C1 81 ! 9EB7EDC71 4D1 EB8BE7D1 !0-E7F7E%8C+1 C831 $ BFF7!97B C1 $B9EECFFC1 U4462&1 CB1 4462))V1 C3!9E$ C1 D1 FCD7$1B9C1 81 7891 C1 91FC1 EDBC96ECDDCDB1 D1 F1 CB98BE7D1 C1 F1 $B9EC1 C3B92CFF8FE9C1 F791 C1 F1 C%8$BE7D1 C1 F !EB0 FE8$1 FD8FE9C71 4D1 !0C1 F8B FC+1 FC3!9CE7D1C1C1$ BFF7!97B C1CB19 !9E$ C710C<1FC1!BECDBC1CD7$ B9E7E%8C+14462&1CB1 4462))1 7DB1 C3!9E$ C1 C1 *;7D1 7DBED8C+1 81 F1 *7E1 D1 FCD7$1B9C1 C8B7!E%8C1 CB1 D1 FCD7$1B9C1 CB7!E%8C1 FF71 1 CB98BE7D1 F7FC1 C1 F1 $B9EC1 C3B92CFF8FE9C1 81 $ 7B0 FE8$1 ! 9EB7D F19 C1C1<7DC10 9CDC1*679AFC181FE$!FDBBE7D1C1CFF8FC1CD7$ B9E7E%8C1FC2 FA

71 C1 C9DE19C1 C3!9E$CDB1 !91 EFFC891 C1 !97B EDC1 0 E7D1 BCFFC1 %8C1 C1 EDB 9EDC+1 F1 F$EDEDC+1F1420 9EDC1CB1F1*EA97DCBEDC1C(2C)71

1

0A386F91945A=E4=EF61

D1 6EB97+1 FCD7$1B9C1 CB7!E%8C1  91BC1 C1 *;7D1 D79$FC$CDB1 FC6 C1 C1 D7$A9C831 *BC891C197EDC1U49.+1.9.+19.+169.+149.V1CB1C1-B7TEDC1U2)+12C+12@V1!9BEE!DB181F1 896EC1C1E$!FDB1CD1FC89189DB18DC168F9EBE7D1! E*E%8CC'2CE71

1

(945E9A8E41

F1 1 B 1 $7DB9 1 8DC1 !97FE* 9BE7D1 98C1 C1 CFF8FC1 CD7$ B9E7E%8C1 !91 FC1 AEE1 8DC1 BE6BE7D1C167EC1C1EDFEBE7D1>DB1CB1+18DC19 !9CE7D1C11DC1!972!7!B7BE%8C1UE81 C1F1*$EFFC1#3V1CB18DC189C3!9CE7D1C11DC1DBE2!7!B7BE%8C1UE81C1F1*$EFFC1#F'V1CH1$E1 FC$CDB1!91FC1AEE181B9C173-DB1H71

)H1

ED*F$$BE7D1097DE%8C1CB18DC1C1!9EDE!FC19B 9EBE%8C181BE81CD7$ B9E7E%8C71 4FFC1 CB1 7E C1 81 8DC1 89!978BE7D1 C1 !97BFDEDC+1 C1 $ BFF7!97B C1 $B9EECFFC1 CB1 C1 -B7TEDC1)+1CF2CA711!978BE7D1C1-B7TEDC1!972ED*F$$B7E9C1U)\+1C1CB12.]V1*679EC1F0 E7D1 C1 *9$CDB1 CD7$1B9C1 81 ! 9EB7EDC1 CB1 F1 FEA 9BE7D1 CD<-$C1 !97B 7F-BE%8C1 CD1 !C9$CBBCDB1 FE$!FDBBE7D71 462)1 UE3D3!4A5 2AE3B447B4BD45 6734AFD5 "V+1 @1 CB1 2451 UAB4A#5 $63D5 C4F%B4F3D5&37EB5'A5()67A**A#5BD#5A7A4A#V19C98BCDB1C1!7F-D8F E9C+1C1CFF8FC1G1CB1C1 $97!0C1 7DB1 F1 %8DBEB 1 CB1 9B 9EBE%8C1 C1 F E7D1 CD7$ B9E7C1&(2&)71 C1 A78FC1 8B79 8FBE7D1 !7EBE6C1 !C9$CBB9ECDB1 F1 !C9EBDC1 CB1 F8$8FBE7D1 C1 CFF8FC1 E$$8DEBE9C+1 C1-B7TEDC1CB1C10E$E7TEDC181CED1C1F E7D1&'71

ED*F$$BE7D1 CB1 FC$CDB1 FE C1 81 8DC1 89!978BE7D1 C1 !97BFDEDC1 1 694'1 CB169.']1 D1 FCD7$1B9C1 C8B7!E%8C1 CB1 D1 FCD7$1B9C1 CB7!E%8C71 4FFC1 !7899ECDB1 7DB9EA8C91 831 -$ D7990 C1 CB1 831 78FC891 !CF6ECDDC+1 D7D1 C8FC$CDB1 !91 FCDB9CBECD1 C1 F1 9 BE7D1 ED*F$$B7E9C1$E1 FC$CDB1!91FC1AEE181 FCD0C$CDB1C17DB9BE7D18B 9EDC1&E711

CDC$AFC1 C1 C1 D7$FEC1 8B72CDB9CBCD8C1 9 8FBCDB1 CD1 !9BEC1 8DC1  9 8FBE7D1 079$7DFC181CED1C1F E7D1CD7$ B9E7E%8C711

C1 CFF8FC1 CB1 FC1 $7F 8FC1 EDBC96CDDB1 D1 F1 9 BE7D1 ED*F$$B7E9C1 7AC96CDB1 CD1 7DCDB9BE7D1 FC6 C1D1FC1FE%8EC1! 9EB7D F1C1!BECDBC1CD7$ B9E7E%8C71C891B831CB1799 F 1 81F1 6 9EB 1C1F1$FEC7167891C9BED1EF1C9EB18D1!97$7BC891BE*1C1F197EDC1C1F E7D1&H711

1

'69?894=E6

1

197EDC+1FC1 6CF7!!C$CDB1CB1F1896EC1C1E$!FDB1CD7$ B9E7E%8C1CB1*679E C1!91 8DC1!978BE7D198C1SB971DC1U0E=F9619V710C<1FC1*C$$C1CD7$ B9E7E%8C+1FSB9E7F1CB1 !978EB1D11F76E9C+1F1!C81CB1FC1BE81E!C831$E1 FC$CDB1D1FCD7$1B9C1CB7!E%8C71D1 F76E9C+1781FED*F8CDC1C1F1.531CB1C1F13+1FC107FCB 97F1CB17D6C9BEB1CD1D97B1DCE7DC1!8E1CD1 SB97DC1 !91 F97$BC+1 F8E2$:$C1 B9D*79$ 1 CD1 SB9E7F71 D1 F1 !C81 CB1 FC1 BE81 E!C83+1 F97$BC1 !C9$CB1 FC$CDB1 F1 7D6C9E7D1 C1 FD97B1DCE7DC1 CD1 SB9E7F71 1 F791 %8CFFC1 CB1 D79$FC$CDB1 ACDBC1 D1 FCD7$1B9C+1 F97$BC1 CB1 C3!9E$ C1 D1 FCD7$1B9C1 CB7!E%8C71 CFFC2E1 BE$8FC1 F1 -DB01C1 C1 !97BFDEDC1 CD1 !9BE8FEC91 F1 694'1%8E1 CFFC2$:$C1 BE$8FC1 F1 !978BE7D1 97$BC71 F1 C3EBC1 7D1 8DC1 A78FC1 8B72BE6BE7D1 BE$8FDB1 F1 !97FE* 9BE7D1 C1 E$!FDB1 CB1 %8E1 C3!FE%8C1 F1 9CFBE6C1 EDC**EEB 1 C1 B9EBC$CDB1 079$7D831 6EDB1 81 ED0EAC91 F1 -DB01C1SB971DC1F71

1 1 ,67489E461

)F1

1 1 D1FC1BE81CD7$ B9E7E%8C1CB1!F81!9 E $CDB181DE6C81C1CFF8FC1B97$FC+1EF1C3EBC1 8DC1 78C3!9CE7D1 C1 FE7*79$C1 #1 81 9 C!BC891 81 F1 !97CB 97DC71 D1 FCD7$1B9C1 D79$F+1 F1 !97CB 97DC1ED8EB1FC3!9CE7D1C1F1)&1\'10-973-2C0-97 DC1%8E1$ BA7FEC1FSB9E7F1CD1 SB97DC71 D1 FCD7$1B9C1 C8B7!E%8C1 C1 !BECDBC1 CD7$ B9E7E%8C1 CB1 C1 *;7D1 CD79C1 !F81  $7DB9BE6C1 D1 FCD7$1B9C1 CB7!E%8C+1 1 F1 9 EBDC1 C1 CFF8FC1 CD7$ B9E7E%8C1 81 F1 !97CB 97DC1C$!:0C1F1-DB01C1C1F1)&1\'10-973-2C0-97 DC1CB1A78BEB181F8$8FBE7D1 SB971DC1*679EDB1F1!C9EBDC+11F197EDC1CB1F1!97FE* 9BE7D1C1F E7D1&F7111

1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1

1

1

1

1

#589A8E417615A19461EFE8AE961

1 896EC1 C1 CFF8FC1 CD7$ B9EFC1 D1 F1 6EB 1 ! 9EB7D FC1 CB1 FE C1 81 8DC1 ED!EB 1 81 -B1$C1 E$$8DEBE9C1 81 FE$EDC91 FC1 E$!FDB1 81 F1 89*C1 81 ! 9EB7EDC1)+1 &C2&&71 F1 CD1 9 8FBC1 8DC1 ED*F$$BE7D1 097DE%8C1 F7FC1 9C!7DAFC1 8DC1 !978BE7D1 98C1 C1 -B7TEDC+1 C1 *BC891 C1 97EDC1 CB1 C1 *BC891 !972DE7 DE%8C1 *679EDB1 C832$:$C1 FC1  6CF7!!C$CDB1 C1

1 0E=F961 91B1 3AE61 761 5,69?894=@E61 7A1 5,67489E46C1 1 !978BE7D1 7CB971DC17AC96C1D1F76E9C+1C1F1!C81CB181BE81E!C831$E1 FC$CDB181CED1C1 F1F E7D1CD7$ B9E7E%8C1CFFC2$:$C1%8E1C3!9E$C1F97$BC71

1 1

)C1

FCD7$ B9E7C1 CF7D1 8DC1 8B79 8FBE7D1 !7EBE6C1F(1 71 C9BED1 C1 C1 *BC891 CDCD9CDB1 8DC1 FB 9BE7D1C1FE$$8DEB 1CFF8FE9C1CB1C1FE$$8DEB 108$79FC1&@71F11 B 17AC96 18DC18$CDBBE7D1 81 D7$A9C1 C1 $97!0C1 BE6 +1 C1 F-$!07-BC1 21 CB1 C1 CFF8FC1 G1 D1 FC1 FE%8EC1 ! 9EB7D F1 7E C1818DC1E$ED8BE7D1!973FC1C1FBE6EB 1 C1CFF8FC1G1&@2&A1CB1C1F1!07-B7C1!91FC1 $97!0C1&'+1@(711E$ED8BE7D1C1!EB 1C1!07-B7C1C9EB11FE C181F1!9 CDC18DC1!97B EDC1 !970C1 C1 F0!B7F7AEDC+1 1 F1 !97B EDC1 4D71 )+1 D1 FC1 CFF8FC1 !EB0 FEFC1 CD7$ B9E7E%8C+1 !AFC1C1C1FEC91831$97!0C1BE6DB1F1!978BE7D1FC1CB1ED0EADB1F1!07-B7C1@)711

C1$97!0C1578CDB1CD178B9C18D19PFC1CDB9F1D1FC1 6CF7!!C$CDB1C1F E7D1!91F1 !978BE7D1C1*BC891!972DE7 DE%8C1U.9.+1DE7 DEDC+149.V1@'2@H1CB1C1E6C9C1-B7TEDC1@F71 C1CB1F)(1E$ED8CDB1FC1D7$A9C1C1F-$!07-BC121H120)1D1FC1! 9EB7EDC1@C+1FC129.\1ED0EAC1FC1 CFF8FC1 G1&@2&A1@&2@@+1 F@1 CB1 FC1 2.]1 BE$8FCDB1 F1 97EDC1 81 BE81 CD7$ B9E7E%8C1 CB1 FC1 CB1 FC1 2.]1 1 8$CDBCDB1 F0-!C9SB97 DEC1@A71 C1 F E7D1 !978ECDB1 CFFC2$:$C1 C1 -B7TEDC1 0E$E72 BB9BDBC1!7891FC1$97!0C1U)+146)+1245V1A(2A'71

1 !9 CDC1 8B72DBE79!1 CB1 DBE79!1 DBE2CD7$1B9C1 D1 FC1 FE%8EC1 ! 9EB7D F1 1 8 9 1 8DC1 79EEDC1 8B72E$$8DC1 81 FCD7$ B9E7C1 6C1 C1 $ DE$C1 $7F 8FE9C1 7$!BEAFCAE71

0A386F9176197E4E8E41

CD7$ B9E7C1 CB1 7DE 9 C1 7$$C1 8DC1 A5A7E61 =8EF61 3456H61 7DB1 FC3!9CE7D1 9 8FBC1C1FC**CB17$AED 1C1*BC891 D BE%8C1CB1CD6E97DDC$CDB83714FFC1CB1!97AAFC$CDB1781 F1  !CDDC1 C1 !F8EC891 1DC1 9 !7DDB1 81 8DC1 0 9 EB 1 $8FBE*B79ECFFC1 7DB9E9C$CDB1 81 C9BEDC1!B07F7EC1$7D7 DE%8C17[18D1C8F11DC1$8B 1CB19C!7DAFC1C1F1$FEC71

0A386F91=8EF61

DC1!9 E!7EBE7D1*$EFEFC181FCD7$ B9E7C1CB18!CB C1C!8E1C1D7$A9C8C1DD C71 C1 B8C1C1*$EFFC17DB17D*E9$ 1%8C1F1!9 6FCDC1C1FCD7$ B9E7C1 BEB1!F81 FC6 C10C<1FC1 !!9CDB C1 81 )C91 C9 1 C1 *C$$C1 BBCEDBC1AH1 CB1 C1 !9C86C1 CD79C1 !F81 7FEC1 7DB1 B 1 !!79B C1!91F B8C1C158$CFFC107$7<-7BC1CD7$ B9E7E%8C1!C9$CBBDB1C10E**9C91F1!9B1C1 *BC891 D BE%8C1D1F1896CD8C1C1F1$FEC181F)L1AF71C17DD C17DB1C!CDDB19 C$$CDB1 B 1$EC1CD178BC1AC1CD19E7D1C1AEE1CB1C1*BC8917D*7DDB1!786DB1*8C91FEDBC9!9 BBE7D1 C1 9 8FBB1 C1 B8C1 *$EFEFC1 U8D1 $C$A9C1 8DC1 *$EFFC1 78**9DB1 8DC1 $FEC1 EDEBC1 FC1 8B9C1 $C$A9C1 81 7D8FBC9+1 FC1 *BC891 C1 9E%8C1 C1 F1 $FEC1 !C86CDB1 C832$:$C1 67E91 8D1 9B19C1 *$EFEFZV71 ECDBE*EBE7D1 C1 1DC1 C1 !9 E!7EBE7D1 D1 FCD7$ B9E7C1 %8E1 CB1

1 1 ,67489E461

)&1

7DE 9 C17$$C18DC1$FEC1$8FBE DE%8C1CB1E**EEFC7117DB9EA8BE7D1C10%8C11DC1CB1*EAFC+1 C1D7$A9C8311DC1!C86CDB1:B9C1E$!FE%8 1CB1FC19E%8C1C1 6CF7!!C91F1$FEC1CB1786CDB1$7E*E 1 !91FCD6E97DDC$CDB1A&71C194#A*5#+B**3FB4F3D559C!7DB1891F1 FCBE7D1C11DC1DEB107EE1 891F1AC1C17DDEDC1!0-E7!B07F7E%8C1CB1FC194#A*5#A5FBF*3D59C!7DB1891FC1!9EDE!C1C1 F1 FEE7D1  D BE%8C1 %8E1  EDC1 FC1 *EB1 %8C1 C831 FF1FC1 C1 C831 1DC1 E** 9CDB1 7DB1 B9D$E1 CDC$AFC18D1EDE6E81811CCDDC1D7DB1!1!C9$E1ECDBE*EC91C11DC1C1!9 E!7EBE7D1A@71  C$$CDB+1 C831 %8E!C1 7DB1 9!!79B 1 FC1 9 8FBB1 8DC1 DF-C1 F7AFC1 81 B9D9E!B7$C1 7$!9DB1 FCD7$1B9C1 C8B7!E%8C1 81 FCD7$1B9C1 CB7!E%8C1 6C1 8DC1 7D79DC1 C1 @)L1CF+1 AA711 #790CC1 CB1 F71 $7DB9CDB1 %8C1 1 !F81 C1 F(((1 1DC1 7DB1 ED8EB1 781 9 !9E$ 1 D1 FCD7$1B9C1 CB7!E%8C1 7$!9BE6C$CDB1 81 FCD7$1B9C1 C8B7!E%8C1AA71 C1 1DC1 ED8EB1 7DB1 E$!FE%8 1 D1 F0 E7D1CFF8FE9C1CB1F1$B9EC1C3B9CFF8FE9C1BDE1%8C1FC11DC19 !9E$ 17DB1E$!FE%8 1D1FC1 -FC1CFF8FE9C71F1$7DB9CDB1 FC$CDB18DC1FB 9BE7D1C1F19 8FBE7D1C11DC13731E$!FE%8 1D1 F1 E** 9CDEBE7D1 CFF8FE9C71 1 $:$C1 %8E!C1 1 $7DB9 1 !F81 9 C$$CDB1 8DC1 7EBE7D1 CDB9C1 8D1 !7F-$79!0E$C1 81 1DC1 42E1 E$!FE%8 1 D1 C1 !0 D7$1DC1 C1 $ B0-FBE7D1 !9 CDC1 CB1 FCD7$ B9E7C1769ECDDC)((7111

C1 B8C17EBE7D181 D7$C1UAD3EA'F#A5C**3FB4F3D54#FA*V17DB19 C$$CDB1$E1 CD1 6ECDC1C1!7F-$79!0E$C1D8F 7BEE%8C17E 181FCD7$ B9E7C1)()2)(E71

0A386F916AE94668AFH1

C1698F9>A86F9167439EE6+17$$C1FC1#E!0 D7F21U#6V1CB1FC1!0BFBC+1%8E1 7DB1C1 CDB10E$E%8C1-DB1F1!97!9E B 1C1$E$C91FC1C**CB1C1079$7DC1DB89CFFC1CD1EDBC9* 9DB16C1 FC1 67EC1 C**CB9EC1 C1 C1 079$7DC1 7DB1 B 1 7E 1 81  6CF7!!C$CDB1 C1 FCD7$ B9E7C71 C1 $:$C1 F1 7E4HE6)(H1 +1 9C978!DB1 8DC1 *$EFFC1 C1 !7FF8DB1 9C5CB 1 !91 FBE6EB 1 ED8B9ECFFC1 1 B 1 ED9E$ED C71

,E5F6361 761 5,A5E68A8E41 D1 F1 896CD8C1 C1 $FEC1 SB97 D72 !CDDBC1 7DB1 FCD7$ B9E7C1 *EB1 !9BEC+1 1 B 1 !9BE8FE19C$CDB1 B8E C1 C1 6EDB1 C9DE19C1 DD C71 1 7D7$$BE7D1C16  B831CB1C1*98EB1*9E11 B 17E C1818DC19 8BE7D1EDE*EBE6C1819E%8C1C1  6CF7!!C91 8DC1 CD7$ B9E7C1 F791 %8C1 F1 7D7$$BE7D1 C1 098BC9EC1 CB1 C1 6EDC1 978C1 C$AFC1817DB9E9C1:B9C18D1*BC891C19E%8C1)(F71C1$ DE$C1 67%8 1C9EB1%88D19 E$C19E0C1CD1 9EC1 !7899EB1 8$CDBC91 FC1 B831 SB971DC1 E98FDB1 CB1 EDE1 *679EC91 FC1 $FEC1 SB97 D72 !CDDBC1)(C71

)@1

0A386F91E=8EF61

BE7D1 C1 *BC891 CD6E97DDC$CDB831 !7899EB1 :B9C1 $ E C1 !91 8DC1 $78FBE7D1 !E D BE%8C1 C1 FC3!9CE7D1 C1 C9BED1 1DC1 D7B$$CDB1 !91 8DC1 FC1 AEE1 8DC1 $7E*EBE7D1 81 !97*EF1C1$ B0-FBE7D1C1!97$7BC891C1C11DC1)(&71C1$ DE$C11 B 17AC96 1D1FC3!9CE7D1 8D1 1DC1 E$!FE%8 1 D1 F1 B 97X7 D1C+1 FC1 5.2)1 UBC97E7CDE1 .B792)V+1 7DB1 FC1 !97$7BC891CB1  $ B0-F 1 D1 FC1 F E7D1 CD7$ B9E7E%8C1 C1 %8E1 A78BEB1 81 8DC1 0-!C9!978BE7D1 F7FC1 SB971DC1F711

27489E4616813A3691

#ECD1 %8C1 FCD7$ B9E7C1 7EB17DE 9 C1 7$$C1 8DC1 $FEC1 A DEDC+1 EF1 BCD181 C1  C91 C1E$EFEB8C1CDB9C1FC17$!79BC$CDB1C1CFF8FC1CD7$ B9E7E%8C1CB1C1CFF8FC1D 9C8C71C1 CFF8FC1CD7$ B9E7E%8C1!9 CDBCDB1CD1C**CB1F1!EB 1C1E $EDBE7D1CD1E$!FDBDB181DE6C81 C1 EBC1 CB7!E%8C1 69E 1 UDFE7DDE9C1 CB1 81 EBDC1 81 !CF6EV+1 ED6E7D1 CD1 ED*EFB9DB1 FC!C1 782! 9EB7D F1CB1F1!97E1C179DC+1C1!97FE* 9BE7D1CB1C1D 7DE7 D1C1)(@7111

C!CDDB+1FE8C1C1F1$FEC1DCB1!1*BFC1CB1CB1!7891CBBC19E7D1%8C1FCD7$ B9E7C1!C8B1 :B9C17DE 9 C17$$C18DC1Q1$FEC1$ BBBE%8C1A DEDC1R71

CD7$ B9E7C1DC1C$AFC1!1:B9C17E C1818D19E%8C1981C1DC91CD1 D 9F1$E1CB1 7E C1 81 8D1 9E%8C1 981 C1 DC91 769ECD1 81 CFF8FC1 FE9C1 781 C1 B-!C1 CD7$ B9E7XC1 6C1 8D1 9E%8C19CFBE*169EDB1CDB9C1)+E1CB1'1)(A2))(71D1CD6E97D1C(L1C1DC91769ECD1896CDDB1D18D1 7DBC3BC1CD7$ B9E7C+1FC1BE81B8$79F1CB15CDB181BE81CD7$ B9E7E%8C1781D^B1C1CF8E2E+1 8 9DB1F1!7EAEFEB 18DC1B9D*79$BE7D1$FEDC1)))2))'71

C1 D7$FEC1  D BE%8C1 CB1 097$77$E%8C1 7$$8DC1 6C1 FC1 DC91 C1 FCD7$1B9C1 781 FC1 DC91 769ECD1 7DB1 B 1 9!!79B C1 D1 FCD7$ B9C1 C8B7!E%8C1 CB1 FCD7$1B9C1 CB7!E%8C1 C1$FC1CD7$ B9E7E%8C1BCF1%8C1FBE6BE7D1C1!97B727D71DC1U2TEB+129V+1!C9BC1C11DC1 8!9CC891 C1 B8$C891 U624+1 !FEV+1 DC8!F7XEC1 81 097$77$C1 )&+1 !C9BC1 0 B 97<-7BEC1 !7891 !F8EC891F7E1C1097$77$C1A+1))1CB1''1))E171C1$:$C+1C1$71FC1$89ED1CD7$ B9E7C17DB1 B 19 1CD1BE6DB1F7D71DC1T21781CD1EDBE6DB1FC11DC18!!9CC891C1B8$C8916241))H2))F71 79%8C1 FC1 789E1 !9 CDBCDB1 FC1 C831 $8BBE7D+1 CFFC1  6CF7!!CDB1 8D1 DC91 CD7$ B9E7XC1 9!EC$CDB1 $79BCF1))C1 CB1 F79%8EF1 C3EBC1 8DC1  F BE7D1 C1 6241 D1 F8B 98+1 CFFC1  6CF7!!CDB1 8D1 DC91 CD7$ B9EF1 ED6E*1))&71 C!CDDB+1 81 FED6C9C1 C1 C1 %8C1 F7D1 7AC96C1 D1 FC1 DC91 C1 F76E9C+1 1 8DC1 FB 9BE7D1 C1 F8BC91 C1 1DC1 3/1 7E C1 81 8DC1 9 !9CE7D1 C1 1DC1 81 -FC1 CFF8FE9C11 B 1 9EBC1D1FC1CD7$ B9E7$C1769ECD1AA71CE1819C1F1!9 CDC1C1$ DE$C1 C17DB9PFC181!7BCDBECF17D71DC1C1F1$FEC1C1%8E161D1FC1CD1 B8C19 CDBC+18BEFEDB1

1 1 ,67489E461

)A1

C1 !!970C1 DF-C1 F7AFC+1 CD1 *6C891 C1 FACDC1 C1 9E%8C1 C1   D 9CCDC1 9ED7$BC8C1))@71

!89A8=E6189A6F8EF61

1 !9EC1 CD1 09C1 C1 $FC1 !79BC8C1 CD7$ B9E7C1 CB1 $8FBEEE!FEDE9C+1 E FC$CDB1 9 FE C1 81 CED1 C1 CDB9C1 C1 9 * 9CDC1))A71 4FFC1 7EB1 BCDE91 7$!BC1 81  E91 C1 97CC+1 C1 F1 !9 CDC1C1*BC891ED*C9BEFEB 17E +1819B19C1$8FBE*7F1C1F E7D1CB1C1F0 B 97 D EB 1 C1F1$FEC71

9AE866817E3A51

F1CB1079$7DF1CB19C!7C1891FC1AF7C1C1F1*7DBE7D1769ECDDC71F1CB1!97!7 1CD1C0791C1 B78B1  E91 C1 97CC1 CB1 DCB1 %8C1 -$!B7$BE%8C71 6F8EC891 FC1 B0 9!C8BE%8C1 BCFFC1 %8C1 F1 !EF8FC1 SB972!97CBBE6C+1 FC1 !97CBBE*1 CB1 FC1 DF78C1 C1 F1 9D01 7DB1 E!7DEAFC71 C891 C**EEB 1 BDB1 E$EFE9C+1 1 FC1 07E31 C1 *7DC1 891 FC1 7NB1 CB1 FC1 C**CB1 C7DE9C1)'(71 D1 CBBC1 7!BE%8C+1 F1 7DB9C!BE7D1 79FC1 7$AED C1 CB1 81 !97!7C91 CD1 !9C$E19C1 EDBCDBE7D1)')71 C**EEB 1 9CFBE6C1C1B9EBC$CDB1079$7D831CB1CD1!9BEC1FE C181F19 EBDC181F1!97CB 97DC17AC96 C1D1 FC1CFF8FC1CD7$ B9E7E%8C1%8E1E$ED8C1FC**EEB 1C1!97CBBE*1C1-DB01C1CB181F1!978BE7D1 97$BC1%8E11ED8EB18DC1!978BE7D1F7FC18B7D7$C1SB971DC711

EDC**EEB 1 C1 F1 !97CB 97DC1 891 F1 !97FE* 9BE7D1 C1 CFF8FC1 CD7$ B9E7E%8C1 !C8B1 C3!FE%8C91 !91 C1 $7E*EBE7D1 C1 FC3!9CE7D1 C1 C1 9 C!BC891 81 F1 89*C1 C1 CFF8FC1 CD7$ B9E7E%8C1)71 C1 9 C!BC891 81 F1 !97CB 97DC1 !71C1 C831 E7*79$C+1 FC1 9 C!BC891 81 F1 !97CB 97DC11U62V1-DB18DC1BE6EB 1ED0EAEB9EC1CB1FC19 C!BC89181F1!97CB 97DC1#1U62#V1-DB1 8DC1BE6EB 1BE$8FB9EC1)''17162#1CB1782C3!9E$ 1D1FC1F E7D1CD7$ B9E7E%8C1EDE1%8C1D1 FCD7$1B9C1 C8B7!E%8C1 C1 !BECDBC1 CD7$ B9E7E%8C1)'E1 CD1 9E7D1 8DC1 0-!C9$ B0-FBE7D1 C1 F1 9 E7D1 !97$7B9EC1 C1 7D1 1DC1)'H71 C1 !F8+1 FED6FEBE7D1 C1 62#1 !9767%8C1 FE$$79BFEBE7D1 C1 CFF8FC1 B97$FC1 CD7$ B9EFC1)'F71 D1   %8EFEA9C1 C1 F1 AFDC1 CDB9C1 FC1 E7*79$C1 1 CB1 #1 81 9 C!BC89181F1!97CB 97DC11 FC$CDB1 B 1$7DB9 1D1FC1DC971DC18$CDBBE7D1819BE7162 W62#11 B 1$7DB9 C1D1FC19ED7$C1CD7$ B9EF1)'C1CB1CB17E 1818D1$86E1!97D7BE)'&71C1 $:$C+18DC18$CDBBE7D1819BE7162W62#11 B 1$7DB9 C1D1FC1DC9181CED+1CD17EBE7D1 6C18DC1E$ED8BE7D1C1F0 E7D1CFF8FE9C1CB18DC18$CDBBE7D1C1F1!97FE* 9BE7D1CFF8FE9C1)'@71C1 $:$C1  %8EFEA9C11 B 1$7DB9 1D1FC1CFF8FC181CED1D79$FC1!79BDB1F1$8BBE7D1#)1)'A71

C1 D<7F1 CB1 8D1 B9EBC$CDB1 079$7DF1 DBE27D7B97!C1 7DD81 !7891 67E91 C1 !97!9E B 1 DBE2!97FE* 9BE6C+1 DBE297$BC1 CB1 E$$8D72$78FB9EC1 FD5 %F4735)E(1 C!CDDB1 C1 !97!9E B 1 D97 DE%8C1!C86CDB1FC19CD9C1E**EEFC$CDB1B7F 9AFC1!91FC1!BECDBC711

'(1

C1ED0EAEBC891C1F97$BC1UDB97<7FC+1FCB97<7FC+1C3C$BDCV17DB181F1*97DBE19C1CDB9C1 FC1B9EBC$CDB1079$7DF1CB1FC1B9EBC$CDB1DBE2B8$79F71F17DB18BEFE 1D1FC1B9EBC$CDB1586DB1C1 DC91 81 CED1 079$7D7 !CDDB1 0C<1 FC1 *C$$C1 $ D7!8 C71 1 F1 7DB1 786C9B1 8DC1 D786CFFC1 67EC1 B0 9!C8BE%8C1 D1 FCD7$ B9E7C1 C!8E1 8DC1 E<EDC1 DD C1 )E)2)E'1 CD1 9E7D1 C1 F1 89C3!9CE7D1 C1 F97$BC1 D1 FC1 F E7D1 CD7$ B9E7C1 CB1 D1 FCD7$1B9C1 C8B7!E%8C1 C1 !BECDBC1 CD7$ B9E7E%8C1F+1 )EE+1 9C!7DAFC1 8DC1 !978BE7D1 F7FC1 SB971DC1 CB1 C1 F1 9 EBDC1831!97CBBE*1CB18317DEBC1C1F19D371F17DB1D D$7ED18BEFE 16C1!9E$7DEC1 CD1 9E7D1 C1 FC891 C**CB1 891 F1  !F BE7D1 7C8C1 CB1 C1 F1 D CEB 1 C1 FC1 7EC91 81 8D1 B9EBC$CDB1 AF7%8DB1F1*7DBE7D1769ECDDC10C<1FC1*C$$C1D7D1$ D7!8 C1)EH1UCB181E9C1F1!7!8FBE7D1C1 *C$$C1CD7$ B9E7E%8CV1E$!7DB17D18DC1$ D7!8C10E$E%8C711

189C3!9CE7D1C1F97$BC1D1FC1CFF8FC1CD7$ B9E7E%8C1CB1CD1!9BEC1FE C1818DC1 BE$8FBE7D1C1-B7TEDC1!972ED*F$$B7E9C17$$C1FC1CB1F)1)EE711

9AE866813E9F9=E3A51

11 B8CFFC$CDB+1 C8FC1 8DC1 0E989EC1 C3BCDE6C1 7$!9AFC1 81 8DC1 0E989EC1 9ED7F7E%8C1 Q1(1R1 9C!7DB1 891 FC3 91C1 C1 B78BC1 FC1 F E7D1 CD7$ B9E7C1 CD1 9DB1 !7891 7A5CBE*1 F1 7DC96BE7D1 C1 F1 * 7DEB +1 !C9$CB1 C1 7DB9PFC91 F1 -$!B7$B7F7EC1 78F789C8C1)EF2)EC1 CB1 C1 !9 6CDE91 FC1 9 EE6C1'A+1 )E&71 D1 FC1 1 C1 FCD7$ B9E7C1 !97*7DC1 6C1 BBCEDBC1 9CBFC+1 F1 EB1 8DC1 0E989EC1 F789C1 D CEBDB1 D1 F1 $579EB 1 C1 1 F1 9 FEBE7D1 8DC1 EF 7B7$EC1 C1 !97BCBE7D1B9DEB7E9C1CB17E C1818DC1$79AEEB 1!97!9C71

1C3 91C1C1F1F E7D19CBFC1E$!FE%8C18DC1!97BCB7$EC18A2B7BFC1781B7BFC1CF7D1FC1DE6C81 81!PFC1ED* 9EC891C1F1F E7D1!919!!79B181!0EDBC91DF71CBBC1C3 91C1C$!79BC1CD1$7D7AF71FC1 8F2C21 6EDF1 !7B 9EC891 CB1 FC1 FE$CDB28B 9729 1 F79%8EF1 7DB1 BBCEDB71 DC1 C7DC1 F7FEBE7D1E$7XECDDC1CB19  %8 C16C1F1!E1C1C1!97BCB7$EC71C1F7FEBE7D1EF 727FE%8C1 97EBC17E6CDB1:B9C1BBCDBE6C$CDB19C0C90 C1CD1!C927! 9B7E9C191FE$C9EC1*EB1 *8B1D1!F81 C1 F(1 L1 C1 1 U7DD C1 !C97DDCFFC1 D7D1 !8AFE CV71 4FFC1 1 !C86CDB1 :B9C1 B9EB C1 !91 !!CDECB7$EC+19 CBE7D18D E*79$C181C8$+19 CBE7D1EF FC17819 CBE7D1EF 72CFC1CF7D1F1 F7FEBE7D71C18B89C1ECBE6C1U7F729CBFCV1CB16EDFC17DB1 F C1891FC1!FD1DB7$E%8C1CB1 !97B  C1F8DC1C1F8B9C1!91FEDBC9!7EBE7D18DC1 !E!F77!FBEC71DC1EF 7B7$EC1C1!97BCBE7D1CB1 -B $BE%8C71 C1 !9 8BE7D1 !C9$CBBCDB1 C1 *EFEBC91 F1 CBE7D1 8DC1 6CDB8CFFC1 *EB8FC1 9CB72 6EDFC71C189CB19C17DB18E6E1891FC891B95CB1 EBF1*ED1C189C91C1FACDC1BB9BE7D1 781 ED*EFB9BE7D1!91FC1D78FC1CD7$ B9E7E%8C71DC1BBCEDBC189 B 9FC1C3B9ED1%8C1CB1B9EB C1!918DC1 89 B 97F-C1 C1 Q1 7$!9CE7D1R1 !97B  C1 !91 8DC1 7DC1 78AFC1 ,71 DC1 BBCEDBC1 89 B 9FC1 EDB9ED1%8C1 CB1 B9EB C1 !91 8DC1 9 CBE7D1 8E6EC1 8DC1 9 E$!FDBBE7D1 89 B 9726 EFC1 781 !91 8DC1

1 1 ,67489E461

')1

D !09CB7$EC1CD11C1CB98BE7D1819CED1C7DE9C181F89 B 9720-97D !097C1097DE%8C1)E@71C1 B9EBC$CDB1 C1 F E7D1 DDC3ECFFC1 CB1 FC1 !F81 7DC96BC891 !7EAFC71 F1 7EC1 C1 *;7D1 69EAFC+1 T-BCB7$EC1 769ECDDC+1 769ECB7$EC+1 F!EDCB7$EC1 CB1 DDC3CB7$EC71 DC1 0-B 9CB7$EC1 D7D1 7DC96B9EC1DCB19 FE C1%8C10C<1C1$FC1 FCBE7DD C1C1!F81C1H(1D1CD11BBCEDBC1 DDC3ECFFC1AEFB 9FC1CB1ACDC1C1 E91C197CC711!9 CDC18DC1CD7$ B9E7C16 EFC1CB1 B9EB C1!91-BCB7$EC1!9BECFFC1)EA71278BC1FC1F E7D1! 9EB7D FC18!C9*EECFFC17DB1 B98EBC71

EF 7B7$EC1 C1 !97BCBE7D1 CB1 *C9$ C1 81 @1$C1 57891)H(1 CD1 1 C1 DDC91 6C1 7!E*EBE7D1 !91 FEF 7B7$EC1 $7DB9DB1 FACDC1 C1 *EB8FC1 781 C1 7FFCBE7D1)H)71 D1 FC1 1 7DB9E9C+1 CFFC1 CB1 *C9$ C181'1$7E7117$!FEBE7D1!9EDE!FC1C1CBBC1EDBC96CDBE7D1CB1F1896CD8C18DC1DC8976CEC1 ! 9E!0 9E%8C1%8C1F7D17AC96C1D1)CL1C11)H'714FFC1CB1FE C181B98$BE$C178181F1CBE7D1C1 9$C831 DC96C831 E81 C1 !FC381 0-!7B9E%8C1 ED* 9EC891 CB1 7AC96C1 !F81 *9 %8C$$CDB1 CD1 1 DB7$7C1 7F72DFC+1 0-B 9CB7$EC1 B7BFC1 CB1 F79%8EF1 -1 1 !F81 C1 H1 F E7D1 CD7$ B9E7C1 !97*7DC1)H'71 C1 9 8FBB1 C1 CBBC1 0E989EC1 7DB1 BE*EDB1 D1 AHL1 C1 1 6C1 8D1 B831 C1 9 EE6C1!97*7DC1 6F8 181'L+1D19 EE6C1ECBE6C1)H'71EDBC96CDBE7D1CB1$CD C1!91F!977!EC1 D1 C831 BEC91 C1 71 1 8!EE7D1 8DC1 BBCEDBC1 897F7E%8C1 EDB9ED1%8C1 7DBEB8C1 CD79C+1 !7891 D78+18DC1FE$EBC181CBBC167EC1A7971

1 1 D1 8D1 7DBC3BC1 ED*C9BEFEB +1 FC1 B9EBC$CDB1 0E989EF1 $ FE79C1 F1 *C9BEFEB 1 DB89CFFC1 81 7DEBE7D1BBCD9C18D1 FE18**E$$CDB1F7D1U8D1D11CD1$7-CDDCV1)HE71

#E8A3617E3A561D15A19439A8E411

1 1 0C<1 FC1 !BECDB1 ED*C9BEFC+1 F1 * 7DBE7D1 ED1 6EB971 CB1 F1 BC0DE%8C1 C1 9 * 9CDC71 4FFC1 !C8B1 :B9C1!97!7 C16DB1F10E989EC1781F17$!F BC91E'71

''1

3AE617615A1945E69A8E41

!89614H7A81

$EE8E41

C1.79$C1 BE6C1C1F_3-1DC1U.V17811CBE6C13-CD15!CEC1U5V17DB1C1*79$C1  9E6 C1C1F73-1DC18119DC19 BE6EB 10E$E%8C714FFC1EDF8CDB1FC19E831FEA9C1C1F73-1DC181 !97!9C$CDB1!9FC911EDF8DB11FDE7D18!C973-C1'`2+1FC19EF10-973-FC13`1CB1FC1$7D73-C1<7BC1 `1EDE1%8C11C1*79$C1BE6C1C1F73-1DC1D7D19EFE9C17$$C1FC1!C973-C1_0-971DC13''1 CB1 1 FC1 DEB97!C973-C1 371 C1 9E831 FEA9C1 7DB1 C1 C!1C1 0E$E%8C1 UB7$C1 781 $7F 8FCV1 7DB18D1781!F8EC891 FCB97D17DB1D7D1!!9E 7110%8C1B7$C1CB1*79$ 18D1D7-817$!7 1C1 !97B7D1CB1C1DC8B97D+1CB1 FCB97D196EBDB18918DC179AEBFC18B789181D7-817[1EF17DB1!!9E 1 C83181C837179%8EF1DC17DB1!1!!9E +1FC891BCDDC1DB89CFFC1CB1EDBC9E916C1FC1 FCB97D1 C1 $7F 8FC1 781 B7$C1 67EED1 !7891 9C*79$C91 C1 FEE7D1 0E$E%8C1 76FCDBC71 CBBC1 !97!9E B 1 7D*19C1 8DC1 9DC1 EDBAEFEB 1 831 B7$C1 7DB1 FC1 FCB97D1 7DB1 D7D1 !!9E 1 781 831 $7F 8FC1 %8EF1*79$CDB1)HH7111

C19E831FEA9C1!C86CDB1:B9C1*79$ 1!91F1!C9BC1781FC1ED18D1 FCB97D1"1 /1 1C21a1/`a111  BE7D173-BE7D1

/1a1C21 11111111/`21111  BE7D1C19 8BE7D1

 BB19EFE9C1CB1B9DEB7E9C1CB1!9CD1*ED17EB1!91C!BBE7D18D1 FCB97D17EB1!91FC1B9D*C9B1C1 F FCB97D1FEA9C18918DC18B9C1$7F 8FC715E1FEDBAEFEB 1819EF1FEA9C1CB1$7 9 C+1F1!97AAEFEB 1%8EF1 C!BC1 8D1 C7D1 FCB97D1 CB1 *79BC71 D1 C1 +1 FC1 9EF1 FEA9C1 DC1 9C!9 CDBC1 %88DC1 B!C1 B9DEB7E9C1D18DC19 BE7D173-79 8BE7D715E1 FEDBAEFEB 1819EF1FEA9C1CB19DC+1F FCB97D1 FEA9C1 CB1 9!EC$CDB1 B9D* 9 1 891 8DC1 8B9C1 $7F 8FC1 CB1 !C8B1 !9BEE!C91 81 C1 !0 D7$1DC1 73-BE7D1 CD1 0EDC1 )HF71 C!CDDB+1 E1 F1 D786CFFC1 C!1C1 9EFE9C1 CB1 BAFC+1 CFFC1 !78991 7$!F BC9119 BE7D173-79 8BE7D1CD1C19  D 9DB1UED18D1 FCB97DV1781CD173-DB1U!C9BC1 8D1C83E1$C1 FCB97DV711

C831 9E831 FEA9C1 !C86CDB1 EDBC9E91 CB1 *79$C91 8DC1 $7F 8FC1 73-DBC1 D7D1 9EFE9C71 67891 C3C$!FC+1 C831 DE7D1 8!C973-C1 '`21 !C86CDB1 *79$C91 81 !C973-C1 0-971DC1 3''1 CB1 FEDBC9BE7D1 8D1 DE7D1 8!C973-C1 '`21 1 6C1 81 $7D73-C1 <7BC1 `1 !C8B1 *79$C91 81 !C973-DEB9EBC12171

1 1 !89614H7A81

'E1

1 !978BE7D1 C1 .1 CB1 F1 7D %8CDC1 81 $ BA7FE$C1  97AEC1 CB1 1 7!19C1 CD1 7DBED81 D1 B78BC1 FC1 CFF8FC1 C89-7BC71 C1 .1 7DB1 FE$ED C1 CD1 !C9$DCDC1 !91 !F8EC891 -B1$C1 DBE73-DB71C8917DCDB9BE7D1EDB9CFF8FE9C1CB1EDE1*EDC$CDB19 8F C71

613AE61761947F38E4176149619A38EA617615,4H=@611

C1$ DE$C1C1!978BE7D1C1.17DB19C!9 CDB 10E=F961&C1

,AE41F694H761"

DI15

1

DE7D18!C973-C1CB1*79$ 1!91FEBE7D18D1 FCB97D181F1$7F 8FC173-1DC1"1 '11a11C211111111111111111'`2

1

C19EF1CB19CFBE6C$CDB1BAFC1CB1!C8B1E**8C9181EBDC1C17D1EBC1C1*79$BE7D1)HC71F1CB1!C81 B73E%8C1 CD1 F8E2$:$C1$E1 !C8B1 9 E91 6C1 FC1 !C973-C1 0-971DC13''1781 FC1 $7D73-C1 <7BC1 `11CB17DDC91DEDC181C1!8EDB173-DB1BCF1%8C1FC19EF10-973-FC13`1CB1FC1!C973-DEB9EBC1 2+19C!CBE6C$CDB

1

)H&71

B8B9C1-B1$C1CD<-$BE%8C1CFF8FE9C1!C86CDB1A78BE9181F1*79$BE7D1DE7D18!C973-C1"1

• ,B52B-DA57A*6F7B43F7A5EF4323D#7FBA55

B8B9C26EDB1 E31 !789CDB1C1 F1 !978BE7D1 DE7D1 8!C973-C11 9 8FBC1 81$ BA7FE$C1  97AEC1 CB1 !976ECDB1 C1 F1 0^DC1 9C!E9B7E9C1 $EB707D9EFC )H@71 89DB1 F1 !07!079-FBE7D1 73-BE6C+1 8D1 9ECDB1 C1 !97B7D1 CB1 BAFE1 81 CED1 C1 F1 $C$A9DC1 $EB707D9EFC+1 7DBEB8DB1 8DC1 789C1  DC9EC1!7891F1-DB01C1C1F26711!978BE7D1DE7D18!C973-C1CB17E C181C1!97C81 $ BA7FE%8C1!918DC19 8BE7D1$7D76FCDBC1C1F73-1DC181!9BE91C1 FCB97D11FEA 9 1!91F10^DC1 9C!E9B7E9C71CBBC1!978BE7D1CB17DBED8C+18AE%8EBE9C1CB19C!9 CDBC1(7'L1C1F73-1DC17D7$$ 1 !91F10EDC19C!E9B7E9C1)HA71

• ,A5!A5B4B!4FA5#A*5!43273EA*56./01

C1 -B7097$C1 !HF(1 7DB1 C1 0 $7!97B EDC1 *79$DB1 C1 7$!FC3C1 CD<-$BE%8C1 %8E1 73-CDB1 C1 8AB9B1 U3V1 !91 FEDBC9$ EE9C1 1 81 E73-1DC1)HH1 CD1 !9 CDC1 8D1 CDB1 9 8BC891 U3'V+1  D 9FC$CDB1FC163+1CF7D1F19 BE7D18E6DBC1"1

1 1 1 1 31a1'1a13'1111111111131a11a13'1

79%8C1 FC1 E73-1DC1 8AEB1 8DC1 9 8BE7D1 $7D76FCDBC1 1 !F8BPB1 %8C1 :B9C1 FE 1 81 8AB9B+1 CBBC1 9 BE7D17D8EB181F1*79$BE7D1DE7D18!C973-C1"1

1 1 1 1 U3VU3V1a1'1111111111111111U3V1U3aV1a111'`1211

• ,A*5&C1153)!#B*A*52&34555

C1 /1 7DBEB8CDB1 8DC1 *$EFFC1 CD<-$C1 $579EBE9C$CDB1 E$!FE%8 C1 D1 F1  *CDC1 DBEAB 9ECDDC1 CB1 F1 EDFEBE7D1 CFF8FE9C71 C1 7DB1 C1 !97B EDC1 $8FBE$ 9E%8C1

'H1

B9D$C$A9DE9C1 %8E1 E1CDB1 81 CED1 C1 F1 $C$A9DC1 !F$E%8C1 CB1 C1 C9BEDC1 $C$A9DC1 EDB9CFF8FE9C1)F(714FFC1BF-CDB1F19 8BE7D1$7D76FCDBC181E73-C1CD1DE7D18!C973-C181!9BE91 81631)F)"1 1

631a1'1

'

11111111116

a

1a13

a

1a1'1

'•21

• ,B5)BD42FDA53)!#B*A524355

1 3DB0EDC1 73-C1 CB1 8DC1 C1 C831 *79$C1 CD<-$BE%8C1 C1 F1 3DB0EDC1 73-79 8BC1 U/V;1 F8B9C1 BDB1 F1 1 3DB0EDC1  0-97 DC1 U/3V1)F'71 C1 C831 CD<-$C1 EDBC96ECDDCDB1 D1 F1  9BE7D1 C1 AC1 !89E%8C1 CD1 BF-DB1 F73-BE7D1 C1 F0-!73DB0EDC1 CD1 3DB0EDC1 CB1 C1 F1 3DB0EDC1CD1EC189E%8C7111/1CDB9^DC1F19 8BE7D1C1F73-1DC1CD1DE7D18!C973-C1CB1F1/31 CDB9^DC1F19 8BE7D1C1a1CD137111

D1 C1 7DEBE7D1 D79$FC+1 F1 /31 CB1 F9C$CDB1 $579EBE9C1 CB1 FC1 $ BA7FE$C1 C1 AC1 !89E%8C1 9C!9 CDBC1 7D1 8DC1 789C1 D FECAFC1 DE7D1 8!C973-C71 C!CDDB+1 D1 C9BEDC1 7DEBE7D1 !B07F7E%8C1 7$$C1 D1 FC1 -D97$C1 E0 $EC29C!C9*8E7D+1 F1 /31 C1 7D6C9BEB1 CD1 /1C1%8E1CB181F79EEDC18DC1!978BE7D1E$!79BDBC1DE7D18!C973-C1)HH71

61694H7617,794=@61'

D

"

D

1

C1 !C973-C1 0-971DC1 !C8B1 !976CDE91 E9CBC$CDB1 C1 F1 9 8BE7D1 C1 F73-1DC1 $7F 8FE9C1781FC**CB1C1E6C9C1CD<-$C17$$C1F1F87C173-C1"1

1 1 1 1 '1a1'13a11a11'1C211111111113''11

81:B9C1*79$ 181!9BE91DE7D18!C973-C1!91C18!C973-C1E$8BC1U5V1"1 1 1 1 1 ''`21a1'3a1111111113''1a1'1

C1 !C973-C1 0-971DC1 CB1 9CFBE6C$CDB1 BAFC71 691 EFFC891 EF1 1 F1 !EB 1 C1 B96C9C91 FC1 $C$A9DC1AE7F7E%8C1)FE1C1%8E1C3!FE%8C1%8EF1!C8B1C1B9786C9181EBDC1C17D1FEC81C1!978BE7D71 51 B73EEB 1 9C!7C1 891 1 !EB 1 81 C1 9 8E9C1 CD1 9EF1 0-973-FC1 3`108BC$CDB1 9 BE*1 7D1 B73E%8C1CD1!9 CDC1E7D1$ BFFE%8C1BCF1%8C1FC1E7D1*C99C831.C'a11CB18E69C18'a75

619A7E3A51794H561"'

I

1

1 !9EDE!FC1 67EC1 C1 !978BE7D1 81 9EF1 0-973-FC1 E$!FE%8C1 FC1 BE7D1 $ BFFE%8C1 D7B$$CDB1*C91CB18E69C1)FH2)FF171F1EB1C1F19 BE7D1C1 AD43D1"11

3''a1.C'a1111111111.CEaa1'13`1

C!CDDB+1 1 !978BE7D1 !C8B1 FC$CDB1 C1 *E9C1 ED !CD$$CDB1 C1 BE7D1 $ BFFE%8C1 !91 EDBC9BE7D1 CDB9C1 FC1 !C973-C1 0-971DC1 CB1 FDE7D1 8!C973-C71 1 F1 EB1 C1 1 F1 9 BE7D1 B6A7' AF**1"111 1 1 3''a1'`211111111111'1a1'13`1

81!91FEDBC9BE7D1CDB9C1FDE7D18!C973-C1CB1FC1$7D73-C1<7BC1"1

1 '`21a1`1111111111121a13a11111111113111111111111113`1a1'2111111111111111E21a13a1

81 CD79C1 !91 FEDBC9$ EE9C1 C1 F1 $- F7!C973-C1 F7FE C1 D1 FC1 9D8FC1 <897!0EFC1 C1 !7F-D8F E9C1DC8B97!0EFC1CB1C1$7D7-BC1"1

1 1 !89614H7A81

'F1

F21a3''1a13a1111111113F1a13'1 1!8E111 131a1'`21111111111111113`1a1F21a1'111

C19EF10-973-FC1CB1F1*79$C19 BE6C1C1F73-1DC1F1!F81EDBAFC17D1F1!F819 BE6C715189 C1 C1 6EC1 CB1 C3B9:$C$CDB1 *EAFC1)FC2)F&71 C1 9EF1 E**8C1 !C81 CB1 9 EB1 %8E$CDB1 891 FC1 FEC81 C1 1 !978BE7D1 1 CD1 990DB18D1 FCB97D1 781 8D1 B7$C1 0-971DC1 8D1 8AB9B1 79DE%8C1 31 781 CD1 EBE7DDDB1891FC178AFC1FEE7D71

6144H7617,AJ4861"

I

1

C1 $7D73-C1 <7BC1CB1 -DB0 BE 1 !0-E7F7E%8C$CDB1 81 !9BE91 C1 F1 29EDEDC1 !91 F1 2 -DB0C1CB1578C18D19PFC1$5C891D1FC1B7D8168FE9C711*79BC17DCDB9BE7D1FC1$7D73-C1<7BC1 C6ECDB1C!CDDB1 F B19C1!7891FC1CFF8FC+1D7B$$CDB1CD19 EDB16C18D19EF18!C973-C1 !7891*79$C91FC1!C973-DEB9EBC121%8E1CB18D1!8EDB173-DB71C1C9DEC91!C8B1C7DE9C$CDB11C1  7$!7C91CD18B9C173-DB17$$C1FC1'`1781FC1`71

613AE61761784HEE3A8E4176149619A38EA617615,4H=@61

C1$ DE$C1C1 B73E*EBE7D1C1.17DB19C!9 CDB 10E=F961&71

D1 DBE73-DB1 C1  *EDEB1 7$$C1 B78BC1 8ABDC1 %8E+1 F79%8CFFC1 CB1 !9 CDBC1 81 *EAFC1 7DCDB9BE7D17$!9BE6C$CDB181CFFC18D18AB9B173-AFC+19CB9C1781!9 6ECDB1EDE*EBE6C$CDB1 F73-BE7D1 C1 C1 8AB9B1)HH71 D1 EBED8C1 FC1 DBE73-DB1 CD<-$BE%8C1 CB1 FC1 DBE73-DB1 D7D1 CD<-$BE%8C71

!8@616JA8EF6

1

!8@61416JA8EF6

1 25EEA8E417615,AE41F694H761 C18!C973-C1E$8BC1 C1EB$EDC11CB141 1 C1*F67D7XC1 1 C197B D7XC1 1 8AE%8ED7DC1U7CD<-$C1B)(V1 25EEA8E417F1694H7617,794=@61 1BFC1 C1EB$EDC11CB141 C1F8BB0E7D1!C973-C1CB1FC1F8BB0E7D19 8BC1 C1F8BB0E7D1U953V1 6C973-9 73EDC1CB1B0E79 73EDC19 8BC1 1B0E79 73EDC1 DBC9DFEBE7D16E1FC19 C!BC89181B9D*C99EDC1 1 5B7TC1!91F1*C99EBEDC1 1 1

61F694H7617EF8A61K!"$L1

C151BF-CDB1F1E$8BBE7D1C1C831DE7D18!C973-C1CD1!C973-C10-971DC"11 '1'`21a1'3a11111 113''1a1'1 CBBC1 9 BE7D1 C**CB8C1 !7DBD $CDB1 $E1 CB1  F 9 C1 8D1 *BC891 C1 )(1(((1 CD1 !9 CDC1 C1 51)HH71D1EBED8C1B97E179BC1C151D1F1CFF8FC1C89-7BC"1 !"$1

'C1

• 15)1818E69C1CB181<ED1U82=D5V1!9EDE!FC$CDB1F7FE C1D1FC1-B77F1

• 15'181$DD1C1U4D5V1EB8 C181DE6C81C1F1$B9EC1$EB707D9EFC714FFC1578C18D1 9PFC1$5C891D1F1 B73E*EBE7D1C1.1!8E%8C1D1C17DEBE7D1!0-E7F7E%8C+1A(L11 CDB9C1CFFC17DB1!978EBC1!91F10^DC19C!E9B7E9C1$EB707D9EFC1

• 15E1818E69C1CB181<ED1U425V1!9 CDBC1CD1$579EB 1D1FC1$EFEC81C3B92CFF8FE9C1)F@2)FA71 C151578CDB18D19PFC1$5C891D1F FE$EDBE7D1C1FDE7D18!C973-C1!978EB1!91FC1$ BA7FE$C1  97AEC+1 F1 631 73-C1 CB1 FC1 -B7097$C1 !HF(71 C!CDDB+1 FC**CB1 DBE73-DB1 C1 51 CB1 7DEBE7DD 1 !91 F1 !7EAEFEB 1 !7891 F1 CFF8FC1  FE$EDC91 C**EC$CDB1 FC1 !C973-C1 0-971DC+1 F8E2 $:$C1B73E%8C+1!978EB1!91F151)C(71BE6EB 1C151CB17D1B9EA8BE9C1C1CD<-$C109 C1  FE$EDC91FC1!C973-C10-971DC+18167E91F1BFC1CB1F1F8BB0E7D1!C973-C71

A13A8A5A61

1 BFC1 CB1 8DC1 !C973-C1 81 D7-81 01$C1 7DB1 F1 -DB01C1 CB1 !97!79BE7DDCFFC1 81 F1 7DCDB9BE7D1 C1 !C973-C1 0-971DC71 4FFC1 BF-C1 E9CBC$CDB1 F1  7$!7EBE7D1 81 !C973-C1 0-971DC1CD1C81CB1CD1E73-1DC1"11 '13''111111111113'1a1'1 4FFC1 CB1 !9EDE!FC$CDB1 F7FE C1 D1 FC1 ! 973-7$C1 CB1 DCB1 !+1781 B911 !C8+1 !9 CDBC1 D1 FC1 $EB707D9EC711

61=5F8A8E41694H7A61KC(HL1681561=5F8A8E41KC!'L1

C1 F8BB0E7D1 !C973-C BF-CDB1 F1  7$!7EBE7D1 81 !C973-C1 0-971DC1 CD1 78!FDB119 8BE7D1CD13'16C1F73-BE7D181F8BB0E7D19 8EB1U953V1CD1AE8F*89C1C1F8BB0E7D1 U9559V"11 1 1 '19531a13''11111111195591a1'3'1

C1 9631 7DB1 $579EBE9C$CDB1 F7FE C1 D1 FC1 -B7!F$C71 1 !F81 9DC1 !9BEC1 81 !C973-C1 0-971DC1!978EB181DE6C81C1$EB7079EC178181-B7!F$C1CB1 FE$ED 1!91FC19631!F8BPB1%8C1 !91 F1 BFC1)HH71 DC1 !CBEBC1 !97!79BE7D1 CB1 D D$7ED1 !9 CDBC1 D1 F1 $B9EC1 $EB707D9EFC1 $E1 FC1$EB7079EC1 BDB1  !78968C1 C1CD<-$C1 D CE9C1 81 F1 -DB01C1 81 953+1C1 C9DEC91 7EB1:B9C1E$!79B 181-B7!F$C71

C1 F8BB0E7D1 U2b2F8B$-F22-BCED-F2F-EDCV1 CB1 -DB0 BE 1 !91 F_BE7D1 7D 8BE6C1 C1 F1 b2 F8B$-F-BCEDC1-DB0 BC1!8E1C1F19531-DB0 BC)C)7167891$EDBCDE918D19BE719531W195591 FC6 +1 F1*79$C173- C181F8BB0E7D1U9559V1CB19 8EBC1CD19531!91F1F8BB0E7D19 8BC1U9V71

1 1 !89614H7A81

'&1

61694HE974HE61K(9HL16815A18E4974HE61K 9HL1

C1 !C973E9 73EDC1 *79$CDB1 8DC1 *$EFFC1 C1 !C973-C1 1 81 978!C$CDB1 B0E7F1 !AFC1 C1 9 8E9C1 FC1 !C973-C1 0-971DC1CB1 8B9C1 !C973-C )C'2)CE71 4FFC1 !71CDB1 8D1 9 E81 -B EDC1 81 FC891C3B9 $EB 12BC9$EDFC1%8E17DBEB8C1FC1EBC1!9E$EBE*173-BE7D1!91FC1!C973-C10-971DC1"1

6932531a13''11111111116932531a13'1

1693173- C19 EB16C18DC18B9C1$7F 8FC1C16932531!7891*79$C918D1!7DB1E28F*EC1"1 6932531a16932531111111111693252526931a13'1

C1 E$19C1 E8F*EC1 CB1 9  D 9 1 CD1 6931 9 8EBC1 CD1 73-DB1 8DC1 $7F 8FC1 7DBCDDB1 C831 978!C$CDB1B0E7F15CDB+1F1B0E79 73EDC1"1

693252526931a12932U53V'111111111116932531a129325'1

C1 C831 978!C$CDB1 B0E7F1 C1 F1 231 *79$CDB1 8D1 !7DB1 E28F*EC1 %8E1CB1 9 8EB1 !91 F1B0E79 73EDC1 9 8BC1CD18BEFEDB1FC16317$$C17DDC891 FCB97D1"1

29325'1a1631a13a1111111116a1a12932U53V'1

C1 6931 7DB1 !9EDE!FC$CDB1 F7FE C1 D1 FC1 -B7!F$C1 CB1 FC1 $EB707D9EC71 C891 BE6EB 1 BF-BE%8C1CB1!F81*EAFC1%8C1CFFC1C1F1BFC1781C1F8BB0E7D1!C973-C $E1CFFC1!71CDB1 8DC1 *79BC1 **EDEB 1 6C1 FC1 !C973-C1 0-971DC71 4FFC1 !7899ECDB1 :B9C1 EDE1 !F81 C**EC1 !7891 FE$EDC91C1DE6C831*EAFC1C13''1)C'71

61AF89618@61

1 6EB$EDC1 41 UFE!7!0-FCV1 CB1 F1 6EB$EDC1 1 U0-97!0EFCV1 FE$EDCDB1 FC1 9E831 0-973-FC71 8AE%8ED7DC1 U72CD<-$C1 B)(V1 CB1 E$EFE9C1 81 8DC1 6EB$EDC1 CB1 578C1 8D1 9PFC1 EDE*EBE*1 D1 F1 !978BE7D1  DC9EC1 81 DE6C81 C1 F1 0^DC1 9C!E9B7E9C1 $EB707D9EFC1 CB1 8D1 9PFC1 DBE73-DB1 C1 !97BCBE7D1C1CFF8FC17DB9C1FC1C**CB1 F B19C1C19E831FEA9C71 1 1 1 1 1 1 1 1 1 1 E843479E61 #$('14H7A61

"

D I15 1

'

D

"

D

1

_'

D

"1

C!'1

C!!C1

C1

M1C!1

!"$1 F5:!"$1 2!"$1

!"$1

3A8E614H7A61

_A8A5A61

C(H1

0E=F961&1B1(947F38E416815EEA8E4176149619A38EA615,4H=@61

'@1 1

616681>E43EEF6176149619A38EA617615,4H=@61

C1 .1 !C86CDB1 EDBC9E91 CDB9C1 CFFC1 $E1 FC$CDB1 6C1 B781 FC1 B-!C1 C1 7$!7DB1 CFF8FE9C1 7$$C1 F+1 FC1 FE!EC+1 FC1 F8EC1 781 FC1 !97B EDC71 C891 C**CB1  !CDCDB1 C1 FC891 9 BE6EB 1!97!9C+1C1FC891**EDEB 1!9 * 9CDBECFFC16C18D18AB9B+1C1FC891%8DBEB 1CB1C1FC891!EB 1 C1E**8E7D71C1B9C173-DB1CB1 *EDE1!918DC18$8FBE7D1EDB9CFF8FE9C1C3CE6C1C1. )CH71F1 !C8B1:B9C1N1818D1C311C1!978BE7D1C1.1CBW781818D1 *8B1C1-B1$C1DBE73-DB71C1B9C1 73-DB1CB18D1!0 D7$1DC1!C9$DCDB1FE 181$ BA7FE$C1 97AEC711

#38E41F91,#$1

C1B9C173-DB1CB19C!7DAFC1C1F1*79$BE7D1C1)(F1F E7D1891F1C10%8C1CFF8FC1 !9157891!7BCDBECFFC$CDB1$8B1DC1)CF711$EB707D9EF1CB1!9BE8FE19C$CDB1C3!7 181B9C1 73-DB181*EB1C1F1!978BE7D1F7FC1C1.1!91F10^DC19C!E9B7E9C1)CC71C1B9C173-DB1CB1 E$!FE%8 1D1FC1!97C81C16ECEFFEC$CDB+1D18D19D1D7$A9C1C1!B07F7EC1  D 9BE6C1 CB1!C86CDB1!9BEE!C9181F1B9D*79$BE7D1CB181F1!979CE7D1B8$79FC7

1

#38E41F915615EE761

BE7D1 C1 .1 891 FC1 FE!EC1 799C!7D1 81 F1 !C973-BE7D1 FE!EE%8C71 4FFC1 7DC9DC!9EDE!FC$CDB1 FC1 EC1 91 !7F-EDB89 1 %8E1 7DB1 C1 7DBEB8DB1 $5C891 C1 $C$A9DC1 -B7!F$E%8C1 CB1 $EB707D9EFC71 4FFC1 1 !7891 7D %8CDC1 F1 B9D*79$BE7D1 C1 9E831FE!EE%8C1CD1F 0-C1%8E1C832$:$C1ED8ECDB1C1$8BBE7D1C1F1CB1FED8BE7D1C1 F!7!B7C1!91!C9$ AEFEBE7D1C1$C$A9DC1$EB707D9EFC1)CE71

#38E41F91561948E61

73-BE7D1C1!97B EDC1CDB9EDC1C1$7E*EBE7D17D*79$BE7DDCFFC+1C1*9$CDBBE7D1 781 C1 FEE7D1 CDB9C1 !97B EDC1 8C!BEAFC1 C1 $7E*EC91 FC891 BE6EB 1 D7B$$CDB1 E1 CFFC1 7DB1 C1 !97!9E B 1CD<-$BE%8C71

=F5A8E417F18A>45E613655F5AE961

81 *EB1 C1 FC891 !EB 1 81 $7E*EC91 C1 D7$A9C8C1 !97B EDC+1 FC1 .1 9 8FCDB1 C9BEDC1 BE6EB 1CD<-$BE%8C1CB1578CDB18D19PFC1D11F1B9D$EE7D181EDF1EDB9CFF8FE9C717B$$CDB+1 FC1 !C973-C1 0-971DC1 CB1 E$!FE%8 1 D1 F1 9 8FBE7D1 81 -FC1 CFF8FE9C71 4D1C**CB+1C1 !97B EDC1 B-97EDC2!07!0BC1U626V17DB1FC1CD<-$C1FC1!F81CDEAFC181F73-BE7D1ED8EBC1!91FC1! 973-C1 0-971DC71 DC1 *EAFC1 7DCDB9BE7D1 C1 !C973-C1 0-971DC1 ED8EB1 8DC1 EDBE6BE7D1 ! E*E%8C1 C16241!91*79$BE7D18D1!7DB1E8F*EBC181DE6C81C17D1EBC1CD<-$BE%8C1)C&711CBBC1EDBE6BE7D1 CDCD9C18D1 91FC$CDB1C1FBE6BE7D1G21-DB1!78917D %8CDC1F$!FE*EBE7D18D1$CC1

1 1 !89614H7A81

'A1

C1 896EC1 CFF8FE9C1 CB1 C1 !97FE* 9BE7D71 C1 !C973-C1 0-971DC1 EB1 FC$CDB1 891 FC1 46G1 U7F43AD'C4F%B4A#51734AFD5FDB*A*V1!91FC1AEE1C1F167EC14G1U()47BAB7'AB4A#5FDB*AV1!7891 BE6C91 C9BED1 *BC891 C1 B9D9E!BE7D1 CB1 $!FE*EC91 8D1 EDF1 C1 896EC1 CFF8FE9C1)C@71 1 8DC1 7DCDB9BE7D1 !F81 FC6 C+1 FC1 !C973-C1 0-971DC1 !C8B1 BE6C91 8B9C1 46G+1 FC1 56G1 U*47A**' B4F%B4A#56734AFD58FDB*AV1%8E1*679ECDB1F!7!B7C)CA71

1CDEAEFEB 1C1!97B EDC181B9C173-DB1DCB1!18DE*79$C71C1C**CB17!!7 1!C86CDB1 :B9C17AC96 1CD1*7DBE7D181B-!C1C1.1CB1C1FC8917DCDB9BE7D71D1B9C173-DB1$E*1ED8EB1F1 $79B1CFF8FE9C1CD1!9767%8DB1C1F E7D1$8FBE!FC1891F+1FC1!97B EDC1CB1FC1FE!EC711FED6C9C+1 8DC1 8$CDBBE7D1 !F81 $7 9 C1 C1 F1 7DCDB9BE7D1 CD1 !C973-C1 0-971DC1 !C8B1 $!FE*EC91 8D1 $CC1 C1 896EC1 CFF8FE9C1 CB1 C1 !97FE* 9BE7D1 CD1 $78FDB1 ! E*E%8C$CDB1 FBE6EB 1 C1 %8CF%8C1 !97B EDC10-!C9CDEAFC71C1$ DE$C1CB1E$!FE%8 1D1F7D7CD1C1)&(711

!89614H7A8168167489E461

6F8EC891 B8C17DB1$7DB9 18DC18$CDBBE7D181B9C173-DB1D1FC1 98$1CB1FC1FE%8EC1 ! 9EB7D F1C1*C$$C1CD7$ B9E7E%8C1)&)2)&E71

F11 B 1$7DB9 1D18DC1 B8C1$CD C1!91D7B9C1 %8E!C18DC18$CDBBE7D181B9C173-DB1 D1 FC1 CFF8FC1 !EB0 FEFC1 E8C1 CD7$ B9E7$C1 769ECD+1 C7DE9C1 81 8DC1 8$CDBBE7D1 C1 !978BE7D1 C1 *79$C1 9 BE6C1 C1 F73-1DC1 CB1 81 8D1  *8B1 C1  B73E*EBE7D1H71 CE1 !C8B1 :B9C1 CD1 !9BEC1C3!FE%8 1!91F BB1ED*F$$B7E9C1F7F11097DE%8C+17DD81!78918$CDBC91FC1B9C173-DB1)&H71 C1 $:$C1 B96EF1 1 !91 EFFC891 $E1 CD1 6ECDC1 8DC1 7EBE7D1 CDB9C1 F8$CDBBE7D1 81 B9C1 73-DB1 CB1 F8$CDBBE7D1 C1 F1 !97FE* 9BE7D1 C1 CFF8FC1 CD7$ B9E7E%8C1 !91 FC1 AEE1 C1 FBE6BE7D1C1F167EC14G1H71C1$:$C1$ DE$C11 B 1$E1CD1 6ECDC1D1FC1CFF8FC1D 9C8C1 )&(

71EDE+1FC1CFF8FC1CD7$ B9E7E%8C1C17$!79BCDB16E2826E181B9C173-DB17$$C1C1CFF8FC1 B8$79FC1 6C1 8D1 B9C1 C1 AC1 FC6 1 FC1 9CDDB1 CDEAFC1 81 C1 *EAFC1 69EBE7D1 C1 !C973-C1 0-971DCH71

1C1 9PFC1 81 B9C1 73-DB1 D1 F1 !B07 DEC1 C1 FCD7$ B9E7C1 1 B 1 7D*E9$ 1 FD5 %F%35 891 C1 $71FC1 $89ED1 CD7$ B9E7C1 5 B9EB 1 !91 8D1 DBE273-DB+1 F1 2 B-F2-B EDC+1 %8E1 !C9$CB1 D7D1 C8FC$CDB1 F1 9 8BE7D1 C1 E$!FDB1 CD7$ B9E7E%8C1 $E1 FC$CDB1 F1 E$ED8BE7D1 C1 !0 D7$1DC1ED*F$$B7E9C1F7831H+1)&F71