[PDF] Top 20 Studies of MHC class I antigen presentation & the origins of the immunopeptidome
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Studies of MHC class I antigen presentation & the origins of the immunopeptidome
... at the systems-level, MAP generation is regulated by numerous features of transcripts and proteins that affect translation and proteasomal ...features of the 5'UTR such as shorter length, ... Voir le document complet
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en fr Immunomodulators of the Major Histocompatibility Complex Class I (MHC-I) Antigen Presentation Pathway with Antitumor Properties Immunomodulateurs de la voie de présentation par le complexe majeur d'histocompatibilité de classe I (CMH-I) aux propriétés anti-tumorales
... CMH I Nous avons observé que l’effet d’IP2 est dépendant du système immunitaire et que le traitement induit la prolifération d’une population de LT CD8+ réactive contre un épitope immunogène exprimé à partir d’un ... Voir le document complet
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Systems biology of the human MHC class I immunopeptidome
... by studies showing that peptide production ceased 30 minutes after inhibition of protein synthesis, suggesting that mature protein turnover is too slow to contribute significantly to the peptide pool ... Voir le document complet
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Molecular characterization of the contribution of autophagy to antigen presentation using quantitative proteomics
... increases MHC Class I presentation of mitochondrial antigens Autophagy is not limited to the clearance of intracellular components, but also plays important roles in both ... Voir le document complet
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The Evolutionary Origins of Hierarchy
... composition of sub-modules—is ubiquitous in bio- logical networks, including neural, metabolic, ecological, and genetic regulatory networks, and in human-made systems, such as large organizations and the ... Voir le document complet
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Neurons are MHC Class I-Dependent Targets for CD8 T Cells upon Neurotropic Viral Infection
... recognition of peptide-MHC I complexes is essential to elicit CTL effector functions, it has long been considered that neurons were spared from CD8 T cell attack because they did not express ... Voir le document complet
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Expression of EPHRIN-A1, SCINDERIN and MHC class I molecules in head and neck cancers and relationship with the prognostic value of intratumoral CD8+ T cells.
... thick) of tumors were fixed in formol 4%, transferred in Citrate Buffer pH = 6 (MM France, T/T0050) in decloaking chamber for 20 min, blocked with blocking buffer (Dako, Glostrup, Denmark; X0909) and stained ... Voir le document complet
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L'idéologie dans <i>Yes Minister</i> et <i>The Thick of It</i> : la politique britannique revue et corrigée par la <i>middle class</i>
... Les journalistes, parfaitement évités par Sir Humphrey mais plus souvent rencontrés par Tucker (du fait de sa position de chef de la communication), sont présentés comme des nuisibles : loin de l'enthousiasme héroïque ... Voir le document complet
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Presentation of The price of robustness
... to the nominal value a_ij in the interval [a_ij- â_ij, a_ij + ...Row i -> J_i coefficients subject to uncertainty Gamma_i = parameter to adjust the robustness of the proposed ... Voir le document complet
12
The Origins of the Syrian Insurrection
... consisting of “traditional, estate- owning Sunni notables and Christian entrepreneurs” against previously dominated minority groups (including ethnic and religious minorities as well as poor rural ...antagonisms, ... Voir le document complet
7
Cross-reactivity between tumor MHC class I-restricted antigens and an enterococcal bacteriophage
... with the PSMB4 cancer epitope and affects human anticancer immune ...analysis of CD8 + tumor-infiltrating lymphocytes (from tumors treated as in ...tumor. The graphs assemble the results ... Voir le document complet
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Carrier-induced, hapten-specific suppression: a problem of antigen presentation?
... after the initiation of treatment, and levels of specific Abs were measured in individual ...sera. The data in Figure 2 show that, as expected, the production of the ... Voir le document complet
12
On the origins of the Finnis-Sinclair potentials
... 4. The Seventies (1970) and early Eighties; François Ducastelle and the second moment interaction model After computing the cohesive energy of a solid, the next idea naturally was to ... Voir le document complet
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Presentation of the Unit of Geomatics of the University of Liege
... • Many algorithms devoted to linear features extraction are proposed in literature but : – They have limited capabilities in dense and complex environments, such as the urban milieu where a large number of ... Voir le document complet
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Melanosomal targeting sequences from gp100 are essential for MHC class II-restricted endogenous epitope presentation and mobilization to endosomal compartments
... and MHC class II ...in the COOH terminus (last 70 ...expressing MHC class I and class II molecules, revealed that specific deletions in COOH terminus resulted in decreased ... Voir le document complet
10
FRT presentation of the Onsager algebras
... types of non-standard classical Yang-Baxter algebras associated with one of the simplest affine Kac-Moody algebra c sl 2 , and their explicit relations with the Onsager ...that the ... Voir le document complet
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The archaeal origins of the eukaryotic translational system
... that the eukaryotic cell incor- porated its modern translational machinery from a crenar- chaeal ancestor at about the same time as the probable pro- karyotic bottleneck noted ...besides the ... Voir le document complet
10
Mining the resource of cross-presentation
... in the future to restore immune surveillance by anti-suppressive agents and thera- peutic ...direct presentation require the use of sequences, which will not mutate like the actual ... Voir le document complet
3
Kinesin-1 regulates antigen cross-presentation through the scission of tubulations from early endosomes in dendritic cells
... thank the staff at Imagine Institute’s animal facility for their assistance and especially Jade ...with the spinning disk microscopy, Sebastian Montealegre for his technical assistance in DC functional ... Voir le document complet
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The origins of serialization
... community of about 400 speakers, who call themselves Teko. The Teko people live in two areas of French Guiana: in the western part, next to the Maroni river (the border with ... Voir le document complet
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