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Note on estimates of the burden of disease in countries

Annex Tables 4 and 5 present the first country-specific estimates of the causes of the burden of disease and attributable risk, in terms of both deaths and DALYs, for the WHO European Region.

Annex Table 7 presents burden of disease estimates in DALYs in children aged 0–14 years. These estimates were produced in 2004, specifically for this report, by the Global Burden of Disease project of the WHO Global Programme on Evidence for Health Policy.

The estimates of the burden of disease elaborate on previous results of the 2000 Global Burden of Disease study (1) as published in the world health reports for 2003 and 2004 (2,3), and use the most recent additional information available to WHO in 2004.

The estimates of attributable risk elaborate on the comparative risk assessment analyses carried out for The world health report 2002 (4), but with updated country data on the burden from and exposure to around four of the risk factors. Some changes were made in methods and results, in general small ones, as compared to those of the 2002 report and published by Ezzati et al. (5).

These prior estimates should be interpreted as the best estimates of WHO, rather than the official estimates of Member States. They have been computed using standard categories and methods to ensure cross-national comparability, and may not be the same as official national estimates produced using different but potentially equally rigorous methods. Documentation and summary tables on the Global Burden of Disease study (6) are available, along with software tools and a manual providing guidelines for conducting a national burden of disease study (7).

References

1. Mathers C et al. Global burden of disease in 2002: data sources, methods and results. Geneva, World Health Organization, 2004 (http://www3.who.int/whosis/menu.cfm?path=evidence,bu rden,burden_gbd2000docs,burden_gbd2000docs_DP54&language=english, accessed 27 April 2005).

2. The world health report 2003 – Shaping the future. Geneva, World Health Organization, 2003 (http://www.who.int/whr/2003/en, accessed 25 May 2005).

3. The world health report 2004 – Changing history. Geneva, World Health Organization, 2004 (http://www.who.int/whr/2004/en, accessed 27 April 2005).

4. The world health report 2002 – Reducing risks, promoting healthy life. Geneva, World Health Organization, 2002 (http://www.who.int/whr/2002/en/, accessed 27 April 2005).

5. Ezzati M et al. Comparative quantification of health risks: global and regional burden of disease attributable to selected major risk factors. Geneva, World Health Organization, 2004.

6. The Global Burden of Disease project: results for 2002 and earlier years, methods,

documentation and publications. Manuals, resources and software for carrying out national burden of disease studies [web site]. Geneva, World Health Organization, 2005 (http://www.

who.int/evidence/bod, accessed 25 May 2005).

7. Mathers CD et al., eds. National burden of disease studies. A practical guide. Edition 2.0.

Geneva, World Health Organization, 2001 (http://www3.who.int/whosis/menu.cfm?path=evi dence,burden,burden_manual&language=english, accessed 25 May 2005).

Table 1. Population of the WHO European Region, 1990 to 2015 (projected)

Bosnia and Herzegovina Bulgaria

Croatia Cyprus Czech Republic Denmark

Republic of Moldova Romania

Russian Federation San Marino

Serbia and Montenegro Slovakia TFYR Macedoniac Turkey Turkmenistan Ukraine United Kingdom Uzbekistan

Total population (millions) 1990 2003 2015

Member State Average annual

population growth (%) 1990–2003 2003–2015

–0.3 2002 2015 43.2

Population under age 15 (% of total) 2003 2015

27.3

Population aged 65 and above 2003 2015

Total fertility

rate,

a Includes population of Kosovo until 2001.

b Data are for 1990 to 2001.

c The former Yugoslav Republic of Macedonia.

Sources: World development indicators 2005. Washington, DC, World Bank, 2005 (http://www.worldbank.org/data/wdi2005/; accessed 25 May 2005), and Human development report 2004. Cultural liberty in today’s diverse world. New York, United Nations Development Programme (http://hdr.undp.org/reports/global/2004/; accessed 25 May 2005).

Treatment success (%), 2002 Table 2. Basic public health indicators in the WHO European Region

Health expenditure, immunization and ill health

Member State Total health

expenditure, 2002

% of GDP

Per head (international

dollar rate) 6.1

Bosnia and Herzegovina Bulgaria

Croatia Cyprus Czech Republic Denmark

Republic of Moldova Romania

Russian Federation San Marino

Serbia and Montenegro Slovakia TFYR Macedoniac Turkey Turkmenistan Ukraine United Kingdom Uzbekistan

General government health expenditure, 2002

% of total expenditure

on health

% of total government expenditure

One-year-olds immunized (%), 2003

With DTP3

Against measles detected (%), 2003

c The former Yugoslav Republic of Macedonia.

Note. WHO computed the figures to ensure comparability; they are not necessarily the official statistics of Member States, which may use alternative rigorous methods.

Sources: The world health report 2005 – Make every mother and child count. Geneva, World Health Organization, 2005 (http://www.who.int/whr/2005/en, accessed 25 May 2005) and World health statistics 2005. Geneva, World Health Organization, 2005 (http://www3.who.int/statistics/, accessed 30 May 2005).

Life expectancy and mortality

Life expectancy at birth (years), 2003 Males Females

69

Adult mortality rate (per 1000 population aged 15–60 years), 2003

Males Females

167

Under-5 mortality rate (per 1000 live births) Under 5

years, 2003

Before 28 days, 2000

21

Maternal mortality rate (per 100 000 live births) WHO estimate,

2000

Reported, 1995–2003

Coverage of registration of deaths (%), 2003 or latest available year

94 Stunting

in children under 5 weight

(%),

Average annual growth of GDP (%)

Share of income or consumption (%)

Inequality measures GDP

Bosnia and Herzegovina Bulgaria

Croatia Cyprus Czech Republic Denmark

Republic of Moldova Romania

Russian Federation San Marino

Serbia and Montenegro Slovakia TFYR Macedoniaa Turkey Turkmenistan Ukraine United Kingdom Uzbekistan Member State

1980–1990 1990–2003 Poorest 10%

Poorest 20%

Richest 20%

Richest 10%

Ratio of income or consumption share of richest 10% to

poorest 10%

Gini Note. WHO computed the figures to ensure comparability; they are not necessarily the official statistics of Member States, which may use alternative rigorous methods.

Sources: World development indicators 2005. Washington, DC, World Bank, 2005 (http://www.worldbank.org/data/wdi2005/; accessed 2 May 2005) and Human development report 2004. Cultural liberty in today’s diverse world. New York, United Nations Development Programme (http://hdr.undp.org/reports/global/2004/; accessed 2 May 2005).

Table 3. Level and distribution of income in the WHO European Region

a The former Yugoslav Republic of Macedonia.

ALBANIAANDORRAARMENIAAUSTRIA

Table 4. Deaths and DALYs attributable to the 10 leading causes in the WHO European Region, 2002

Mortality DALYs

Member State

Causes Total

deaths

Cerebrovascular disease Ischaemic heart disease Lower respiratory infections Trachea, bronchus and lung cancer Stomach cancer

Liver cancer Perinatal conditions Hypertensive heart disease Nephritis and nephrosis

Chronic obstructive pulmonary disease All causes

1.

All causes 1.

Unipolar depressive disorders Ischaemic heart disease Cerebrovascular disease Perinatal conditions Lower respiratory infections Osteoarthritis

Falls

Iodine deficiency Hearing loss, adult onset Trachea, bronchus and lung cancer

502 753

Ischaemic heart disease Cerebrovascular disease Alzheimer’s and other dementias Trachea, bronchus and lung cancer Chronic obstructive pulmonary disease Colon and rectum cancer

Diabetes mellitus

Lower respiratory infections Breast cancer

Road-traffic accidents

Unipolar depressive disorders Alcohol-use disorders

Alzheimer’s and other dementias Ischaemic heart disease Cerebrovascular disease Hearing loss, adult onset

Chronic obstructive pulmonary disease Road-traffic accidents

Trachea, bronchus and lung cancer Diabetes mellitus

All causes 1.

All causes 1.

All causes 1.

All causes 1.

Ischaemic heart disease Cerebrovascular disease Diabetes mellitus

Trachea, bronchus and lung cancer Chronic obstructive pulmonary disease Inflammatory heart diseases

Hypertensive heart disease Breast cancer

Stomach cancer Cirrhosis of the liver

Ischaemic heart disease Unipolar depressive disorders Cerebrovascular disease Perinatal conditions Diabetes mellitus Hearing loss, adult onset Congenital anomalies Vision disorders, age-related Trachea, bronchus and lung cancer Chronic obstructive pulmonary disease 26 148

516 208 65 285 All causes

1.

All causes 1.

Ischaemic heart disease Cerebrovascular disease

Trachea, bronchus and lung cancer Colon and rectum cancer

Chronic obstructive pulmonary disease Cirrhosis of the liver

Breast cancer Self-inflicted injuries Diabetes mellitus Hypertensive heart disease

Unipolar depressive disorders Ischaemic heart disease Cerebrovascular disease Alcohol-use disorders Hearing loss, adult onset Alzheimer’s and other dementias Chronic obstructive pulmonary disease Trachea, bronchus and lung cancer Self-inflicted injuries

Cirrhosis of the liver 70 450

969 681 95 118

Source: data from Mathers C et al. Global burden of disease in 2002: data sources, methods and results. Geneva, World Health Organization, 2004 (http://www3.

who.int/whosis/menu.cfm?path=evidence,burden,burden_gbd2000docs,burden_gbd2000docs_DP54&language=english, accessed 25 May 2005).

AZERBAIJANBELARUSBELGIUMBOSNIA AND HERZEGOVINA

Table 4 contd

Mortality DALYs

Member State

Causes Total

deaths

Ischaemic heart disease Lower respiratory infections Unipolar depressive disorders Perinatal conditions Cerebrovascular disease Diarrhoeal diseases Tuberculosis

Hearing loss, adult onset Anaemia

Diabetes mellitus All causes

1.

All causes 1. 180 052 156 395 99 044

Ischaemic heart disease Cerebrovascular disease

Chronic obstructive pulmonary disease Poisonings

Self-inflicted injuries

Trachea, bronchus and lung cancer Stomach cancer

Colon and rectum cancer HIV/AIDS

Drownings

Ischaemic heart disease Cerebrovascular disease Unipolar depressive disorders Self-inflicted injuries Poisonings

Alcohol-use disorders

Chronic obstructive pulmonary disease HIV/AIDS

Road-traffic accidents Hearing loss, adult onset All causes

1.

All causes 1.

143 574 59 423 382 458 188 174 107 552 78 206

All causes 1.

All causes 1.

Ischaemic heart disease Cerebrovascular disease

Trachea, bronchus and lung cancer Lower respiratory infections

Chronic obstructive pulmonary disease Alzheimer’s and other dementias Colon and rectum cancer Breast cancer

Self-inflicted injuries Prostate cancer

Unipolar depressive disorders Ischaemic heart disease

Chronic obstructive pulmonary disease Cerebrovascular disease

Alzheimer’s and other dementias Trachea, bronchus and lung cancer Alcohol-use disorders

Hearing loss, adult onset Self-inflicted injuries Road-traffic accidents 102 947

14 985 131 685 88 271 All causes

1.

All causes 1.

Cerebrovascular disease Ischaemic heart disease Inflammatory heart diseases Trachea, bronchus and lung cancer Diabetes mellitus

Colon and rectum cancer Self-inflicted injuries Liver cancer

Nephritis and nephrosis Cirrhosis of the liver

Cerebrovascular disease Unipolar depressive disorders Ischaemic heart disease Inflammatory heart diseases Osteoarthritis

Trachea, bronchus and lung cancer Perinatal conditions

Hearing loss, adult onset Self-inflicted injuries Vision disorders, age-related 34 894

649 408 63 065 Ischaemic heart disease

Lower respiratory infections Unipolar depressive disorders Perinatal conditions Cerebrovascular disease Diarrhoeal diseases Tuberculosis

Hearing loss, adult onset Anaemia

Diabetes mellitus

BULGARIACROATIACYPRUSCZECH REPUBLIC

Mortality DALYs

Member State

Causes Total

deaths

All causes 1.

All causes 1.

106 748 26 638

Ischaemic heart disease Cerebrovascular disease Unipolar depressive disorders Osteoarthritis

Diabetes mellitus Hearing loss, adult onset Alcohol-use disorders Hypertensive heart disease Vision disorders, age-related Trachea, bronchus and lung cancer

1 464 368 179 532 164 980 94 865

Ischaemic heart disease Cerebrovascular disease

Trachea, bronchus and lung cancer Colon and rectum cancer Cirrhosis of the liver Stomach cancer Breast cancer Self-inflicted injuries Lower respiratory infections Hypertensive heart disease

Cerebrovascular disease Ischaemic heart disease Unipolar depressive disorders Alcohol-use disorders

Trachea, bronchus and lung cancer Hearing loss, adult onset

Cirrhosis of the liver

Alzheimer’s and other dementias Road-traffic accidents

Chronic obstructive pulmonary disease All causes

1.

All causes 1.

709 409 77 915

All causes 1.

All causes 1.

Ischaemic heart disease Cerebrovascular disease Lower respiratory infections Road-traffic accidents

Trachea, bronchus and lung cancer Breast cancer

Colon and rectum cancer Nephritis and nephrosis Bladder cancer Stomach cancer

Unipolar depressive disorders Ischaemic heart disease Vision disorders, age-related Road-traffic accidents Hearing loss, adult onset Cataracts

Diabetes mellitus Cerebrovascular disease Lower respiratory infections Schizophrenia

108 491 7 476 All causes

1.

All causes 1.

Ischaemic heart disease Cerebrovascular disease

Trachea, bronchus and lung cancer Colon and rectum cancer Lower respiratory infections Breast cancer

Cirrhosis of the liver

Chronic obstructive pulmonary disease Falls

Self-inflicted injuries

Ischaemic heart disease Cerebrovascular disease Unipolar depressive disorders Alcohol-use disorders

Trachea, bronchus and lung cancer Hearing loss, adult onset Colon and rectum cancer Alzheimer’s and other dementias Chronic obstructive pulmonary disease Self-inflicted injuries

103 313 25 899 163 488 115 113 104 052 63 520 Ischaemic heart disease

Cerebrovascular disease Hypertensive heart disease Trachea, bronchus and lung cancer Colon and rectum cancer Diabetes mellitus Stomach cancer

Lower respiratory infections Cirrhosis of the liver Self-inflicted injuries

DENMARKESTONIAFINLANDFRANCE

Mortality DALYs

Member State

Ischaemic heart disease Cerebrovascular disease

Chronic obstructive pulmonary disease Trachea, bronchus and lung cancer Colon and rectum cancer Falls

Alzheimer’s and other dementias Breast cancer

Diabetes mellitus

Lower respiratory infections All causes

1.

All causes 1.

Unipolar depressive disorders Chronic obstructive pulmonary disease Ischaemic heart disease

Cerebrovascular disease Alcohol-use disorders

Trachea, bronchus and lung cancer Alzheimer’s and other dementias Hearing loss, adult onset Colon and rectum cancer Diabetes mellitus

750 197 61 059

Ischaemic heart disease Cerebrovascular disease

Trachea, bronchus and lung cancer Poisonings

Self-inflicted injuries Colon and rectum cancer Hypertensive heart disease Stomach cancer

Lower respiratory infections Inflammatory heart diseases

Ischaemic heart disease Cerebrovascular disease Unipolar depressive disorders Poisonings

Alcohol-use disorders Self-inflicted injuries Hearing loss, adult onset Road-traffic accidents Violence

Osteoarthritis All causes

1.

All causes 1.

264 152 33 180

All causes 1.

All causes 1.

Ischaemic heart disease Cerebrovascular disease Alzheimer’s and other dementias Lower respiratory infections Trachea, bronchus and lung cancer Self-inflicted injuries

Chronic obstructive pulmonary disease Colon and rectum cancer

Falls Breast cancer

Unipolar depressive disorders Ischaemic heart disease Cerebrovascular disease Alzheimer’s and other dementias Alcohol-use disorders

Self-inflicted injuries Hearing loss, adult onset Osteoarthritis

Trachea, bronchus and lung cancer Chronic obstructive pulmonary disease 48 461

667 725 72 348 All causes

1.

All causes 1.

Ischaemic heart disease Cerebrovascular disease

Trachea, bronchus and lung cancer Lower respiratory infections Colon and rectum cancer Alzheimer’s and other dementias Chronic obstructive pulmonary disease Breast cancer

Diabetes mellitus Falls

Unipolar depressive disorders Alcohol-use disorders

Alzheimer’s and other dementias Cerebrovascular disease Hearing loss, adult onset Ischaemic heart disease Road-traffic accidents

Trachea, bronchus and lung cancer Chronic obstructive pulmonary disease Self-inflicted injuries

499 040 45 501 761 929 398 770 288 825 259 266 253 702 248 323 245 691 243 306 205 199 174 870

100.0

Causes Causes

Table 4 contd

GEORGIAGERMANYGREECEHUNGARY

Mortality DALYs

Member State

Ischaemic heart disease Cerebrovascular disease Cirrhosis of the liver Diabetes mellitus

Trachea, bronchus and lung cancer Perinatal conditions

Breast cancer

Lower respiratory infections Stomach cancer

Tuberculosis All causes 1.

All causes 1.

Ischaemic heart disease Cerebrovascular disease Unipolar depressive disorders Perinatal conditions Osteoarthritis Drug-use disorders Cirrhosis of the liver Hearing loss, adult onset Diabetes mellitus

Vision disorders, age-related

892 192 163 411 122 449 61 490

Ischaemic heart disease Cerebrovascular disease

Trachea, bronchus and lung cancer Colon and rectum cancer

Chronic obstructive pulmonary disease Diabetes mellitus

Lower respiratory infections Breast cancer

Hypertensive heart disease Cirrhosis of the liver

Ischaemic heart disease Unipolar depressive disorders Alcohol-use disorders Cerebrovascular disease Hearing loss, adult onset Alzheimer’s and other dementias Trachea, bronchus and lung cancer Chronic obstructive pulmonary disease Cirrhosis of the liver

Osteoarthritis All causes

1.

All causes 1.

815 401 172 717 79 326 871 228 818 642 521 875 513 718 393 423 377 824 353 787 334 100 264 492 251 575

100.0

All causes 1.

All causes 1.

Cerebrovascular disease Ischaemic heart disease

Trachea, bronchus and lung cancer Colon and rectum cancer Upper respiratory infections Road-traffic accidents Liver cancer Breast cancer Stomach cancer

Chronic obstructive pulmonary disease

Cerebrovascular disease Ischaemic heart disease Unipolar depressive disorders Road-traffic accidents Hearing loss, adult onset Alzheimer’s and other dementias Trachea, bronchus and lung cancer Alcohol-use disorders

Diabetes mellitus Osteoarthritis 130 517 111 885 72 775 All causes

1.

All causes 1.

Ischaemic heart disease Cerebrovascular disease

Trachea, bronchus and lung cancer Cirrhosis of the liver

Colon and rectum cancer Hypertensive heart disease Falls

Self-inflicted injuries

Chronic obstructive pulmonary disease Breast cancer

Ischaemic heart disease Cerebrovascular disease Unipolar depressive disorders Cirrhosis of the liver Alcohol-use disorders

Trachea, bronchus and lung cancer Hearing loss, adult onset

Chronic obstructive pulmonary disease Self-inflicted injuries

Osteoarthritis 122 161

29 420 186 226 121 473 104 867 93 358

Causes Causes

ICELANDIRELANDISRAELITALY

Table 4 contd

Mortality DALYs

Member State

Ischaemic heart disease Cerebrovascular disease

Trachea, bronchus and lung cancer Alzheimer’s and other dementias Lower respiratory infections

Chronic obstructive pulmonary disease Colon and rectum cancer

Breast cancer Prostate cancer Pancreatic cancer All causes

1.

All causes 1.

Unipolar depressive disorders Ischaemic heart disease Cerebrovascular disease Alzheimer’s and other dementias Hearing loss, adult onset

Chronic obstructive pulmonary disease Trachea, bronchus and lung cancer Self-inflicted injuries

Alcohol-use disorders Road-traffic accidents

28 340

Ischaemic heart disease Lower respiratory infections Cerebrovascular disease

Trachea, bronchus and lung cancer Chronic obstructive pulmonary disease Colon and rectum cancer

Breast cancer Prostate cancer

Lymphomas, multiple myeloma Self-inflicted injuries

Unipolar depressive disorders Ischaemic heart disease Alcohol-use disorders Cerebrovascular disease

Chronic obstructive pulmonary disease Hearing loss, adult onset

Alzheimer’s and other dementias Road-traffic accidents

Asthma

Trachea, bronchus and lung cancer All causes

1.

All causes 1.

487 635 40 534

All causes 1.

All causes 1.

Ischaemic heart disease Diabetes mellitus Cerebrovascular disease Colon and rectum cancer Trachea, bronchus and lung cancer Breast cancer

Chronic obstructive pulmonary disease Nephritis and nephrosis

Lower respiratory infections Lymphomas, multiple myeloma

Unipolar depressive disorders Ischaemic heart disease Diabetes mellitus Hearing loss, adult onset Alzheimer’s and other dementias Perinatal conditions

Cerebrovascular disease Congenital anomalies Endocrine disorders Drug-use disorders 35 355

658 655 82 393 All causes

1.

All causes 1.

Ischaemic heart disease Cerebrovascular disease

Trachea, bronchus and lung cancer Hypertensive heart disease

Chronic obstructive pulmonary disease Diabetes mellitus

Colon and rectum cancer Lower respiratory infections Alzheimer’s and other dementias Breast cancer

Unipolar depressive disorders Ischaemic heart disease Cerebrovascular disease Alzheimer’s and other dementias Hearing loss, adult onset Diabetes mellitus

Trachea bronchus lung cancers Alcohol-use disorders Road-traffic accidents Osteoarthritis 570 710

92 928 464 873 450 953 385 564 304 193 272 459 253 447 238 299 227 530 182 555 177 068

100.0

Causes Causes

KAZAKHSTANKYRGYZSTANLATVIALITHUANIA

Mortality DALYs

Member State

Ischaemic heart disease Cerebrovascular disease Poisonings

Self-inflicted injuries Hypertensive heart disease

Chronic obstructive pulmonary disease Tuberculosis

Trachea bronchus lung cancers Lower respiratory infections Cirrhosis of the liver All causes

1.

All causes 1.

184 078 51 948

Ischaemic heart disease Cerebrovascular disease Poisonings

Unipolar depressive disorders Self-inflicted injuries Perinatal conditions Tuberculosis

Lower respiratory infections Violence

Chronic obstructive pulmonary disease

3 752 121 409 227 248 561 186 699 163 543 137 970 119 481 118 961 109 198 104 789 97 422

Ischaemic heart disease Cerebrovascular disease

Chronic obstructive pulmonary disease Perinatal conditions

Lower respiratory infections Cirrhosis of the liver Tuberculosis Stomach cancer Nephritis and nephrosis Self-inflicted injuries

Perinatal conditions Cerebrovascular disease Ischaemic heart disease Lower respiratory infections Unipolar depressive disorders Chronic obstructive pulmonary disease Congenital anomalies

Cirrhosis of the liver Tuberculosis Diarrhoeal diseases All causes

1.

All causes 1.

All causes 1.

All causes 1.

Ischaemic heart disease Cerebrovascular disease

Trachea, bronchus and lung cancer Self-inflicted injuries

Colon and rectum cancer Inflammatory heart diseases Stomach cancer

Road-traffic accidents Falls

Breast cancer

Ischaemic heart disease Cerebrovascular disease Unipolar depressive disorders Alcohol-use disorders Road-traffic accidents Inflammatory heart diseases Self-inflicted injuries Hearing loss, adult onset Osteoarthritis

Trachea, bronchus and lung cancer 33 451

482 223 60 445 All causes

1.

All causes 1.

Ischaemic heart disease Cerebrovascular disease Self-inflicted injuries

Trachea, bronchus and lung cancer Chronic obstructive pulmonary disease Colon and rectum cancer

Stomach cancer Road-traffic accidents Poisonings

Cirrhosis of the liver

Ischaemic heart disease Unipolar depressive disorders Cerebrovascular disease Self-inflicted injuries Road-traffic accidents Alcohol-use disorders Hearing loss, adult onset Osteoarthritis

Violence

Trachea, bronchus and lung cancer 41 060

625 222 77 874

Causes Causes

LUXEMBOURGMALTAMONACONETHERLANDS

Table 4 contd

Mortality DALYs

Member State

Ischaemic heart disease Cerebrovascular disease

Trachea, bronchus and lung cancer Colon and rectum cancer

Chronic obstructive pulmonary disease Lower respiratory infections

Breast cancer

Alzheimer’s and other dementias Cirrhosis of the liver

Self-inflicted injuries All causes

1.

All causes 1.

Unipolar depressive disorders Alcohol-use disorders Cerebrovascular disease Ischaemic heart disease Hearing loss, adult onset Road-traffic accidents

Alzheimer’s and other dementias Chronic obstructive pulmonary disease Trachea, bronchus and lung cancer Self-inflicted injuries

55 069

Ischaemic heart disease Cerebrovascular disease Lower respiratory infections Trachea, bronchus and lung cancer Colon and rectum cancer Diabetes mellitus Breast cancer

Chronic obstructive pulmonary disease Skin conditions

Nephritis and nephrosis

Ischaemic heart disease Unipolar depressive disorders Cerebrovascular disease Diabetes mellitus Hearing loss, adult onset Alzheimer’s and other dementias Chronic obstructive pulmonary disease Trachea, bronchus and lung cancer Alcohol-use disorders

Osteoarthritis All causes

1.

All causes 1.

All causes 1.

All causes 1.

Ischaemic heart disease Cerebrovascular disease

Trachea, bronchus and lung cancer Lower respiratory infections Colon and rectum cancer

Chronic obstructive pulmonary disease Endocrine disorders

Breast cancer Falls

Diabetes mellitus

Unipolar depressive disorders Alcohol-use disorders Hearing loss, adult onset Cerebrovascular disease Ischaemic heart disease Alzheimer’s and other dementias Chronic obstructive pulmonary disease Trachea, bronchus and lung cancer Road-traffic accidents

Endocrine disorders 261 All causes

1.

All causes 1.

Ischaemic heart disease Cerebrovascular disease

Trachea, bronchus and lung cancer Lower respiratory infections

Chronic obstructive pulmonary disease Alzheimer’s and other dementias Colon and rectum cancer Breast cancer

Diabetes mellitus Prostate cancer

Unipolar depressive disorders Ischaemic heart disease

Unipolar depressive disorders Ischaemic heart disease