[PDF] Top 20 Thymic stroma is required for the development of human T cell lineages in vitro
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Thymic stroma is required for the development of human T cell lineages in vitro
... 1 Palacios, R and Pelkonen, J. Human T-cell precursors' involvement of the interleukin 2 pathway in the generation of mature T cells Immunol. In Immunodeficiency Springer, Berlin 4 WHO R[r] ... Voir le document complet
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HTLV-1 propels thymic human T cell development in "human immune system" Rag2-/- IL-2R γc-/- Mice
... Alteration of early haematopoietic development is thought to be responsible for the onset of immature leu- kemias and ...T cell Leukemia Virus type 1) is able not ... Voir le document complet
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Coupling of melanocyte signaling and mechanics by caveolae is required for human skin pigmentation
... feature of caveolae in many cell types in vitro and in vivo 25 , 28 .... In this context, caveolae were recently shown to couple mechanosensing with mechanosignaling ... Voir le document complet
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Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium.
... differentiation of the Paneth and goblet cell ...along the enterocyte (a, b) and enteroendocrine (c, d) lineages is not ...affected. The goblet cell population, ... Voir le document complet
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Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development.
... factors in the mouse pancreas Regulatory factor X (Rfx) proteins are transcription factors conserved from ...survey of mammalian genomes has identified seven Rfx genes in mouse and ... Voir le document complet
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Development and characterization of a human three-dimensional chondrosarcoma culture for in vitro drug testing
... that the microenvironment of a solid tumor can have on drug behavior are well documented, particularly as regards drug distribution (diffusion homogeneity and gradients) in the tumor, and ... Voir le document complet
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The transformer2 gene in Musca domestica is required for selecting and maintaining the female pathway of development
... Mdtra2 is essential for female development in Musca In Drosophila, the tra2 gene plays an important role in female ...assists the tra gene in setting ... Voir le document complet
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ZFPIP/Zfp462 is maternally required for proper early Xenopus laevis development.
... induce cell death and are thus deleterious for embryos. To study the impact of ZFPIP MOs on cell division and/or cell death in the xenopus embryo, we performed two ... Voir le document complet
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Transforming growth factor-β1 is the predominant isoform required for breast cancer cell outgrowth in bone
... capable of establishing lesions in TGF-b1-deficient mice compensate by upregulating the expression of TGF-b isoforms within the tumor Using an immunohistocytochemical approach, we ... Voir le document complet
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Sororin pre-mRNA splicing is required for proper sister chromatid cohesion in human cells.
... (2013) The landscape of somatic mutations in Down syndrome-related myeloid ...Acetylation of Smc3 by Eco1 is required for S phase sister chromatid cohesion in both ... Voir le document complet
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Population variability in the generation and thymic selection of T-cell repertoires
... correlations in various biologi- cal or clinical ...tions, for example after vaccination or infection [24, 25]. In such a context clone sizes may be crucial to identify the underlying ... Voir le document complet
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Development of thymic regulatory T cells during human immunodeficiency virus (HIV) infection
... People living with chronic human immunodeficiency virus (HIV) infection have increased Treg frequencies in peripheral blood and lymphoid tissues. TGF-~-mediated fibrosis [r] ... Voir le document complet
170
A cell wall‐associated polysaccharide is required for bacteriophage adsorption to the Streptococcus thermophilus cell surface
... 2 Supplementary Figure S1. Differences in wild-type and mutant cell pellets formed after overnight incubation. Clockwise from top left: ST64987 WT; BIM3; BIM8, BIM4. Supplementary Table S1. Efficiencies ... Voir le document complet
5
Phosphorylation of bovine leukemia virus Tax protein is required for in vitro transformation but not for transactivation.
... proteins of the oncovirinae viruses are phosphorylated transcriptional activators that exhibit oncogenic ...potential. The role of phosphorylation in their functional activities remains ... Voir le document complet
12
Bisphenol S Impaired Human Granulosa Cell Steroidogenesis In Vitro
... result is inconsistent with previous data in animal models, where BPS exposure increases oestradiol secretion in rat GC [43], ewe GC [44] and cow GC ...above, the fact that HGC were only ... Voir le document complet
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Expression of CD44 molecules and CD44 ligands during human thymic fetal development: expression of CD44 isoforms is developmentally regulated
... In this study, we have found that CD44 mAbs against all CD44 isoforms reacted with thymic fibroblasts, thymocytes and TE cells from the time of first colonization of the thymus by stem c[r] ... Voir le document complet
10
Dppa3 / Pgc7 / stellais a maternal factor and is not required for germ cell specification in mice
... Generation of Dppa3-deficient animals. A, Schematic representation of genomic ablation of ...Dppa3. The gene's four exons are shown; non-coding regions of the first and last ... Voir le document complet
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Human mesenchymal stem cell co-culture modulates the immunological properties of human intervertebral disc tissue fragments in vitro
... proliferation in co-culture, but in their presence IgG pro- duction was constantly ...doubling of IgG may correspond to the activation of the already present and mature ... Voir le document complet
12
TCR-MHC class II interaction is required for peripheral expansion of CD4 cells in a T cell-deficient host
... candidate for such a regulatory system would be the MHC molecules of the ...affinity for self MHC class II molecules would be allowed to survive and/or proliferate following transfer, ... Voir le document complet
6
Dihydropyrimidine Accumulation Is Required for the Epithelial-Mesenchymal Transition
... drivers of the EMT program can be modulated through inhibition of metabolic enzymes such as ...to the chemotherapeutic agent 5-FU, but the physiologic role of this enzyme ... Voir le document complet
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