Case Reports
70. Neuromuscul Disord . 2021 Sep 6;S0960-8966(21)00620-9. Online ahead of print.
MuSK not MNGIE: Atypical MuSK-antibody myasthenia presenting as a genetic disorder
Simon Thebault 1 , Ebrima Gibbs 2 , Pierre Bourque 3 , Doug McKim 3 , Kawan Rakhra 4 , Ari Breiner 3 , Hans Frykman 2 , Jodi Warman-Chardon 5
1 Department of Medicine, The Ottawa Hospital, Centre for Neuromuscular Disease and University of Ottawa, Canada. Electronic address: sthebault@toh.ca.
2 The University of British Columbia Neuroimmunology lab, Canada.
3 Department of Medicine, The Ottawa Hospital, Centre for Neuromuscular Disease and University of Ottawa, Canada.
4 Department of Diagnostic Imaging, The Ottawa Hospital and University of Ottawa, Canada.
5 Department of Medicine, The Ottawa Hospital, Centre for Neuromuscular Disease and University of Ottawa, Canada; Department of Genetics, Children's Hospital of Eastern Ontario Research Institute. Electronic address:
jwarman@toh.on.ca.
PMID: 34690051
DOI: 10.1016/j.nmd.2021.08.014
Keywords: Autoimmune diseases; EMG; Mitochondrial disorders; MuSK; Muscle disease; Myasthenia.
Published Erratum
71. Ther Adv Neurol Disord . 2021 Oct 29;14:17562864211049696. eCollection 2021.
Corrigendum to "Safety and effectiveness of eculizumab in Japanese patients with generalized myasthenia gravis: interim analysis of post-marketing surveillance"
No authors listed
PMID: 34733355
PMCID: PMC8559188
DOI: 10.1177/17562864211049696 Erratum for
Safety and effectiveness of eculizumab in Japanese patients with generalized myasthenia gravis: interim analysis of post-marketing surveillance.
Murai H, Suzuki S, Hasebe M, Fukamizu Y, Rodrigues E, Utsugisawa K. Ther Adv Neurol Disord. 2021 Mar
16;14:17562864211001995. doi: 10.1177/17562864211001995. eCollection 2021. PMID: 33796147 Free PMC article.
72. BMC Neurol . 2021 Nov 4;21(1):428. doi: 10.1186/s12883-021-02439-7.
Clinical features, treatment and prognosis of MuSK antibody-associated myasthenia gravis in Northwest China: a single-centre retrospective cohort study
Sijia Zhao # 1 , Kai Zhang # 2 , Kaixi Ren # 1 , Jiarui Lu 1 , Chao Ma 3 , Cong Zhao 4 , Zhuyi Li 5 , Jun Guo 6
1 Department of Neurology, Tangdu Hospital, Air Force Medical University, Xi'an, 710038, Shaanxi Province, China.
2 Department of Intensive Care Unit, Xi'an No.3 Hospital, Xi'an, 710018, Shaanxi Province, China.
3 Department of Cardiology, Tangdu Hospital, Air Force Medical University, Xi'an, 710038, Shaanxi Province, China.
4 Department of Neurology, Air Force Medical Center of PLA, Beijing, 100142, China.
5 Department of Neurology, Tangdu Hospital, Air Force Medical University, Xi'an, 710038, Shaanxi Province, China. lizhuyi62@163.com.
Bibliographie sur les maladies neuromusculaires Bibliography of neuromuscular disorders
n° 2021-11-1 du 22 octobre au 4 novembre 2021 (October 22 to november 4, 2021)
6 Department of Neurology, Tangdu Hospital, Air Force Medical University, Xi'an, 710038, Shaanxi Province, China. guojun_81@163.com.
PMID: 34732168
PMCID: PMC8567678
DOI: 10.1186/s12883-021-02439-7
Keywords: Azathioprine; Muscle-specific kinase; Myasthenia gravis; Rituximab; Tacrolimus.
73. Neurol Ther . 2021 Nov 2. doi: 10.1007/s40120-021-00292-x. Online ahead of print.
Risk Factors for Generalization in Patients with Ocular Myasthenia Gravis: A Multicenter Retrospective Cohort Study
Rong-Jing Guo # 1 , Ting Gao # 1 , Zhe Ruan # 1 , Hong-Yu Zhou # 2 , Feng Gao # 3 , Quan Xu 4 , Li-Ping Yu 5 , Song-Di Wu 6 , Tao Lei 7 , Huan-Huan Li 1 , Chao Sun 1 , Min Zhang 1 , Yan-Wu Gao 1 , Xiao-Dan Lu 1 , Yong-Lan Tang 1 , Bao-Li Tang 1 , Fei-Yan Huo 1 , Ying Zhu 1 , Zhu-Yi Li 8 , Ting Chang 9
1 Department of Neurology, Tangdu Hospital, The Fourth Military Medical University, Xi'an, 710038, China.
2 Department of Neurology, West China Hospital, Sichuan University, Chengdu, China.
3 Department of Neuroimmunology, Henan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, China.
4 Department of Thoracic Surgery, Jiangxi Provincial People's Hospital, Nanchang, China.
5 Department of Neurology, Xianyang First People's Hospital, Xianyang, China.
6 Department of Neurology, Xi'an No.1 Hospital, Xi'an, China.
7 Department of Neurology, Xi'an Fourth Hospital, Xi'an, China.
8 Department of Neurology, Tangdu Hospital, The Fourth Military Medical University, Xi'an, 710038, China.
lizhuyiafu@163.com.
9 Department of Neurology, Tangdu Hospital, The Fourth Military Medical University, Xi'an, 710038, China.
changting1981@163.com.
PMID: 34729706
DOI: 10.1007/s40120-021-00292-x
Keywords: Cox proportional hazards model; Generalization; Generalized myasthenia gravis; Ocular myasthenia gravis;
Risk factors.
74. Front Neurol . 2021 Oct 15;12:738813. doi: 10.3389/fneur.2021.738813. eCollection 2021.
A Comparison of Clinical, Electro-Diagnostic, Laboratory, and Treatment Outcome Differences in a Cohort of HIV-Infected and HIV-Uninfected Patients With Myasthenia Gravis
Kaminie Moodley 1 , Pierre L A Bill 1 , Vinod B Patel 1
1 Department of Neurology, University of KwaZulu-Natal, Durban, South Africa.
PMID: 34721269
PMCID: PMC8553930
DOI: 10.3389/fneur.2021.738813
Keywords: AIDS; HIV; IV cyclophosphamide (CY); Myasthenia Gravis; Plasma exchange (PLEX, PE); intravenous immunoglobulin (IVIG).
75. Front Neurol . 2021 Oct 13;12:736190. doi: 10.3389/fneur.2021.736190. eCollection 2021.
Effectiveness and Safety of Rituximab for Refractory Myasthenia Gravis: A Systematic Review and Single-Arm Meta-Analysis
Cong Zhao 1 , Meng Pu 2 , Dawei Chen 1 , Jin Shi 1 , Zhuyi Li 3 , Jun Guo 3 , Guangyun Zhang 1
1 Department of Neurology, Air Force Medical Center of PLA, Beijing, China.
2 Department of Hepatobiliary Surgery, Air Force Medical Center of PLA, Beijing, China.
3 Department of Neurology, Tangdu Hospital, Air Force Medical University, Xi'an, China.
PMID: 34721267
PMCID: PMC8548630
DOI: 10.3389/fneur.2021.736190
Keywords: effectiveness; meta-analysis; myasthenia gravis; refractory; rituximab.
Bibliographie sur les maladies neuromusculaires Bibliography of neuromuscular disorders
n° 2021-11-1 du 22 octobre au 4 novembre 2021 (October 22 to november 4, 2021)
76. Orphanet J Rare Dis . 2021 Oct 30;16(1):457. doi: 10.1186/s13023-021-02064-0.
Development of the Myasthenia Gravis (MG) Symptoms PRO: a case study of a patient-centred outcome measure in rare disease
Sophie Cleanthous 1 , Ann-Christin Mork 2 , Antoine Regnault 3 , Stefan Cano 1 , Henry J Kaminski 4 , Thomas Morel 5 6
1 Modus Outcomes, Letchworth Garden City, UK.
2 UCB S.A., Allée de la Recherche, 60, 1070, Brussels, Belgium.
3 Modus Outcomes, Lyon, France.
4 George Washington University, Washington, DC, USA.
5 UCB S.A., Allée de la Recherche, 60, 1070, Brussels, Belgium. Thomas.Morel@ucb.com.
6 KU Leuven, Leuven, Belgium. Thomas.Morel@ucb.com.
PMID: 34717694
PMCID: PMC8556940
DOI: 10.1186/s13023-021-02064-0
Keywords: Mixed methods psychometrics; Myasthenia gravis; Outcome; Patient-centred; Rare disease.
77. Asian Pac J Allergy Immunol . 2021 Oct 31. doi: 10.12932/AP-260521-1141. Online ahead of print.
Ocular manifestation and generalization after ocular onset in ocular myasthenia gravis: A 5-year analysis
Parinee Kemchoknatee 1 , Apisama Arepagorn 2 , Thansit Srisombut 2
1 Department of Ophthalmology, Rajavithi Hospital, Bangkok, Thailand.
2 Faculty of Medicine Rajavithi Hospital, Rangsit University, Bangkok, Thailand.
PMID: 34717528
DOI: 10.12932/AP-260521-1141
78. J Neuroimmune Pharmacol . 2021 Oct 29. doi: 10.1007/s11481-021-10030-7. Online ahead of print.
Increased Expression of CD95 in CD4 + Effector Memory T Cells Promotes Th17 Response in Patients with Myasthenia Gravis
Xiaoyu Huang # 1 , Jie Zhu # 1 2 , Tan Liu # 1 3 , Fengzhan Li 1 , Tingting Yang 1 , Hao Li 1 , Fei Chen 1 2 , Yong Zhang 4 , Yuzhong Wang 5 , Linlin Fu 6 , Chenghua Xiao 1 , Deqin Geng 7
1 Department of Neurology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.
2 Department of Neurology, Second Affiliated Hospital of Xuzhou Medical University, 32 Coal Construction Road, Quanshan District, Xuzhou, Jiangsu, China.
3 Department of Neurology, The First People's Hospital of Huzhou, Huzhou, Zhejiang, China.
4 Department of Neurology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.
zy20037416@163.com.
5 Department of Neurology, Affiliated Hospital of Jining Medical University, Jining, Shandong, China.
6 Department of Pathogenic Biology and Lab of Infection and Immunology, Xuzhou Medical University, Xuzhou, Jiangsu, China.
7 Department of Neurology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.
Gengdeqin_123@163.com.
PMID: 34716498
DOI: 10.1007/s11481-021-10030-7
Keywords: CD4+ TEM cells; CD95; Myasthenia gravis; Th17.
Published Erratum
79. Neurology . 2021 Oct 29;10.1212/WNL.0000000000013021. Online ahead of print.
Patient-Reported Symptom Severity in a Nationwide Myasthenia Gravis Cohort: Cross-sectional Analysis of the Swedish GEMG Study
No authors listed
PMID: 34716258
DOI: 10.1212/WNL.0000000000013021 Erratum for
Bibliographie sur les maladies neuromusculaires Bibliography of neuromuscular disorders
n° 2021-11-1 du 22 octobre au 4 novembre 2021 (October 22 to november 4, 2021)
Patient-Reported Symptom Severity in a Nationwide Myasthenia Gravis Cohort: Cross-sectional Analysis of the Swedish GEMG Study.
Petersson M, Feresiadou A, Jons D, Ilinca A, Lundin F, Johansson R, Budzianowska A, Roos AK, Kågström V, Gunnarsson M, Sundström P, Piehl F, Brauner S. Neurology. 2021 Aug 10;97(14):e1382-91. doi:
10.1212/WNL.0000000000012604. Online ahead of print. PMID: 34376512 Free PMC article.
MYOBASE LINK: https://www.myobase.org/index.php?lvl=notice_display&id=73050
80. Neurol Sci . 2021 Oct 28. doi: 10.1007/s10072-021-05652-x. Online ahead of print.
Serum irisin levels in patients with myasthenia gravis
Sheng-Nan Zhang # 1 , Qi Li # 1 , Qiu-Xia Zhang 1 , Tian-Xiao Gao 1 , Sheng-Hui Chang 1 , Da-Qi Zhang 2 , Lin-Jie Zhang 1 , Li Yang 3
1 Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China.
2 Department of Neurology, First Affiliated Hospital of Hainan Medical University, Haikou, China.
3 Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China. yangli2001@tmu.edu.cn.
PMID: 34709479
DOI: 10.1007/s10072-021-05652-x Keywords: ELISA; Irisin; Myasthenia gravis; Serum.
Review
81. BJA Educ . 2021 Nov;21(11):414-419. doi: 10.1016/j.bjae.2021.07.001. Epub 2021 Aug 19.
Perioperative management of myasthenia gravis P Daum 1 , J Smelt 1 , I R Ibrahim 1
1 St George's University Hospitals NHS Foundation Trust, London, UK.
PMID: 34707886
PMCID: PMC8520038 (available on 2022-11-01)
DOI: 10.1016/j.bjae.2021.07.001
Keywords: complications; myasthenia gravis; perioperative care.
82. Med Sci Monit . 2021 Oct 28;27:e933296. doi: 10.12659/MSM.933296.
Adverse Side Effects Associated with Corticosteroid Therapy: A Study in 39 Patients with Generalized Myasthenia Gravis
Stephen Johnson 1 , Nakul Katyal 2 , Naureen Narula 3 , Raghav Govindarajan 2
1 Department of Neurology, Brigham and Women's Hospital and Massachusetts General Hospital, Boston, MA, USA.
2 Department of Neurology, University of Missouri Health Care, Columbia, MO, USA.
3 Department of Pulmonary and Critical Care, Northwell Health - Staten Island University Hospital, New York City, NY, USA.
PMID: 34707081
DOI: 10.12659/MSM.933296
83. Ann Phys Rehabil Med . 2021 Oct 21;101593. doi: 10.1016/j.rehab.2021.101593. Online ahead of print.
Multidisciplinary rehabilitation is relevant in severe myasthenia gravis: an observation Maëva Cotinat 1 , Annie Verschueren 2 , Shahram Attarian 2 , Jean-Michel Viton 3 , Laurent Bensoussan 4
1 Aix Marseille Université, CNRS, INT UMR 7289, 13385 Marseille, France; APHM, Timone University Hospital, CHU Timone, Physical and Rehabilitation Medicine Department, 264 rue Saint Pierre, 13385 Marseille Cedex 05, France. Electronic address: maeva.cotinat@ap-hm.fr.
2 Reference Centre for neuromuscular diseases and ALS, Timone University Hospital, Aix-Marseille Université, CHU Timone, 264 rue Saint Pierre, 13385, Marseille Cedex 05, France.
3 Aix Marseille Université, CNRS, INT UMR 7289, 13385 Marseille, France; APHM, Timone University Hospital, CHU Timone, Physical and Rehabilitation Medicine Department, 264 rue Saint Pierre, 13385 Marseille Cedex 05, France.
4 Aix Marseille Université, CNRS, INT UMR 7289, 13385 Marseille, France; APHM, Timone University Hospital, CHU Timone, Physical and Rehabilitation Medicine Department, 264 rue Saint Pierre, 13385 Marseille Cedex 05, France; UGECAM Institut Universitaire de Réadaptation de Valmante Sud.
Bibliographie sur les maladies neuromusculaires Bibliography of neuromuscular disorders
n° 2021-11-1 du 22 octobre au 4 novembre 2021 (October 22 to november 4, 2021)
PMID: 34688914
DOI: 10.1016/j.rehab.2021.101593
Keywords: exercise; fatigue; multidisciplinary rehabilitation; myasthenia gravis; quality of life; respiratory training.
84. Muscle Nerve . 2021 Oct 23. doi: 10.1002/mus.27443. Online ahead of print.
Identifying a patient-centered outcome measure for a comparative effectiveness treatment trial in myasthenia gravis
Pushpa Narayanaswami 1 , Donald B Sanders 2 , Kathie Bibeau 3 , Andrew Krueger 4 , Jurgen Venitz 5 , Jeffrey T Guptill 2
1 Department of Neurology, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, Massachusetts, USA.
2 Department of Neurology, Duke University Medical Center, Durham, North Carolina, USA.
3 Myasthenia Gravis Foundation of America, Seattle, Washington, USA.
4 Accordant Health Services, Greensboro, North Carolina, USA.
5 Department of Pharmaceutics, Virginia Commonwealth University School of Pharmacy, Richmond, Virginia, USA.
PMID: 34687458
DOI: 10.1002/mus.27443
Keywords: adverse events; comparative effectiveness; myasthenia gravis; observational study; outcome measure;
treatment.
85. Neurol Ther . 2021 Dec;10(2):1103-1125. doi: 10.1007/s40120-021-00285-w. Epub 2021 Oct 23.
The Lived Experience of Myasthenia Gravis: A Patient-Led Analysis Nancy Law # 1 , Kelly Davio # 2 , Melissa Blunck 3 , Dawn Lobban 4 , Kenza Seddik 5 6
1 Patient Author, MG Patient Advocate, Parker, CO, USA.
2 Patient Author, MG Patient Advocate, Richmond, London, UK.
3 UCB Pharma, Smyrna, GA, USA.
4 Envision Pharma Group, Cheshire, UK.
5 UCB Pharma, Paris, France. Kenza.seddik@ucb.com.
6 , 420 Rue d'Estienne d'Orves, 92700, Colombes, France. Kenza.seddik@ucb.com.
PMID: 34687427
PMCID: PMC8540870
DOI: 10.1007/s40120-021-00285-w
Keywords: Lived experience; Myasthenia gravis; Patient perspective; Qualitative.
86. Neurol Sci . 2021 Oct 22. doi: 10.1007/s10072-021-05599-z. Online ahead of print.
Characteristics of myasthenia gravis in elderly patients: a retrospective study
Yi Li 1 , Xiaohua Dong 1 , Zhibin Li 1 , Yuyao Peng 1 , Wanlin Jin 1 , Ran Zhou 1 , Fei Jiang 1 , Liqun Xu 1 , Zhaohui Luo 1 , Huan Yang 2
1 Department of Neurology, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan, 410000, People's Republic of China.
2 Department of Neurology, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan, 410000, People's Republic of China. yangh69@126.com.
PMID: 34677704
DOI: 10.1007/s10072-021-05599-z
Keywords: Clinical characteristics; Elderly; Myasthenia gravis; Outcome.