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[PDF] Top 20 The hedgehog pathway and ocular developmental anomalies

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The hedgehog pathway and ocular developmental anomalies

The hedgehog pathway and ocular developmental anomalies

... on the model system studied, and are deficient in trafficking from endosomes to the ciliary membrane, thereby potentially affecting the levels of the non-specific SHH co-receptor, LRP2, ... Voir le document complet

23

Modulation of the Suppressor of fused protein regulates the Hedgehog signaling pathway in Drosophila embryo and imaginal discs.

Modulation of the Suppressor of fused protein regulates the Hedgehog signaling pathway in Drosophila embryo and imaginal discs.

... Su(fu) and Fu act antagonistically in the Hh pathway as negative and positive effectors, respectively, (Alves et ...modulate the effects of Su(fu) over-expression, we overexpressed ... Voir le document complet

21

Cilia, ciliopathies and hedgehog-related forebrain developmental disorders

Cilia, ciliopathies and hedgehog-related forebrain developmental disorders

... In the mouse, the role of Shh as a morphogen to specify cell fate has been extensively studied in the spinal cord ( Ribes and Briscoe 2009 ; Sasai and Briscoe 2012 ...in the ... Voir le document complet

20

Sonic hedgehog mediates a novel pathway of PDGF-BB-dependent vessel maturation

Sonic hedgehog mediates a novel pathway of PDGF-BB-dependent vessel maturation

... using the ELISA Kit "Mouse Sonic Hedgehog N-Terminus Quantikine" (R&D ...ECs and NG2 + MC in the cornea model was performed with anti- PDGF-B subunit antibody (Santa ...(BMA) ... Voir le document complet

23

Conifer somatic embryogenesis: from understanding the developmental pathway to the clonal propagation

Conifer somatic embryogenesis: from understanding the developmental pathway to the clonal propagation

... bons and longer. They are elongated by the elongase complex in the endoplasmic reticulum and are incorporated into four major lipid pools (triacylglycerols, waxes, phospholipids, complex ... Voir le document complet

59

Developmental neurocognitive pathway of psychosis proneness and the impact of cannabis use

Developmental neurocognitive pathway of psychosis proneness and the impact of cannabis use

... remain the best predictors of functional and social outcome (Kalkstein et ...Despite the fact that, more than a hundred years ago, with Kraepelin and Bleuler, schizophrenia was characterized ... Voir le document complet

243

Hedgehog theory via Euler calculus

Hedgehog theory via Euler calculus

... that the study of i h in the particular case n + 1 = 2 and h 2 C 2 S 1 ; R was the main ingredient in the resolution of the uniqueness conjecture of ...14], the author ... Voir le document complet

28

The cAMP pathway and the control of adrenocortical development and growth

The cAMP pathway and the control of adrenocortical development and growth

... the medullocortical boundary that expressed both X-zone (20 αHSD) (Hershkovitz et ...2007) and ZF (Akr1b7) specific markers (Aigueperse et ...of the normal ...continuous and autonomous ... Voir le document complet

16

Ocular metrics for detecting attentional tunnelling

Ocular metrics for detecting attentional tunnelling

... from the control ...S1 and S2, which correspond to autonomous guidance phases, are also homogeneous with a similar distribution of the state ratios for the two ...in ocular activity is ... Voir le document complet

12

Ocular inflammation induces trigeminal pain, peripheral and central neuroinflammatory mechanisms

Ocular inflammation induces trigeminal pain, peripheral and central neuroinflammatory mechanisms

... showing the percentage of the area covered by immunoreactive nerve fibers in different culture ...1β and IL-6 mRNA gene expression after exposure to BAC ... Voir le document complet

47

Shedding Light on the b to s Anomalies

Shedding Light on the b to s Anomalies

... on the relative size of these processes (pure scalar and Z 0 -mediated) one can then distinguish several ...of the fermion pairs for χχ ∗ . Therefore, under the fairly reasonable assumption ... Voir le document complet

10

Seasonal variations in the diet and food selection of the Algerian hedgehog Atelerix algirus

Seasonal variations in the diet and food selection of the Algerian hedgehog Atelerix algirus

... The highest prey species diversity was found in the Coleoptera order (100 species recorded) and the highest species occurrence was found in Hymenoptera (65% of the prey items, mainly r[r] ... Voir le document complet

1

The developmental polarity and morphogenesis of a single cell

The developmental polarity and morphogenesis of a single cell

... summarizes the two main currents of thought regarding the concept of cell polarity: one that is based on purely morphological considerations, and another with a more physiological perspective ... Voir le document complet

308

Defining the phenotype of FHF1 developmental and epileptic encephalopathy

Defining the phenotype of FHF1 developmental and epileptic encephalopathy

... facilitate the recognition of the phenotypic spectrum of that specific genetic DEE ...on the long arm of chromosome 3 (3q28-q29) and ...report the largest series of patients with ... Voir le document complet

21

Seasonal variations in the diet and food selection of the Algerian hedgehog Atelerix algirus

Seasonal variations in the diet and food selection of the Algerian hedgehog Atelerix algirus

... : The Algerian hedgehog Atelerix algirus is an insectivorous ...However, the exact composition of its natural diet remains largely undetermined, especially in relation to seasonal variations in food ... Voir le document complet

1

The hedgehog receptor patched is involved in cholesterol transport.

The hedgehog receptor patched is involved in cholesterol transport.

... In the second part of this report, we sought to demonstrate that Ptc could be responsible for the reduction of the cholesterol concentration in the environment of Smo by pumping cholesterol ... Voir le document complet

12

The developmental genetics of Hirschsprung's disease

The developmental genetics of Hirschsprung's disease

... in the male genital ridge where it functions as the key genetic switch for sex determination in mammals ...was the first SOX gene identified (47), and conferred its name to the family ... Voir le document complet

14

Molecular Layer Interneurons of the Cerebellum: Developmental and Morphological Aspects

Molecular Layer Interneurons of the Cerebellum: Developmental and Morphological Aspects

... recognizable, the identification of the other classes of dendrites would require ...for the time being there are no selective markers to distinguish basket from stellate ...case, the almost ... Voir le document complet

68

Asthma and genes encoding components of the vitamin D pathway

Asthma and genes encoding components of the vitamin D pathway

... investigate the long-term effects of inhaled anti-inflammatory medica- tions in children with mild to moderate asthma ...in the present analy- ses. This represents the subset non-Hispanic with CAMP ... Voir le document complet

21

Endogenous Sonic Hedgehog limits inflammation and angiogenesis in the ischaemic skeletal muscle of mice

Endogenous Sonic Hedgehog limits inflammation and angiogenesis in the ischaemic skeletal muscle of mice

... To further confirm this result, we performed in vitro assays using cultured macrophages. We first found that Shh recombinant protein had no effect on Gli1 or Gli2 mRNA expression (Supplemental Figure 4A-B). Nevertheless, ... Voir le document complet

26

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