• Aucun résultat trouvé

III. RESULTATS

2. LA PERIODE DU REPERAGE AU DIAGNOSTIC

2.1 Modalités de repérage des difficultés

O efeito da redução dos níveis de citoqueratina 18 em célula HeLa no ciclo biológico do T. cruzi foi comparado através da análise de variância (ANOVA) de uma via e posteriormente utilizando-se o teste Tukey HSD, disponíveis na página http://faculty.vassar.edu/lowry/VassarStats.htm.

5.32. Análise densitométrica.

Para a análise densitométrica do Westhern Blot foi utilizado o programa ImageJ, disponível na página http://rsb.info.nih.gov/ij/.

AGÜERO F, VERDÚN RE, FRASCH ACC & SÁNCHEZ DO. (2000) A random sequencing approach for the analysis of the Trypanosoma cruzi genome: general structure, large gene and repetitive DNA families, and gene discovery. Genome Res, 10:1996-2005.

ALENCAR BCG, ARAÚJO AFS, PENIDO MLO, GAZZINELLI RT & RODRIGUES MM. (2007) Cross-priming of long lived protective CD8+ T cells against Trypanosoma cruzi infection: importance of a TLR9 agonist and CD4+ T cells. Vaccine, 25:6018-27.

ALMEIDA-DE-FARIA M, FREYMULLER E, COLLI W & ALVES MJM. (1999) Trypanosoma cruzi: characterization of an intracellular epimastigote-like form. Exp Parasitol 92:263-74.

ALMEIDA IC, FERGUSON MA, SCHENKMAN S & TRAVASSOS LR. (1994) Lytic anti-alpha-galactosyl antibodies from patients with chronic Chagas’disease recognizes novel O-linked oligossaccharides on mucin-like glycosil-phosphatidylinositol-anchored glycoproteins of Trypanosoma cruzi. Biochem J, 304:793-802.

ANDRADE LO & ANDREWS NW. (2004) Lysosomal fusion is essential for the retention of Trypanosoma cruzi inside host cells. J Exp Med, 200:1135-43. ANDREWS NW. (1990) The acid-active hemolysin of Trypanosoma cruzi. Exp

Parasitol, 71:242-44.

ANDREWS NW. (2002) Lysosomes and the plasma membrane: trypanosomes reveal a secret relationship. J Cell Biol, 158:389-94.

AÑEZ N, CRISANTE G, da SILVA FM, ROJAS A, CARRASCO H, UMEZAWA ES, STOLF AMS, RAMIREZ JL & TEIXEIRA MMG. (2004) Predominance of lineage I among Trypanosoma cruzi isolates from Venezuelan patientes with different clinical profiles of acute Chagas´s disease. Trop Med Int Health, 9:1319-26.

ARAÚJO AFS, DE ALENCAR BCG, VASCONCELO JRC, HIYANE MI, MARINHO CRF, PENIDO MLO, BOSCARDIN SB, HOFT DF, GAZZINELLI RT & RODRIGUES MM. (2005) CD8+-T-Cell dependent control of Trypanosoma cruzi infection in a highly susceptible mouse strain after immunization with recombinant proteins based on Amastigote Surface Protein 2. Infec Immun., 73:6017-25.

ARAYA JE, CANO MI, YOSHIDA N & DA SILVEIRA JF. (1994) Cloning and characterization of a gene for the stage-specific 82-kDa surface antigen of metacyclic trypomastigotes of Trypanosoma cruzi. Mol Biochem Parasitol, 65:161-9

ARNHOLDT AC, PIUVEZAM MR, RUSSO DM, LIMA AP, PEDROSA RC, REED SG & SCHARFSTEIN J. (1993) Analysis and partial epitope mapping of human T cell responses to Trypanosoma cruzi cysteinyl proteinase. J Immunol, 151:3171-9.

ATAYDE VD, CORTEZ M, SOUZA R, DA SILVEIRA JF & YOSHIDA N. (2007) Expression and cellular localization of molecules of the gp82 family in Trypanosoma cruzi metacyclic trypomastigotes. Infect Immun, 75:3264-70.

ATWOOD III JA, WEATHERLY DB, MINNING TA, BUNDY B, CAVOLA C, OPPERDOES FR, ORLANDO R & TARLETON RL. (2005) The Trypanosoma cruzi proteome. Science, 309:473-76.

BANGS JD, UYETAKE L, BRICKMAN MJ, BALBER AE & BOOTHROYD JC. (1993) Molecular cloning and cellular localization of a BIP homologue in Trypanosoma cruzi. Divergent ER retention signals in a lower eukaryote. J Cell Sci, 105:1101-13.

BARRETTO MP. (1979) Trypanosoma cruzi e a Doenca de Chagas. Brener, Z., Andrade Z.A., eds, Rio de Janeiro, 89-151, Guanabara Koogan.

BARRETT MP, BURCHMORE RJS, STICH A., LAZZARI JO, FRASCH AC & CAZZULO JJ. (2003) The trypanosomiases. The Lancet, 362:1469-80.

BEHR C, SARTHOU JL, ROGIER C, TRAPE JF, DAT MH, MICHEL JC, ARIBOT G, DIEYE A, CLAVERIE JM, DRUIHLE P & DUBOIIS P. (1992) Antibodies and reactive T cells against the malaria heat-shock protein Pf72/Hsp70-1 and derived peptides in individuals continously exposed to Plasmodium falciparum. J Immunol, 149:3321-30.

BHATIA V, SINHA M, LUXON B & GARG N. (2004) Utility of the Trypanosoma cruzi sequence database for identification of potential vaccine candidates by in silico and in vitro screening. Infect Immun, 72:6245-54.

BÖHME U & CROSS GAM. (2001) Mutational analysis of the variant surface glycoprotein GPI-anchor signal sequence in Trypanosoma brucei. Journal of Cell Science, 115:805-16.

BONFA E, VIANA VS, BARRETO AC, YOSHINARI NH & COSSERMELLI W. (1993) Autoantibodies in Chagas’disease. An antibody cross-reactive with human and Trypanosoma cruzi ribossomal proteins. J Immunol, 150:3917-23. BOSCARDIN SB, KINOSHITA SS, FUJIMURA AE & RODRIGUES MM. (2003)

Immunization with cDNA expressed by amastigotes of Trypanosoma cruzi elicits protective immune response against experimental infection. Infect Immun, 71:2744-57.

BRISSE S, VERHOEF J & TIBAYRENC M. (2001) Characterization of large and small subunit r RNA and mini-exon genes further supports the distinction of six Trypanosoma cruzi lineages. Int J Parasitol, 31:1218-26.

BURLEIGH BA & WOOLSEY AM. (2002) Cell signaling and Trypanosoma cruzi invasion. Cell Microb, 4:701-11.

BUSCAGLIA CA, CAMPO VA, FRASCH ACC & Di NOIA JM. (2006) Trypanosoma cruzi surface mucins: host-dependent coat diversity. Nature, 4:229-36.

CAMPETELLA O, HENRIKSSON J, ASLUND L, FRASCH AC, PETTERSSON U & CAZZULO JJ. (1992) The major cysteine proteinase (cruzipain) from Trypanosoma cruzi is encoded by multiple polymorphic tandemly organized genes located on different chromosomes. Mol Biochem Parasitol, 50:225-34. CAMPO VA, BUSCAGLIA CA, Di NOIA JM & FRASCH ACC. (2006)

Immunocharacterization of the mucin-type proteins from intracellular stage of Trypanosoma cruzi. Microbes Infect, 8:401-09.

CANÇADO JR & BRENER Z. (1979) Terapêutica. In Trypanosoma cruzi e Doença de Chagas. Brener, Z. e Andrade, Z., eds, 362-424, Guanabara Koogan.

CAPETANAKI Y, BLOCK RJ, KOULOUMENTA A, MAVROIDIS M & PSARRAS S. (2007) Muscle intermediate filaments and their links to membranes and membranous organelles. Exp Cell Res, 313:2063-76

CERQUEIRA GC, DaROCHA WD, CAMPOS PC, ZOUAIN CS & TEIXEIRA SMR. (2005) Analysis of expressed sequence tags from Trypanosoma cruzi amastigotes. Mem Inst Oswaldo Cruz, 100:385-89.

CHAGAS C. (1909) Nova tripanosomiase humana. Estudos sobre a morfologia e o ciclo evolutivo do Cchizotrypanum n. gen, n. sp., agente etiologico de nova entidade morbida do homem. Mem. Inst. Oswaldo Cruz, 1:159-218

CHAMPMAN MD, BAGGALEY RC, GODFREY-FAUSSET PF, MALPAS TJ, WHITE G, CANESE J & MILES MA. (1984) Trypanosoma cruzi from the Paraguayan Chaco: isoenzyme profiles of strains isolated at Makthlawaiya. Protozool, 31:482-86.

CHILLER TM, SAMUDIO MA & ZOULEK G. (1990) IgG antibody reactivity with Trypanosoma cruzi and Leishmania antigens in sera of patients with Chagas’disease and leishmaniasis. Am J Trop Med Hyg, 43:650-56.

CLASER C, ESPÍNDOLA NM, SASSO G, VAZ AJ, BOSCARDIN SB & RODRIGUES MM. (2007) Immunologically relevant strain polymorphism in the Amastigote Surface Protein 2 of Trypanosoma cruzi. Microbes Infect, 20079:1011-19.

COLLI W. (1993) Trans-sialidase: a unique enzyme activity discovered in the protozoan Trypanosoma cruzi. Faseb J, 7:1257-64.

COURA JR, BARRETTO TV & NARANJO MA. (1994) Ataque de populações humanas por triatomíneos silvestres no Amazonas: uma nova forma de transmissão da infecção chagásica. Rev Soc Bras Med Trop, 27:251-53.

COURA JR, JUNQUEIRA AC, FERNANDES O, VALENTE SA & MILES MA. (2002) Emerging Chagas disease in Amazonian Brazil. Trends Parasitol., 18:171-76.

COURA JR. (2003) Tripanossomose, doença de Chagas. Ciênc Cult (São Paulo), 55:30-33.

CROSS GA & TAKLE GB. (1993) The surface trans-sialidase family of Trypanosoma cruzi. Annu Rev Microbiol, 47:385-411.

DaROCHA WD, BARTHOLOMEU DC, MACÊDO CDS, HORTA MF, CUNHA- NETO E, DONELSON JE & TEIXEIRA SMR. (2002) Characterization of cDNA clones encoding ribonucleoprotein antigens expressed in Trypanosoma cruzi amastigotes. Parasitol Res, 88:292-300.

DaROCHA WD, SILVA RA, BARTHOLOMEU DC, PIRES SF, FREITAS JM, MACEDO AM, VAZQUEZ MP, LEVIN MJ & TEIXEIRA SMR. (2003) Expression of exogenous genes in Trypanosoma cruzi: improving vectors and eletroporation protocols. Parasitol Res, 92:113-20.

DE ANDRADE CR, KIRCHHOFF LV, DONELSON JE & OTSU K. (1992) Recombinant Leishmania hsp90 and hsp70 are recognized by sera from visceral

leishmaniasis patients but not Chagas’disease patients. J Clin Microbiol, 30:330-35.

DIAS JCP. (2006) Notas sobre o Trypanosoma cruzi e suas características bio- ecológicas, como agente de enfermidades transmitida por alimentos. Rev Soc Bras Med Trop, 39:370-73.

Di NOIA JM, D’ORSO I, SÁNCHEZ DO & FRASCH ACC. (2000) AU-rich elements in the 3’ untranslated region of a new mucin-type gene family of Trypanosoma cruzi confers mRNA instability and modulates translation efficiency. J Biol Chem, 275:10218-27.

Di NOIA JM, D’ORSO I, ASLUND DO, SÁNCHEZ DO & FRASCH ACC. (1998) The Trypanosoma cruzi mucin family is transcribed from hundreds of genes having hypervariable regions. J Biol Chem, 273:10843-50.

EL SAYED NM, MYLER PJ, BARTHOLOMEU DC, NILSSON D, AGGARWAL G, TRAN AN, GHEDIN E, WORTHEY EA, DELCHER AL, BLANDIN G, WESTENBERGER SJ, CALER E, CERQUEIRA GC, BRANCHE C, HAAS B, ANUPAMA A, ARNER E, ASLUND L, ATTIPOE P, BONTEMPI E, BRINGAUD F, BURTON P, CADAG E, CAMPBELL DA, CARRINGTON M, CRABTREE J, DARBAN H, DA SILVEIRA JF, DE JONG P, EDWARDS K, ENGLUND PT, FAZELINA G, FELDBLYUM T, FERELLA M, FRASCH AC, GULL K, HORN D, HOU L, HUANG Y, KINDLUND E, KLINGBEIL M, KLUGE S, KOO H, LACERDA D, LEVIN MJ, LORENZI H, LOUIE T, MACHADO CR, McCULLOCH R, McKENNA A, MIZUNO Y, MOTTRAM JC, NELSON S, OCHAYA S, OSOEGAWA K, PAI G, PARSONS M, PENTONY M, PETTERSSON U, POP M, RAMIREZ JL, RINTA J, ROBERTSON L, SALZBERG SL, SANCHEZ DO, SEYLER A, SHARMA R, SHETTY J, SIMPSON AJ, SISK E, TAMMI MT, TARLETON R, TEIXEIRA S, VAN AKEN S, VOGT C, WARD P N, WICKSTEAD B, WORTMAN J, WHITE O, FRASER CM, STUART KD & ANDERSSON B. (2005) The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas’ disease. Science, 309:409-15.

ENGMAN DM, DRAGON EA & DONELSON JE. (1990) Human humoral immunity to hsp70 during Trypanosoma cruzi infection. J Immunol, 144:3987-3991. ENGMAN DM, KRAUSE KH, BLUMIN JH, KIM KS, KIRCHHOFF LV &

DONELSON JE. (1989) A novel flagellar Ca+2-binding protein in trypanosomes. J Biol Chem, 264:18627-31.

FELICIANGELI MD, CAMPBELL-LENDRUM D, MARTINEZ C, GONZALES D, COLEMAN P & DAVIES C. (2003) Chagas disease control in Venezuela: lessons for the Andean region and beyond. Trends Parasitol, 19:44-49.

FERNANDES AB, NEIRA I, FERREIRA AT & MORTARA RA. (2006) Cell invasion by Trypanosoma cruzi amastigotes of distinct infectivities: studies on signaling pathways. Parasitol Res, 100:59-68.

FERNANDES O, MANGIA RH, LISBOA CV, PINHO AP, MOREL CM, ZINGALES B, CAMPBELL DA & JANSEN AM. (1999) The complexity of the sylvatic cycle of Trypanosoma cruzi in Rio de Janeiro state (Brazil) revealed by the non-transcribed spacer of the mini-exon gene. Parasitology, 118:161-66.

FERNANDES O, STURM NR, DERRE R & CAMPBELL DA. (1998) The mini-exon gene: a genetic marker for zymodeme III of Trypanosoma cruzi. Mol Biochem Parasitol, 95:129-33.

FOLGUEIRA C & REQUENA JM. (2007) A postgenomic view of the heat shock proteins in kinetoplastids. Microbiol Rev, 31:359-77.

FRALISH BH & TARLETON RL. (2003) Genetic immunization with LYT1 or a pool of trans-sialidase genes protects mice from lethal Trypanosoma cruzi infection. Vaccine, 21:3070-80.

FRASCH AC. (2000) Functional diversity in the trans-sialidase and mucin families in Trypanosoma cruzi. Parasitol Today, 16:282-6.

GARG N, POSTAN M, MENSA-WILMOT K & TARLETON R. (1997) Glycosylphosphatidylinositol are required for the development of Trypanosoma cruzi amastigotes. Infect Immun, 65:4055-60.

GARG N & TARLETON RL. (2002) Genetic immunization elicits antigen-specific protective immune responses and decreases disease severity in Trypanosoma cruzi infection. Infect Immun, 70:5547-55.

GILBERT S, LORANGER A & MARCEUAU N. (2004) Keratins modulate c- Flip/extracellular signal-regulated kinase 1 and 2 antipoptotic signaling in simple epithelial cells. Mol Cell Biol, 24:7072-81.

GODSEL LM, TIBBETTS RS, OLSON CL, CHAUDOIR BM & ENGMAN DM. (1995) Utility of recombinant flagellar calcium-binding protein for serodiagnosis of Trypanosoma cruzi infection. J Clin Microb, 33:2082-85. GONZALEZ A, LERNER TJ, HUECAS M, SOSA-PINEDA B, NOGUEIRA N &

LIZARDI PM. (1985) Apparent generation of a segmented mRNA from two separate tandem gene families in Trypanosoma cruzi. Nucleic Acids Res., 13:5789-04.

GONZALEZ J, ARAGUTH MF & YOSHIDA N. (1991) Resistance to acute Trypanosoma cruzi infection resulting from immunization of mice with a 90- kilodalton antigen from metacyclic trypomastigotes. Infect Immun, 59:863-7. GURTLER RE. (2005) Incidence of Trypanosoma cruzi infection among children

following domestic reinfestation after insecticide spraying in rural northwestern Argentina. Am. J. Trop. Med. Hyg., 73:95–103

HOARE CA & WALLACE FG. (1966) Developmental stages of trypanosomatid flagellates: a new terminology. Nature, 212:1385-86.

KAHN S, VAN VOORHIS WC & EISEN H. (1990) The major 85-kD surface antigen of the mammalian form of Trypanosoma cruzi is encoded by a large heterogeneous family of simultaneously expressed genes. J Exp Med, 172:589- 97.

KOBAYASHI, T, SASAKI, Y, OSHIMA, Y, YAMAMOTO, H, MITA, H, SUZUKI, H, TOYOTA, M, TOKINO, T, ITOH, F, IMAI, K, SHINOMURA, Y (2006) Activation of the ribosomal protein L13 gene in human gastrointestinal cancer. Int. J. Mol. Med. 18:161-70.

KRAUTZ GM, PETERSON JD, GODSEL LM, KRETTLI AU & ENGMAN DM. (1998) Human antibody responses to Trypanosoma cruzi 70-kD heat-shock proteins. Am J Trop Med Hyg, 58:137-43.

LASAKOSVITSCH F, GENTIL LG, dos SANTOS MRM, da SILVEIRA JF & BARVIÉRI CLM. (2003) Cloning and characterization of a cystein proteinase gene expressed in amastigotes of Leishmania (L.) amazonensis.Int J Parasitol, 33:445-54.

LEVIN MJ, MESRI E, BENAROUS R, LEVITUS G, SCHIJMAN A, LEVY- YEYATI P, CHIALE A, RUIZ AM, KAHN A & ROSENBAUM MB. (1989) Identification of major Trypanosoma cruzi antigenic determinants in chronic Chagas’ heart disease. Am J Trop Med Hyg, 41:530-38.

LINDQUIT S & CRAIG EA. (1988) The heat-shock proteins. Annu Rev Genet, 22:631-677.

LORANGER A, DUCLOS S, GRENIER A, PRICE J, WILSON-HEINER M, BARIBAULT H & MARCEAU N. (1997) Simple epithelium keratins are required for maintenance of hepatocyte integrity. Am J Pathol, 151:1673-83. LOW HP, SANTOS MA, WIZEL B & TARLETON RL. (1998) Amastigote surface

proteins of Trypanosoma cruzi are targets for CD8+ CTL. J Immunol, 160:1817-23.

LOW HP & TARLETON RL. (1997) Molecular cloning of the gene encoding the 83 kDa amastigote surface protein and its identification as a member of the Trypanosoma cruzi sialidase superfamily. Mol Biochem Parasitol, 88:137-49. MACEDO AM, MACHADO CR, OLIVEIRA RP & PENA SDJ. (2004) Trypanosoma

cruzi: Genetic strcture of populations and relevance of genetic variability to the pathogenesis of Chagas disease. Mem Inst Oswaldo Cruz, 99:1-12.

MACEDO AM & PENA SDJ. (1998) Genetic variability of Trypanosoma cruzi: implications for the pathogenesis of Chagas disease. Parasitol Today, 14:119- 23.

MACHADO AV, CARDOSO JE, CLASER C, RODRIGUES MM, GAZZINELLI RT & BRUÑA-ROMERO O. (2006) Longo-term protective immunity induced against Trypanosoma cruzi infection after vaccination with recombinant adenoviruses encoding Amastigote Surface Protein-2 and Trans-Sialidase. Hum Gene Ther., 17:1-11.

MAGDESIAN MH, GIORDANO R, ULRICH H, JULIANO MA, JULIANO L, SCHUMACHER RI, COLLI W & ALVES MJ. (2001) Infection by Trypanosoma cruzi. Identification of a parasite ligand and its host cell receptor. J Biol Chem, 276:19382-9.

MAGDESIAN MH, TONELLI RR, FESSEL MR, SILVEIRA MS, SCHUMACHER RI, LINDEN R, COLLI W & ALVES MJM. (2006) A conserved domain of the gp85/trans-sialidase family activates host cell extracellular signal-regulated kinase and facilitates Trypanosoma cruzi infection. Exp Cell Res, 313:210-18. MANNING-CELA, CORTÉS A, GONZÁLEZ-REY E, BORIS WCV, SWINDLE J &

GONZÁLEZ A. (2001) LYT1 protein is required for efficient in vitro infection by Trypanosoma cruzi. Infect. Immun., 69:3916-23.

MANOEL-CAETANO FS & SILVA AE. (2007) Implications of genética variability of Trypanosoma cruzi for the pathogenesis of Chagas disease. Cad Saúde Pública, 23:2263-74.

MARCEAU N, LORANGER A, GILBERT S, DAIGIE N & CHAMPETIER S. (2001) Keratin-mediated resistance to stress and apoptosis in simple epithelial cells in relation to health and disease. Biochem Cell Biol, 79:543-55.

MIETTINEN M & FETSCH JF. (2000) Distribution of keratins in normal endothelial cells and a spectrum of vacular tumors: implications in tumor diagnosis. Hum Pathol, 31:1062-7.

MILLAR AE, WLEKLINSKI-LEE M & KAHN SJ. (1999) The surface protein superfamily of Trypanosoma cruzi stimulates a polarized Th1 response that becomes anergic. J Immunol, 162:6092-9.

MILES MA, CEDILLOS RA, POVOA MM, de SOUZA AA, PRATA A & MACEDO V. (1981) Do radically dissimilar Trypanosoma cruzi strains (zymodemes) cause Venezuelan and Brazilian forms of Chagas disease? Lancet, 1:1338-40. MILES MA, SOUZA A, POVOA M, SHAW JJ, LAINSON R & TOYE PJ. (1978)

Isozymic heterogeneity of Trypanosoma cruzi in the first autochtonous patients with Chagas disease in Amazonian Brazil. Nature, 272:819-21.

MILES MA, LANHAM SM, DE SOUZA AA & POVOA M. (1980) Further enzymic characters of Trypanosoma cruzi and their evaluation for strain identification. Trans R Soc Trop Med and Hyg, 74:221-42.

MORTARA RA, ANDREOLLI WK, TANIWAKI NN, FERNANDES AB, DA SILVA CV, FERNANDES MCDC, L’ABBATE C & DA SILVA S. (2005) Mammalian cell invasion and intracellular trafficking by Trypanosoma cruzi infective forms. An Acad Bras Cienc, 77:77-94.

MOSER D, DOUMBO O & KLINKERT MQ. (1990) The humoral response to heat shock protein 70 in human and marine Schistosoma mansoni. Parasite Immunol, 12:341-352.

MUKHERJEE S, HUANG H, PETKOVA SB, ALBANESE C, PESTELL RG, BRAUNSTEIN VL, CHRIST GJ, WITTNER M, LISANTI MP, BERMAN JW, WEISS LM & TANOWITZ HB. (2004) Trypanosoma cruzi infection activates extracellular signal-regulated kinase in cultured endothelial and smooth muscle cells. Infect Immun, 72:5274-82.

NDE PN, SIMMONS KJ, KLESHCHENKO YY, PRATAP S, LIMA MF & VILLALTA F. (2006) Silencing of laminin -1 gene blocks Trypanosoma cruzi infection. Infect Immun, 74:1643-48.

OKURA M, FANG J, SALTO ML, SINGER RS, DOCAMPO R & MORENO SNJ. (2005) A lipid-modified phosphoinositide-specific phopholipase C (TcPI-PLC) is involved in differentiation on trypomastigotes to amastigotes of Trypanosoma cruzi. J Biol Chem, 280:16235-43.

OLSON CL, NADEAU KC, SULLIVAN MA, WINQUIST AG, DONELSON JE, WALSH CT & ENGMAN DM. (1994) Molecular and biochemical comparison of the 70-kDa heat shock proteins of Trypanosoma cruzi. J Biol Chem, 269:3868-74.

OSHIMA RG. (2002) Apoptosis and keratin intermediate filaments. Cell Death Different, 9:486-92.

OUAISSI A, AGUIRRE T, PLUMAS-MARTY B, PIRAS M, SCHÖNECK R, GRAS-MASSE H, TAIBI A, LOYENS M, TARTAR A, CAPRON A, et al.

(1992) Cloning and sequencing of a 24-kDa Trypanosoma cruzi specific antigen released in association with membrane vesicles and defined by a monoclonal antibody. Biol Cell, 75:11-17.

PAIS FS, DaROCHA WD, CAMPOS P, CUNHA-NETO E & TEIXEIRA SMR. (2002) Human chagasic responses against T. cruzi recombinant antigens derived from ribonucleproteic complexes. Proceedings of the XXIX Annual Meeting on Basic Research in Chagas Disease Caxambú, MG.

PAN AA & MCMAHON-PRATT D. (1989) Amastigote and epimastigote stage- specific components of Trypanosoma cruzi characterized by using monoclonal antibodies. Purification and molecular characterization of an 83-kilodalton amastigote protein. J Immunol, 143:1001-8.

PEDROSO A, CUPOLILLO E & ZINGALES B. (2003) Evaluation of Trypanosoma cruzi hybrid stocks based on chromosomal size variation. Mol Biochem Parasitol, 129:79-90.

PEREIRA-CHIOCCOLA VL, ACOSTA-SERRANO A, de ALMEIDA IC, FERGUSON MA, SOUTO-PADRON T, RODRIGUES MM, TRAVESSOS LR & SCHENKMAN S. (2000) Mucin-like molecules form a negatively charged coat that protects Trypanosoma cruzi trypomastigotes from killing by human anti--galactosyl antibodies. J Cell Sci, 113:1299-07.

PREVIATO JO, JONES C, GONÇALVES LP, WAIT R, TRAVASSOS LR & MENDONÇA-PREVIATO L. (1994) O-glycosidically linked N- acetylglucosamine-bound oligosaccharides from glycoproteins of Trypanosoma cruzi. Biochem J, 301:151-59.

PREVIATO JO, JONES C, XAVIER MT, WAIT R, TRAVASSOS LR, PARODI AJ & MENDONÇA-PREVIATO L. (1995) Structural characterization of the major glycosylphosphatidylinositol membrane-anchored glycoprotein from epimastigote forms of Trypanosoma cruzi Y-strain. J Biol Chem, 270:7241-50. REQUENA JM, SOTO M, GUZMAN F, MAEKELT A, NOYA O, PATARROYO

ME & ALONSO C. (1993) Mapping of antigenic determinants of the T. cruzi hsp70 in chagasic and healthy individuals. Mol Immunol, 30:1115-21.

ROGGENTIN P, ROTHE B, KAPER JP, GALEN J, LAWRISUK L, VIMR ER & SCHAUER R. (1989) Conserved sequences in bacterial and viral sialidases. Glycoconj J., 6:349-53.

ROTHSTEIN N & RAJAN TV. (1991) Characterization of an hsp 70 gene from the human filarial parasite, brugia malayi (Nematoda). Mol Biochem Parasitol, 49:229-37.

RUIZ RC, FAVORETO S JR., DORTA ML, OSHIRO MEM, FERREIRA AT, MANQUE PM & YOSHIDA N. (1998) Infectivity of Trypanosoma cruzi isolates is associated with differential expression of surface glycoproteins with differential Ca2+ signalling activity. Biochem. J., 330:505-11.

RUIZ RC, RIGONI VL, GONZALES J & YOSHIDA N. (1993) The 35/50 kDa surface antigen of Trypanosoma cruzi metacyclic trypomastigotes, an adhesion molecule involved in host cell invasion. Parasite Immunol, 15:121-25.

SANTOS MA, GARG N & TARLETON RL. (1997) The identification and molecular characterization of Trypanosoma cruzi amastigote surface protein-1, a member of the trans-sialidase gene super-family. Mol Biochem Parasitol, 86:1-11.

SATELLITE MEETING. (1999) Recommendations from a satellite meeting. Mem

Inst Oswaldo Cruz, 94:429-32.

SCHARFSTEIN J, SCHMITZ V, MORANDI V, CAPELLA MMA, LIMA APCA, MORROT A, JULIANO L & MÜLLER-ESTERL W. (2000) Host cell invasion by Trypanosoma cruzi is potentiated by activation of bradykinin B2 receptors. J Exp Med, 192:1289-99.

SCHENKMAN S, FERGUSON MA, HEISE N, de ALMEIDA ML, MORTARA RA & YOSHIDA N. (1993) Mucin-like glycoproteins linked to the membrane by glycosylphosphatidyl inositol anchor are the major acceptors of sialic acid in a reaction catalyzed by trans-sialidase in metacyclic forms of Trypanosoma cruzi. Mol Biochem Parasitol, 59:293-303.

SCHENKMAN S, KUROSAKI T, RAVETCH JV & NUSSENZWEIG V. (1992) Evidence for the participation of the Ssp-3 antigen in the invasion of nonphagocytic mammalian cells by Trypanosoma cruzi. J Exp Med, 175:1635- 41.

SCHENKMAN S, ROBBINS ES & NUSSENZWEIG V. (1991) Attachment of Trypanosoma cruzi to mammalian cells requires parasite energy, and invasion can be independent of the target cell cytoskeleton. Infect Immun, 59:645-54. SCHNAPP AR, EICKHOFF CS, SIZEMORE D, CURTISS R, 3RD & HOFT DF.

(2002) Cruzipain induces both mucosal and systemic protection against Trypanosoma cruzi in mice. Infect Immun, 70:5065-74.

SCHOFIELD CJ, JANNIN J & SALVATELLA R. (2006) The future of Chagas disease control. Trends Parasitol., 22:583-88.

SEARIE S, McCROSSAN MV & SMITH DF. (1993) Expression of a mitochondrial stress protein in the protozoan parasite Leishmania major. J Cell Sci, 204:1091- 100.

SECRETARIA DE VIGILÂNCIA EM SAÚDE, MINISTÉRIO DA SAÚDE. Doença de Chagas aguda relacionada a ingestão de caldo de cana em Santa Catarina.

http://www.anvisa.gov.br/divulga/notícias/2005/240305_nota.pdf.

SERRANO AA, SCHENKMAN S, YOSHIDA N, MEHLERT A, RICHARDSON JM & FERGUSON MAJ. (1995) The lipid structure of the glycosylphosphatidylinositol-anchored mucin-like sialic acid acceptors of Trypanosoma cruzi changes during parasite differentiation from epimastigotes

Documents relatifs