[PDF] Top 20 Where to Stand with Stromal Cells and Chronic Synovitis in Rheumatoid Arthritis?

... used in preclinical RA joint models with the aim of delaying/preventing these invasive and hyperproliferative stromal phenotypes [ 61 – 64 ...induction in response to intrinsic ... Voir le document complet

... structures with T and B-cell differentiation ...neogenesis and maintenance is a reversible consequence of chronic inflammation found in RA, like in other inflamed sites of ... Voir le document complet

... procedure, where long follow-up periods are necessary in order to assess noticeable changes of the artic- ular cartilage ...(MMP-3) and YKL-40 have also been used for assessing the extent of ... Voir le document complet

... skewing and the presence of the SE, the main genetic susceptibility marker associated with RA ...erosion and bone destruction, regardless of therapy [ 34 – 36 ...proposed where skewed XCI is a ... Voir le document complet

... randomized to switch to either a 2 nd anti- TNFα or a non-anti- TNFα agent ...assessed in 272 patients with available serum samples using enzyme-linked immunosorbent assay (ELISA) (Quantikine, ... Voir le document complet

... effects with no report of serious adverse events besides some immediate type I hypersensitivity (pruritis, rash, fever) in <15% of patients ( 21 ...safety and efficacy of the intravenous ... Voir le document complet

... sidered to be important for the selective homing of Th1 cells and not Th2 cells ...E-selectin and VCAM-1 was significantly reduced by anti-TNF therapy ...Th1 cells into RA ... Voir le document complet

... led to an open pilot trial in five patients with UCMD or BM trea- ted orally with CsA for 1 month ...dysfunction and decrease of apoptosis of muscle cells following this ... Voir le document complet

... inflammation and osteoclastogenesis in the arthritic joint, are fundamental to RA ...] In this study we demonstrated that a newly discovered cytokine, IL-34, is expressed by the synovial ... Voir le document complet

... We thank the other members of the scientific committee of the SMART study: Pr. J. Sibilia (Strasbourg, France), Pr. J. Tebib (Lyon, France), Pr. B. Combe (Montpellier, France), and Pr. X. Le Loët (Rouen, France). ... Voir le document complet

... Santé’ and ‘Commission Nationale de l’Informatique et des ...2008 and 2010. Centres were informed that including patients in this observa- tional registry would not interfere with their ... Voir le document complet

... study to detect differences. However, this series of patients with RA-DB is one of the largest ever studied, and differences in age at onset of DB and genetic background appear ... Voir le document complet

... limited and so the results will need to be confirmed in an independent ...Moreover, to demonstrate that high sodium excretion is a risk factor for the development of RA, large prospective ... Voir le document complet

... homeostasis and may have immunomodulatory ...was to investigate the role of vitamin D receptor gene (VDR) in rheumatoid arthritis ...1544410) and TaqI C4T (rs 731236) were ... Voir le document complet

... change and the frequency of its minor allele T has been recently and repeatedly shown to be increased in patients with rheumatoid arthritis (RA) ...risk to ... Voir le document complet

... severity, and organ specific risk and (v) develop new diagnostic tests ...pathogenetic and pathophysiological processes identification as demonstrated in several types of diseases: cancer ... Voir le document complet

... association with coronary artery disease [ 18 ...cancer and less conclusive for some other cancers [ 19 ...ated with increased CVD and risk of oropharyngeal, laryngeal, oesophageal, liver, ... Voir le document complet

... miRNAs in the serum of RA patients is more likely reflecting distinct composition and activation status of the haematopoietic compartment than of the joint space; suggesting that the systemic inflammatory ... Voir le document complet

... search to papers published after 2007 to ensure the data presented were recent and economically ...screened, with only those publications that reported the results of a valuation study for one ... Voir le document complet

... Materials and Methods Sera studied Sera from patients and blood donors were collected (Laboratoire d’Immunologie, Hôpital Saint-Antoine, Paris, France), with approval of the Committee of the ... Voir le document complet