... Ribosomalproteins are synthesized in the cytoplasm, before nuclearimport and assemblywithribosomal RNA ...coordination of nucleocytoplasmic transport ...
... Preparation of 5S rRNA. The DNA encoding 5S rRNA was amplified from genomic DNA of C. thermophilum. The sequence of the 5S rDNA from C. thermophilum is: 5’- ...
... generate proteins from mRNA templates. The biogenesis of eukaryotic ribosomes is an outstandingly complex process, in which around 80 ribosomalproteins and four ribosomal RNAs are ...
... identification of several proteins that interact with newly synthesized r-proteins and/or escort them to their ribosomeassembly ...each of these proteins ...
... preparation of DNA and RNA duplexes, for giving me insight into ribosomalproteins and their manipulation, and for being always available for a ...some of my results in the Peterman lab in the ...
... functions of these GTPases in ribosomeassembly. Incorporation of L27 or L36 is not likely to be the essential function(s) of RbgA, YsxC, or YphC, as L27 and L36 are dispensable for ...
... other ribosomalproteins, Rps3 import occurs mainly via the classical importin α /β (Kap60/Kap95) dependent ...associated with the ribosome-free Rps3/ Rps3/Yar1 complex in ...N-domain ...
... The nuclear export receptor Xpo1p forms distinct complexes with NES transport substrates and the yeast Ran binding protein 1 ...a nuclearimport receptor for ribosomeassembly ...
... The ribosome is responsible for the final step of decoding genetic information into ...correct assemblyof ribosomes is a fundamental task for all living ...construction of the ...
... Most ribosomalproteins, besides containing in many cases a globular domain, are made up of long extensions that mostly penetrate into the interior and stabilize the tertiary structure of rRNA ...
... consists of a conserved body and a eukaryote-specific N-terminal ...role of the N-terminal extension of the yeast S31 ...deletion of this extension partially impairs cell growth and 40S ...
... sensory-ribosomalproteins uL16, bL27, uL5, bL33 literally “innervate” the three key A, P and E-tRNA sites while uL4, uL22 and uL23 sense the interior of the peptide exit tunnel 32 through their ...
... Finally, of the genes involved in stress responses, it is striking that most of the genes listed in Supplemental Data Sets 3 and 4 are induced by three major stresses: cold, heat, and UV-B ...that ...
... incubated for 0.5 hours, 1.5 hours, or 3.0 hours and were separated by native polyacrylamide gel electrophoresis (PAGE) and Coomassie stained. As can be seen in Figure 5, the[r] ...
... Switzerland Importofnuclear-encoded precursor proteins from the cytosol is an essential step in chloroplast biogenesis that is mediated by protein translocon complexes at the inner and outer ...
... lectin with a well-defined carbohydrate binding activity and ...S197 of SNA-I, which is critical for the binding to sialic acid in the Neu5Ac(α2-6)Gal/GalNAc sequence of 2-6-sialyllactose, is ...
... characterized nuclearimport receptor of the karyopherin-β family after Importin-β, but certain aspects of its functions in cells are still puzzling or are just recently ...identification ...
... within ribosomal protein ...down-regulation of the pRPs while the cRPs have a much less coordinated profile and are globally only slightly affected by the TOR inactivation (Figure ...role of TOR in ...
... epidemics of influenza A virus are a major cause of severe illness and are of high socio-economic rele- ...design of effective antiviral therapies, a detailed knowledge of pathways ...
... small proteins that are most often partly or fully disordered in the absence of their binding partners? The present review is focused on the role of structural disorder in the early steps of ...