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[PDF] Top 20 Transforming growth factor-beta and fibrosis.

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Transforming growth factor-beta and fibrosis.

Transforming growth factor-beta and fibrosis.

... Abstract Transforming growth factor-β (TGF-β), a prototype of multifunctional cytokine, is a key regulator of extracellular matrix (ECM) assembly and ...cells, and to stimulate the ... Voir le document complet

8

Regulation of Connective Tissue Growth Factor and Cardiac Fibrosis by an SRF/MicroRNA-133a Axis

Regulation of Connective Tissue Growth Factor and Cardiac Fibrosis by an SRF/MicroRNA-133a Axis

... Myocardial fibrosis contributes to the remodeling of heart and the loss of cardiac function leading to heart ...transcription factor implicated in the regulation of a large vari- ety of genes ... Voir le document complet

20

Rôle du facteur de croissance transforming growth factor beta-1 (TGF[beta]1) dans la synthèse d'oestradiol par les follicules ovariens bovins

Rôle du facteur de croissance transforming growth factor beta-1 (TGF[beta]1) dans la synthèse d'oestradiol par les follicules ovariens bovins

... Rôle du facteur de croissance transforming growth factor beta- 1 (TGF3 1) dans la synthèse d’oestradiol par les follicules ovariens bovinsG. par Yan Ouellette.[r] ... Voir le document complet

195

Advancing osteochondral tissue engineering: bone morphogenetic protein, transforming growth factor, and fibroblast growth factor signaling drive ordered differentiation of periosteal cells resulting in stable cartilage and bone formation in vivo.

Advancing osteochondral tissue engineering: bone morphogenetic protein, transforming growth factor, and fibroblast growth factor signaling drive ordered differentiation of periosteal cells resulting in stable cartilage and bone formation in vivo.

... plates and incubated at 37 °C in 95% humidity for 3 ...ECM and to develop cell-to-cell, cell-to-matrix, and cell-to-plastic interactions in a three-dimensional environment for the course of 28 ... Voir le document complet

13

Transforming Growth Factor-β Signaling Plays a Pivotal Role in the Interplay Between Osteosarcoma Cells and Their Microenvironment

Transforming Growth Factor-β Signaling Plays a Pivotal Role in the Interplay Between Osteosarcoma Cells and Their Microenvironment

... Verrecchia* and Françoise Rédini UMR1238 INSERM, Université de Nantes, PHY-OS, “Bone Sarcomas and Remodeling of Calcified Tissues”, Medical School, Nantes, France Osteosarcomas are the most frequent form of ... Voir le document complet

12

Transforming Growth Factor-beta and Interleukin-1beta Signaling Pathways Converge on the Chemokine CCL20 Promoter.

Transforming Growth Factor-beta and Interleukin-1beta Signaling Pathways Converge on the Chemokine CCL20 Promoter.

... Transforming Growth Factor- ␤ and Interleukin-1␤ Signaling Pathways Converge on the Chemokine CCL20 Promoter * Received for publication, December 6, 2014, and in revised form, April ... Voir le document complet

12

Transforming growth factor-beta1-mediated Slug and Snail transcription factor up-regulation reduces the density of Langerhans cells in epithelial metaplasia by affecting E-cadherin expression

Transforming growth factor-beta1-mediated Slug and Snail transcription factor up-regulation reduces the density of Langerhans cells in epithelial metaplasia by affecting E-cadherin expression

... skin and mucosal ...epithelium and that the low number of LCs observed in EpM correlates with the down-regulation of cell-surface ...that transforming growth factor- ␤1 is not only ... Voir le document complet

19

[Transforming growth factor-betas: smad signaling and roles in physiopathology]

[Transforming growth factor-betas: smad signaling and roles in physiopathology]

... Transforming Growth Factor-  s: signaling and physio-pathological roles Summary Transforming Growth Factor-  (TGF-  ) family members are multifunctional peptide ... Voir le document complet

13

Cyclic adenosine 3',5'-monophosphate-elevating agents inhibit transforming growth factor-beta-induced SMAD3/4-dependent transcription via a protein kinase A-dependent mechanism.: Inhibition of SMAD-dependent transcription by cAMP

Cyclic adenosine 3',5'-monophosphate-elevating agents inhibit transforming growth factor-beta-induced SMAD3/4-dependent transcription via a protein kinase A-dependent mechanism.: Inhibition of SMAD-dependent transcription by cAMP

... the Transforming Growth Factor-  (TGF-  ) family of growth factors ...proteins, and the TGF-  ) is initiated by binding of the ligands to transmembrane receptor serine/threonine ... Voir le document complet

27

Mammalian transforming growth factor-betas: Smad signaling and physio-pathological roles.

Mammalian transforming growth factor-betas: Smad signaling and physio-pathological roles.

... 80s, Transforming Growth Factor-b (TGF-b) has emerged as a family of growth factors involved in essential physiological processes, including embryonic development, differentiation, tissue ... Voir le document complet

11

Transforming Growth Factor Beta 1 Activation, Storage, and Signaling Pathways in Idiopathic Pulmonary Fibrosis in Dogs.

Transforming Growth Factor Beta 1 Activation, Storage, and Signaling Pathways in Idiopathic Pulmonary Fibrosis in Dogs.

... Transforming growth factor b1 is produced as an inactive form, the small latent complex, which is the active mature TGF-b1 peptide bound to its propep- ...17,18 and amb8 19 and by ... Voir le document complet

10

Controlled Delivery of Transforming Growth Factor β1 by Self-Assembling Peptide Hydrogels Induces Chondrogenesis of Bone Marrow Stromal Cells and Modulates Smad2/3 Signaling

Controlled Delivery of Transforming Growth Factor β1 by Self-Assembling Peptide Hydrogels Induces Chondrogenesis of Bone Marrow Stromal Cells and Modulates Smad2/3 Signaling

... 4 and Alan ...deliver transforming growth factor b1 (TGF-b1) to en- capsulated bone-marrow-derived stromal cells (BMSCs) for cartilage tissue engineering applications using two different ... Voir le document complet

11

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en fr Role of the small heat shock protein alphaB-crystallin in pulmonary fibrosis and its implication in the signaling pathway of the Transforming Growth Factor béta1 Rôle de la petite protéine de choc thermique alphaB crystallin dans la fibrogénèse pulmonaire et son implication dans la voie de signalisation du transforming growth factor - béta1

... pulmonary fibrosis (IPF) is a devastating disease characterized by the proliferation of myofibroblasts and extracellular-matrix (ECM) accumulation in ...IPF and is responsible for myofibroblast ... Voir le document complet

294

Transforming Growth Factor-β and Axl Induce CXCL5 and Neutrophil Recruitment in Hepatocellular Carcinoma

Transforming Growth Factor-β and Axl Induce CXCL5 and Neutrophil Recruitment in Hepatocellular Carcinoma

... SNU449-T and HLF-T cells ...ng/mL and 0.125 ng/mL TGF-β and analyzed for migratory ...ng/mL and 1 ng/mL showed a concentration-dependent reduction of the migrated area ...50% and 65%, ... Voir le document complet

33

Breast cancer-derived transforming growth factor-β and tumor necrosis factor-α compromise interferon-α production by tumor-associated plasmacytoid dendritic cells

Breast cancer-derived transforming growth factor-β and tumor necrosis factor-α compromise interferon-α production by tumor-associated plasmacytoid dendritic cells

... upregulated and translocated in the nucleus after 3-hr stimulation with Flu virus ...#7 and #9 or TGF-b1 1 TNF-a ...expression and activation of the transcription factor IRF-7, leading to ... Voir le document complet

9

Opposite Effects of Transforming Growth Factor-β Activation and Rho-Associated Kinase Inhibition on Human Trophoblast Migration in a Reconstituted Placental-Endometrial Coculture System

Opposite Effects of Transforming Growth Factor-β Activation and Rho-Associated Kinase Inhibition on Human Trophoblast Migration in a Reconstituted Placental-Endometrial Coculture System

... trophoblast and matrix, have been used to study trophoblast migration and invasion ex ...described and proven powerful research tools ...origins and means of immortalization of these cell ... Voir le document complet

12

Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo.

Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo.

... somatic loss-of-function mutations of the Ptch-1 gene (25), responded to TGF-β with significant upregulation of both Gli2 and Gli1 expression, with kinetics similar to those observed in non Gorlin-related cells. ... Voir le document complet

27

Transforming Growth Factor-Beta (TGFβ) Signaling Pathway in Cholangiocarcinoma

Transforming Growth Factor-Beta (TGFβ) Signaling Pathway in Cholangiocarcinoma

... remodeling and inflammation, which modulate the activity of signaling pathways involved in tumor onset and progression [ 10 , 11 ...expression and/or activation of key cytokines, tyrosine kinases, ... Voir le document complet

18

La régulation de l'apoptose des ostéoclastes humains par des facteurs locaux de l'os l'ostéoprotégérine et le "transforming growth factor-beta

La régulation de l'apoptose des ostéoclastes humains par des facteurs locaux de l'os l'ostéoprotégérine et le "transforming growth factor-beta

... Ceci est suivi par le recrutement d'autres précurseurs ostéoblastiques pour former une nouvelle couche d'os et recouvrir les ostéocytes (Huang et al., 2007).. A) Le[r] ... Voir le document complet

130

Diagnostic value of interleukine-6, transforming growth factor-beta 1 and vascular endothelial growth factor in malignant pleural effusions.

Diagnostic value of interleukine-6, transforming growth factor-beta 1 and vascular endothelial growth factor in malignant pleural effusions.

... patients and malignant pleural effusions in ...group and 66 ± 13 years in the malignant ...cancer and one unknown primary ...carcinoma and one small cell cancer) and mesothelioma was ... Voir le document complet

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