[PDF] Top 20 Stromal cell contribution to human follicular lymphoma pathogenesis.
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Stromal cell contribution to human follicular lymphoma pathogenesis.
... nodes, cell interactions, stromal cells B CELL LYMPHOMA MICROENVIRONMENT Human mature B cell lymphomas represent a heterogeneous group of neoplasias characterized by recurrent ... Voir le document complet
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Human Lymphoid Stromal Cells Contribute to Polarization of Follicular T Cells Into IL-4 Secreting Cells
... lymphoid stromal cells initially identi fied as triggering T-cell recruitment and dynamic motion in secondary lymphoid ...+ follicular T cells are important players of B-cell maturation and ... Voir le document complet
10
IL-4/CXCL12 loop is a key regulator of lymphoid stroma function in follicular lymphoma
... ETHODS Human tissue and cell samples Subjects were recruited under institutional review board approval following informed consent process according to the declaration of Helsinki and the French ... Voir le document complet
31
Constitutive AKT activation in follicular lymphoma.
... common to a wide variety of human tumors ...As to FL, AKT activation may also be related to ...interesting to further analyze phosphoryl- ation events in FL patient samples at the ... Voir le document complet
10
Resistance to gemcitabine in a human follicular lymphoma cell line is due to partial deletion of the deoxycytidine kinase gene.
... cells to 25 µM in the resistant variant, RL-G. Xenografts of both cell lines developed in nude mice were treated with repeated injections of ...similarly to those of untreated animals, demonstrating ... Voir le document complet
14
Resistance to the proteasome inhibitors: Lessons from multiple myeloma and mantle cell lymphoma
... mantle cell lymphoma (MCL), two of the most challenging B-cell malignancies in western ...resistance to this agent remains a major limitation for further development of its therapeutic ... Voir le document complet
32
CD4-positive T-helper cell responses to the PASD1 protein in patients with diffuse large B-cell lymphoma
... antigens to elicit long-lasting CTL responses to the target ...necessary to achieve a sufficient immune response, a strategy potential- ly leading to the induction of ...performed to ... Voir le document complet
9
Akt2 knock-down reveals its contribution to human lung cancer cell proliferation, growth, motility, invasion and endothelial cell tube formation
... cancer cell invasion and perhaps - by extrapolation - in ...tectable. To assess whether Akt1 and -2 plays a role in angiogenesis, we conducted a study on the forma- tion of capillary-like structures in ... Voir le document complet
15
Results from the Belgian mantle cell lymphoma registry
... Main demographics are summarized in Table 1 . The median age at diagnosis was 64 years (range 23–96 years). A histogram of age distribution is displayed in Fig. 1 . We compared the results of the total group of patients ... Voir le document complet
8
Management of Drug Resistance in Mantle Cell Lymphoma
... of lymphoma mutational landscape, it came out that different epigenetic deregulations were associated with B lymphomagenesis and lymphoma progression ...capacity to targeting epigenetic readers of ... Voir le document complet
26
CD4 T-Helper Responses to the Anaplastic Lymphoma Kinase (ALK) Protein in Patients with ALK-Positive Anaplastic Large-Cell Lymphoma
... response to ALK (4–6) but also of ALK- specific CTLs in patients with ALK-positive ALCL (6, ...response to tumors (8–10) means it is important to identify CD4 + Th cell peptide-binding ... Voir le document complet
5
Stromal cells regulate malignant B-cell spatial organization, survival, and drug response in a new 3D model mimicking lymphoma tumor niche
... Stromal cells regulate malignant B-cell spatial organization, survival, and drug response in a new 3D model mimicking lymphoma tumor niche Claire Lamaison, Simon Latour, Nelson Hélaine, [r] ... Voir le document complet
51
Radioimmunotherapy-augmented BEAM chemotherapy vs BEAM alone as the high-dose regimen for autologous stem cell transplantation (ASCT) in relapsed follicular lymphoma (FL): a retrospective study of the EBMT Lymphoma Working Party
... demonstrated to be well tolerated in the initial phase I/II ...aggressive lymphoma confirmed the previously reported observations that the addition of Z to high-dose BEAM is safe and not associated ... Voir le document complet
6
Cytolytic T-cell response to the PASD1 cancer testis antigenin patients with diffuse large B-cell lymphoma
... pared to those results obtained from the control cultures (cells stimulated with the irrelevant HIV peptide or medium only, P < ...B-cell lymphoma. Thirteen patients responded to two or ... Voir le document complet
12
Monte Carlo dosimetry of a realistic multicellular model of follicular lymphoma in a context of radioimmunotherapy
... In each MALC, absorbed doses for β - particle emitters are greater than for Auger electron emit-. 365[r] ... Voir le document complet
35
Molecular features of hepatosplenic T-cell lymphoma unravels potential novel therapeutic targets.: Molecular Signature of Hepatosplenic T-cell Lymphoma
... three cell suspensions (from spleen, bone marrow and blood), two of which were enriched in tumor cells (samples HSTL_01 and ...according to the WHO criteria 8 ... Voir le document complet
41
Targeting early B-cell receptor signaling induces apoptosis in leukemic mantle cell lymphoma.
... leading to activation of various signaling pathways including ...signal to variable extents of constitutive phosphorylation forming a 53–56 kDa doublet (Figure 4A and Additional file 3: Figure ... Voir le document complet
15
Contribution of MT1-MMP and of Human Laminin-5 Gamma2 Chain Degradation to Mammary Epithelial Cell Migration
... MCF10A cell migration We found that Ln-5, a potential substrate for MT1-MMP, is preferentially deposited by MT1-MMP- overexpressing migratory MCF10A cells at the periphery of the ...shown to be deposited ... Voir le document complet
14
Contribution of MT1-MMP and of human laminin-5 gamma2 chain degradation to mammary epithelial cell migration.
... connected to a video CCD camera (Cohu 4700, San Diego, CA) and a video monitor (PVM 1371, Sony, Japan), so as to measure the outgrowth ...area. To analyse and quantify the migratory speeds and ... Voir le document complet
15
Apple cell wall contribution to fruit viscoelasticitic properties
... 'MFTIZ GSVJU RVBMJUZ SFMJFT PO WBSJPVT DIBSBDUFST BNPOH XIJDI UFYUVSF JNQBDU QSPEVDUJPO QSP DFTTJOH BOE DPOTVNFS BDDFQUBODF 5P EBUF UFYUVSF JT TUJMM QPPSMZ DPOUSPMMFE BT TUSVDUVSBM QIZTJ[r] ... Voir le document complet
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