Two Panels, Eaoh With Multiple Boundaries

Na espectroscopia vibracional na região do infravermelho, foi identificado os principais modos vibracionais dos derivados fenantrolínicos que indicam a formação destes ligantes, tendo como exemplo, o estiramento carbonílico (C=O) para a phendiona e os estiramentos indicativos do anel imidazólico e dos grupos substituintes ciano e nitro para os compostos L-CN e L-NO2. Além disso, a partir dos espectros de IV dos complexos

e ligantes, foi possível determinar o modo de coordenação dos derivados fenantrolínicos e da INH, sendo via N,N’ e N,O’ respectivamente.

As bandas metal-ligante foram observadas pelos espectros Raman, podendo ser também avaliado por esta técnica, a modificação da simetria dos complexos, com a substituição dos cloretos pelas INH, de modo que as bandas da isoniazida demonstrarem inativas no Raman neste ambiente químico.

A espectroscopia eletrônica na região do ultravioleta e visível, indicou a coordenação dos ligantes a partir das transições intraligantes na região de 200 a 400 nm e bandas d-d nos espectros eletrônicos dos complexos. Os complexos [Cu(L)Cl2]

apresentaram as transições d-d nas regiões de 767 nm (CuPhend), 741 nm (CuLCN) e 732 (CuLNO2) e para os compostos [Cu(L)(INH)2]Cl2 em 760 nm (CuPdI), 721 nm

(CuCNI) e 719 nm (CuNO2I), demostrando a seguinte relação de desdobramento do

campo ligante Cl- < INH < Phendiona < L-CN < L-NO2 respectivamente.

Adicionalmente, a partir da técnica de fluorescência, foi possível verificar a emissão dos ligantes phendiona, L-CN e L-NO2, em 557, 488 e 564 nm, respectivamente.

Além disso, observou-se que os complexos com a phendiona não apresentaram mais emissão e para os compostos com os derivados L-CN e L-NO2 verificou-se uma inibição

da fluorescência destes compostos em relação ao ligante livre, devido a coordenação do Cu2+.

Através das voltametrias cíclicas dos complexos, observou-se os potencias redox para os pares Cu2+/1+ nos voltamogramas dos complexos [Cu(L)Cl2], porém, com a

substituição dos cloretos pela INH, foi possível observar os pares redox Cu2+/1+ e Cu1+/0. A partir dos resultados eletroquímicos também foi observado o alto caráter π receptor do ligante L-NO2, devido os potencias do metal nos complexos com este derivado estarem

em regiões mais positivas, comparativamente aos demais. Além disso, pelos voltamogramas dos complexos foi avaliado que todos os compostos apresentaram

potencias dentro da faixa redox do meio biológico, possibilitando assim a formação do Cu+ no meio celular.

Assim, os resultados obtidos a partir das técnicas espectroscópicas e eletroquímicas utilizadas para a caracterização dos compostos sintetizados neste trabalho indicaram uma boa correlação com as características esperadas para as estruturas propostas, indicando, portanto, a obtenção dos compostos de interesse.

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